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1. 发明申请

WO2009155577A3 BONE SCREW PURCHASE AUGMENTATION IMPLANTS, SYSTEMS AND TECHNIQUES 审中-公开
公开(公告)号：WO2009155577A3
公开(公告)日：2009-12-23
申请号：PCT/US2009/048055
申请日：2009-06-19
申请人： SYNTHES USA, LLC , SYNTHES GMBH , KALE, Shreedhar , CHIEN, Dennis , DELURIO, Robert , COMPTON, Curtis
发明人： KALE, Shreedhar , CHIEN, Dennis , DELURIO, Robert , COMPTON, Curtis
IPC分类号： A61B17/68 , F16B13/00
摘要： The present invention provides a system, device, instruments and methods for improving the holding strength and purchase of a screw in the body, preferably a screw in bone, preferably a vertebral bone. In one embodiment an allograft tissue form configured for placement between a preformed hole preferably through a pedicle and into the interior of a vertebral body is provided to receive a pedicle screw that is to be introduced through the allograft tissue form. Embodiments include monolithic allograft tissue forms, multi-piece allograft tissue forms, distally expandable portions, partially and fully demineralized portions, and flexible connecting portions. Advantages of the allograft tissue forms of the present invention include improved pedicle screw blackout strength. Methods for making and instruments and techniques for inserting the augmentation device, system and pedicle screws are also disclosed.

2. 发明申请

WO2009006432A3 FLEXIBLE CHAIN IMPLANTS AND INSTRUMENTATION 审中-公开
标题翻译：柔性链植入物和仪器
公开(公告)号：WO2009006432A3
公开(公告)日：2009-06-25
申请号：PCT/US2008068836
申请日：2008-06-30
申请人： SYNTHES USA , SYNTHES GMBH , COMPTON CURTIS , CHIEN DENNIS , DELURIO ROBERT , MESSERLI DOMINIQUE
发明人： COMPTON CURTIS , CHIEN DENNIS , DELURIO ROBERT , MESSERLI DOMINIQUE
IPC分类号： A61B17/88 , A61B17/70
CPC分类号： A61F2/442 , A61B17/7094 , A61F2/28 , A61F2/4455 , A61F2/4611 , A61F2002/30281 , A61F2002/30289 , A61F2002/30387 , A61F2002/30403 , A61F2002/30471 , A61F2002/30472 , A61F2002/30476 , A61F2002/30504 , A61F2002/30594 , A61F2002/4415 , A61F2002/444 , A61F2002/4627 , A61F2220/0025 , A61F2220/0041 , A61F2220/0091 , A61F2230/0086 , A61F2230/0091 , A61F2310/00359
摘要： A flexible chain implant (10, 1000, 1100) for insertion into an interior volume of a vertebral body (602). The implant may be implanted in an insertion position for sliding through a cannula (1200, 606) and is flexible for packing into the interior volume in an implanted configuration. The implant randomly separates in the implanted configuration. The implant includes a top member (20) and a bottom member (30), wherein the top and bottom members are coupled to one another at a coupled portion (50). The top and bottom members preferably each include an inner surface such that the inner surfaces include a plurality of alternating projections (40, 42) and recesses (45, 47) so that the projections are received within the recesses in an insertion position. Alternatively, the implant may include a plurality of substantially non- flexible bodies (1010, 1110) and a plurality of substantially flexible links (1020, 1120) interconnecting the bodies. The non-flexible bodies include a plurality of facets (1030) and/or abutment surfaces (1118).
摘要翻译：一种用于插入到椎体（602）的内部体积中的柔性链植入体（10,1000,1100）。植入物可以植入插入位置以滑动通过插管（1200,606），并且是柔性的，以便以植入构型填充到内部容积中。植入物在植入构型中随机分离。植入物包括顶部构件（20）和底部构件（30），其中顶部构件和底部构件在联接部分（50）处彼此联接。顶部和底部构件优选地各自包括内表面，使得内表面包括多个交替的突起（40,42）和凹部（45,47），使得突起在插入位置中容纳在凹部内。或者，植入物可以包括多个基本上非柔性的主体（1010,1110）和互连这些主体的多个基本上柔性的连接件（1020,1120）。非柔性体包括多个小面（1030）和/或邻接表面（1118）。

