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1. 发明申请

WO2021058624A1 DEVICE FOR ULTRA-HIGH DOSE RATE RADIATION TREATMENT 审中-公开
公开(公告)号：WO2021058624A1
公开(公告)日：2021-04-01
申请号：PCT/EP2020/076662
申请日：2020-09-24
申请人： CENTRE HOSPITALIER UNIVERSITAIRE VAUDOIS (C.H.U.V.) , CERN - EUROPEAN ORGANIZATION FOR NUCLEAR RESEARCH
发明人： BOURHIS, Jean François Marie , VOZENIN, Marie-Catherine Sophine , GERMOND, Jean-François , WUENSCH, Walter , STAPNES, Steinar , GRUDIEV, Alexej
IPC分类号： A61N5/10 , H05H9/04
摘要： The present relates to device for ultra-high dose rate radiation treatment to a patient, comprising : - a radiation source for providing a radiation beam, and - a linear accelerator for accelerating said radiation beam until a predetermined energy, and - a beam delivery module for delivery the accelerated radiation beam, The device is arranged for generating an accelerated radiation beam having a predetermined energy between about 50 MeV and about 250 MeV, to deliver rate radiation dose of at least 10 Gy, during an overall time less than about 200 ms in order to generate a radiation field for treating a target volume of at least about 30 cm3, with said ultra-high dose rate radiation dose and/or a target volume located at least about 5 cm deep in the tissue of the patient with said ultra-high dose rate radiation dose.

2. 发明申请

WO2013178315A1 CRYOGENIC COOLING PUMP AND METHOD 审中-公开
标题翻译：低温冷却泵和方法
公开(公告)号：WO2013178315A1
公开(公告)日：2013-12-05
申请号：PCT/EP2013/001303
申请日：2013-05-02
申请人： CERN - EUROPEAN ORGANIZATION FOR NUCLEAR RESEARCH
发明人： HAUG, Friedrich , SCHMID, Jonas
IPC分类号： F04B15/08 , F04B7/04
CPC分类号： F04B15/08 , F04B7/04 , F04B17/03 , F04B19/22 , F04B2015/081 , F04B2015/082
摘要： A pump (10) for circulating a cryogenic coolant, comprising: a cylinder housing (14); a piston (16) received in said cylinder housing (14) for reciprocating in said cylinder housing (14) between a first death center position (18) and a second death center position (20), said first death center position (18) and said second death center position (20) defining a compression chamber (22) therebetween; an outlet (34) for said compression chamber (22); and an inlet (36) formed in a wall (24) of said cylinder housing (14) at a position between said first death center position (18) and said second death center position (20); wherein said inlet (36) is adapted to establish a fluid connection between said compression chamber (22) and a coolant reservoir (40; 76).
摘要翻译：一种用于使低温冷却剂循环的泵（10），包括：气缸壳体（14）; 容纳在所述气缸壳体（14）中的活塞（16），用于在所述气缸壳体（14）中在第一死亡中心位置（18）和第二死亡中心位置（20）之间往复运动，所述第一死亡中心位置（18）和所述第二死亡中心位置（20）在其间限定压缩室（22）; 用于所述压缩室（22）的出口（34）; 以及在所述第一死亡中心位置（18）和所述第二死亡中心位置（20）之间的位置处形成在所述气缸壳体（14）的壁（24）中的入口（36）。其中所述入口（36）适于在所述压缩室（22）和冷却剂储存器（40; 76）之间建立流体连接。

3. 发明申请

WO2013029781A1 HIGH POWER HIGH FREQUENCY LOADS FOR ENERGY RECOVERY 审中-公开
标题翻译：用于能量回收的高功率高频负载
公开(公告)号：WO2013029781A1
公开(公告)日：2013-03-07
申请号：PCT/EP2012/003613
申请日：2012-08-28
申请人： CERN - EUROPEAN ORGANIZATION FOR NUCLEAR RESEARCH , FEDERMANN, Silke , CASPERS, Fritz , BETZ, Michael
发明人： FEDERMANN, Silke , CASPERS, Fritz , BETZ, Michael
IPC分类号： H01P1/26 , H01P1/28 , H01R13/00
CPC分类号： H01P1/264 , H01P1/262 , H01P1/266 , H01P1/28
摘要： A radio frequency load (100) for absorbing a radio frequency wave having a frequency in a predetermined frequency band and a wavelength λ comprises a waveguide (110;210) with a portion having an opening (112) for said radio frequency wave. In addition, the radio frequency load (100) comprises at least one metal rod (120) provided in said waveguide (110; 210), said at least one metal rod (120) having a length of one-half of said wavelength λ to damp said radio frequency wave.
摘要翻译：一种用于吸收具有预定频带中的频率和波长λ的射频波的射频负载（100）包括具有用于所述射频波的开口（112）的部分的波导（110; 210）。此外，射频负载（100）包括设置在所述波导（110; 210）中的至少一个金属杆（120），所述至少一个金属棒（120）具有所述波长λ的一半的长度以阻止所述射频。

