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1. 发明申请

WO2012148905A3 POLYMERIC SOLAR CONCENTRATOR AND SOLAR THERMAL DEVICE INCORPORATING SAME 审中-公开
标题翻译：聚合太阳能集热器和太阳能热电偶装置
公开(公告)号：WO2012148905A3
公开(公告)日：2013-01-17
申请号：PCT/US2012034783
申请日：2012-04-24
申请人： MORNINGSIDE TECHNOLOGY VENTURES LTD , MSL TWO LTD , BATES DAVID J , HAYNES ANDREW L , PARTRIDGE ASHTON C
发明人： BATES DAVID J , HAYNES ANDREW L , PARTRIDGE ASHTON C
IPC分类号： F24S23/00 , F24S23/30 , G02B5/00
CPC分类号： F24J2/06 , F24J2/085 , G02B27/0955 , G02B27/0972 , Y02E10/43 , Y10T428/24355
摘要： Polymeric sheets suitable for use as solar concentrators in solar thermal devices are provided. Also provided are solar thermal devices incorporating the polymeric sheets. The polymeric sheets have two oppositely facing surfaces. A first pattern is defined in the first surface and a second pattern is defined in the second surface. The first pattern is designed to reduce the reflectance of light incident upon the first surface relative to the first surface in the absence of the first pattern and to channel incident light through the sheet onto the second surface. It does so by redirecting photons incident upon the first surface over a broad range of incident angles into transmittance angles that are more closely aligned with the surface normal of the polymeric sheet. The second pattern is designed to focus the photons transmitted to the second surface of the sheet onto a focal surface, such as a receptacle containing a heat-transfer medium.
摘要翻译：提供适合用作太阳能热设备中的太阳能聚光器的聚合物片材。还提供了并入聚合物片的太阳能热装置。聚合物片材具有两个相对的表面。在第一表面中限定第一图案，并且在第二表面中限定第二图案。第一图案被设计成在没有第一图案的情况下减少入射在第一表面上的光的反射率，并且将入射光通过片材引导到第二表面上。它通过将入射在第一表面上的光子在大范围的入射角度重定向成与聚合物片材的表面法线更接近的透射角度来实现。第二图案被设计成将传输到片材的第二表面的光子聚焦到焦面上，例如包含传热介质的容器。

2. 发明申请

WO2011036429A1 DETECTION OF RISK OF PRE-ECLAMPSIA 审中-公开
标题翻译：检测前驱体的风险
公开(公告)号：WO2011036429A1
公开(公告)日：2011-03-31
申请号：PCT/GB2009/051263
申请日：2009-09-25
申请人： THE UNIVERSITY OF BRISTOL , BATES, David, Owen , BILLS, Victoria, Louise , HARPER, Stephen, James , QIU, Yan
发明人： BATES, David, Owen , BILLS, Victoria, Louise , HARPER, Stephen, James , QIU, Yan
IPC分类号： G01N33/68 , C12Q1/68
CPC分类号： G01N33/689 , C12Q1/6883 , C12Q2600/118 , G01N2800/368
摘要： A method of detecting a risk of a pregnant female mammal developing pre-eclampsia or a complication linked thereto, or of a fetus of the pregnant female mammal developing a fetal or neonatal deficiency linked to maternal pre-eclampsia, comprises detecting the level of a VEGF xxx b in a sample from the pregnant female mammal at less than about 24 weeks of gestation and comparing the detected level with a reference level. A reduced level in the sample from the pregnant female mammal is indicative of a risk of the pregnant female mammal developing pre-eclampsia or a complication linked thereto or of the fetus developing the fetal or neonatal deficiency linked to maternal pre-eclampsia.
摘要翻译：一种检测怀孕的雌性哺乳动物发生先兆子痫或与之相关的并发症的风险的方法，或怀孕雌性哺乳动物胎儿发育与母体先兆子痫相关的胎儿或新生儿缺陷的方法包括检测VEGFxxxb的水平在怀孕雌性哺乳动物的妊娠少于约24周的样品中，并将检测到的水平与参考水平进行比较。来自怀孕的雌性哺乳动物的样品中的降低的水平表明怀孕的雌性哺乳动物发生先兆子痫或与之相关的并发症或胎儿发展与母体先兆子痫相关的胎儿或新生儿缺陷的风险。