3. 发明申请

WO2005097004A3 ALLOGRAFT IMPLANT 审中-公开
标题翻译： ALLOGRAFT植物
公开(公告)号：WO2005097004A3
公开(公告)日：2007-04-26
申请号：PCT/US2005010255
申请日：2005-03-28
申请人： SYNTHES USA , RANDALL BRANDON L , GOODWIN ROGER D , MESSERLI DOMINIQUE , MYER JACQUELINE , DELURIO ROBERT J , BOYER MICHAEL L II , ANGELUCCI CHRISTOPHER M
发明人： RANDALL BRANDON L , GOODWIN ROGER D , MESSERLI DOMINIQUE , MYER JACQUELINE , DELURIO ROBERT J , BOYER MICHAEL L II , ANGELUCCI CHRISTOPHER M
IPC分类号： A61F2/28 , A61B17/88 , A61B17/92 , A61F2/00 , A61F2/30 , A61F2/44 , A61F2/46
CPC分类号： A61F2/44 , A61F2/28 , A61F2/3094 , A61F2/4455 , A61F2/4611 , A61F2002/2835 , A61F2002/30057 , A61F2002/30266 , A61F2002/30383 , A61F2002/30387 , A61F2002/30492 , A61F2002/30507 , A61F2002/30571 , A61F2002/30604 , A61F2002/30617 , A61F2002/30782 , A61F2002/30795 , A61F2002/3082 , A61F2002/30843 , A61F2002/30904 , A61F2002/4622 , A61F2002/4628 , A61F2002/4629 , A61F2220/0025 , A61F2230/0082 , A61F2250/0097 , A61F2310/00359
摘要： An allogenic implant for use in intervertebral fusion is formed from one or more two pieces. The pieces are made from bone, and are joined together to form an implant having sufficient strength and stability to maintain a desired distance between first and second vertebrae in a spinal fusion procedure. The implant pieces may be formed of cortical bone and connected by dovetail joints, and at least one cortical bone pin may be provided to lock the pieces together and to add strength to the implant. Teeth are formed on the vertebra engaging surfaces of the implant prevent short-term slippage of the implant.
摘要翻译：用于椎间融合的同种异体植入物由一个或多个两片形成。这些片由骨制成，并且连接在一起以形成具有足够的强度和稳定性的植入物，以在脊柱融合程序中保持第一和第二椎骨之间的期望距离。植入物片可以由皮质骨形成并且通过燕尾关节连接，并且可以提供至少一个皮质骨针将锁定在一起并增加植入物的强度。牙齿形成在植入物的椎骨接合表面上，防止植入物的短期滑动。

4. 发明申请

WO2005097004A2 ALLOGRAFT IMPLANT 审中-公开
标题翻译： ALLOGRAFT植物
公开(公告)号：WO2005097004A2
公开(公告)日：2005-10-20
申请号：PCT/US2005/010255
申请日：2005-03-28
申请人： SYNTHES (U.S.A.) , RANDALL, Brandon, L. , GOODWIN, Roger, D. , MESSERLI, Dominique , MYER, Jacqueline , DELURIO, Robert, J. , BOYER, Michael, L., II , ANGELUCCI, Christopher, M.
发明人： RANDALL, Brandon, L. , GOODWIN, Roger, D. , MESSERLI, Dominique , MYER, Jacqueline , DELURIO, Robert, J. , BOYER, Michael, L., II , ANGELUCCI, Christopher, M.
IPC分类号： A61F2/44
CPC分类号： A61F2/44 , A61F2/28 , A61F2/3094 , A61F2/4455 , A61F2/4611 , A61F2002/2835 , A61F2002/30057 , A61F2002/30266 , A61F2002/30383 , A61F2002/30387 , A61F2002/30492 , A61F2002/30507 , A61F2002/30571 , A61F2002/30604 , A61F2002/30617 , A61F2002/30782 , A61F2002/30795 , A61F2002/3082 , A61F2002/30843 , A61F2002/30904 , A61F2002/4622 , A61F2002/4628 , A61F2002/4629 , A61F2220/0025 , A61F2230/0082 , A61F2250/0097 , A61F2310/00359
摘要： An allogenic implant for use in intervertebral fusion is formed from one or more two pieces. The pieces are made from bone, and are joined together to form an implant having sufficient strength and stability to maintain a desired distance between first and second vertebrae in a spinal fusion procedure. The implant pieces may be formed of cortical bone and connected by dovetail joints, and at least one cortical bone pin may be provided to lock the pieces together and to add strength to the implant. Teeth are formed on the vertebra engaging surfaces of the implant prevent short-term slippage of the implant.
摘要翻译：用于椎间融合的同种异体植入物由一个或多个两片形成。这些片由骨制成，并且连接在一起以形成具有足够强度和稳定性的植入物，以在脊柱融合程序中保持第一和第二椎骨之间的期望距离。植入物片可以由皮质骨形成并且通过燕尾接头连接，并且可以提供至少一个皮质骨针将锁定在一起并增加植入物的强度。牙齿形成在植入物的椎骨接合表面上，防止植入物的短期滑动。

