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    • 4. 发明申请
    • CATHETER FOR UNIFORM DELIVERY OF MEDICATION
    • 用于统一药物递送的导管
    • WO2004101052A2
    • 2004-11-25
    • PCT/US2004014664
    • 2004-05-11
    • I FLOW CORPDENIEGA JOSE CASTILLOMASSENGALE ROGERRAKE KENNETH WDAL PORTO JAMES
    • DENIEGA JOSE CASTILLOMASSENGALE ROGERRAKE KENNETH WDAL PORTO JAMES
    • A61F2/958A61M25/00A61M29/00
    • A61M25/003A61M25/0032A61M25/007A61M25/10A61M29/00A61M2025/0036A61M2025/0057A61M2025/105
    • A catheter (250, 272) is provided for uniform distribution of fluid medication within an anatomical region. One embodiment of the catheter (272) is comprised of an elongated, proximal tube (282) defining a lumen (283) and an elongated, distal tube (280) having a closed end (284). The distal tube (280) is constructed from a bio-absorbable material and also defines a lumen (281), which communicates with the lumen (283) of the proximal tube (282). Another embodiment of the catheter (250) is comprised of an elongate tubular catheter body (254) defining a lumen (268). A distal end (262) of the lumen is closed and a portion of the catheter body (254) includes a plurality of openings (266) thereby defining an infusion section of the catheter (250). A tubular sheath (252) is constructed from a porous material and is positioned over the infusion section. The tubular sheath (252) extends at least a length of the infusion section. The tubular sheath (252) and the catheter body (254) are configured such that fluid within the lumen (268) must pass through the tubular sheath (252) to exit the catheter (250).
    • 提供导管(250,272),用于在解剖区域内均匀分布流体药物。 导管(272)的一个实施例包括限定内腔(283)的细长近端管(282)和具有闭合端(284)的细长远侧管(280)。 远端管(280)由生物可吸收材料构成,并且还限定与近端管(282)的内腔(283)连通的管腔(281)。 导管(250)的另一实施例由限定内腔(268)的细长管状导管主体(254)组成。 管腔的远端(262)是封闭的并且导管主体(254)的一部分包括多个开口(266),由此限定了导管(250)的输注部分。 管状护套(252)由多孔材料制成并位于输注部分上方。 管状护套(252)延伸至少一段输注部分。 管状护套(252)和导管主体(254)被构造成使得腔(268)内的流体必须通过管状护套(252)以离开导管(250)。
    • 5. 发明申请
    • CATHETER FOR UNIFORM DELIVERY OF MEDICATION
    • 统一送达药物的导管
    • WO0105210A3
    • 2001-07-19
    • PCT/US0019746
    • 2000-07-19
    • I FLOW CORPDENIEGA JOSE CASTILLOMASSENGALE ROGERRAKE KENNETH W
    • DENIEGA JOSE CASTILLOMASSENGALE ROGERRAKE KENNETH W
    • A61M25/00A61M25/16
    • A61M25/0074A61M25/00A61M25/0023A61M25/0043A61M25/0068A61M25/0069A61M25/007A61M2025/0037A61M2025/0039A61M2025/0057A61M2025/0073
    • The present invention provides a catheter for the delivery of fluid medication across an anatomical region. In accordance with one embodiment, the catheter comprises an elongated tube with a plurality of exit holes along an infusion section of the catheter, and an elongated flexible porous member residing within the tube and forming an annular space between the tube and the member. In accordance with other embodiments, the catheter includes a tube having a plurality of exit holes in a side wall of the tube. The exit holes may combine to form a flow-restricting orifice of the catheter. Advantageously, fluid within the catheter flows through all of the exit holes, resulting in uniform distribution of fluid within an anatomical region. In one particular embodiment, the catheter comprises a tube having elongated exit slots therein. In accordance with other embodiments, the catheter includes an elongated tubular member made of a porous membrane. The porous membrane is configured so that a fluid introduced into an open end of the tubular member will flow through side walls of the tubular member at a substantially uniform rate along a length of the tubular member. In accordance with other embodiments, the catheter includes an elongated "weeping" tubular coil spring attached to an end of, or enclosed within, a tube. Fluid within the spring and greater than or equal to a threshold pressure advantageously flows radially outward between the spring coils. Advantageously, the fluid is dispensed substantially uniformly throughout a length of the spring.
    • 本发明提供了用于输送流体药物穿过解剖区域的导管。 根据一个实施例,所述导管包括细长管,所述细长管具有沿所述导管的输注部分的多个出口孔以及位于所述管内并在所述管和所述构件之间形成环形空间的细长柔性多孔构件。 根据其他实施例,导管包括在管的侧壁中具有多个出口孔的管。 出口孔可以结合以形成导管的流量限制孔口。 有利地,导管内的流体流过所有的出口孔,导致在解剖区域内流体的均匀分布。 在一个特定实施例中,导管包括其中具有细长出口槽的管。 根据其他实施例,导管包括由多孔膜制成的细长管状构件。 多孔膜构造成使得引入管状构件的开口端的流体将沿管状构件的长度以基本均匀的速率流过管状构件的侧壁。 根据其他实施例,导管包括附接到管的一端或封闭在管内的细长的“哭泣”管状螺旋弹簧。 弹簧内的流体并且大于或等于阈值压力有利地在弹簧圈之间径向向外流动。 有利的是,流体在弹簧的整个长度上基本均匀地分配。