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1. 发明申请

WO1997041246A1 THERMOPHILIC METHANOTROPHS FOR HIGH TEMPERATURE OXIDATIONS 审中-公开
标题翻译：用于高温氧化的热化甲烷
公开(公告)号：WO1997041246A1
公开(公告)日：1997-11-06
申请号：PCT/US1997007044
申请日：1997-04-25
申请人： UNITED STATES ENVIRONMENTAL PROTECTION AGENCY
发明人： UNITED STATES ENVIRONMENTAL PROTECTION AGENCY , VESPER, Stephen, J. , DAVIS-HOOVER, Wendy, Jo
IPC分类号： C12P01/04
CPC分类号： C12R1/01 , A62D3/02 , A62D2101/20 , A62D2101/22 , B09C1/10 , C02F3/2806 , C02F3/34 , C12N9/0071 , Y02E50/343
摘要： The invention is a consortium of thermophilic methanotrophic organisms in culture medium containing said consortium reproduced at temperatures of 50 DEG C to 80 DEG C, said consortium being comprised primarily of ovoid or rod-shaped organisms. The consortium can be instilled into soil or water to degrade pollutants, especially hydrocarbons and substituted hydrocarbons.
摘要翻译：本发明是在含有在50℃至80℃的温度下再生的所述联合体的培养基中的嗜热甲烷营养生物体的联合体，所述联合体主要由卵形或棒状生物组成。这些财团可以灌注到土壤或水中以降解污染物，特别是碳氢化合物和取代的碳氢化合物。

2. 发明申请

WO1990010079A1 PROCESS AND MEANS FOR THE MICROBIOLOGICAL REMEDIATION OF POLLUTED SOIL AND MICROORGANISMS FOR USE IN SAID PROCESS 审中-公开
标题翻译：污染土壤微生物的微生物修复方法和使用手段
公开(公告)号：WO1990010079A1
公开(公告)日：1990-09-07
申请号：PCT/FI1990000055
申请日：1990-02-27
申请人： ALKO LTD. , VALO, Risto, Juhani , HÄGGBLOM, Max, Mikael , SALKINOJA-SALONEN, Mirja
发明人： ALKO LTD.
IPC分类号： C12P01/04
CPC分类号： C12R1/32 , B09C1/10 , C12N11/08 , C12R1/01
摘要： The invention relates to a process for the microbiological remediation of soil polluted by chlorophenols, the soil to be decontaminated being composted with the chlorophenol-degrading microorganisms and the conditions being adjusted so that they favour for the growth of the microorganisms. According to the invention such chlorophenol-degrading microorganisms of the genus Rhodococcus and Mycobacterium are preferably used which are capable of degrading the chlorophenols also in field conditions. According to the invention the microorganisms are preferably immobilized in a solid porous support.
摘要翻译：本发明涉及一种用氯酚污染的土壤进行微生物修复的方法，要被去污的土壤被氯酚降解微生物堆肥并调整条件使其有利于微生物的生长。根据本发明，优选使用能够在现场条件下降解氯酚的红球菌属和分枝杆菌属的氯酚降解微生物。根据本发明，微生物优选固定在固体多孔载体中。

3. 发明申请

WO1982001721A1 CULTURE MEDIUM,EXTRACT,ACTIVE MIXTURE,ACTIVE COMPOUNDS,AS WELL AS THE MICROBIOLOGICAL PREPARATION THEREOF,AND MICROORGANISM USED THEREIN 审中-公开
标题翻译：培养基，提取物，活性混合物，活性化合物，以及其微生物制剂及其使用的微生物
公开(公告)号：WO1982001721A1
公开(公告)日：1982-05-27
申请号：PCT/EP1981000183
申请日：1981-11-19
申请人： BIOTECHN FORSCHUNG GMBH , GERTH KLAUS , KOHL WERNER , AUGUSTINIAK HERMANN , STEINMETZ HEINRICH , IRSCHIK HERBERT , REICHENBACH HANS , HOEFLE GERHARD , TROWITZSCH WOLFRAM , KEMMER TORSTEN , KUNZE BRIGITTE , SANTOSO SENTOT
发明人： BIOTECHN FORSCHUNG GMBH
IPC分类号： C12P01/04
CPC分类号： C12R1/01 , C12P1/04
摘要： Culture medium, extract, active mixture and compounds with antibiotic activity obtained by microbiological process by means of the microorganism DSM 1888.

