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1. 发明申请

WO2012176065A2 METHOD COMPOSITIONS AND DEVICE FOR PREPARING CYTOLOGICAL SPECIMENS 审中-公开
标题翻译：用于制备细胞学样本的方法组合物和装置
公开(公告)号：WO2012176065A2
公开(公告)日：2012-12-27
申请号：PCT/IB2012/001261
申请日：2012-06-22
申请人： BIOTECHNOLOGY DEVELOPERS, S.A. , GONZAGA, Roy, Mora , WISCOVITCH, Robin, A. , GONZALEZ, Juan, Valdes
发明人： GONZAGA, Roy, Mora , WISCOVITCH, Robin, A. , GONZALEZ, Juan, Valdes
IPC分类号： G01N1/30
CPC分类号： G01N1/30 , G01N1/2813 , G01N2001/4088
摘要： The invention relates to a method for preparing specimens from tissue samples for cytology microscopic examination, and includes inventive compositions and a device used in said method. The invention also includes a diagnostic kit comprising the inventive compositions and device.
摘要翻译：本发明涉及一种用于从组织样品制备用于细胞学显微镜检查的标本的方法，并且包括本发明的组合物和在所述方法中使用的装置。本发明还包括包含本发明组合物和装置的诊断试剂盒。

2. 发明申请

WO2012172129A1 PROCEDIMIENTO OPTIMIZADO PARA LA OBTENCION DE PEPTIDOS INHIBIDORES DE LA ENZIMA CONVERTIDORA DE ANGIOTENSINA; PEPTIDOS INHIBIDORES Y ALIMENTO QUE LOS COMPRENDE 审中-公开
标题翻译：用于获得转氨酶转化酶抑制性肽，抑制性肽和含有其的食物的优化方法
公开(公告)号：WO2012172129A1
公开(公告)日：2012-12-20
申请号：PCT/ES2011/070551
申请日：2011-07-27
申请人： QUEIZUAR, S.L. , PEREIRA RAMOS, Benigno , PEREIRA RODRIGUEZ, Angel , ESTEVEZ TELLE, Natalia , FUCIÑOS GONZALEZ, Juan Pablo , RUA RODRIGUEZ, Maria Luisa , PASTRANA CASTRO, Lorenzo
发明人： PEREIRA RAMOS, Benigno , PEREIRA RODRIGUEZ, Angel , ESTEVEZ TELLE, Natalia , FUCIÑOS GONZALEZ, Juan Pablo , RUA RODRIGUEZ, Maria Luisa , PASTRANA CASTRO, Lorenzo
IPC分类号： C12P21/06 , A23J3/34
CPC分类号： A23J3/343 , A23J1/205 , A23L33/18 , C07K4/12 , C12P21/06
摘要： Procedimiento optimizado para obtener péptidos inhibidores de la actividad de la ECA, en el que están presentes las etapas de ultrafiltración de suero lácteo para obtener un concentrado de suero, hidrólisis enzimática, ultrafiltración de hidrolizados y separación de ios péptidos inhibidores, que comprende una selección y adición de una mezcla adecuada en proporción y cantidad de dos proteasas de origen microbiano y acción complementaria a dicho concentrado de suero, para la hidrólisis de éste, con el fin de obtener péptidos con un porcentaje de inhibición de la ECA superior ai 70% y un índice iC50 de 30 a 100 Mg/ml.
摘要翻译：本发明涉及一种获得ACE抑制肽的优化方法，包括以下步骤：超滤乳清以获得血清浓缩物，酶水解，水解产物的超滤和抑制肽的分离。该方法还包括通过合适的比例和量的两种微生物蛋白酶的选择和添加，所述两种微生物蛋白酶与血清浓缩物具有互补作用以进行水解，以获得ACE抑制百分比大于70的肽％和IC 50指数在30和100μg/ ml之间。

