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    • 4. 发明申请
    • APPARATUS AND METHODS FOR ANALYZING BODY FLUID SAMPLES
    • 用于分析身体液体样品的装置和方法
    • WO2006088771A2
    • 2006-08-24
    • PCT/US2006004928
    • 2006-02-13
    • OPTISCAN BIOMEDICAL CORPHALL W DALECALLICOAT DAVID NGABLE JENNIFER HBRAIG JAMES RWITTE KENNETH GWESCHLER MARKRULE PETERKEENAN RICHARD
    • HALL W DALECALLICOAT DAVID NGABLE JENNIFER HBRAIG JAMES RWITTE KENNETH GWESCHLER MARKRULE PETERKEENAN RICHARD
    • A61B5/15A61B5/00A61M5/172G01N33/487
    • A61B5/14546A61B5/15003A61B5/150213A61B5/150221A61B5/150229A61B5/150358A61B5/150755A61B5/150862A61B5/150992A61B5/153A61B5/155A61B5/157A61M5/14212A61M2230/20
    • An apparatus is provided for monitoring a predetermined parameter of a patient's body fluid while infusing an infusion fluid into the patient. The apparatus comprises an infusion line and a catheter configured for insertion into a blood vessel of the patient, and a reversible infusion pump connected between a source of an infusion fluid and the infusion line and catheter. The apparatus further comprises a body fluid sensor assembly mounted in fluid communication with the infusion line and which includes a first sensor and a sample cell. The first sensor provides a signal indicative of a predetermined parameter of any fluid present in the infusion line. The sample cell is substantially transmissive to light comprising a wavelength ?. The apparatus further comprises a controller that is configured to operate the infusion pump in a forward direction so as to pump the infusion fluid through the infusion line and catheter for infusion into the patient. The controller is configured to intermittently interrupt its operating of the infusion pump in the forward direction to operate the infusion pump in a rearward direction so as to draw a body fluid sample from the patient through the catheter and infusion line. The body fluid sample drawn from the patient is disposed such that a first portion of the body fluid sample is in sensing contact with the first sensor of the body fluid sensor assembly, and a second portion of the body fluid sample is disposed within the sample cell of the body fluid sensor assembly. The controller further is configured to monitor the signal provided by the first sensor of the body fluid sensor assembly and to detect a change in the signal indicative of the arrival of the body fluid sample at the first sensor. The controller, in response to detecting the arrival of the body fluid sample at the first sensor, is configured to cease its operating of the infusion pump in the rearward direction. The signal produced by the first sensor provides an indication of a predetermined parameter of the patient's body fluid when the body fluid sample is in sensing contact with the first sensor.
    • 提供了一种用于在将输注液注入患者体内时监测患者体液的预定参数的装置。 该装置包括输注管线和构造成用于插入患者血管的导管以及连接在输注液源和输注管线和导管之间的可逆输液泵。 该装置还包括体液传感器组件,其安装成与输注管线流体连通并且包括第一传感器和样品池。 第一传感器提供指示输注管线中存在的任何流体的预定参数的信号。 样品池对于包含波长λ的光是基本上透射的。 所述装置还包括控制器,所述控制器被配置为沿向前方向操作所述输注泵,以便将所述输注流体泵送通过所述输注管线和导管以输注到所述患者体内。 控制器被配置为间歇地中断其在向前方向上的输液泵的操作,以在向后的方向上操作输注泵,以便通过导管和输注管线从患者抽取体液样品。 从患者抽出的体液样品被设置成使得体液样品的第一部分与体液传感器组件的第一传感器感测接触,并且体液样品的第二部分设置在样品池内 的体液传感器组件。 控制器还被配置为监测由体液传感器组件的第一传感器提供的信号,并且检测指示体液样品到达第一传感器的信号的变化。 响应于检测体液样品到达第一传感器,控制器被配置为在向后的方向停止输注泵的操作。 当体液样品与第一传感器感测接触时,由第一传感器产生的信号提供患者体液的预定参数的指示。