3. 发明申请

WO2009113884A2 A ROBOT MILKING ARM AND A METHOD OF ATTACHING MILKING CUPS 审中-公开
标题翻译：一种机器人奶壶及一种附着奶杯的方法
公开(公告)号：WO2009113884A2
公开(公告)日：2009-09-17
申请号：PCT/NZ2009000036
申请日：2009-03-11
申请人： SCOTT MILKTECH LTD , SEATON MARK HAMISH , GLOVER THOMAS , GRIMSHAW BRYAN GORDAN , BATES DAVID , KNOTTS PETER , JACK MATTHEW
发明人： SEATON MARK HAMISH , GLOVER THOMAS , GRIMSHAW BRYAN GORDAN , BATES DAVID , KNOTTS PETER , JACK MATTHEW
CPC分类号： A01J5/0175 , A01K1/126
摘要： A robotic milking system suitable for use with conventional milking clusters. Clusters are withdrawn to a generally known position upon release from a cow with the cups hanging down below the bowl. The cups are then located in a confined region from where they are picked up by a robotic arm and attached to teats of a cow. The cups may be located into recesses or slots or be drawn through a guide. The arrangement allows a single robotic arm to service multiple bales of a rotary milking parlour. The application of a vacuum to milking cups may be controlled by applying sufficient pressure to the pulsation line of a cup to collapse the cup liner when that cup is not attached to a teat or by bending a feed line to a cup to close the flow path.
摘要翻译：适用于传统挤奶机群的机器人挤奶系统。当奶牛从杯子下面垂下来时，奶牛群会被释放到公知的位置。然后，杯子被放置在一个狭窄的区域，从机器人手臂拿起杯子并附在奶牛的奶嘴上。杯子可以位于凹槽或槽中或通过导向装置抽出。这种安排允许一个机器人手臂服务多个旋转式挤奶厅。可以通过向杯子的脉动线施加足够的压力以在杯子未附接至奶嘴时折叠杯子衬里或通过将馈送线弯曲至杯子以关闭流动路径来控制向挤奶杯施加真空。

4. 发明申请

WO2008110777A2 PRO- AND ANTI-ANGIOGENIC TREATMENTS 审中-公开
标题翻译：抗原性抗原治疗
公开(公告)号：WO2008110777A2
公开(公告)日：2008-09-18
申请号：PCT/GB2008/000824
申请日：2008-03-10
申请人： UNIVERSITY OF BRISTOL , BATES, David , HARPER, Steven, James , NOWAK, Dawid, Grzegorz
发明人： BATES, David , HARPER, Steven, James , NOWAK, Dawid, Grzegorz
IPC分类号： G01N33/50 , A61K31/535 , A61K38/17 , A61K38/18 , A61K38/19 , A61P9/00
CPC分类号： C12N15/1136 , A61K31/535 , C12N2310/11 , C12N2310/3233 , C12N2320/33
摘要： The invention provides a method of selectively pro-oranti-angiogenic treatment of a mammalian subject, comprising site-specific control of alternative splicing during processing of VEGF pre-mRNA transcribed from the C terminal exon 8 of the VEGF gene using controlling agents for the splicing, wherein one or more controlling agent which favours proximal splice site (PSS) splicing in said processing is used in the pro-angiogenic treatment and one or more controlling agent which favours distal splice site (DSS) splicing in said processing is used in the anti-angiogenic treatment.
摘要翻译：本发明提供了一种哺乳动物受试者的选择性前体或反 - 血管生成治疗方法，包括使用控制剂进行剪接处理从VEGF基因的C末端外显子8转录的VEGF前体mRNA处理期间的选择性剪接的位点特异性控制其中在所述处理中使用有利于所述处理中的近端剪接位点（PSS）剪接的一种或多种控制剂用于促血管生成治疗，并且在所述处理中使用有利于所述处理中的远端剪接位点（DSS）剪接的一种或多种控制剂，血管生成治疗。