3. 发明申请

WO2012009824A3 SELF - ASSEMBLAGE CONTAINER AND MANUFACTURING METHOD THEREOF 审中-公开
标题翻译：自组装容器及其制造方法
公开(公告)号：WO2012009824A3
公开(公告)日：2012-05-10
申请号：PCT/CL2011000041
申请日：2011-07-21
申请人： COMPANIA PATENTES DEL PACIFICO SPA , RIO GONZALEZ JUAN JOSE , QUEROL PUIG SANTIAGO ANTONIO
发明人： RIO GONZALEZ JUAN JOSE , QUEROL PUIG SANTIAGO ANTONIO
IPC分类号： B31B5/00 , B31B17/00 , B65D5/30
CPC分类号： B65D5/323 , B31B50/20 , B65D5/001 , B65D11/1873 , Y10T29/49826
摘要： The present invention refers to a self - assemblable container, preferably manufactured from ecologic materials such as standard fiberboard, comprising as its main structural elements a bottom, two longitudinal sides and two transverse sides of a basically rectangular shape having cauterized perimetrical faces to prevent moisture penetration into the structural elements that make up the container, thus providing long term structural stiffness to the perimetrical faces of the container's structural elements comparable to that of the fiberboard surface. The invention also refers to a method of manufacturing the structural elements of a self - assemblable container by means of perimetrical laser cutting that by reason of the extremely high cutting temperature causes a reaction of the natural resins contained in the raw material and the resulting perimetrical cauterization.
摘要翻译：本发明涉及一种自组装容器，其优选地由诸如标准纤维板的生态材料制成，其包括作为其主要结构元件的底部，两个纵向侧面和基本上矩形形状的两个横向侧面，其具有烧灼的周边面以防止湿气渗透进入构成容器的结构元件，从而为容器的结构元件的周边面提供与纤维板表面相当的长周期结构刚度。本发明还涉及通过周边激光切割制造自组装容器的结构元件的方法，由于极高的切割温度导致原料中包含的天然树脂与所得的周边烧灼炉的反应。

4. 发明申请

WO2011157759A1 BEVERAGE DISPENSER WITH IMPROVED POWDER DOSING SYSTEM 审中-公开
标题翻译：具有改进的粉末剂量系统的饮料分配器
公开(公告)号：WO2011157759A1
公开(公告)日：2011-12-22
申请号：PCT/EP2011/059957
申请日：2011-06-15
申请人： NESTEC S.A. , NELISSEN, Radboud , MURPHY, Richard Luke , GONZALEZ, Juan J. , BARDIN, Ennio
发明人： NELISSEN, Radboud , MURPHY, Richard Luke , GONZALEZ, Juan J. , BARDIN, Ennio
IPC分类号： A47J31/40
CPC分类号： A47J31/404 , A47J31/401
摘要： The invention concerns a dispensing machine for producing beverages from a beverage ingredient powder comprising : - at least one powder storing and dosing sub-assemblies, each of them comprising : a buffer tank able to be connected to a food or beverage ingredient powder container, a dosing device for metering a dose of a beverage ingredient powder, - reconstitution means for preparing a beverage from a dose of the food or beverage ingredient powder, wherein each of the buffer tank comprises a tube for guiding the powder from the container connection means to the dosing device, the first portion of said tube emerging on the dosing device being vertical.
摘要翻译：本发明涉及一种用于从饮料成分粉末生产饮料的分配机，包括： - 至少一个粉末储存和计量子组件，每个组件包括：缓冲罐，其能够连接到食品或饮料成分粉末容器，用于计量一定剂量的饮料成分粉末的计量装置， - 用于从所述食品或饮料成分粉末的剂量制备饮料的重构装置，其中每个所述缓冲罐包括用于将粉末从所述容器连接装置引导到所述容器连接装置的管计量装置中，出现在计量装置上的所述管的第一部分是垂直的。

