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1. 发明申请

WO2012085807A1 STENT WITH SHEATH AND METAL WIRE RETAINER 审中-公开
标题翻译：与管和金属线保持器
公开(公告)号：WO2012085807A1
公开(公告)日：2012-06-28
申请号：PCT/IB2011/055758
申请日：2011-12-18
申请人： INSPIREMD LTD. , BAR, Eli , PAZ, Ofir , HOLZER, Asher
发明人： BAR, Eli , PAZ, Ofir , HOLZER, Asher
IPC分类号： A61F2/86
CPC分类号： A61F2/07 , A61F2/852 , A61F2/90 , A61F2/91 , A61F2002/0086 , A61F2002/075 , A61F2220/0058 , A61F2250/0063 , B23K11/11 , D04B1/225 , D10B2509/06 , Y10T29/49826
摘要： A stent assembly (20) includes a stent (22) and a fiber mesh sleeve (24) covering the stent. A wire (28) runs along the stent over the sleeve and fastened to the stent at multiple points (30) so as to attach the sleeve to the stent.
摘要翻译：支架组件（20）包括支架（22）和覆盖支架的纤维网套筒（24）。线（28）沿着支架延伸穿过套管并且在多个点（30）处固定到支架上，以将套筒附接到支架上。

2. 发明申请

WO2008109432A2 THERAPEUTIC TARGETING OF INTERLEUKINS USING SIRNA IN NEUTRAL LIPOSOMES 审中-公开
标题翻译：利用中性脂质体中的SIRNA治疗白血病的靶向治疗
公开(公告)号：WO2008109432A2
公开(公告)日：2008-09-12
申请号：PCT/US2008055486
申请日：2008-02-29
申请人： UNIV TEXAS , MERRITT WILLIAM K , SOOD ANIL K , BAR-ELI MENASHE , LOPEZ-BERESTEIN GABRIEL
发明人： MERRITT WILLIAM K , SOOD ANIL K , BAR-ELI MENASHE , LOPEZ-BERESTEIN GABRIEL
IPC分类号： A61K48/00 , C12N15/113
CPC分类号： C12N15/1136 , A61K9/127 , A61K45/06 , C12N2310/14 , C12N2320/31
摘要： The present invention relates to the fields of molecular biology and drug delivery. In certain embodiments, the present invention provides compositions that include an siRNA targeted to an interleukin and a neutral lipid, and methods of treating a human subject with cancer involving administering to the subject a pharmarceutically effective amount of an interleukin-8 antagonist or a composition as set forth herein.
摘要翻译：本发明涉及分子生物学和药物递送领域。在某些实施方案中，本发明提供了包含靶向白细胞介素和中性脂质的siRNA的组合物，以及治疗患有癌症的人类受试者的方法，所述方法包括向受试者施用药学上有效量的白细胞介素-8拮抗剂或组合物作为在此陈述。

3. 发明申请

WO2004052192A1 PHYSIOLOGICAL CONDITION MONITOR 审中-公开
标题翻译：生理条件监测
公开(公告)号：WO2004052192A1
公开(公告)日：2004-06-24
申请号：PCT/US2003/025187
申请日：2003-08-13
申请人： MCINNIS, Patricia , MCINNIS, Patricia , BAR, Eli
发明人： BAR, Eli
IPC分类号： A61B5/00
CPC分类号： A61B5/681 , A61B5/0452 , A61B5/0464 , A61B5/685
摘要： A device for monitoring a physiological condition of an individual, the device including: a monitoring unit (14) composed of at least one electrode (12)constructed to be placed in contact with the skin of the individual to produce a signal corresponding to the physiological condition, an amplifier coupled to the electrode to amplify the signal produced by the electrode, and a signal processing unit coupled to the amplifier to process the amplified signal from the amplifier in order to derive an indication of the physiological condition; and an attachment member (22) for securing the unit to the skin of the individual at a selected location with the electrode in contact with the skin.
摘要翻译：一种用于监测个体的生理状况的装置，所述装置包括：监测单元（14），其由至少一个电极（12）构成，所述至少一个电极构造成与个体的皮肤接触以产生对应于生理条件，耦合到所述电极以放大由所述电极产生的信号的放大器的放大器以及耦合到所述放大器以处理来自所述放大器的放大信号的信号处理单元，以便导出所述生理状态的指示; 以及用于在所选择的位置将所述单元固定到所述个体的皮肤的附接构件（22），所述电极与皮肤接触。

