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1. 发明申请

WO2013052808A3 DUAL STAPLE CARTRIDGE FOR SURGICAL STAPLER 审中-公开
标题翻译：手术刀架双刀盒
公开(公告)号：WO2013052808A3
公开(公告)日：2013-08-08
申请号：PCT/US2012058969
申请日：2012-10-05
申请人： ETHICON ENDO SURGERY INC , KRUMANAKER DAVID T , SIMMS ROBERT J , GOLDBERG EDIT , OSBORNE THOMAS P
发明人： KRUMANAKER DAVID T , SIMMS ROBERT J , GOLDBERG EDIT , OSBORNE THOMAS P
IPC分类号： A61B17/072 , A61B17/064
CPC分类号： A61B17/072 , A61B17/07292 , A61B2017/0645 , A61B2017/07228 , A61B2017/07271 , A61B2017/2927 , F04C2270/041
摘要： A surgical stapler (10) includes and end effector (12) configured to receive an upper staple cartridge (160) and a lower staple cartridge (120). The lower staple cartridge includes staple drivers (43) disposed at a non-perpendicular or oblique angle. The staple drivers may be oppositely angled relative to the perpendicular. The staple drivers may further be coupled to an actuation member that pivots the staple drivers to the perpendicular prior to stapling. The actuation members may be actuated by the firing bar (14) and/or by a wedge sled (41). The upper staple cartridge may also include angled staple drivers that are pivotable to the perpendicular. The upper staple cartridge and/ or the lower staple cartridge may also include staple forming pockets (53). Alternatively, one staple driver may be perpendicular and second staple driver may be at a non-perpendicular angle. The second staple driver may be actuated into an angled stamped recess (230).
摘要翻译：手术吻合器（10）包括构造成容纳上钉仓（160）和下钉仓（120）的末端执行器（12）。下钉仓包括以非垂直或倾斜角设置的缝钉驱动器（43）。订书钉驱动器可以相对于垂直线相对成角度。订书钉驱动器可以进一步联接到在装订之前将订书钉驱动器枢转到垂直的致动构件。致动构件可以由击发杆（14）和/或楔形滑板（41）致动。上钉仓还可以包括可枢转到垂直线的成角度的钉驱动器。上钉仓和/或下钉仓还可以包括钉形成袋（53）。或者，一个订书钉驱动器可以是垂直的，并且第二订书钉驱动器可以处于非垂直的角度。第二钉驱动器可以被致动成成角度的冲压凹部（230）。

2. 发明申请

WO2013052808A2 DUAL STAPLE CARTRIDGE FOR SURGICAL STAPLER 审中-公开
标题翻译：手术刀架双刀盒
公开(公告)号：WO2013052808A2
公开(公告)日：2013-04-11
申请号：PCT/US2012/058969
申请日：2012-10-05
申请人： ETHICON ENDO-SURGERY, INC. , KRUMANAKER, David, T. , SIMMS, Robert, J. , GOLDBERG, Edit , OSBORNE, Thomas, P.
发明人： KRUMANAKER, David, T. , SIMMS, Robert, J. , GOLDBERG, Edit , OSBORNE, Thomas, P.
IPC分类号： A61B17/072 , A61B17/064
CPC分类号： A61B17/072 , A61B17/07292 , A61B2017/0645 , A61B2017/07228 , A61B2017/07271 , A61B2017/2927 , F04C2270/041
摘要： A surgical stapler includes and end effector configured to receive an upper staple cartridge and a lower staple cartridge. The lower staple cartridge includes staple drivers disposed at a non-perpendicular or oblique angle. The staple drivers may be oppositely angled relative to the perpendicular. The staple drivers may further be coupled to an actuation member that pivots the staple drivers to the perpendicular prior to stapling. The actuation members may be actuated by the firing bar and/or by a wedge sled. The upper staple cartridge may also include angled staple drivers that are pivotable to the perpendicular. The upper staple cartridge and/or the lower staple cartridge may also include staple forming pockets. Alternatively, one staple driver may be perpendicular and second staple driver may be at a non-perpendicular angle. The second staple driver may be actuated into an angled stamped recess.
摘要翻译：手术吻合器包括和末端执行器，其构造成接纳上钉仓和下钉仓。下钉仓包括以非垂直或倾斜角设置的钉驱动器。订书钉驱动器可以相对于垂直线相对成角度。订书钉驱动器可以进一步联接到在装订之前将订书钉驱动器枢转到垂直的致动构件。致动构件可以由击发杆和/或楔形滑轨致动。上钉仓还可以包括可枢转到垂直线的成角度的钉驱动器。上钉仓和/或下钉仓还可以包括钉形成袋。或者，一个订书钉驱动器可以是垂直的，并且第二订书钉驱动器可以处于非垂直的角度。第二订书钉驱动器可以被致动成成角度的冲压凹部。