5. 发明申请

WO2010024847A3 REAR-INSTALLABLE FIBER OPTIC MODULES AND EQUIPMENT 审中-公开
标题翻译：可再安装的光纤模块和设备
公开(公告)号：WO2010024847A3
公开(公告)日：2010-06-03
申请号：PCT/US2009004549
申请日：2009-08-07
申请人： CORNING CABLE SYS LLC , COOKE TERRY L , KLAVUHN TORY A , DEAN JR DAVID L , GARCIA JUAN , MARIANO ELMER , LOPEZ MANUEL , GONZALEZ JUAN M
发明人： COOKE TERRY L , KLAVUHN TORY A , DEAN JR DAVID L , GARCIA JUAN , MARIANO ELMER , LOPEZ MANUEL , GONZALEZ JUAN M
IPC分类号： G02B6/44
CPC分类号： G02B6/4455 , G02B6/3897 , G02B6/4452
摘要： Fiber optic equipment that supports one or more rear-installable fiber optic modules is disclosed. The fiber optic equipment is comprised of a chassis defining a front end and a rear section. At least one guide system is disposed in the chassis and configured to receive at least one fiber optic module. The guide system may be provided in the form of a rail guide system. The at least one guide system receives the at least one fiber optic module from the rear section on the chassis and is configured to guide the fiber optic module toward the front end of the chassis. In this manner, a technician can make fiber optic connections to fiber optic modules and also install the fiber optic modules into the fiber optic equipment from the rear section of the chassis to reduce time and/or labor in making fiber optic connections.
摘要翻译：公开了支持一个或多个可后部安装的光纤模块的光纤设备。光纤设备由限定前端和后端部分的底盘组成。至少一个引导系统设置在底架中并且构造成接收至少一个光纤模块。导向系统可以以导轨系统的形式提供。所述至少一个引导系统从底座上的后部接收至少一个光纤模块，并且被配置为将光纤模块朝向底座的前端引导。以这种方式，技术人员可以与光纤模块进行光纤连接，并且还可以将光纤模块从机箱后部安装到光纤设备中，以减少进行光纤连接的时间和/或人力。

6. 发明申请

WO2006089050A3 SYSTEM AND METHOD FOR MAINTAINING AIR INFLATABLE MATTRESS CONFIGURATION 审中-公开
标题翻译：用于维护空气可充气配置的系统和方法
公开(公告)号：WO2006089050A3
公开(公告)日：2008-07-24
申请号：PCT/US2006005517
申请日：2006-02-16
申请人： KCI LICENSING INC , PHILLIPS BRUCE L , VRZALIK JOHN H , PARKER JEFFREY S , SMITH KENNETH R , GONZALEZ JUAN L , BENDELE KEVIN W , OLIVA MICHAEL R , SLIMPIN PAUL D , LINA CESAR Z , STACY PETER CHARLES , BEARD MARK STEPHEN JAMES , ROBSON GODFREY CHARLES ALEXAND
发明人： PHILLIPS BRUCE L , VRZALIK JOHN H , PARKER JEFFREY S , SMITH KENNETH R , GONZALEZ JUAN L , BENDELE KEVIN W , OLIVA MICHAEL R , SLIMPIN PAUL D , LINA CESAR Z , STACY PETER CHARLES , BEARD MARK STEPHEN JAMES , ROBSON GODFREY CHARLES ALEXAND
IPC分类号： A47C27/10
CPC分类号： A61G7/05769 , A61G2203/40 , A61G2203/42 , A61G2203/46 , G16H40/63
摘要： A system and method for maintaining an air inflation mattress configuration sufficient for patient support and comfort. Infrared illumination levels are measured within individual or groups of inflated mattress chambers. A staggered approach to illumination monitoring of chambers or sections to eliminate crosstalk between the infrared sensors is carried out. Distributed microprocessor controllers established in a network configuration utilizing controller network protocols reduces the wiring and connections necessary for the assembled system. Various mattress cushion construction techniques, such as sewing and or RF welding methods, are used for the creation of individual chambers utilizing specific types of IR translucent, transparent or reflective materials. The construction of the cushions and bladders in the system includes the use of various types of fabrics with low to high air loss qualities as required. The overall mattress assembly, including the control systems and the methodologies associated with such control systems, provide a unique approach to the maintenance of a consistently comfortable patient support surface. The use of a handheld unit for both programming the system and downloading information about the operation of the system is also anticipated. The specific cushion construction designs associated with the head, body, and foot cushion components of the mattress are tailored to operate specifically with the control capabilities (sensors and air flow regulators) of the invention.
摘要翻译：一种用于维持充气床垫配置的系统和方法，足以使患者支撑和舒适。在充气床垫室的个别或组内测量红外照明水平。执行了用于消除红外传感器之间的串扰的室或部分的照明监视的交错方法。使用控制器网络协议在网络配置中建立的分布式微处理器控制器减少组装系统所需的接线和连接。使用诸如缝纫和/或RF焊接方法的各种床垫构造技术用于利用特定类型的IR半透明，透明或反射材料来创建各个室。系统中的垫子和囊的构造包括根据需要使用具有低至高空气损失特性的各种类型的织物。包括控制系统和与这种控制系统相关联的方法的整体床垫组件为维持一贯舒适的患者支撑表面提供了独特的方法。还预期使用手持设备来编程系统和下载关于系统的操作的信息。与床垫的头部，身体和脚垫部件相关联的具体衬垫结构设计被定制为具有本发明的控制能力（传感器和气流调节器）的特定操作。

