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1. 发明申请

WO2003038726A2 A METHOD FOR EPIGENETIC KNOWLEDGE GENERATION 审中-公开
标题翻译：一种用于知识产生知识的方法
公开(公告)号：WO2003038726A2
公开(公告)日：2003-05-08
申请号：PCT/EP2002/011960
申请日：2002-10-25
申请人： EPIGENOMICS AG , BERLIN, Kurt , BRAUN, Aron , ADORJAN, Peter
发明人： BERLIN, Kurt , BRAUN, Aron , ADORJAN, Peter
IPC分类号： G06F19/00
CPC分类号： C12Q1/6809 , G06F19/24 , G06F19/28
摘要： A method for epigenetic knowledge generation which designs and synthesizes the chemical and/or biological components that determine the epigenetic parameters to be selected and measured is described. The value of these epigenetic parameters is determined, the steps of this procedure repeated and finally the results are stored.The present invention relates to a method of epigenetic knowledge generation comprising the steps of: a. selecting epigenetic parameters of interest; b. designing the chemical and/or biological components of the epigenetic measurement system, wherein the chemical and/or biological components determine the epigenetic parameters to be measured; c. synthesizing the variable chemical and/or biological components; d. measuring the value of the epigenetic parameters using the chemical and/or biological components; e. storing the results obtained by measurement; f. defining a subset of epigenetic parameters of interest based on the measurements;g. repeating steps a-d.
摘要翻译：描述了设计和合成确定待选择和测量的表观遗传参数的化学和/或生物成分的表观遗传知识产生的方法。确定这些表观遗传参数的值，重复该过程的步骤，最后将结果存储起来。本发明涉及一种表观遗传知识产生方法，包括以下步骤：a。选择感兴趣的表观遗传参数; 湾设计表观遗传学测量系统的化学和/或生物组分，其中所述化学和/或生物组分决定待测量的表观遗传参数; C。合成可变化学和/或生物成分; 天。使用化学和/或生物成分测量表观遗传参数的值; 即存储通过测量获得的结果; F。基于测量定义感兴趣的表观遗传参数的子集; g。重复步骤a-d。

2. 发明申请

WO2003038726A3 A METHOD FOR EPIGENETIC KNOWLEDGE GENERATION 审中-公开
公开(公告)号：WO2003038726A3
公开(公告)日：2003-05-08
申请号：PCT/EP2002/011960
申请日：2002-10-25
申请人： EPIGENOMICS AG , BERLIN, Kurt , BRAUN, Aron , ADORJAN, Peter
发明人： BERLIN, Kurt , BRAUN, Aron , ADORJAN, Peter
IPC分类号： G06F19/00
摘要： A method for epigenetic knowledge generation which designs and synthesizes the chemical and/or biological components that determine the epigenetic parameters to be selected and measured is described. The value of these epigenetic parameters is determined, the steps of this procedure repeated and finally the results are stored. The present invention relates to a method of epigenetic knowledge generation comprising the steps of: a. selecting epigenetic parameters of interest; b. designing the chemical and/or biological components of the epigenetic measurement system, wherein the chemical and/or biological components determine the epigenetic parameters to be measured; c. synthesizing the variable chemical and/or biological components; d. measuring the value of the epigenetic parameters using the chemical and/or biological components; e. storing the results obtained by measurement; f. defining a subset of epigenetic parameters of interest based on the measurements; g. repeating steps a-d.

3. 发明申请

WO0249474A3 PIECE OF JEWELRY BEARING A GENETIC FINGERPRINT 审中-公开
标题翻译：具有遗传指纹的珠宝首饰
公开(公告)号：WO0249474A3
公开(公告)日：2002-12-27
申请号：PCT/DE0104963
申请日：2001-12-21
申请人： OLEK ALEXANDER , REUTER CHRISTINE , HEUERMANN ARNO , BERLIN KURT , BERLIN KATHRIN , SCHACHT OLIVER , PIEPENBROCK CHRISTIAN , BRAUN ARON
发明人： OLEK ALEXANDER
IPC分类号： A44C5/00 , A44C9/00 , A44C25/00 , A44C27/00
CPC分类号： A44C9/00 , A44C5/0015
摘要： The invention relates to pieces of jewelry that are provided to be worn by an individual and that are characterized by bearing genetic information about the individual wearing them or about a different individual. In a preferred embodiment, these pieces of jewelry are wedding or engagement rings.
摘要翻译：所描述的是珠宝物品，其设计为由个人穿戴，并且通过携带携带它的个体或关于其他个体的个体的遗传信息而被区分。在一个优选实施例中，这些珠宝物品是婚戒或订婚戒指。

4. 发明申请

WO2002077272A2 METHODS AND NUCLEIC ACIDS FOR THE ANALYSIS OF HEMATOPOIETIC CELL PROLIFERATIVE DISORDERS 审中-公开
标题翻译： HEMATOPOIETIC细胞增殖性疾病分析的方法和核酸
公开(公告)号：WO2002077272A2
公开(公告)日：2002-10-03
申请号：PCT/EP2002/003401
申请日：2002-03-26
申请人： EPIGENOMICS AG , BERLIN, Kurt , BRAUN, Aron , DISTLER, Jürgen , GÜTIG, David , HOWE, André , MÜLLER, Jürgen , OLEK, Alexander , PIEPENBROCK, Christian , ADORJAN, Peter , GRABS, Gabi , LESCHE, Ralf , LEU, Erik , LEWIN, Andre , LIPSCHER, Evelyne , MAIER, Sabine , MODEL, Fabian , MÜLLER, Volker , OTTO, Thomas , PELET, Cecile , SCHWOPE, Ina , ZIEBARTH, Heike
发明人： BERLIN, Kurt , BRAUN, Aron , DISTLER, Jürgen , GÜTIG, David , HOWE, André , MÜLLER, Jürgen , OLEK, Alexander , PIEPENBROCK, Christian , ADORJAN, Peter , GRABS, Gabi , LESCHE, Ralf , LEU, Erik , LEWIN, Andre , LIPSCHER, Evelyne , MAIER, Sabine , MODEL, Fabian , MÜLLER, Volker , OTTO, Thomas , PELET, Cecile , SCHWOPE, Ina , ZIEBARTH, Heike
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6883 , C12Q2600/112 , C12Q2600/154 , C12Q2600/158 , C12Q2600/16 , Y02A90/24 , Y02A90/26
摘要： The present invention relates to modified and genomic sequences, to oligonucleotides and/or PNA-oligomers for detecting the cytosine methylation state of genomic DNA, as well as to a method for ascertaining genetic and/or epigenetic parameters of genes for use in the differentiation, diagnosis, treatment and/or monitoring of hematopoietic cell proliferative disorders, or the predisposition to hematopoietic cell proliferative disorders.
摘要翻译：本发明涉及修饰和基因组序列，用于检测基因组DNA的胞嘧啶甲基化状态的寡核苷酸和/或PNA寡聚体，以及用于确定用于分化的基因的遗传和/或表观遗传学参数的方法，诊断，治疗和/或监测造血细胞增殖性疾病，或造血细胞增殖性疾病的倾向。

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