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1. 发明申请

WO2009089296A3 ANIMAL MANAGEMENT 审中-公开
标题翻译：动物管理
公开(公告)号：WO2009089296A3
公开(公告)日：2009-09-17
申请号：PCT/US2009030353
申请日：2009-01-07
申请人： METAMORPHIX INC , CARGILL INC , BUENFIL MILTON ALEJANDRO GOROC , THEUNINCK DUANE , ALLEN TODD RAYMOND , LANGFORD LARRY , DENISE SUE K , ROSENFELD DAVID , HOLM TOM , FANTIN DENNIS
发明人： BUENFIL MILTON ALEJANDRO GOROCICA , THEUNINCK DUANE , ALLEN TODD RAYMOND , LANGFORD LARRY , DENISE SUE K , ROSENFELD DAVID , HOLM TOM , FANTIN DENNIS
IPC分类号： A01K67/027 , C12Q1/68
CPC分类号： A01K67/027
摘要： Methods for managing animals can involve identifying a trait by analyzing a biological sample and determining a physical characteristic of a bovine subject using imaging. A method can include obtaining a targeted trait genetic value and determining a targeted trait value for a bovine subject using imaging. A method can include obtaining genetic information determined by identifying, in a biological sample from the first bovine subject, at least one single nucleotide polymorphism (SNP). An animal can be managed based on information that has been identified and/or obtained.
摘要翻译：用于管理动物的方法可以涉及通过分析生物样品来识别性状，并使用成像确定牛对象的物理特性。一种方法可以包括获得目标性状遗传值，并使用成像确定牛对象的目标性状值。一种方法可以包括获得通过在来自第一牛受试者的生物样品中鉴定至少一个单核苷酸多态性（SNP）而确定的遗传信息。可以基于已经识别和/或获得的信息来管理动物。

2. 发明申请

WO2004061124A3 COMPOSITIONS, METHODS, AND SYSTEMS FOR INFERRING BOVINE BREED 审中-公开
公开(公告)号：WO2004061124A3
公开(公告)日：2004-07-22
申请号：PCT/US2003/041761
申请日：2003-12-31
申请人： MMI GENOMICS, INC. , DeNISE, Sue, K. , CHARTERIS, Paul , ROSENFELD, David , HOLM, Tom , BATES, Stephen
发明人： DeNISE, Sue, K. , CHARTERIS, Paul , ROSENFELD, David , HOLM, Tom , BATES, Stephen
IPC分类号： C12Q1/68 , C12P19/34
摘要： Provided herein are methods to discover and use single nucleotide polymorphisms (SNP) for identifying breed, or line and breed, or line composition of a bovine subject. The present invention further provides specific nucleic acid sequences, SNPs, and SNP patterns that can be used for identifying breed or breed combinations for Angus, Holstein, Limousin, Brahman, Hereford, Simmental, Gelbvieh, Charolais and Beefmaster breeds. These patterns can be utilized to manage animals in a feedlot to obtain optimum performance based on known characteristics of specific breeds and identify animals for breeding in selection programs. In another aspect, these patterns can be used to ensure labeling on breed specific branded products.