5. 发明申请

WO2010025408A3 BONE-DERIVED INTERSPINOUS SPACER 审中-公开
公开(公告)号：WO2010025408A3
公开(公告)日：2010-03-04
申请号：PCT/US2009/055428
申请日：2009-08-28
申请人： SYNTHES USA, LLC , SYNTHES GMBH , ASCHMANN, Felix , COPPES, Justin , DELURIO, Robert , BARRALL, Benjamin , CHOW, David , ANGERT, Nicholas
发明人： ASCHMANN, Felix , COPPES, Justin , DELURIO, Robert , BARRALL, Benjamin , CHOW, David , ANGERT, Nicholas
IPC分类号： A61B17/70
摘要： An allograft interspinous spacer for implantation into an interspinous space located between spinous process of adjacent vertebrae. The spacer preferably includes a body, a core and a plurality of dep lovable retainers. The body may be operatively associated with the plurality of deployable retainers. In use, after the body has been inserted into the interspinous space, the plurality of retainers is deployed so that they prevent migration of the spacer. The core is preferably sized and configured to be inserted and/or moved into operatively engagement with the body to deploy the plurality of retainers.

6. 发明申请

WO2010025408A2 BONE-DERIVED INTERSPINOUS SPACER 审中-公开
标题翻译：骨衍生的间质间隔物
公开(公告)号：WO2010025408A2
公开(公告)日：2010-03-04
申请号：PCT/US2009055428
申请日：2009-08-28
申请人： SYNTHES USA LLC , SYNTHES GMBH , ASCHMANN FELIX , COPPES JUSTIN , DELURIO ROBERT , BARRALL BENJAMIN , CHOW DAVID , ANGERT NICHOLAS
发明人： ASCHMANN FELIX , COPPES JUSTIN , DELURIO ROBERT , BARRALL BENJAMIN , CHOW DAVID , ANGERT NICHOLAS
IPC分类号： A61B17/70
CPC分类号： A61B17/7065
摘要： An allograft interspinous spacer for implantation into an interspinous space located between spinous process of adjacent vertebrae. The spacer preferably includes a body, a core and a plurality of dep lovable retainers. The body may be operatively associated with the plurality of deployable retainers. In use, after the body has been inserted into the interspinous space, the plurality of retainers is deployed so that they prevent migration of the spacer. The core is preferably sized and configured to be inserted and/or moved into operatively engagement with the body to deploy the plurality of retainers.
摘要翻译：用于植入位于相邻椎骨的棘突之间的椎间间隙的同种异体移植椎间间隔物。间隔件优选地包括主体，芯体和多个可爱的保持器。主体可以与多个可展开保持器可操作地关联。在使用中，在身体插入椎间空间之后，多个保持器被展开以防止间隔物的移动。芯部的尺寸和构造优选地被设计成插入和/或移动成与本体可操作地接合以展开多个保持器。

