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2. 发明申请

WO2003030921A1 Methods for producing agrimonia extract with improved activity against hepatitis B virus and pharmaceutical and food compositions containing said extract 审中-公开
标题翻译：用于生产具有改善乙型肝炎病毒活性的农药提取物的方法和含有所述提取物的药物和食品组合物
公开(公告)号：WO2003030921A1
公开(公告)日：2003-04-17
申请号：PCT/KR2002/001888
申请日：2002-10-09
申请人： BIOKOREA CO., LTD , LEE, Young-Sung , AHN, Dong-Ho , HONG, Sa-Min , YOON, Seung-Kew , CHANG, Eun-Joo , LEE, Min-Kyung , KWON, Hyok-Yun
发明人： LEE, Young-Sung , AHN, Dong-Ho , HONG, Sa-Min , YOON, Seung-Kew , CHANG, Eun-Joo , LEE, Min-Kyung , KWON, Hyok-Yun
IPC分类号： A61K35/78
CPC分类号： A61K36/73 , A23L33/105
摘要： Disclosed are pharmaceutical and food compositions for preventing or treating hepatic disease, containing a pharmaceutically effective amount of an extract from a plant Agrimonia eupatoria L. . Also, the present invention discloses a method of preparing a water-soluble extract from a plant of the genus Agrimonia , which has improved efficacy in preventing or treating hepatic diseases, characterized by heating a mixture of a pulverized product of a plant of the genus Agrimonia and water at about 20°C to 30°C for about 7 days or more, and pharmaceutical and food compositions for preventing or treating a hepatic disease, containing a water-soluble extract prepared according to the method. Further, the present invention discloses a method of preparing an organic solvent-soluble extract from a plant of the genus Agrimonia , which has improved efficacy in preventing or treating hepatic diseases, comprising the steps of extracting a plant of the genus Agrimonia with an organic solvent, and removing an aqueous fraction and then obtaining an organic solvent-soluble fraction, and pharmaceutical and food compositions for preventing or treating hepatic disease, containing an extract prepared according to the method.
摘要翻译：公开了用于预防或治疗肝脏疾病的药物和食品组合物，其含有药学有效量的来自植物Agrimonia eupatoria L的提取物。此外，本发明公开了一种从该属植物制备水溶性提取物的方法其具有改善预防或治疗肝脏疾病的功效，其特征在于在大约20℃至30℃加热Agrimonia属植物的粉碎产物和水的混合物约7天或更长时间，药物和用于预防或治疗肝病的食品组合物，其含有根据该方法制备的水溶性提取物。此外，本发明公开了一种制备有机溶剂可溶性提取物的方法，所述提取物具有改善预防或治疗肝病的功效，其特征在于包括以下步骤：用有机溶剂提取Agrimonia属植物并除去含水部分，然后得到有机溶剂可溶性部分，以及含有根据该方法制备的提取物的用于预防或治疗肝病的药物和食品组合物。

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