3. 发明申请

WO2005040400A3 METHODS AND SYSTEMS FOR INFERRING TRAITS TO MANAGE NON-BEEF LIVESTOCK 审中-公开
标题翻译：感染非营养食品的方法和系统
公开(公告)号：WO2005040400A3
公开(公告)日：2008-03-20
申请号：PCT/US2004035274
申请日：2004-10-22
申请人： MMI GENOMICS INC , DENISE SUE K , ROSENFELD DAVID , KERR RICHARD , BATES STEPHEN , HOLM TOM
发明人： DENISE SUE K , ROSENFELD DAVID , KERR RICHARD , BATES STEPHEN , HOLM TOM
IPC分类号： C12Q1/68 , C12P19/34 , C12Q20060101
CPC分类号： C12Q1/6827
摘要： Methods and systems are provided for managing non-beef livestock subjects in order to maximize their individual potential performance and the value of a product from the non-beef livestock subjects, and to maximize profits obtained in marketing the . non-beef livestock subjects. The methods and systems draw an inference of a trait of a non-beef livestock subject by determining the nucleotide occurrence of at least one non-beef livestock SNP that is determined to be associated with the trait. The inference is used in methods of the present invention to establish the economic value of a non-beef livestock subject, to improve profits related to selling beef from a non-beef livestock subject; to manage non-beef livestock subjects, to sort non-beef livestock subjects; to improve the genetics of a non-beef livestock population by selecting and breeding of non-beef livestock subjects, to clone a non-beef livestock subject with a specific trait, to track meat or another commercial product of a non-beef livestock subject; and to diagnose a health condition of a non-beef livestock subject. Certain embodiments of the present invention provide methods, systems, and kits are directed to inferences of a trait related to milk or a dairy product in a livestock subject.
摘要翻译：提供方法和系统，用于管理非牛类牲畜科目，以最大限度地发挥其非牛肉牲畜品种的潜在性能和价值，并最大限度地利用营销中获得的利润。非牛肉家畜。方法和系统通过确定确定与性状相关联的至少一种非牛肉牲畜SNP的核苷酸发生来推断非牛肉家畜受试者的性状。本发明的方法用于确定非牛肉主体的经济价值，提高从非牛肉牲畜中销售牛肉的利润; 管理非牛肉牲畜，对非牛肉牲畜进行分类; 通过选择和培育非牛类牲畜，通过选择具有特殊性状的非牛肉牲畜来追踪非牛肉牲畜的肉类或其他商品，改善非牛类牲畜群体的遗传学; 并诊断非牛肉牲畜的健康状况。提供方法，系统和试剂盒的本发明的某些实施方案涉及与家畜受试者中的牛奶或乳制品相关的性状的推论。

4. 发明申请

WO2006029256A2 COMPOSITIONS, METHODS, AND SYSTEMS FOR DETERMINING BOVINE PARENTAGE AND IDENTITY 审中-公开
标题翻译：组合物，方法和系统，用于确定牛肉中的父母和身份
公开(公告)号：WO2006029256A2
公开(公告)日：2006-03-16
申请号：PCT/US2005/031959
申请日：2005-09-07
申请人： MMI GENOMICS, INC. , ROSENFELD, David , KERR, Richard , DENISE, Sue, K.
发明人： ROSENFELD, David , KERR, Richard , DENISE, Sue, K.
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6876 , C12Q1/6881 , C12Q2600/156 , C12Q2600/16
摘要： Provided herein are methods to discover and use single nucleotide polymorphisms (SNP) for identifying parentage or identity of a bovine subject. The present invention further provides specific nucleic acid sequences, SNPs, and SNP patterns that can be used for identifying parentage of various breeds of cattle including Angus, Holstein, Limousin, Brahman, Hereford, Simmental, Gelbvieh, Charolais and Beefmaster breeds.
摘要翻译：本文提供了发现和使用单核苷酸多态性（SNP）来鉴定牛受试者的亲本或身份的方法。本发明还提供了可用于鉴定包括Angus，Holstein，Limousin，Brahman，Hereford，Simmental，Gelbvieh，Charolais和Beefmaster品种的各种牛品种的亲本的特异性核酸序列，SNP和SNP模式。

5. 发明申请

WO2004063390A3 COMPOSITIONS AND METHODS FOR DETERMINING CANINE GENDER 审中-公开
标题翻译：用于确定罐头性别的组成和方法
公开(公告)号：WO2004063390A3
公开(公告)日：2005-05-19
申请号：PCT/US2004000523
申请日：2004-01-09
申请人： METAMORPHIX INC , FERRIE BONITA J M , JOHNSTON ERIC V , DENISE SUE K
发明人： FERRIE BONITA J M , JOHNSTON ERIC V , DENISE SUE K
IPC分类号： C07H21/04 , C12Q20060101 , C12Q1/68
CPC分类号： C12Q1/6888 , C12Q2600/156 , C12Q2600/16
摘要： The present invention provides methods to determine gender of a canine subject, that include contacting a nucleic acid sample from the canine subject with at least one probe or primer specific for canine amelogenin, and using the binding of the at least one probe or primer to detect a difference between the canine amelogenin gene on the Y chromosome and the canine amelogenin gene on the X chromosome, thereby determining gender of the canine subject. In certain aspects, gender of the canine subject is determined by contacting the nucleic acid sample with a primer pair that generate different sized amplification products depending on whether an X chromosome or a Y chromosome copy of the canine amelogenin gene is amplified. In certain aspects and embodiments disclosed herein, in addition to detecting binding of at least one probe or primer to a canine amelogenin gene, methods of the present invention include detecting binding of at least one probe or primer to a canine microsatellite locus, thus providing a genotyping and gender determination assay.
摘要翻译：本发明提供了确定犬科目的性别的方法，其包括使来自犬科目的核酸样品与至少一种针对犬类牙釉蛋白特异性的探针或引物接触，并使用所述至少一种探针或引物的结合来检测 Y染色体上的犬牙釉蛋白基因与X染色体上的犬牙釉蛋白基因之间的差异，从而确定犬科目的性别。在某些方面，通过使核酸样品与产生不同大小的扩增产物的引物对接触来确定犬受试者的性别，这取决于是否扩增了犬牙釉蛋白基因的X染色体或Y染色体拷贝。在本文公开的某些方面和实施方案中，除了检测至少一种探针或引物与犬牙釉蛋白基因的结合之外，本发明的方法包括检测至少一种探针或引物与犬微卫星位点的结合，从而提供基因分型和性别确定测定。

