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1. 发明申请

WO2012018923A1 IMPLANTABLE DRUG DELIVERY DEVICES FOR GENITOURINARY SITES 审中-公开
标题翻译：用于遗传性网站的可植入药物递送装置
公开(公告)号：WO2012018923A1
公开(公告)日：2012-02-09
申请号：PCT/US2011/046439
申请日：2011-08-03
申请人： TARIS BIOMEDICAL, INC. , DICESARE, Paul , RADZIUNAS, Jeffrey , BARNES, Andrew , BRITSCHOCK, Eric , SUTTON, David
发明人： DICESARE, Paul , RADZIUNAS, Jeffrey , BARNES, Andrew , BRITSCHOCK, Eric , SUTTON, David
IPC分类号： A61K9/22
CPC分类号： A61M31/002
摘要： Implantable drug delivery devices are provided lo have a deployment shape for implantation in the body and a retention shape for retention in the body. The device may have one or more elongated drug reservoirs containing a drug, mid the drug reservoir may be formed from a deformable material. In one case, a first filament is attached to the first end of the drug reservoir and second filament is attached to the second end of the drug reservoir, wherein a fastener is positioned about the first and second filaments to permit shortening and prevent lengthening of the filaments with reference to the ends of the daig reservoir, as a means for transfonning the device from the implantation shape to the retention shape.
摘要翻译：可植入药物输送装置具有用于植入体内的展开形状和用于保持在体内的保持形状。该装置可以具有包含药物的一个或多个细长的药物储存器，药物储存器的中间可以由可变形材料形成。在一种情况下，第一丝被附着到药物储存器的第一端，第二丝连接到药物储存器的第二端，其中紧固件围绕第一和第二长丝定位以允许起酥油和防止延长参考Daig储存器的端部的细丝作为用于将装置从植入形状转换为保持形状的装置。

2. 发明申请

WO2007136631A2 SUTURE LOCK FASTENING DEVICE 审中-公开
标题翻译：舒适锁紧装置
公开(公告)号：WO2007136631A2
公开(公告)日：2007-11-29
申请号：PCT/US2007011671
申请日：2007-05-16
申请人： BARD INC C R , PAGE EDWARD C , GUTELIUS PATRICK , FERREIRA DANIAL , RADZIUNAS JEFFREY , DICESARE PAUL
发明人： PAGE EDWARD C , GUTELIUS PATRICK , FERREIRA DANIAL , RADZIUNAS JEFFREY , DICESARE PAUL
IPC分类号： A61B17/00 , A61B17/04
CPC分类号： A61B17/0487 , A61B17/0467 , A61B17/0485 , A61B2017/045 , A61B2017/0488
摘要： A suture lock fastening device to cinch a suture in a suture lock, cut the suture end, and deploy the suture lock in response to a single movement of a user. The fastening device includes a fastening head with a retainer that is configured to hold a suture lock in the fastening head. To release the suture lock from the fastening head, the retainer is irreversibly deformed. The fastening device may include an axially movable cutter with a cutting edge to sever the ends of the suture close to the suture lock. A threading device may be preloaded into the fastening device to facilitate threading the suture through the fastening device.
摘要翻译：一种缝合线锁紧装置，用于将缝合线缝合在缝合线锁中，切割缝合线端部，并且响应于使用者的单次运动而部署缝合线锁。紧固装置包括具有保持器的紧固头部，该保持器构造成将缝合线锁定在紧固头部中。为了从紧固头释放缝合锁，保持器不可逆地变形。紧固装置可以包括具有切割刃的可轴向移动的切割器，以将缝合线的端部切割成靠近缝合线锁定。穿线装置可以被预加载到紧固装置中以便于缝合线穿过紧固装置。