4. 发明申请

WO2009127220A1 A METHOD OF MANUFACTURING A GAS ELECTRON MULTIPLIER 审中-公开
标题翻译：一种制造气体电子乘法器的方法
公开(公告)号：WO2009127220A1
公开(公告)日：2009-10-22
申请号：PCT/EP2008/002944
申请日：2008-04-14
申请人： CERN - EUROPEAN ORGANIZATION FOR NUCLEAR RESEARCH TECHNOLOGY TRANSFER GROUP , DE OLIVEIRA, Rui
发明人： DE OLIVEIRA, Rui
IPC分类号： H01J43/06 , G01N27/22
CPC分类号： H01J47/02
摘要： A method of manufacturing a gas electron multiplier is shown. The method comprises a step of preparing a blank sheet (28) comprised of an insulating sheet (12) with first and second metal layers (14, 16) on its surface, a first metal layer hole forming step in which the first metal layer is patterned by means of photolithography, such as to form holes (18) through the first metal layer, an insulating sheet hole forming step, in which the holes (18) formed in the first metal layer (14) are extended through the insulating layer (12) by etching from the first surface side only, and a second metal layer hole forming step, in which the holes (18) are extended through the second metal layer (16). In one embodiment, the second metal layer hole forming step is performed by electrochemical etching, such that the first metal layer (14) remains unaffected during etching of the second metal layer (16). In another embodiment, in the second metal layer hole forming step, the first and second metal layers (14, 16) are etched from the outside, thereby reducing the initial thicknesses of the first and second metal layers (14, 16) and the second metal layer (16) is simultaneously etched through the holes (18) in the first metal layer (14) and the insulating sheet (12), said etching being maintained until the holes (18) extend through the second metal layer, wherein said initial average thickness of the first and second metal layers (14, 16) is between 6.5 μm and 25 μm, preferably between 7.5 μm and 12 μm.
摘要翻译：示出了制造气体电子倍增器的方法。该方法包括在其表面上制备由绝缘片（12）构成的第一和第二金属层（14,16）的空白片（28）的步骤，其中第一金属层形成步骤通过光刻法图案化，例如通过第一金属层形成孔（18），绝缘片孔形成步骤，其中形成在第一金属层（14）中的孔（18）延伸穿过绝缘层（ 12），以及第二金属层孔形成工序，其中孔（18）延伸穿过第二金属层（16）。在一个实施例中，第二金属层孔形成步骤通过电化学蚀刻进行，使得第一金属层（14）在蚀刻第二金属层（16）期间保持不受影响。在另一个实施例中，在第二金属层孔形成步骤中，从外部蚀刻第一和第二金属层（14,16），由此减小第一和第二金属层（14,16）的初始厚度，而第二金属层通过第一金属层（14）和绝缘片（12）中的孔（18）同时蚀刻金属层（16），所述蚀刻保持直到孔（18）延伸穿过第二金属层，其中所述初始第一和第二金属层（14,16）的平均厚度在6.5μm和25μm之间，优选在7.5μm和12μm之间。

5. 发明申请

WO2021260028A1 DEVICE FOR PROVIDING A RADIATION TREATMENT 审中-公开
公开(公告)号：WO2021260028A1
公开(公告)日：2021-12-30
申请号：PCT/EP2021/067189
申请日：2021-06-23
申请人： CENTRE HOSPITALIER UNIVERSITAIRE VAUDOIS (C.H.U.V.) , CERN - EUROPEAN ORGANIZATION FOR NUCLEAR RESEARCH
发明人： BOURHIS, Jean François Marie , GERMOND, Jean-François , MOECKLI, Raphaël , WUENSCH, Walter , GERBERSHAGEN, Alexander
IPC分类号： A61N5/10 , A61N2005/1089 , A61N5/1042
摘要： The present relates to a device for providing a radiation treatment to a patient comprising :- an electron source for providing a beam of electrons, and- a linear accelerator for accelerating said beam until a predetermined energy, and - a beam delivery module for delivering the accelerated beam from said linear accelerator toward the patient to treat a target volume with a radiation dose, The device further comprises intensity modulation means configured to modulate the distribution of the radiation dose in the target volume according to a predetermined pattern.The pattern is determined to match the dimensions of a target volume of at least about 50 cm3, and/or a target volume located at least about 5 cm deep in the tissue of the patient with said radiation dose,The radiation dose distributed is up to about 20 Gy delivered during an overall treatment time less than about 50 ms.