5. 发明申请

WO0108669A3 THERAPEUTIC AGENTS FOR LYMPHOEDEMA 审中-公开
标题翻译： LYMPHOEDEMA治疗药物
公开(公告)号：WO0108669A3
公开(公告)日：2002-07-11
申请号：PCT/GB0002950
申请日：2000-07-31
申请人： UNIV BRISTOL , BATES DAVID
发明人： BATES DAVID
IPC分类号： A61K31/00 , A61K31/235 , A61K31/275 , A61K31/277 , A61K31/38 , A61K31/40 , A61K31/415 , A61K31/42 , A61K31/495 , A61K31/502 , A61K31/505 , A61K31/517 , A61K31/535 , A61P7/10 , C12Q1/48
CPC分类号： A61K31/535 , A61K31/00 , A61K31/235 , A61K31/275 , A61K31/277 , A61K31/38 , A61K31/40 , A61K31/415 , A61K31/42 , A61K31/495 , A61K31/502 , A61K31/505 , A61K31/517 , G01N2333/71
摘要： The use of an agent which selectively inhibits, prevents or interferes with the signal transduced by flk-1/KDR when activated by a ligand, in the manufacture of a medicament for the treatment of lymphoedema and in a method for reducing the filtration rate from blood to tissue. Also provided is a method for identifying compounds useful in the treatment of lymphoedema, and compounds identified thereby.
摘要翻译：在制备用于治疗淋巴水肿的药物中的选择性抑制，预防或干扰由配体激活时由flk-1 / KDR转导的信号的药剂的使用，以及用于降低血液中过滤速率的方法到组织。还提供了用于鉴定可用于治疗淋巴水肿的化合物的方法和由此鉴定的化合物。

6. 发明申请

WO1996014761A1 METHOD AND APPARATUS FOR WRAPPING A ROD OF SMOKING MATERIAL 审中-公开
标题翻译：用于包裹吸烟材料的方法和装置
公开(公告)号：WO1996014761A1
公开(公告)日：1996-05-23
申请号：PCT/GB1995002667
申请日：1995-11-14
申请人： ROTHMANS INTERNATIONAL SERVICES LIMITED , PARKER, Michael, Patrick , BATES, David, John , BRAY, Andrew, Jonathan , LAUGHTON, Jonathan, Charles , STEWART-COX, Adrian, Roy
发明人： ROTHMANS INTERNATIONAL SERVICES LIMITED
IPC分类号： A24D01/02
CPC分类号： A24C1/30 , A24C5/1807 , A24D1/02
摘要： The effect of spiral-wrapping of a tobacco rod is obtained by providing a wrap material (1) having edge portions (3) which are angled to an edge (4) which is to be arranged axially of the tobacco rod when the material is wrapped cylindrically around the tobacco. Discontinuities (5) between inclined edge portions (3) are preferred positions for the severing of rods wrapped with the material, into cigarette lengths. Methods and apparatus are disclosed for wrapping or overwrapping with this material to form the tobacco rod.
摘要翻译：通过提供具有边缘部分（3）的包裹材料（1）来获得烟草棒的螺旋缠绕的效果，所述边缘部分（3）与当边缘（4）成一角度时，当边缘围绕烟草圆柱形。倾斜边缘部分（3）之间的不连续性（5）是用于将用材料包裹的棒切断成卷烟长度的优选位置。公开了用该材料包裹或包裹以形成烟草棒的方法和设备。