3. 发明申请

WO2013026043A1 TISSUE REMOVAL SYSTEM 审中-公开
标题翻译：组织拆卸系统
公开(公告)号：WO2013026043A1
公开(公告)日：2013-02-21
申请号：PCT/US2012/051487
申请日：2012-08-17
申请人： HOLOGIC, INC. , SULLIVAN, Roy H. , ADAMS, Ronald D. , BARNES, Andrew , RADZIUNAS, Jeffrey , PAUL, Joe , DICESARE, Paul
发明人： SULLIVAN, Roy H. , ADAMS, Ronald D. , BARNES, Andrew , RADZIUNAS, Jeffrey , PAUL, Joe , DICESARE, Paul
IPC分类号： A61B10/02 , A61B10/04 , A61B17/32
CPC分类号： A61B10/0291 , A61B10/0266 , A61B10/0275 , A61B10/0283 , A61B10/04 , A61B17/320016 , A61B17/42 , A61B90/30 , A61B2010/0208 , A61B2010/0225 , A61B2017/00389 , A61B2017/00685 , A61B2017/320028 , A61B2017/32004 , A61B2017/320064 , A61B2017/4216 , A61B2217/005 , A61B2217/007 , A61M1/0047
摘要： A tissue removal device (1000) includes an outer tubular member (1008) coupled to a housing (1002) and a having a tissue resection window (1014), an inner tubular member (1016) slidably disposed within the outer tubular member, a tissue trap (1032) having a sealed interior in fluid communication with a vacuum chamber (1030), an open proximal end of the inner tubular member being disposed within the tissue trap interior, and an actuator (1020) moveably coupled to the housing and operatively connected to a movable piston (1028) in the vacuum chamber (1030), such that movement of the actuator relative to the housing generates a vacuum in the tissue trap.
摘要翻译：组织去除装置（1000）包括联接到壳体（1002）并具有组织切除窗口（1014）的外部管状构件（1008），可滑动地设置在外部管状构件内的内部管状构件（1016），组织捕集器（1032）具有与真空室（1030）流体连通的密封内部，内部管状构件的敞开的近端设置在组织捕获器内部，以及可移动地联接到壳体并可操作地连接的致动器到真空室（1030）中的可移动活塞（1028），使得致动器相对于壳体的运动在组织阱中产生真空。

4. 发明申请

WO2008124650A1 METHOD, SYSTEM AND DEVICE FOR TISSUE REMOVAL 审中-公开
标题翻译：用于组织去除的方法，系统和装置
公开(公告)号：WO2008124650A1
公开(公告)日：2008-10-16
申请号：PCT/US2008/059504
申请日：2008-04-04
申请人： INTERLACE MEDICAL, INC. , GRUBER, William, Harwick , ADAMS, Ronald, David , CHIN, Albert, Chun-chi , LITSCHER, Eric, Karl , SULLIVAN, Roy, Hewett , DICESARE, Paul , RADZIUNAS, Jeffrey , VIGLIOTTI, Daniel , KNODEL, Bryan, Dale , DANIELS, Chris, Scott , VITITOE, Kevin, J. , LORENZ, Michael, Anthony , KOLADA, Paul, P. , CRISP, Ryan, Scott , CICENAS, Chris, William , MORA, Ludwin, M. , BURCHFIELD, Brent, Lee
发明人： GRUBER, William, Harwick , ADAMS, Ronald, David , CHIN, Albert, Chun-chi , LITSCHER, Eric, Karl , SULLIVAN, Roy, Hewett , DICESARE, Paul , RADZIUNAS, Jeffrey , VIGLIOTTI, Daniel , KNODEL, Bryan, Dale , DANIELS, Chris, Scott , VITITOE, Kevin, J. , LORENZ, Michael, Anthony , KOLADA, Paul, P. , CRISP, Ryan, Scott , CICENAS, Chris, William , MORA, Ludwin, M. , BURCHFIELD, Brent, Lee
IPC分类号： A61B19/00 , A61B17/42
CPC分类号： A61B17/32002 , A61B17/29 , A61B17/3201 , A61B17/32053 , A61B17/32056 , A61B17/320725 , A61B17/320783 , A61B17/42 , A61B2017/00685 , A61B2017/2905 , A61B2017/320004 , A61B2017/320064 , A61B2017/320775 , A61B2017/4216 , A61B2018/1407 , A61B2217/005 , A61M1/0082
摘要： A method and device for tissue removal. The device may be used to remove uterine fibroids and other abnormal gynecological tissue. According to one embodiment, the device includes a housing, an outer tube, and an inner tube. The outer tube is fixed to the housing and includes a side window proximate to its distal end. The side window may have sloped proximal and distal ends. The inner tube has a distal end positioned within the outer tube, the distal end being adapted to rotate and, at the same time, to move back and forth past the side window, with the rotational and translational movement of the inner tube being independently controllable. The distal end of the inner tube may have an external bevel. Suction is applied to the proximal end of the inner tube to draw tissue into the side window and to remove resected tissue through the inner tube.
摘要翻译：一种用于组织去除的方法和装置。该装置可用于去除子宫肌瘤和其他异常妇科组织。根据一个实施例，该装置包括外壳，外管和内管。外管固定在壳体上并且包括靠近其远端的侧窗。侧窗可能具有倾斜的近端和远端。内管具有定位在外管内的远端，远端适于旋转，并且同时来回移动经过侧窗，内管的旋转和平移运动可独立控制。内管的远端可以具有外部斜面。将吸力施加到内管的近端以将组织拉入侧窗并通过内管去除切除的组织。