6. 发明申请

WO2005038553A3 DEVICE AND METHOD FOR ANIMAL TRACKING 审中-公开
公开(公告)号：WO2005038553A3
公开(公告)日：2005-04-28
申请号：PCT/US2004/027900
申请日：2004-08-27
申请人： MMI GENOMICS, INC. , FANTIN, Dennis , BATES, Steven , FEUZ, Bridger , DENISE, Sue, K. , HOLM, Tom
发明人： FANTIN, Dennis , BATES, Steven , FEUZ, Bridger , DENISE, Sue, K. , HOLM, Tom
IPC分类号： A01K29/00
摘要： Devices and method for tracking animals. More particularly, embodiments of the present invention provide a method of tracking an animal that includes assigning an animal identification (110) to a first animal, collecting a biological sample from the first animal and associating the first animal with each premises at which the first animal is located. The invention further provides an identification device (100) that includes a tag portion (102) and a sample portion (104). The tag portion can be configured to be attached to animal in any method known in the art. The sample portion can be detachably coupled to the tag portion and can include a biological collector (208) that can collect a biological sample from the animal.

7. 发明申请

WO2006029256A8 COMPOSITIONS, METHODS, AND SYSTEMS FOR DETERMINING BOVINE PARENTAGE AND IDENTITY 审中-公开
标题翻译：用于确定牛皮癣分泌和鉴定的组合物，方法和系统
公开(公告)号：WO2006029256A8
公开(公告)日：2009-07-16
申请号：PCT/US2005031959
申请日：2005-09-07
申请人： MMI GENOMICS INC , ROSENFELD DAVID , KERR RICHARD , DENISE SUE K
发明人： ROSENFELD DAVID , KERR RICHARD , DENISE SUE K
IPC分类号： C12Q1/68 , C07H21/02 , C07H21/04 , C12P19/34
CPC分类号： C12Q1/6876 , C12Q1/6881 , C12Q2600/156 , C12Q2600/16
摘要： Provided herein are methods to discover and use single nucleotide polymorphisms (SNP) for identifying parentage or identity of a bovine subject. The present invention further provides specific nucleic acid sequences, SNPs, and SNP patterns that can be used for identifying parentage of various breeds of cattle including Angus, Holstein, Limousin, Brahman, Hereford, Simmental, Gelbvieh, Charolais and Beefmaster breeds.
摘要翻译：本文提供了发现和使用单核苷酸多态性（SNP）以鉴定牛受试者的亲本或身份的方法。本发明进一步提供了可用于鉴定各种牛品种（包括安格斯，荷斯坦，利木赞，婆罗门，赫里福德，西门塔尔，盖尔布维，夏洛来牛和比夫马斯特品种）亲本的特定核酸序列，SNP和SNP模式。