7. 发明申请

WO2022067189A1 SYSTEMS AND METHODS FOR MACHINE-LEARNING-ASSISTED COGNITIVE EVALUATION AND TREATMENT 审中-公开
公开(公告)号：WO2022067189A1
公开(公告)日：2022-03-31
申请号：PCT/US2021/052218
申请日：2021-09-27
申请人： LINUS HEALTH, INC. , PASCUAL-LEONE, Alvaro , SOUILLARD-MANDAR, William , ROGERS, Emily , BACON, Jeff , LANGTON, John , TOBYNE, Sean , THOMPSON, Karl , BATES, David
发明人： PASCUAL-LEONE, Alvaro , SOUILLARD-MANDAR, William , ROGERS, Emily , BACON, Jeff , LANGTON, John , TOBYNE, Sean , THOMPSON, Karl , BATES, David
IPC分类号： A61B5/00
摘要： Systems, methods, and computer program products are provided for determining one or more biomarker and/or health condition of a target patient. In various embodiments, a method is provided where a plurality of health data of the target patient and/or a plurality of first order features determined from the plurality of health data of the target patient are received as input to a pre-trained artificial neural network. The plurality of health data is derived from a plurality of modalities. A plurality of latent variables based on the plurality of health data and plurality of first order features are received from an intermediate layer of the pre-trained artificial neural network. The plurality of latent variables are provided to a pre-trained learning system. The pre-trained learning system is trained to receive as input the plurality of latent variables and output one or more biomarker and/or health condition of the target patient.

8. 发明申请

WO2015100580A1 METHOD AND SYSTEM FOR ENHANCED VISUALIZATION BY AUTOMATICALLY ADJUSTING ULTRASOUND NEEDLE RECOGNITION PARAMETERS 审中-公开
标题翻译：自动调整超声波识别参数的增强可视化方法与系统
公开(公告)号：WO2015100580A1
公开(公告)日：2015-07-09
申请号：PCT/CN2013/091021
申请日：2013-12-31
申请人： GENERAL ELECTRIC COMPANY , LIN, Feng , PEIFFER, Jeffery Scott , KANG, Eunji , HALMANN, Menachem , LI, Bo , BATES, David J.
发明人： LIN, Feng , PEIFFER, Jeffery Scott , KANG, Eunji , HALMANN, Menachem , LI, Bo , BATES, David J.
IPC分类号： A61B8/00
CPC分类号： A61B8/0841 , A61B8/4483 , A61B8/463 , A61B8/467 , A61B8/5207 , A61B8/5253 , A61B8/54 , A61B2017/3413 , A61B2034/2051 , G01S7/5208 , G01S15/8913 , G01S15/8915 , G01S15/899 , G01S15/8995
摘要： An ultrasound device (100) determines a position and orientation of a surgical instrument (10) based at least in part on tracking information, such as magnetic field strength, emitted by an emitter (14) of a tracking system and detected by a sensor (112) of the tracking system. The sensor (112) and the emitter (14) are attached to or within a different one of a probe (104) of the ultrasound device (100) and the surgical instrument (10). The ultrasound device (100) determines an ultrasound imaging parameter, such as an ultrasound beam steering angle, based at least in part on the determined position and orientation of the surgical instrument (10). The ultrasound device (100) applies the ultrasound imaging parameter to acquire ultrasound image data of a target. The ultrasound device (100) generates an ultrasound image based on the acquired ultrasound image data of the target. The ultrasound image includes a representation of the surgical instrument (10). The surgical instrument (10) may be a needle.
摘要翻译：超声波装置（100）至少部分地基于由跟踪系统的发射器（14）发射并由传感器检测的跟踪信息（例如磁场强度）来确定外科器械（10）的位置和取向 112）的跟踪系统。传感器（112）和发射器（14）附接到超声波装置（100）的探头（104）和外科器械（10）中的不同的一个中。超声装置（100）至少部分地基于所确定的外科器械（10）的位置和取向来确定超声波成像参数，例如超声波束转向角。超声波装置（100）应用超声波成像参数来获取目标的超声图像数据。超声波装置（100）基于取得的目标的超声波图像数据生成超声波图像。超声波图像包括外科器械（10）的表示。手术器械（10）可以是针。