5. 发明申请

WO2007126657A1 AN IMPLANTABLE CATHETHER AND METHOD OF USING SAME 审中-公开
标题翻译：可植入的导管及其使用方法
公开(公告)号：WO2007126657A1
公开(公告)日：2007-11-08
申请号：PCT/US2007/007035
申请日：2007-03-21
申请人： RITA MEDICAL SYSTEMS, INC. , SMITH, David, A. , MASTRI, Dominick, L. , RADZIUNAS, Jeffrey, P. , DICESARE, Paul , KENNY, James, Steven
发明人： SMITH, David, A. , MASTRI, Dominick, L. , RADZIUNAS, Jeffrey, P. , DICESARE, Paul , KENNY, James, Steven
IPC分类号： A61M25/00
CPC分类号： A61M25/0097 , A61M25/0009 , A61M25/0014 , A61M39/06 , A61M39/0606 , A61M39/10 , A61M2027/004 , A61M2039/062 , A61M2039/1027
摘要： A catheter (10) for implantation into a patient having a catheter tube (20) having a distal end (22), a means for trimming (80) the distal end of the catheter tube after subcutaneous insertion of the tip (24) of the catheter lumen into a desired position within the patient to form a trimmed end portion, and a means for selectively positioning each respective lumen of the trimmed end portion of the catheter tube into fluid communication with the respective first end of one attachment tube (50). The attachment tube is select fluid communication with a desired medical device.
摘要翻译：一种用于植入具有具有远端（22）的导管（20）的患者的患者的导管（10），用于在所述导管的尖端（24）皮下插入之后修整（80）所述导管的远端的装置导管内腔进入患者内的期望位置以形成修剪的端部，以及用于选择性地将导管管的修剪端部的每个相应内腔定位成与一个附接管（50）的相应第一端流体连通的装置。附件管是与期望的医疗装置的选择性流体连通。

6. 发明申请

WO2006110405A3 METHODS AND APPARATUS FOR THERMAL REGULATION OF A BODY 审中-公开
标题翻译：一种身体温度调节的方法和装置
公开(公告)号：WO2006110405A3
公开(公告)日：2007-07-05
申请号：PCT/US2006012561
申请日：2006-04-03
申请人： MEDCOOL INC , LENNOX CHARLES D , ALLAIRE KEVIN , RADZIUNAS JEFFREY , THOMPSON JOHN , DICESARE PAUL , HIRES GREG , MELSKY GERALD
发明人： LENNOX CHARLES D , ALLAIRE KEVIN , RADZIUNAS JEFFREY , THOMPSON JOHN , DICESARE PAUL , HIRES GREG , MELSKY GERALD
IPC分类号： A61F7/00
CPC分类号： A61F7/02 , A61F2007/0002 , A61F2007/0011 , A61F2007/0056
摘要： A thermal regulation system includes a thermal exchange collar for application to a neck of a patient, a thermal regulation pad for application to a body region, such as an axilla region of the patient, and a thermal regulation cap for application to a head of the patient.
摘要翻译：热调节系统包括用于应用于患者颈部的热交换套环，用于应用于身体区域（例如患者的腋窝区域）的热调节垫，以及用于应用于患者的头部的热调节帽患者。