8. 发明申请

WO2006029256A3 COMPOSITIONS, METHODS, AND SYSTEMS FOR DETERMINING BOVINE PARENTAGE AND IDENTITY 审中-公开
标题翻译：组合物，方法和系统，用于确定牛肉中的父母和身份
公开(公告)号：WO2006029256A3
公开(公告)日：2009-06-11
申请号：PCT/US2005031959
申请日：2005-09-07
申请人： MMI GENOMICS INC , ROSENFELD DAVID , KERR RICHARD , DENISE SUE K
发明人： ROSENFELD DAVID , KERR RICHARD , DENISE SUE K
IPC分类号： C12Q1/68 , C07H21/02 , C07H21/04 , C12P19/34
CPC分类号： C12Q1/6876 , C12Q1/6881 , C12Q2600/156 , C12Q2600/16
摘要： Provided herein are methods to discover and use single nucleotide polymorphisms (SNP) for identifying parentage or identity of a bovine subject. The present invention further provides specific nucleic acid sequences, SNPs, and SNP patterns that can be used for identifying parentage of various breeds of cattle including Angus, Holstein, Limousin, Brahman, Hereford, Simmental, Gelbvieh, Charolais and Beefmaster breeds.
摘要翻译：本文提供了发现和使用单核苷酸多态性（SNP）来鉴定牛受试者的亲本或身份的方法。本发明还提供了可用于鉴定包括Angus，Holstein，Limousin，Brahman，Hereford，Simmental，Gelbvieh，Charolais和Beefmaster品种的各种牛品种的亲本的特异性核酸序列，SNP和SNP模式。

9. 发明申请

WO2005052133A3 METHOD AND MARKERS FOR DETERMINING THE GENOTYPE OF HORNED/POLLED CATTLE 审中-公开
标题翻译：方法和标记用于确定被感染/感染的CATTLE的基因组
公开(公告)号：WO2005052133A3
公开(公告)日：2006-03-09
申请号：PCT/US2004039802
申请日：2004-11-23
申请人： MMI GENOMICS INC , DENISE SUE K , OBERG EMILY , FERRIE BONITA , ROSENFELD DAVID , CHEVALIER TOM , KERR RICHARD , HUTTON MICHELLE
发明人： DENISE SUE K , OBERG EMILY , FERRIE BONITA , ROSENFELD DAVID , CHEVALIER TOM , KERR RICHARD , HUTTON MICHELLE
IPC分类号： C12Q1/68 , C12N20060101 , C12N15/10 , C12N15/11 , C12N15/12 , G06F19/18 , G06F19/24
CPC分类号： C12Q1/6876 , C12Q2600/124 , C12Q2600/156 , C12Q2600/172 , G06F19/18 , G06F19/24
摘要： Provided herein are methods to discover and use single nucleotide polymorphisms (SNP) for determining the genotype of a horner/polled ruminant subject. The present invention further provides specific nucleic acid sequences, SNPs, and SNP patterns that can be used for determining the genotype of a horned/polled ruminant subject.
摘要翻译：本文提供了发现和使用单核苷酸多态性（SNP）来确定水平/轮询的反刍动物受试者的基因型的方法。本发明还提供可用于确定角/反向反刍动物受试者的基因型的特异性核酸序列，SNP和SNP模式。

10. 发明申请

WO2005052133A2 METHOD AND MARKERS FOR DETERMINING THE GENOTYPE OF HORNED/POLLED CATTLE 审中-公开
标题翻译：方法和标记用于确定被感染/感染的CATTLE的基因组
公开(公告)号：WO2005052133A2
公开(公告)日：2005-06-09
申请号：PCT/US2004/039802
申请日：2004-11-23
申请人： MMI GENOMICS, INC. , DENISE, Sue, K. , OBERG, Emily , FERRIE, Bonita , ROSENFELD, David , CHEVALIER, Tom , KERR, Richard , HUTTON, Michelle
发明人： DENISE, Sue, K. , OBERG, Emily , FERRIE, Bonita , ROSENFELD, David , CHEVALIER, Tom , KERR, Richard , HUTTON, Michelle
IPC分类号： C12N
CPC分类号： C12Q1/6876 , C12Q2600/124 , C12Q2600/156 , C12Q2600/172 , G06F19/18 , G06F19/24
摘要： Provided herein are methods to discover and use single nucleotide polymorphisms (SNP) for determining the genotype of a horner/polled ruminant subject. The present invention further provides specific nucleic acid sequences, SNPs, and SNP patterns that can be used for determining the genotype of a horned/polled ruminant subject.
摘要翻译：本文提供了发现和使用单核苷酸多态性（SNP）来确定水平/轮询的反刍动物受试者的基因型的方法。本发明还提供可用于确定角/反向反刍动物受试者的基因型的特异性核酸序列，SNP和SNP模式。

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