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1. 发明申请

WO1998022498A1 CYCLIC HEXAPEPTIDES HAVING ANTIBIOTIC ACTIVITY 审中-公开
标题翻译：具有抗生素活性的循环下一步
公开(公告)号：WO1998022498A1
公开(公告)日：1998-05-28
申请号：PCT/JP1997004194
申请日：1997-11-18
申请人： FUJISAWA PHARMACEUTICAL CO., LTD. , KANASAKI, Ryuichi , TAKASE, Shigehiro , HASHIMOTO, Michizane , HATANAKA, Hiroshi , SAKAMOTO, Kazutoshi , HASHIMOTO, Seiji , SHIRAISHI, Nobuyuki , OHKI, Hidenori , KAWABATA, Kohji
发明人： FUJISAWA PHARMACEUTICAL CO., LTD.
IPC分类号： C07K07/56
CPC分类号： C07K7/56 , A61K38/00
摘要： This invention relates to new polypeptide compounds represented by formula (I), wherein R is as defined in the description or a salt thereof, which have antimicrobial activities (especially, antifungal activities), inhibitory activity on beta -1,3-glucan synthase, to a process for preparation thereof, to a pharmaceutical composition comprising the same, and to a method for the prophylactic and/or therapeutic treatment of infectious diseases including Pneumocystis carinii infection (e.g. Pneumocystis carinii pneumonia) in a human being or an animal.
摘要翻译：本发明涉及由式（I）表示的新的多肽化合物，其中R 1如说明书中所定义或其盐，其具有抗微生物活性（特别是抗真菌活性），对β- 葡聚糖合酶，其制备方法，含有该组合物的药物组合物，以及用于预防和/或治疗人或动物中包括卡氏肺囊虫感染（例如肺孢子虫肺炎）的感染性疾病的方法。

2. 发明申请

WO1997001575A1 SUBSTANCE WF16616, PROCESS FOR PRODUCTION THEREOF, AND USE THEREOF 审中-公开
标题翻译：物质WF16616，其生产方法及其用途
公开(公告)号：WO1997001575A1
公开(公告)日：1997-01-16
申请号：PCT/JP1996001725
申请日：1996-06-21
申请人： FUJISAWA PHARMACEUTICAL CO., LTD. , OKUDAIRA, Terumi , TSURUMI, Yasuhisa , HATANAKA, Hiroshi , KINO, Toru , HASHIMOTO, Seiji
发明人： FUJISAWA PHARMACEUTICAL CO., LTD.
IPC分类号： C07K07/06
CPC分类号： C07K7/56 , A61K38/00
摘要： Substance WF16616 represented by chemical formula (1) or medicinally acceptable salts thereof. This substance has antimicrobial effects, particularly an excellent antifungal effect.
摘要翻译：由化学式（1）表示的物质WF16616或其医药上可接受的盐。该物质具有抗菌作用，特别是极好的抗真菌作用。

3. 发明申请

WO1995027318A1 RESONATOR AND FILTER USING IT 审中-公开
标题翻译：谐振器和滤波器使用它
公开(公告)号：WO1995027318A1
公开(公告)日：1995-10-12
申请号：PCT/JP1995000629
申请日：1995-03-31
申请人： NIHON DENGYO KOSAKU CO., LTD. , HATANAKA, Hiroshi
发明人： NIHON DENGYO KOSAKU CO., LTD.
IPC分类号： H01P07/00
CPC分类号： H01P1/20 , H01P1/205 , H01P1/208 , H01P7/00 , H01P7/04 , H01P7/06
摘要： A resonator constituted of an external conductor (1), a dielectric plate (2), a resonating capacitance element, an input terminal (5) and an output terminal (6). The plate (2) is fixed at the upper and lower ends to the upper and lower walls of the conductor (1), respectively. The resonating capacitance element is constituted of electrodes composed of metallic thin layers or metallic plates respectively provided on the front and back of the plate (2). The lower end of one of the electrodes is electrically connected to the lower wall of the conductor (1), and a gap is formed between the upper end of the one electrode and the upper wall of the conductor (1). The upper end of the other electrode is electrically connected to the upper wall of the conductor (1), and a gap is formed between the lower end of the other electrode and the lower wall of the conductor (1).
摘要翻译：由外部导体（1），电介质板（2），谐振电容元件，输入端子（5）和输出端子（6）构成的谐振器。板（2）分别固定在导体（1）的上壁和下壁上端和下端。共振电容元件由分别设置在板（2）的前后的金属薄层或金属板构成的电极构成。一个电极的下端电连接到导体（1）的下壁，并且在一个电极的上端和导体（1）的上壁之间形成间隙。另一个电极的上端电连接到导体（1）的上壁，并且在另一个电极的下端和导体（1）的下壁之间形成间隙。

4. 发明申请

WO1993002203A1 FR901451 SUBSTANCE, PROCESS FOR PREPARATION THEREOF AND USE THEREOF 审中-公开
标题翻译： FR901451物质，其制备方法及其用途
公开(公告)号：WO1993002203A1
公开(公告)日：1993-02-04
申请号：PCT/JP1992000894
申请日：1992-07-14
申请人： FUJISAWA PHARMACEUTICAL CO., LTD. , HATANAKA, Hiroshi , TAKASE, Shigehiro , FUJITA, Takashi , OKAMOTO, Masanori , OKUHARA, Masakuni
发明人： FUJISAWA PHARMACEUTICAL CO., LTD.
IPC分类号： C12P01/04
CPC分类号： C12P1/04 , A61K31/00 , C07G17/00 , C12R1/01 , Y10S435/822
摘要： A new FR901451 substance which is produced by culturing an FR901451 substance-producing strain of the genus Flexibacter in a nutrient medium, this new substance possessing a human leukocyte elastase-inhibiting activity.
摘要翻译：一种新的FR901451物质，其通过在营养培养基中培养柔性菌属的FR901451物质生产菌株而生产，该新物质具有人白细胞弹性蛋白酶抑制活性。