7. 发明申请

WO2005110228A1 CAM-ACTUATED MEDICAL PUNCTURING DEVICE AND METHOD 审中-公开
标题翻译： CAM致动医疗器械及方法
公开(公告)号：WO2005110228A1
公开(公告)日：2005-11-24
申请号：PCT/US2005/015859
申请日：2005-05-05
申请人： BECTON, DICKINSON AND COMPANY , DiCESARE, Paul , RADZIUNAS, Jeffrey , BATTLES, Christopher
发明人： DiCESARE, Paul , RADZIUNAS, Jeffrey , BATTLES, Christopher
IPC分类号： A61B5/15
CPC分类号： A61B5/1411 , A61B5/150022 , A61B5/150259 , A61B5/150412 , A61B5/150442 , A61B5/150503 , A61B5/150564 , A61B5/150618 , A61B5/150717 , A61B5/150832 , A61B5/150885 , A61B5/15111 , A61B5/15117 , A61B5/1513 , A61B5/15142 , A61B5/15144 , A61B5/15186
摘要： The medical puncturing device includes a housing (12), a shield (13), and a skin puncturing assembly disposed within the housing. The shield is axially movable in the housing. The skin puncturing assembly includes a movable carrier and a skin puncturing element mounted to the carrier. A distal end of the skin puncturing element is adapted for puncturing the skin of a patient. The carrier is movable from a retracted position wherein the skin puncturing element is disposed within the shield to a puncturing position wherein the distal end of the skin puncturing element is exposed. The carrier is maintained in the retracted position by engagement of flexure members or a retaining tab with the carrier. A drive spring is provided to move the carrier from the retracted position to the puncturing position. A retraction spring is provided to return the carrier and skin puncturing element into the housing.
摘要翻译：医疗穿刺装置包括壳体（12），护罩（13）和设置在壳体内的皮肤穿刺组件。屏蔽件可在壳体中轴向移动。皮肤穿刺组件包括可移动的载体和安装到载体的皮肤穿刺元件。皮肤穿刺元件的远端适于穿刺患者的皮肤。承载件可以从缩回位置移动，其中，皮肤穿刺元件设置在护罩内，到穿刺位置，其中皮肤穿刺元件的远端被暴露。承载件通过弯曲构件或保持翼片与载体的接合而保持在缩回位置。提供驱动弹簧以将托架从缩回位置移动到穿刺位置。提供缩回弹簧以将托架和皮肤穿刺元件返回到壳体中。

8. 发明申请

WO2005110226A1 ROTARY-ACTUATED MEDICAL PUNCTURING DEVICE 审中-公开
标题翻译：旋转式医疗器械
公开(公告)号：WO2005110226A1
公开(公告)日：2005-11-24
申请号：PCT/US2005/015578
申请日：2005-05-04
申请人： BECTON, DICKINSON AND COMPANY , DICESARE, Paul , RADZIUNAS, Jeffrey , BATTLES, Christopher
发明人： DICESARE, Paul , RADZIUNAS, Jeffrey , BATTLES, Christopher
IPC分类号： A61B5/15
CPC分类号： A61B5/150832 , A61B5/150022 , A61B5/150259 , A61B5/150412 , A61B5/150442 , A61B5/150503 , A61B5/150564 , A61B5/150618 , A61B5/150717 , A61B5/150885 , A61B5/15111 , A61B5/15117 , A61B5/1513 , A61B5/15144 , Y10T29/49826
摘要： The medical puncturing device includes an actuator, a shield, and a skin puncturing assembly. The actuator and shield are movable relative to one another. The skin- puncturing assembly includes a carrier and a skin-puncturing element. A distal end of the skin puncturing element is adapted for puncturing the skin of a patient. The carrier is movable from a retracted position wherein the distal end of the skin-puncturing element is disposed within the shield to a puncturing position wherein the distal end of the skin-puncturing element is exposed to puncture the skin of a patient. The carrier is maintained in the retracted position by interference engagement between the carrier and shield. A drive spring is provided to move the carrier from the retracted to puncturing positions. A retraction spring is provided to return the carrier to a position wherein the shield encompasses the skin puncturing element.
摘要翻译：医疗穿刺装置包括致动器，护罩和皮肤穿刺组件。致动器和屏蔽件可相对于彼此移动。皮肤穿刺组件包括载体和皮肤穿刺元件。皮肤穿刺元件的远端适于穿刺患者的皮肤。承载件可以从缩回位置移动，其中皮肤穿刺元件的远端设置在护罩内到穿刺位置，其中皮肤穿刺元件的远端暴露以刺穿患者的皮肤。载体通过载体和屏蔽之间的干涉接合而保持在缩回位置。提供驱动弹簧以将托架从缩回位置移动到穿刺位置。提供缩回弹簧以将托架返回到其中护罩包围皮肤穿刺元件的位置。