4. 发明申请

WO1998022611A1 PRODUCTION AND RECOVERY OF ORGANIC ACIDS 审中-公开
标题翻译：有机酸的生产和回收
公开(公告)号：WO1998022611A1
公开(公告)日：1998-05-28
申请号：PCT/US1997020121
申请日：1997-11-04
申请人： A.E. STALEY MANUFACTURING COMPANY
发明人： A.E. STALEY MANUFACTURING COMPANY , EYAL, Aharon, M. , LEHNHARDT, William, F.
IPC分类号： C12P01/04
CPC分类号： C12P7/56 , C12P7/40 , Y10S435/803
摘要： A process is described for producing organic acids such as lactic acid. The process includes the steps of producing lactic acid by fermentation, resulting in an aqueous fermentation broth containing lactic acid, and adding a calcium base, such as calcium carbonate, to the fermentation broth, thereby producing calcium lactate in the broth. Biomass is removed from the broth, thereby leaving an aqueous solution or dispersion of calcium lactate. The calcium lactate is reacted with a source of ammonium ions, such as ammonium carbonate, or a mixture of ammonia and carbon dioxide, thereby producing an ammonium lactate. Contaminating cations can be removed by ion exchange. The free lactic acid or a derivative thereof can be separated from the ammonium ions, preferably by salt-splitting electrodialysis.
摘要翻译：描述了用于生产有机酸如乳酸的方法。该方法包括通过发酵生产乳酸的步骤，得到含有乳酸的含水发酵液，并向发酵液中加入钙碱如碳酸钙，从而在肉汤中产生乳酸钙。从肉汤中除去生物质，从而留下乳酸钙的水溶液或分散体。将乳酸钙与铵离子源如碳酸铵或氨和二氧化碳的混合物反应，从而产生乳酸铵。污染的阳离子可以通过离子交换去除。游离乳酸或其衍生物可以与铵离子分离，优选通过盐分解电渗析。

5. 发明申请

WO1980000573A1 COMPOUNDS HAVING THE EMPIRIC SUMMARY FORMULA C25H33N3O3S2 审中-公开
标题翻译：具有有效摘要公式C25H33N3O3S2的化合物
公开(公告)号：WO1980000573A1
公开(公告)日：1980-04-03
申请号：PCT/DE1979000100
申请日：1979-08-31
申请人： GES BIOTECHNOLOGISCHE FOR , AUGUSTINIAK H , TROWITZSCH W , REIFENSTAHL G , REICHENBACH H , KUNZE B , IRSCHIK H , WRAY V , GROTJAHN L , GERTH K , KEMMER T
发明人： GES BIOTECHNOLOGISCHE FOR
IPC分类号： C12P01/04
CPC分类号： C12R1/01 , C07D277/30 , C07D277/56 , C12P1/04 , C12P17/167
摘要： Culture medium and extract containing compounds having an antibiotic activity, having the empiric summary formula C25H33N3O3S2. In addition, the invention includes the active compounds, preparation processes of the culture medium, of the extract and of the active compounds, as well as a process for further treatment of the extract.

6. 发明申请

WO1995020673A1 ORGANO-PHOSPHORUS COMPOUNDS AS ACTIVATORS OF GAMMA DELTA T CELLS 审中-公开
标题翻译：有机磷化合物作为GAMMA DELTA T细胞的激活剂
公开(公告)号：WO1995020673A1
公开(公告)日：1995-08-03
申请号：PCT/FR1995000092
申请日：1995-01-26
申请人： CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.) , INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE , BONNEVILLE, Marc , CONSTANT, Patricia, Marie-Claude , FOURNIE, Jean-Jacques , PUZO, Germain
发明人： CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.) , INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE
IPC分类号： C12P01/04
CPC分类号： A61K39/04 , A61K31/66 , A61K31/7072 , A61K38/46 , A61K38/465 , C07F9/091 , C07F9/113 , C07F9/3891 , C07F9/65586 , C07G17/00 , C07H19/10 , C12P1/06 , C12R1/32 , C12Y301/03 , C12Y301/04 , C12Y306/01009 , Y02A50/412 , A61K2300/00
摘要： Non-peptide hydrosoluble organo-phosphorus containing compound for use as a human T gamma 9 delta 2 cell activator, comprising at least one acidolabile ester bond of phosphoric acid. The activating properties of said compound in relation to lymphocytes are lost when it is placed in the presence of an enzymatic mixture comprising at least one phosphoric phosphohydrolase monoester and at least one phosphoric phosphohydrolase diester. The invention also concerns a method for the preparation, isolation or characterization of such a compound and compositions and pharmaceutical uses thereof.
摘要翻译：用作人Tγ9Δ2细胞活化剂的非肽可溶性有机磷化合物，其包含磷酸的至少一种酸不溶性酯键。所述化合物相对于淋巴细胞的活化性质在其包含至少一种磷酸磷酸酯单酯和至少一种磷酸磷酸二酯酯的酶混合物存在时丧失。本发明还涉及这种化合物及其组合物及其药物用途的制备，分离或表征的方法。