3. 发明申请

WO2013003445A1 TETRA-PYRIDINE COMPOUNDS AND COMPOSITION FOR PROTECTING CELLS, TISSUES AND ORGANS AGAINST ISCHEMIA-REPERFUSION INJURY 审中-公开
标题翻译：四氯吡啶化合物和组合物，用于保护细胞，组织和反体间代谢损伤的器官
公开(公告)号：WO2013003445A1
公开(公告)日：2013-01-03
申请号：PCT/US2012/044376
申请日：2012-06-27
申请人： APPELBAUM, Jerachmiel Y. , TSHUVA GOLDBERG, Edit , ATHENA CARDIONET LTD. , YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY, LTD. , GERAGHTY, Erin
发明人： APPELBAUM, Jerachmiel Y. , TSHUVA GOLDBERG, Edit
IPC分类号： C07D213/36 , A61K31/444 , A61P39/00 , A61P9/00
CPC分类号： C07D213/36 , A01N1/0226
摘要： The invention provides a novel tetra-pyridine compound and a composition containing this compound for protecting and preserving cells, tissues and organs against ischemia-reperfusion injury. A method and use of the tetra-pyridine compound for preventing or treating ischemia-reperfusion injury or for protecting and preserving excorporeal tissue or organ from ischemia and oxygen radical-related damage are also provided.
摘要翻译：本发明提供新颖的四吡啶化合物和含有该化合物的组合物，用于保护和保存细胞，组织和器官免于缺血再灌注损伤。还提供了四吡啶化合物用于预防或治疗缺血再灌注损伤或保护和保存体外组织或器官缺血和氧自由基相关损伤的方法和用途。

4. 发明申请

WO2007059801A1 APPLICATOR DEVICE FOR APPLYING A MULTI-COMPONENT FLUID 审中-公开
标题翻译：用于应用多组分流体的应用器件
公开(公告)号：WO2007059801A1
公开(公告)日：2007-05-31
申请号：PCT/EP2005/056154
申请日：2005-11-22
申请人： OMRIX BIOPHARMACEUTICALS S.A. , GOLDBERG, Edit
发明人： GOLDBERG, Edit
IPC分类号： A61B17/00
CPC分类号： A61B17/00491 , A61B2017/00495 , A61B2017/00526 , A61M5/19
摘要： Disclosed is an applicator device ( 10) for applying a multi-component fluid, especially a multi-component tissue glue, comprising a plurality of substantially cylindrical supply containers (12) for respectively one component of the fluid to be applied, each supply container ( 12) having a front end (16) with an out¬ let opening (18), a rear end (22) opposite to the front end ( 16), and a slidably displaceable piston (24) arranged within the supply container ( 12) and having a piston rod (26) extending out of the rear end (22) for operating the piston (24). Moreover, the applicator device includes a manifold (72) having terminal ends (50,58) with a first port for fluid connection with the front ends (16) of the supply containers (12), the manifold (72) further having internal channels (62) extending from the first ports of the terminal ends (50,58) to an outlet site. Finally, also a holding element (38) for holding the supply containers ( 12), and a coupling clement (74) extending from the holding element (38) and having a connection end (76) connected to the manifold (72) arc pro¬ vided, wherein the connection end (76) of the coupling element (74) is bonded to the manifold (72).
摘要翻译：公开了一种用于施加多组分流体，特别是多组分组织胶的施加器装置（10），其包括多个基本上圆柱形的供给容器（12），用于分别被施加的流体的一个部件，每个供应容器 12）具有带有外露开口（18）的前端（16），与前端（16）相对的后端（22）和布置在供给容器（12）内的可滑动位移的活塞（24）并具有延伸出后端（22）的活塞杆（26），用于操作活塞（24）。此外，涂抹器装置包括具有终端（50,58）的歧管（72），其具有用于与供应容器（12）的前端（16）流体连接的第一端口，歧管（72）还具有内部通道（62）从所述终端（50,58）的所述第一端口延伸到出口位置。最后，还有用于保持供应容器（12）的保持元件（38）和从保持元件（38）延伸并具有连接到歧管（72）的连接端（76）的连接件（74）其中联接元件（74）的连接端（76）与歧管（72）结合。

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