4. 发明申请

WO2002074191A2 PORTABLE ELECTROSPINNING DEVICE 审中-公开
标题翻译：便携式电动装置
公开(公告)号：WO2002074191A2
公开(公告)日：2002-09-26
申请号：PCT/IL2002/000220
申请日：2002-03-19
申请人： NICAST LTD. , DUBSON, Alexander , BAR, Eli
发明人： DUBSON, Alexander , BAR, Eli
IPC分类号： A61F
CPC分类号： D04H3/16 , A61F2250/0023 , A61F2250/0067 , A61L27/56 , B29C67/20 , D01D5/0092 , D04H1/728 , D04H3/07
摘要： An electrospinning device for generating a coat from a liquefied polymer, the device comprising: (a) a dispenser for dispensing the liquefied polymer; (b) a cavity having a longitudinal axis, comprising a first system of electrodes; the dispenser and the first system of electrodes being constructed and design such that the liquefied polymer is dispensed from the dispenser and forms a plurality of polymer fibers moving along the longitudinal axis; and (c) a mechanism for relocating the polymer fibers out of the cavity, in a direction of an object, so as to generate a coat on the object.
摘要翻译：一种用于从液化聚合物产生涂层的静电纺丝装置，所述装置包括：（a）用于分配液化聚合物的分配器; （b）具有纵轴的空腔，包括第一电极系统; 分配器和第一电极系统被构造和设计成使得液体聚合物从分配器分配并形成沿着纵向轴线移动的多个聚合物纤维; 和（c）将聚合物纤维从物体的方向上移出空腔的机构，以便在物体上产生涂层。

5. 发明申请

WO2002049678A3 METHOD AND APPARATUS FOR MANUFACTURING POLYMER FIBER SHELLS VIA ELECTROSPINNING 审中-公开
公开(公告)号：WO2002049678A3
公开(公告)日：2002-06-27
申请号：PCT/IL2001/001168
申请日：2001-12-17
申请人： NICAST LTD. , DUBSON, Alexander , BAR, Eli
发明人： DUBSON, Alexander , BAR, Eli
IPC分类号： B29B013/08
摘要： An apparatus for manufacturing a polymer fiber shell from liquefied polymer is provided. The apparatus includes: (a) a precipitation electrode being for generating the polymer fiber shell thereupon; (b) a dispenser, being at a first potential relative to the precipitation electrode so as to generate an electric field between the precipitation electrode and the dispenser, the dispenser being for: (i) charging the liquefied polymer thereby providing a charged liquefied polymer; and (ii) dispensing the charged liquefied polymer in a direction of the precipitation electrode; and (c) a subsidiary electrode being at a second potential relative to the precipitation electrode, the subsidiary electrode being for modifying the electric field between the precipitation electrode and the dispenser.

6. 发明申请

WO2007138578A2 IMPLANTABLE DYNAMIC PUMP DEVICE 审中-公开
标题翻译：可植入式动力泵装置
公开(公告)号：WO2007138578A2
公开(公告)日：2007-12-06
申请号：PCT/IL2007000638
申请日：2007-05-27
申请人： INTERVENTIONAL LUNG THERAPEUTI , RUBEN DANIEL , DARVISH NISSIM , BAR ELI
发明人： RUBEN DANIEL , DARVISH NISSIM , BAR ELI
IPC分类号： A61F2/24
CPC分类号： A61F2/04 , A61B17/12104 , A61F2/24 , A61F2002/043 , A61F2250/0001 , A61M1/1008 , A61M1/1096 , A61M1/12 , A61M1/127 , A61M2205/8206
摘要： An implantable dynamic pump device for fluid control inside body passage is disclosed. The device comprises a one-way valve, the valve sealably deployable within the body passage and provided with a deployable structure comprising at least one deployable stent coupled to the one way valve; an electrically activated pump for pumping fluids; and a power source for powering the pump.
摘要翻译：公开了一种用于体内流体控制的植入式动态泵装置。所述装置包括单向阀，所述阀可密封地展开在所述主体通道内并且设置有可展开的结构，所述展开结构包括联接到所述单向阀的至少一个可展开支架; 用于泵送流体的电激活泵; 以及为泵供电的电源。