7. 发明申请

WO1995010625A1 DNA ENCODING 1,3-BETA-D GLUCAN SYNTHASE SUBUNITS 审中-公开
标题翻译： DNA编码1,3-β-D葡萄糖合成酶亚基
公开(公告)号：WO1995010625A1
公开(公告)日：1995-04-20
申请号：PCT/US1994011498
申请日：1994-10-11
申请人： MERCK & CO., INC. , DOUGLAS, Cameron, M. , CLEMAS, Joseph , CHREBET, Gary, L. , EL-SHEERBEINI, Mohammed , FOOR, Forrest , KAHN, Jennifer, Nielsen , KELLY, Rosemarie , MARRINAN, Jean, A. , MORIN, Nancy, R. , ONISHI, Janet, C. , PARENT, Stephen, Arthur , RAMADAN, Naasa, M. , SHEI, Gan-Ju
发明人： MERCK & CO., INC.
IPC分类号： C12P01/04
CPC分类号： C12N9/1051 , A61K38/00 , C07K14/395
摘要： DNA molecules encoding proteins involved in biosynthesis of 1,3-beta-D glucan are identified, cloned, expressed and used in in vitro assays to screen for antifungal compounds, including compounds that affect cell wall biosynthesis. The invention includes but is not limited to the purified DNA molecules, assays employing the DNA molecules, proteins encoded by the DNA molecules, cells expressing the DNA molecules and altered forms of the molecules.
摘要翻译：编码参与1,3-β-D葡聚糖生物合成的蛋白质的DNA分子被鉴定，克隆，表达并用于体外测定以筛选抗真菌化合物，包括影响细胞壁生物合成的化合物。本发明包括但不限于纯化的DNA分子，使用DNA分子的测定，由DNA分子编码的蛋白，表达DNA分子的细胞和分子的改变形式。

8. 发明申请

WO1993002203A1 FR901451 SUBSTANCE, PROCESS FOR PREPARATION THEREOF AND USE THEREOF 审中-公开
标题翻译： FR901451物质，其制备方法及其用途
公开(公告)号：WO1993002203A1
公开(公告)日：1993-02-04
申请号：PCT/JP1992000894
申请日：1992-07-14
申请人： FUJISAWA PHARMACEUTICAL CO., LTD. , HATANAKA, Hiroshi , TAKASE, Shigehiro , FUJITA, Takashi , OKAMOTO, Masanori , OKUHARA, Masakuni
发明人： FUJISAWA PHARMACEUTICAL CO., LTD.
IPC分类号： C12P01/04
CPC分类号： C12P1/04 , A61K31/00 , C07G17/00 , C12R1/01 , Y10S435/822
摘要： A new FR901451 substance which is produced by culturing an FR901451 substance-producing strain of the genus Flexibacter in a nutrient medium, this new substance possessing a human leukocyte elastase-inhibiting activity.
摘要翻译：一种新的FR901451物质，其通过在营养培养基中培养柔性菌属的FR901451物质生产菌株而生产，该新物质具有人白细胞弹性蛋白酶抑制活性。

9. 发明申请

WO1991018104A1 INDH ENZYME COMPOSITIONS AND THEIR METHODS OF USE 审中-公开
标题翻译： INDH ENZYME组合物及其使用方法
公开(公告)号：WO1991018104A1
公开(公告)日：1991-11-28
申请号：PCT/US1991003630
申请日：1991-05-23
申请人： AUTOMEDIX SCIENCES, INC.
发明人： AUTOMEDIX SCIENCES, INC. , MURTFELDT, Robert , BREAM, Allan, J. , MCCARTHY, Kathryn
IPC分类号： C12P01/04
CPC分类号： C12N9/0069 , A61K38/00 , C12N11/06 , C12Y113/99003 , Y10S435/802 , Y10S435/814 , Y10S435/818 , Y10S435/874
摘要： The present invention relates to an INDH enzyme composition that contains a substantially isolated INDH enzyme and methods for preparing and using an INDH enzyme-containing composition.
摘要翻译：本发明涉及含有基本上分离的INDH酶的INDH酶组合物以及用于制备和使用含INDH酶的组合物的方法。

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