7. 发明申请

WO2009006432A2 FLEXIBLE CHAIN IMPLANTS AND INSTRUMENTATION 审中-公开
标题翻译：柔性链植入物和仪器
公开(公告)号：WO2009006432A2
公开(公告)日：2009-01-08
申请号：PCT/US2008/068836
申请日：2008-06-30
申请人： SYNTHES (U.S.A.) , SYNTHES GMBH , COMPTON, Curtis , CHIEN, Dennis , DELURIO, Robert , MESSERLI, Dominique
发明人： COMPTON, Curtis , CHIEN, Dennis , DELURIO, Robert , MESSERLI, Dominique
IPC分类号： A61B17/88 , A61B17/70
CPC分类号： A61F2/442 , A61B17/7094 , A61F2/28 , A61F2/4455 , A61F2/4611 , A61F2002/30281 , A61F2002/30289 , A61F2002/30387 , A61F2002/30403 , A61F2002/30471 , A61F2002/30472 , A61F2002/30476 , A61F2002/30504 , A61F2002/30594 , A61F2002/4415 , A61F2002/444 , A61F2002/4627 , A61F2220/0025 , A61F2220/0041 , A61F2220/0091 , A61F2230/0086 , A61F2230/0091 , A61F2310/00359
摘要： A flexible chain implant for insertion into an interior volume of a vertebral body. The implant may be implanted in an insertion position for sliding through a cannula and is flexible for packing into the interior volume in an implanted configuration. The implant randomly separates in the implanted configuration. The implant includes a top member and a bottom member, wherein the top and bottom members are coupled to one another at a coupled portion. The top and bottom members preferably each include an inner surface such that the inner surfaces include a plurality of alternating projections and recesses so that the projections are received within the recesses in an insertion position. Alternatively, the implant may include a plurality of substantially non- flexible bodies and a plurality of substantially flexible links interconnecting the bodies. The non-flexible bodies include a plurality of facets and/or abutment surfaces.
摘要翻译：用于插入椎体内部体积的柔性链植入物。植入物可以植入插入位置以滑动通过插管，并且是柔性的，以植入构型包装到内部容积中。植入物在植入构型中随机分离。植入物包括顶部构件和底部构件，其中顶部构件和底部构件在联接部分处彼此联接。顶部和底部构件优选地各自包括内表面，使得内表面包括多个交替的突起和凹部，使得突起在插入位置中容纳在凹部内。或者，植入物可以包括多个基本上非弹性的主体和互连主体的多个基本上柔性的连杆。非柔性体包括多个面和/或邻接表面。

8. 发明申请

WO2009155577A2 BONE SCREW PURCHASE AUGMENTATION IMPLANTS, SYSTEMS AND TECHNIQUES 审中-公开
标题翻译：骨螺钉购买补充植入物，系统和技术
公开(公告)号：WO2009155577A2
公开(公告)日：2009-12-23
申请号：PCT/US2009048055
申请日：2009-06-19
申请人： SYNTHES USA LLC , SYNTHES GMBH , KALE SHREEDHAR , CHIEN DENNIS , DELURIO ROBERT , COMPTON CURTIS
发明人： KALE SHREEDHAR , CHIEN DENNIS , DELURIO ROBERT , COMPTON CURTIS
IPC分类号： A61B17/68 , F16B13/00
CPC分类号： A61B17/686 , F16B2013/009
摘要： The present invention provides a system, device, instruments and methods for improving the holding strength and purchase of a screw in the body, preferably a screw in bone, preferably a vertebral bone. In one embodiment an allograft tissue form configured for placement between a preformed hole preferably through a pedicle and into the interior of a vertebral body is provided to receive a pedicle screw that is to be introduced through the allograft tissue form. Embodiments include monolithic allograft tissue forms, multi-piece allograft tissue forms, distally expandable portions, partially and fully demineralized portions, and flexible connecting portions. Advantages of the allograft tissue forms of the present invention include improved pedicle screw blackout strength. Methods for making and instruments and techniques for inserting the augmentation device, system and pedicle screws are also disclosed.
摘要翻译：本发明提供了一种用于提高保持强度并购买本体中的螺钉的系统，装置，仪器和方法，优选地在骨头中的螺钉，优选地是椎骨。在一个实施例中，提供了构造成用于放置在优选穿过椎弓根的预成形孔并进入椎体内部的同种异体移植组织形式以接收待通过同种异体移植组织形式引入的椎弓根螺钉。实施方案包括整体同种异体移植组织形式，多片同种异体移植组织形式，远端可扩展部分，部分和完全脱矿质部分以及柔性连接部分。本发明的同种异体移植组织形式的优点包括改善的椎弓根螺钉停电强度。还公开了制造方法以及用于插入增大装置，系统和椎弓根螺钉的仪器和技术。