7. 发明申请

WO2008070631A2 METHOD AND APPARATUS FOR PREVENTING THE FORMATION OF A PLASMA INHIBITING SUBSTANCE 审中-公开
标题翻译：防止形成等离子体抑制物质的方法和设备
公开(公告)号：WO2008070631A2
公开(公告)日：2008-06-12
申请号：PCT/US2007086303
申请日：2007-12-03
申请人： ADVANCED ENERGY IND INC , TOMASEL FEMANDO GUSTAVO , MAUCK JUSTIN , SHABALIN ANDREW , SHAW DENIS M , GONZALEZ JUAN JOSE
发明人： TOMASEL FEMANDO GUSTAVO , MAUCK JUSTIN , SHABALIN ANDREW , SHAW DENIS M , GONZALEZ JUAN JOSE
IPC分类号： C23C16/00
CPC分类号： H01J37/32357 , H01J37/32495
摘要： A system and method for preventing formation of a plasma-mhibiting substance withm a plasma chamber is provided In one embodiment, an apparatus that includes a barrier component configuied to be disposed within a plasma chamber. The barrier component includes a wall that defines a plasma formation region where a chemically- reducing species is formed fiom a fluid. A portion of the wall is formed of a substance that is substantially inert to the chemically-reducing species. The wall prevents the chemically-reducing species from interacting with an mnei surface of the plasma chamber to form a conductive substance. The barpei component also includes an opening in fluid communication with the plasma formation region. The fluid is introduced into the plasma formation region via the opening.
摘要翻译：提供了一种用于防止在等离子体室中形成等离子体禁止物质的系统和方法。在一个实施例中，提供了一种包括配置为设置在等离子体室内的屏障组件的设备。屏障部件包括限定等离子体形成区域的壁，其中化学还原物质由流体形成。壁的一部分由对化学还原物质基本惰性的物质形成。该壁防止化学还原物质与等离子体室的姆内表面相互作用以形成导电物质。 barpei组件还包括与等离子体形成区域流体连通的开口。流体经由开口被引入等离子体形成区域。