6. 发明申请

WO2015180952A1 PORTABLE RADIATION DETECTION DEVICE FOR OPERATION IN INTENSE MAGNETIC FIELDS 审中-公开
标题翻译：便携式辐射检测装置，用于强化磁场
公开(公告)号：WO2015180952A1
公开(公告)日：2015-12-03
申请号：PCT/EP2015/060371
申请日：2015-05-11
申请人： CERN - EUROPEAN ORGANIZATION FOR NUCLEAR RESEARCH , POLITECNICO DI MILANO
发明人： SILARI, Marco , FAZZI, Alberto , VAROLI, Vincenzo Antonio
IPC分类号： G01T1/20 , G01T1/208
CPC分类号： G01T1/2018 , G01T1/208
摘要： A portable radiation detection device with a detector unit comprising a scintillator with an array of avalanche photodiodes allows to reliably detect incident ionizing radiation or radiation contamination in the presence of intense magnetic fields of 0.1 Tesla and above.
摘要翻译：具有包括具有雪崩光电二极管阵列的闪烁体的检测器单元的便携式辐射检测装置允许在0.1特斯拉及以上的强磁场的存在下可靠地检测入射电离辐射或辐射污染。

7. 发明申请

WO2014207130A1 AC-CURRENT INDUCED QUENCH PROTECTION SYSTEM 审中-公开
标题翻译： AC电流感应猝灭保护系统
公开(公告)号：WO2014207130A1
公开(公告)日：2014-12-31
申请号：PCT/EP2014/063575
申请日：2014-06-26
申请人： CERN - EUROPEAN ORGANIZATION FOR NUCLEAR RESEARCH
发明人： KIRBY, Glyn Alistair , DATSKOV, Vladimir , RAVAIOLI, Emmanuele
IPC分类号： H01F6/02
CPC分类号： H02H7/001 , H01F6/02 , Y02E40/68
摘要： An apparatus (100) for quenching at least part (110) of a superconductor in a superconducting state in reply to a quench signal to initiate a transition from the superconducting state into a normal-conducting state comprises: means (120) for providing an alternating (AC) current of a predetermined strength and/or predetermined frequency to the at least part (110) of the superconductor, wherein the means (120) for providing the AC current comprises a control terminal (130) configured to receive the quench signal. The means (120) for providing the AC current is configured to be activated in response of receiving the quench signal at the control terminal (130) so that the AC current flows through the at least part (110) of the superconductor, wherein the predetermined strength and/or the predetermined frequency is selected such that the transition from the superconducting state into a normal- conducting state is triggered.
摘要翻译：一种用于在超导状态下淬火超导状态的至少一部分（110）的设备（100），以响应于淬火信号以引发从超导状态转变为正常导通状态的装置（100）包括：用于提供交替（110），其中用于提供所述AC电流的装置（120）包括被配置为接收所述骤冷信号的控制端子（130），所述控制端子（130）具有预定强度和/或预定频率的至少一部分（AC）电流。用于提供AC电流的装置（120）被配置为响应于在控制端（130）处接收到骤冷信号而被激活，使得AC电流流过超导体的至少部分（110），其中预定选择强度和/或预定频率使得从超导状态转变为正常导通状态被触发。

8. 发明申请

WO2014023473A2 RAPID BELLOWS COMPRESSION AND EXPANSION TOOL AND METHOD 审中-公开
标题翻译：快速的BELLOWS压缩和扩展工具和方法
公开(公告)号：WO2014023473A2
公开(公告)日：2014-02-13
申请号：PCT/EP2013/063519
申请日：2013-06-27
申请人： CERN - EUROPEAN ORGANIZATION FOR NUCLEAR RESEARCH
发明人： RAMBEAU, Herve
CPC分类号： B25B27/28 , F16L27/108 , F16L27/11 , F24F13/0209
摘要： A rapid bellows compression and/or expansion tool comprises a plurality of adjusting means that allow to adjust an axial distance between a first engaging member adapted to engage a bellows at a first portion thereof, and a second engaging member adapted to engage said bellows at a second opposing portion thereof. Transfer means are provided to mechanically couple the plurality of adjusting means, thereby providing for a uniform and synchronous bellows compression and/or expansion.
摘要翻译：快速波纹管压缩和/或膨胀工具包括多个调节装置，其允许调整适于在其第一部分处接合波纹管的第一接合构件与适于在一个第二接合构件处接合所述波纹管的第二接合构件第二相对部分。提供转移装置以机械地联接多个调节装置，从而提供均匀和同步的波纹管压缩和/或膨胀。