9. 发明申请

WO2007089905A3 INTERSPINOUS PROCESS SPACER 审中-公开
公开(公告)号：WO2007089905A3
公开(公告)日：2007-10-04
申请号：PCT/US2007002791
申请日：2007-01-31
申请人： SYNTHES USA , SYNTHES GMBH , JACKSON BENJAMIN L , CHOW DAVID , DELURIO ROBERT J
发明人： JACKSON BENJAMIN L , CHOW DAVID , DELURIO ROBERT J
IPC分类号： A61B17/70 , A61F2/44
CPC分类号： A61B17/7062 , A61B2017/0256
摘要： An interspinous process spacer (100) is generally rectangular and may have an upper face (106) that generally opposes a lower face (105), front and back sides (104,103) that generally oppose each other, an end side, and a nose (110) that generally opposes the end side. The spacer preferably has rounded edges between the upper face and the front, end, and back sides and between the lower face and the front, end, and back sides. The nose of the spacer is preferably asymmetrical and tapers integrally, distally, and inwardly from the first and second faces to form a generally pointed or rounded distal tip. A spacer may be inserted laterally into the interspinous space through a small, posterior midline incision, allowing the preservation of the supraspinous ligament.
摘要翻译：棘突间间隔物（100）通常是矩形的并且可以具有通常与下表面（105），通常彼此相对的前侧和后侧（104,103）相对的上表面（106），端面和鼻部 110）通常反对终端。间隔件优选地在上表面与前端，端部和后侧之间以及下表面与前端，端侧和后侧之间具有圆形边缘。间隔件的鼻部优选地是不对称的并且从第一和第二表面一体地，远端地和向内逐渐变细，以形成大致尖的或圆形的远侧末端。间隔物可以通过小的后中线切口横向插入椎间盘间隙，允许保留上棘韧带。

10. 发明申请

WO2007089905A2 INTERSPINOUS PROCESS SPACER 审中-公开
公开(公告)号：WO2007089905A2
公开(公告)日：2007-08-09
申请号：PCT/US2007/002791
申请日：2007-01-31
申请人： SYNTHES (U.S.A.) , SYNTHES GMBH , JACKSON, Benjamin, L. , CHOW, David , DELURIO, Robert, J.
发明人： JACKSON, Benjamin, L. , CHOW, David , DELURIO, Robert, J.
IPC分类号： A61F2/44
CPC分类号： A61B17/7062 , A61B2017/0256
摘要： An interspinous process spacer is generally rectangular and may have an upper face that generally opposes a lower face, front and back sides that generally oppose each other, an end side, and a nose that generally opposes the end side. The spacer preferably has rounded edges between the upper face and the front, end, and back sides and between the lower face and the front, end, and back sides. The nose of the spacer is preferably asymmetrical and tapers integrally, distally, and inwardly from the first and second faces to form a generally pointed or rounded distal tip. A spacer may be inserted laterally into the interspinous space through a small, posterior midline incision, allowing the preservation of the supraspinous ligament. One or more spacers may be placed between spinous processes of adjacent vertebrae, and result in distraction of the spinous processes which may limit extension of the spine. Implantation of an interspinous process may inhibit or prevent the narrowing of the spinal canal and neural foramen at the level of treatment, thereby relieving pain symptoms. Preservation of the supraspinous ligament may provide additional stability, for example by keeping the implant from migrating posteriorly.
摘要翻译：棘突间间隔件通常是矩形的，并且可以具有通常与通常彼此相对的下表面，前侧和后侧相对的上表面，端面和通常与端侧相对的鼻部。间隔件优选地在上表面与前端，端部和后侧之间以及下表面与前端，端侧和后侧之间具有圆形边缘。间隔件的鼻部优选地是不对称的并且从第一和第二表面一体地，远端地和向内逐渐变细，以形成大致尖的或圆形的远侧末端。间隔物可以通过小的后中线切口横向插入椎间盘间隙，允许保留上棘韧带。一个或多个间隔物可以放置在相邻椎骨的棘突之间，并且导致棘突的分散，这可能限制脊柱的延伸。棘突间植入可以抑制或预防治疗水平的椎管和神经孔的变窄，从而缓解疼痛症状。保留上棘韧带可以提供额外的稳定性，例如通过保持植入物向后移动。

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