8. 发明申请

WO2006089050A2 SYSTEM AND METHOD FOR MAINTAINING AIR INFLATABLE MATTRESS CONFIGURATION 审中-公开
标题翻译：用于维护空气可充气配置的系统和方法
公开(公告)号：WO2006089050A2
公开(公告)日：2006-08-24
申请号：PCT/US2006/005517
申请日：2006-02-16
申请人： KCI LICENSING, INC. , PHILLIPS, Bruce, L. , VRZALIK, John, H. , PARKER, Jeffrey, S. , SMITH, Kenneth, R. , GONZALEZ, Juan, L. , BENDELE, Kevin, W. , OLIVA, Michael, R. , SLIMPIN, Paul, D. , LINA, Cesar, Z. , STACY, Peter, Charles , BEARD Mark, Stephen, James , ROBSON, Godfrey, Charles, Alexander
发明人： PHILLIPS, Bruce, L. , VRZALIK, John, H. , PARKER, Jeffrey, S. , SMITH, Kenneth, R. , GONZALEZ, Juan, L. , BENDELE, Kevin, W. , OLIVA, Michael, R. , SLIMPIN, Paul, D. , LINA, Cesar, Z. , STACY, Peter, Charles , BEARD Mark, Stephen, James , ROBSON, Godfrey, Charles, Alexander
IPC分类号： A47C27/10
CPC分类号： A61G7/05769 , A61G2203/40 , A61G2203/42 , A61G2203/46 , G06F19/00 , G16H40/63
摘要： A system and method for maintaining an air inflation mattress configuration sufficient for patient support and comfort. Infrared illumination levels are measured within individual or groups of inflated mattress chambers. A staggered approach to illumination monitoring of chambers or sections to eliminate crosstalk between the infrared sensors is carried out. Distributed microprocessor controllers established in a network configuration utilizing controller network protocols reduces the wiring and connections necessary for the assembled system. Various mattress cushion construction techniques, such as sewing and or RF welding methods, are used for the creation of individual chambers utilizing specific types of IR translucent, transparent or reflective materials. The construction of the cushions and bladders in the system includes the use of various types of fabrics with low to high air loss qualities as required. The overall mattress assembly, including the control systems and the methodologies associated with such control systems, provide a unique approach to the maintenance of a consistently comfortable patient support surface. The use of a handheld unit for both programming the system and downloading information about the operation of the system is also anticipated. The specific cushion construction designs associated with the head, body, and foot cushion components of the mattress are tailored to operate specifically with the control capabilities (sensors and air flow regulators) of the invention.
摘要翻译：一种用于维持充气床垫配置的系统和方法，足以使患者支撑和舒适。在充气床垫室的个别或组内测量红外照明水平。执行了用于消除红外传感器之间的串扰的室或部分的照明监视的交错方法。使用控制器网络协议在网络配置中建立的分布式微处理器控制器减少组装系统所需的接线和连接。使用诸如缝纫和/或RF焊接方法的各种床垫构造技术用于利用特定类型的IR半透明，透明或反射材料来创建各个室。系统中的垫子和囊的构造包括根据需要使用具有低至高空气损失特性的各种类型的织物。包括控制系统和与这种控制系统相关联的方法的整体床垫组件为维持一贯舒适的患者支撑表面提供了独特的方法。还预期使用手持设备来编程系统和下载关于系统的操作的信息。与床垫的头部，身体和脚垫部件相关联的具体缓冲结构设计被定制为具有本发明的控制能力（传感器和空气流量调节器）的特定操作。

9. 发明申请

WO2004063271A2 STRUCTURED BAROPLASTIC MATERIALS 审中-公开
标题翻译：结构化的塑性材料
公开(公告)号：WO2004063271A2
公开(公告)日：2004-07-29
申请号：PCT/US2004/000334
申请日：2004-01-07
申请人： MASSACHUSETTS INSTITUTE OF TECHNOLOGY , MAYES, Anne, M. , RYU, Sang, Woog , ACAR, Metin, H. , GONZALEZ, Juan, A.
发明人： MAYES, Anne, M. , RYU, Sang, Woog , ACAR, Metin, H. , GONZALEZ, Juan, A.
IPC分类号： C08L
CPC分类号： C08L51/003 , B29C43/006 , B29C47/0016 , B29C47/04 , B29K2105/162 , B82Y30/00 , C08F257/02 , C08F265/04 , C08F265/06 , C08F285/00 , C08F287/00 , C08F293/005 , C08J3/005 , C08J3/126 , C08J5/18 , C08L51/006 , C08L53/00 , Y10T428/2929 , C08L2666/02
摘要： The present invention provides a series of baroplastic materials, and systems and methods of making and using such baroplastic materials. In one aspect of the invention, polymeric particles are provided that can be used to produce baroplastic materials under certain pressures and/or below certain temperatures. In one set of embodiments, the polymeric particles include an inner "core" region and an outer "shell" region. In some cases, more than one "shell" region may be present. In another arrangement the particles can include materials, or domains, in nanoscale proximity with each other. Non-particulate materials can also be processed in accordance with the invention. In another aspect of the invention, the invention provides for polymeric particles that can be processed and/or recycled multiple times, without causing significant degradation or alteration in the physical and/or chemical properties of the polymer. In yet another aspect, the invention provides compositions able to form baroplastic materials upon the application of certain pressures, where the composition includes at least two chemically distinct materials in nanoscale proximity to each other. In still another aspect of the invention, a method of mixing two polymers upon the application of pressure is provided.
摘要翻译：本发明提供了一系列的压塑材料，以及制造和使用这种压塑材料的系统和方法。在本发明的一个方面中，提供了可在一定压力和/或低于特定温度下用于生产压塑材料的聚合物颗粒。在一组实施例中，聚合物颗粒包括内部“芯” 区域和外部“壳” 地区。在一些情况下，多于一个的“壳” 区域可能存在。在另一种布置中，颗粒可以包括彼此纳米级接近的材料或区域。根据本发明也可以处理非颗粒材料。在本发明的另一方面，本发明提供了可以多次加工和/或再循环的聚合物颗粒，而不引起聚合物的物理和/或化学性质的显着降解或改变。在又一个方面，本发明提供了能够在施加一定压力时形成压塑材料的组合物，其中所述组合物包含至少两种化学上不同的纳米级彼此接近的材料。在本发明的另一方面，提供了一种在施加压力时混合两种聚合物的方法。