9. 发明申请

WO2008019307A3 WIDEBAND DIELECTRIC WAVEGUIDE FILTER 审中-公开
标题翻译：宽带介质波导滤波器
公开(公告)号：WO2008019307A3
公开(公告)日：2008-12-11
申请号：PCT/US2007075153
申请日：2007-08-03
申请人： DIELECTRIC LAB , BATES DAVID ALLEN , GOKTEN MESUT
发明人： BATES DAVID ALLEN , GOKTEN MESUT
IPC分类号： H01P1/20 , H01P1/202 , H01P1/213
CPC分类号： H01P1/208 , H01P1/2088
摘要： A waveguide-type dielectric filter suitable for wideband filter applications made of a metallized dielectric material is provided. The filter includes two or more mutually coupled resonators disposed in a longitudinal manner. The coupling between adjacent resonators is provided and adjusted by slots or through holes. The dielectric block is covered with metal ground coating with the exception of an uncoated area at the input and output that creates two contact pads on one surface of the dielectric block that are electrically isolated from the metal ground coating. Metallized blind holes are formed on the opposing surface of the dielectric block with respect to the contact pads. These blind holes effectively move the ground plane closer to the contact pad, which, in turn increases the coupling between the input and output resonators and external circuitry, which is essential for building wide bandwidth band pass filters,
摘要翻译：提供适用于由金属化介电材料制成的宽带滤波器应用的波导型介电滤波器。滤波器包括以纵向方式设置的两个或更多个相互耦合的谐振器。相邻谐振器之间的耦合由槽或通孔提供和调整。除了输入和输出处的未涂覆区域之外，介质块被金属地面涂层覆盖，从而在介质块的一个表面上产生与金属地面涂层电隔离的两个接触焊盘。金属化盲孔相对于接触焊盘形成在介质块的相对表面上。这些盲孔有效地将接地层移近接触焊盘，这反过来又增加了输入和输出谐振器与外部电路之间的耦合，这对于构建宽带宽带通滤波器是必不可少的，

10. 发明申请

WO2005099401A2 DISCRETE RESONATOR MADE OF DIELECTRIC MATERIAL 审中-公开
标题翻译：介质材料的离散谐振器
公开(公告)号：WO2005099401A2
公开(公告)日：2005-10-27
申请号：PCT/US2005/011930
申请日：2005-04-08
申请人： DELAWARE CAPITAL FORMATION, INC. , BATES, David Allen
发明人： BATES, David Allen
IPC分类号： H01P1/201 , H01P7/10
CPC分类号： H01P7/10
摘要： A discrete resonator is provided, including a dielectric base having a dielectric constant. A metal contact formed on a major surface of the dielectric base has a predetermined area and is positioned at a predetermined location on the dielectric base to provide a predetermined loaded Q for the resonator. A metal ground coating is formed on the outer surface of the dielectric base with the exception of an isolation region surrounding the metal contact that is free of the metal ground coating. The area of the isolation region is sufficient to prevent significant coupling between the metal contact and the metal ground coating. The dielectric constant of the material used for the base, and the width and length of the dielectric base are each selected such that the resonator resonates at least at one predetermined resonant frequency in the GHz frequency range.
摘要翻译：提供了分立的谐振器，包括具有介电常数的电介质基底。形成在电介质基底的主表面上的金属接触件具有预定的面积并且位于电介质基底上的预定位置处，以为谐振器提供预定的加载的Q。金属接地涂层形成在电介质基体的外表面上，除了围绕金属接触件的隔离区域，该隔离区域没有金属地面涂层。隔离区域的面积足以防止金属接触和金属地面涂层之间的显着的耦合。用于基底的材料的介电常数以及电介质基底的宽度和长度各自被选择为使得谐振器在GHz频率范围内至少谐振至少一个预定的谐振频率。

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