5. 发明申请

WO0118007A3 METHOD FOR SEPARATING LACTONE-CONTAINING HIGH-MOLECULAR WEIGHT COMPOUNDS 审中-公开
标题翻译：用于分离含有LACTONE的高分子量重量化合物的方法
公开(公告)号：WO0118007A3
公开(公告)日：2001-07-26
申请号：PCT/JP0006023
申请日：2000-09-05
申请人： FUJISAWA PHARMACEUTICAL CO , HIGAKI TOMOJI , YOSHIYASU TAKASHI , HASHIMOTO NORIHIRO , HONDA KEIJI , HATANAKA HIROSHI , YAMASHITA MICHIO
发明人： HIGAKI TOMOJI , YOSHIYASU TAKASHI , HASHIMOTO NORIHIRO , HONDA KEIJI , HATANAKA HIROSHI , YAMASHITA MICHIO
IPC分类号： C12P17/16 , B01D15/00 , B01D15/08 , B01D15/42 , C07D498/18
CPC分类号： C07D498/18
摘要： A method for separating a lactone-containing high-molecular weight compound comprising subjecting a mixture of a lactone-containing high-molecular weight compound having, as its side-chain, at least one of a lower alkenyl group and a lower alkoxy group and its analogous compound(s) to either one or both steps in any order of a step (A) for adsorbing the mixture to a nonionic adsorption resin and eluting with an aqueous solvent containing silver ions, and a step (B) for adsorbing the mixture to a basic active alumina and eluting with an organic solvent to separate each of the compounds.
摘要翻译：一种分离含内酯的高分子量化合物的方法，包括使具有作为其侧链的含内酯的高分子量化合物与低级链烯基和低级烷氧基中的至少一种的内酯的混合物及其和用于将混合物吸附到非离子吸附树脂上并用含有银离子的含水溶剂洗脱的步骤（A）的任何一个或两个步骤的任何一个或两个步骤的类似化合物和用于将混合物吸附到碱性活性氧化铝，并用有机溶剂洗脱以分离每种化合物。

6. 发明申请

WO1993017991A1 TETRALIN DERIVATIVES AS HMG-CoA REDUCTASE INHIBITORS 审中-公开
标题翻译：作为HMG-CoA还原酶抑制剂的四环素衍生物
公开(公告)号：WO1993017991A1
公开(公告)日：1993-09-16
申请号：PCT/JP1993000266
申请日：1993-03-03
申请人： FUJISAWA PHARMACEUTICAL CO., LTD. , GOTO, Toshio , SHIBATA, Toshihiro , OKUHARA, Masakuni , SAKAMOTO, Kazutoshi , HATANAKA, Hiroshi , TAKASE, Shigehiro , SATO, Tomoko
发明人： FUJISAWA PHARMACEUTICAL CO., LTD.
IPC分类号： C07C59/54
CPC分类号： C07C69/732 , C07C59/54 , C07D309/30 , C12P7/42 , C12P17/06 , C12P17/12
摘要： This invention relates to novel tetralin derivatives having inhibitory activity against an enzyme 3-hydroxy-3-methylglutaryl-coenzyme A reductase and represented by general formula (I) in which R1 is hydrogen or acetyl, R2 is carboxy and R3 is hydroxy, or R2 and R3 may form lactone, and pharmaceutical acceptable salts thereof, to processes for the preparation thereof and to a pharmaceutical composition comprising the same.
摘要翻译：本发明涉及对3-羟基-3-甲基戊二酰辅酶A还原酶具有抑制活性的新型四氢化萘衍生物，其通式（I）表示，其中R 1为氢或乙酰基，R 2为羧基且R 3为羟基，或R 2为和R3可以形成内酯及其药学上可接受的盐，其制备方法和包含其的药物组合物。

7. 发明申请

WO1997009298A1 PRODUCTION OF AN IMMUNOSUPPRESSANT USING MICROORGANISMS 审中-公开
标题翻译：使用微生物生产免疫抑制剂
公开(公告)号：WO1997009298A1
公开(公告)日：1997-03-13
申请号：PCT/JP1996002309
申请日：1996-08-16
申请人： FUJISAWA PHARMACEUTICAL CO., LTD. , HINO, Motohiro , HATANAKA, Hiroshi , TAKASE, Shigehiro , TSURUMI, Yasuhisa , KINA, Toru , HASHIMOTO, Seiji
发明人： FUJISAWA PHARMACEUTICAL CO., LTD.
IPC分类号： C07C229/30
CPC分类号： C12P13/001 , C07C229/30
摘要： This invention relates to a new bioactive compound, WF10917 substance or a salt thereof, having immunosuppressing activity, to a process for preparation thereof and to a pharmaceutical composition comprising the same, said compound having formula (I).
摘要翻译：本发明涉及具有免疫抑制活性的新的生物活性化合物WF10917物质或其盐，其制备方法和含有该生物活性化合物的药物组合物，所述具有式（I）的化合物。

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