10. 发明申请

WO2003006457A1 VARIOLIN DERIVATIVES AND THEIR USE AS ANTITUMOR AGENTS 审中-公开
标题翻译： VARIOLIN衍生物及其作为抗菌剂的用途
公开(公告)号：WO2003006457A1
公开(公告)日：2003-01-23
申请号：PCT/GB2002/003197
申请日：2002-07-11
申请人： PHARMA MAR, S.A. , REMUIÑAN, Modesto , GONZALEZ, Juan Jose , DEL POZO, Carlos , FRANCESCH, Andrés , CUEVAS, Carmen , MUNT, Simon , MANZANARES, Ignacio
发明人： REMUIÑAN, Modesto , GONZALEZ, Juan Jose , DEL POZO, Carlos , FRANCESCH, Andrés , CUEVAS, Carmen , MUNT, Simon , MANZANARES, Ignacio
IPC分类号： C07D401/06
CPC分类号： C07D213/64 , C07D213/78 , C07D239/38 , C07D401/06 , C07D401/14 , C07D409/14 , C07D471/06 , C07D471/14
摘要： Variolin derivatives of formula (5) are provided, wherein the substituent groups defined by X 2 , R 1 , R 2 , R 3 , R 6 , R 7 and R 12 are each independently selected from the group consisting of H, OH, OR', SH, SR', SOR', SO 2 R', NO 2 , NH 2 , NHR', N(R') 2 , NHCOR', NHSO 2 R', CN, halogen, =O, C(=O)H, C(=O)R', CO 2 H, CO 2 R', carboxyalkyl, C 1 -C 12 alkyl, C 2 -C 12 alkenyl, C 2 -C 12 alkynyl, substituted or unsubstituted aryl, substituted or unsubstituted aralkyl and substituted or unsubstituted heteroaromatic; wherein each of the R' groups is independently selected from the group consisting of H, OH, SH, N0 2 , NH 2 , CN, halogen, =O, C(=O)H, C(=O)CH 3 , CO 2 H, CO 2 CH 3 , C 1 -C 12 alkyl, C 2 -C 12 alkenyl, C 2 -C 12 alkynyl, aryl, aralkyl and heteroaromatic; wherein the pairs of groups R 1 and R 2 , R 2 and R 3 , R 3 and R 12 , R 12 and R 6 , or R 6 and R 7 may be joined into a carbocyclic or heterocyclic ring system.
摘要翻译：提供了式（5）的异喹啉衍生物，其中由X 2，R 1，R 2，R 3，R 6，R 7和R 12定义的取代基各自独立地选自H，OH，OR'，SH，SR' SOR'，SO2R'，NO2，NH2，NHR'，N（R'）2，NHCOR'，NHSO2R'，CN，卤素，= O，C（= O）H，C（= O） CO 2 R'，羧基烷基，C 1 -C 12烷基，C 2 -C 12烯基，C 2 -C 12炔基，取代或未取代的芳基，取代或未取代的芳烷基和取代或未取代的杂芳族; 其中每个R'基团独立地选自H，OH，SH，NO 2，NH 2，CN，卤素，= O，C（= O）H，C（= O）CH 3，CO 2 H，CO 2 CH 3， C 1 -C 12烷基，C 2 -C 12烯基，C 2 -C 12炔基，芳基，芳烷基和杂芳族; 其中基团R 1和R 2，R 2和R 3，R 3和R 12，R 12和R 6，或R 6和R 7的对可以连接成碳环或杂环系。

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