9. 发明申请

WO2011050884A1 METHOD FOR FABRICATING AN AMPLIFICATION GAP OF AN AVALANCHE PARTICLE DETECTOR 审中-公开
标题翻译：用于制造AVALANCHE颗粒检测器的放大空间的方法
公开(公告)号：WO2011050884A1
公开(公告)日：2011-05-05
申请号：PCT/EP2010/005729
申请日：2010-09-17
申请人： CERN - EUROPEAN ORGANIZATION FOR NUCLEAR RESEARCH , CEA , GIOMATARIS, Ioannis , DE OLIVEIRA, Rui
发明人： GIOMATARIS, Ioannis , DE OLIVEIRA, Rui
IPC分类号： H01J47/06
CPC分类号： H01J47/065 , H01J47/06
摘要： The invention relates to an improved method for fabricating the amplification gap of an avalanche particle detector in which two parallel electrodes are spaced apart by dielectric spacer elements. A foil including a bulk layer made of dielectric material sandwiched by two mutually parallel metallic electrodes is provided, and holes are formed in one of the metallic layers by means of photolithography. The amplification gap is then formed in the bulk layer by means of carefully controlled etching of the bulk material through the holes formed in one of the metallic layers. The invention not only provides a simplified fabrication process, but also results in a detector with enhanced spatial and energy resolution.
摘要翻译：本发明涉及一种用于制造雪崩粒子检测器的放大间隙的改进方法，其中两个平行电极由电介质间隔元件隔开。提供了包括由两个相互平行的金属电极夹持的电介质材料制成的体层的箔，并且通过光刻法在一个金属层中形成孔。然后通过对通过在一个金属层中形成的孔形成的本体材料进行仔细控制的蚀刻，在体层中形成放大间隙。本发明不仅提供了简化的制造工艺，而且还产生具有增强的空间和能量分辨率的检测器。

10. 发明申请

WO2008110182A1 METHOD, APPARATUS AND COMPUTER PROGRAM FOR MEASURING THE DOSE, DOSE RATE OR COMPOSITION OF RADIATION 审中-公开
标题翻译：用于测量剂量，剂量率或辐射组成的方法，装置和计算机程序
公开(公告)号：WO2008110182A1
公开(公告)日：2008-09-18
申请号：PCT/EP2007/002105
申请日：2007-03-09
申请人： CERN - EUROPEAN ORGANIZATION FOR NUCLEAR RESEARCH , CZECH TECHNICAL UNIVERSITY OF PRAGUE , HEIJNE, Erik, Henricus, M. , POSPISIL, Stanislav
发明人： HEIJNE, Erik, Henricus, M. , POSPISIL, Stanislav
IPC分类号： G01T1/02 , G01T5/02
CPC分类号： G01T1/026 , G01T5/02
摘要： A method and an apparatus for measuring the dose, the dose rate and/or the composition of radiation is disclosed. In the method, a detector means (10) is exposed to a radiation environment, the detector means (10) comprising an array of radiation sensing detector elements. The detector means (10) is switched in a sensitive state for the duration of a sensitive time period, and during said sensitive time period, an interaction pattern generated by individual radiation quanta interacting with one or more of the detector elements is recorded. The duration of the sensitive time period can be precisely adapted to the intensity of the radiation that has to be recorded. The interaction pattern is analyzed to distinguish individual radiation quanta received during the sensitive time period, and a radiation category is assigned to each of the distinguished radiation quanta based on its corresponding interaction pattern. A dose, a dose rate and/or a composition of radiation is then computed from the detected and categorized radiation quanta. Weight factors are attributed to each radiation category to take into account the individual degree of damage which the corresponding category can inflict in the irradiated materials.
摘要翻译：公开了用于测量辐射的剂量，剂量率和/或组成的方法和装置。在该方法中，检测器装置（10）暴露于辐射环境，检测器装置（10）包括辐射感测检测器元件阵列。检测器装置（10）在灵敏时间段的持续时间内被切换成敏感状态，并且在所述灵敏时间段期间，记录与一个或多个检测器元件相互作用的各个辐射量子产生的相互作用图案。灵敏时间段的持续时间可以精确地适应于必须记录的辐射强度。分析相互作用模式以区分在敏感时间段期间接收的个体辐射量子，并且基于其对应的相互作用模式将辐射类别分配给每个识别的辐射量子。然后从检测和分类的辐射量子计算剂量，剂量率和/或辐射组成。重量因子归因于每个辐射类别，以考虑相应类别可能在辐射材料中造成的个体损害程度。

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