9. 发明申请

WO2010036227A1 ENDOSCOPIC SUTURING DEVICE 审中-公开
标题翻译：内窥镜装置
公开(公告)号：WO2010036227A1
公开(公告)日：2010-04-01
申请号：PCT/US2008/011244
申请日：2008-09-29
申请人： C R . BARD, INC . , DICESARE, Paul C. , RADZIUNAS, Jeffrey P.
发明人： DICESARE, Paul C. , RADZIUNAS, Jeffrey P.
IPC分类号： A61B17/04
CPC分类号： A61B17/0469
摘要： An endoscopic suturing device that can be employed to suture tissue using endoscopic techniques to place one or more stitches in tissue during a single intubation of an endoscope. The suturing device may include a suturing capsule with a suction chamber that is configured to capture tissue that is to be sutured. A needle is movable along a pathway across the suction chamber to penetrate and place stitches in the captured tissue. A catch is located distal to the suction chamber to receive and retain the suture during a stitching sequence. The catch may be movable along the needle pathway and configured to release the suture when the catch moves a predetermined distance along the pathway. The catch may be configured so that a predetermined amount of force is required to move the catch the predetermined distance required to release the suture.
摘要翻译：一种内窥镜缝合装置，其可用于使用内窥镜技术缝合组织，以在内窥镜的单次插管期间将一个或多个针迹放置在组织中。缝合装置可以包括具有吸引腔的缝合胶囊，该吸引腔被构造成捕获要被缝合的组织。针可以沿着穿过抽吸室的路径移动以穿过并将缝合放置在所捕获的组织中。捕获器位于吸入室的远侧以在缝合序列期间接收和保持缝合线。捕获器可以沿着针通道移动并且构造成当捕捉器沿着路径移动预定距离时释放缝合线。卡扣可以被构造成使得需要预定量的力来将卡扣移动以释放缝合线所需的预定距离。

10. 发明申请

WO2007136631A3 SUTURE LOCK FASTENING DEVICE 审中-公开
公开(公告)号：WO2007136631A3
公开(公告)日：2007-11-29
申请号：PCT/US2007/011671
申请日：2007-05-16
申请人： C.R.BARD, INC. , PAGE, Edward, C. , GUTELIUS, Patrick , FERREIRA, Danial , RADZIUNAS, Jeffrey , DICESARE, Paul
发明人： PAGE, Edward, C. , GUTELIUS, Patrick , FERREIRA, Danial , RADZIUNAS, Jeffrey , DICESARE, Paul
IPC分类号： A61B17/04
摘要： A suture lock fastening device to cinch a suture in a suture lock, cut the suture end, and deploy the suture lock in response to a single movement of a user. The fastening device includes a fastening head with a retainer that is configured to hold a suture lock in the fastening head. To release the suture lock from the fastening head, the retainer is irreversibly deformed. The fastening device may include an axially movable cutter with a cutting edge to sever the ends of the suture close to the suture lock. A threading device may be preloaded into the fastening device to facilitate threading the suture through the fastening device.

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