7. 发明申请

WO2005034718A3 AMPLIFICATION-BASED CARDIAC ASSIST DEVICE 审中-公开
标题翻译：基于功率放大的心脏辅助装置
公开(公告)号：WO2005034718A3
公开(公告)日：2005-09-15
申请号：PCT/IL2004000950
申请日：2004-10-15
申请人： BAR ELI , ROUSSO BENNY , KORNOWSKI RAN
发明人： BAR ELI , ROUSSO BENNY , KORNOWSKI RAN
IPC分类号： A61B20060101 , A61M1/10
CPC分类号： A61M1/1058 , A61M1/1008 , A61M1/1055 , A61M1/1056 , A61M1/106 , A61M1/1068 , A61M1/1086 , A61M1/12 , A61M1/127 , A61M2205/33 , A61M2205/3303 , A61M2205/8243
摘要： Apparatus (20) is provided for compressing at least one ventricle of a heart (40). The apparatus includes a plurality of inflatable elements (64) and a pump (24) in fluid communication with the inflatable elements. At least one band (68) is in mechanical communication with the inflatable elements. A portion of the band is adapted to be placed around at least a portion of the heart in mechanical communication with the portion of the heart. The inflatable elements are arranged such that when the inflatable elements are inflated by the pump, the inflatable elements apply more force to the heart via shortening of the portion of the band than via expansion of the inflatable elements against the heart.
摘要翻译：提供用于压缩心脏（40）的至少一个心室的装置（20）。该装置包括多个可膨胀元件（64）和与可膨胀元件流体连通的泵（24）。至少一个带（68）与可充气元件机械连接。带的一部分适于围绕心脏的至少一部分与心脏的一部分机械连接。可膨胀元件布置成使得当可膨胀元件通过泵膨胀时，可膨胀元件通过缩短带的一部分而向心脏施加更大的力，而不是通过使可膨胀元件膨胀抵靠心脏。

8. 发明申请

WO02074189A2 METHOD AND APPARATUS OF IMPROVING MECHANICAL CHARACTERISTICS OF NONWOVEN MATERIALS 审中-公开
标题翻译：改善非金属材料机械特性的方法与装置
公开(公告)号：WO02074189A2
公开(公告)日：2002-09-26
申请号：PCT/IL0200218
申请日：2002-03-19
申请人： NICAST LTD , DUBSON ALEXANDER , BAR ELI
发明人： DUBSON ALEXANDER , BAR ELI
IPC分类号： A61F2/04 , A61F2/00 , A61F2/06 , A61L15/16 , A61L17/00 , A61L27/00 , A61L27/56 , B29C67/20 , C08F2/00 , D01D5/00 , D01D5/04 , D01D5/08 , D04H1/70 , D04H3/07 , D04H3/16 , A61F
CPC分类号： D04H3/16 , A61F2250/0023 , A61F2250/0067 , A61L27/56 , B29C67/20 , D01D5/0092 , D04H1/728 , D04H3/07
摘要： An apparatus for forming a nonwoven material from a liquefied polymer, the apparatus comprising: (a) a precipitation electrode;(b) a dispenser spaced apart from the precipitation electrode, and defining a first axis therebetween, the dispenser being at a first potential relative to the precipitation electrode; and (c) a system of electrodes being laterally displaced from the dispenser, being at a second potential relative to the precipitation electrode and capable of providing an electric field having at least one rotating component about the first axis; the dispenser and the system of electrodes being designed and constructed such that the liquefied polymer is dispensed from the dispenser and forms a plurality of entangled fibers moving in a direction of the precipitation electrode, hence forming the nonwoven material thereupon.
摘要翻译：一种用于从液化聚合物形成非织造材料的设备，所述设备包括：（a）沉淀电极;（b）与所述沉淀电极间隔开并且在其间限定第一轴线的分配器，所述分配器处于第一潜在相对位置到沉淀电极; 和（c）从分配器横向移位的电极系统，相对于沉淀电极处于第二电位，并且能够提供具有围绕第一轴线的至少一个旋转部件的电场; 分配器和电极系统被设计和构造成使得液体聚合物从分配器分配并且形成沿沉淀电极的方向移动的多个缠结纤维，从而在其上形成非织造材料。

9. 发明申请

WO2006126182A3 STENT APPARATUSES FOR TREATMENT VIA BODY LUMENS AND METHODS OF USE 审中-公开
标题翻译：用于通过身体照射治疗的STENT装置和使用方法
公开(公告)号：WO2006126182A3
公开(公告)日：2011-05-26
申请号：PCT/IB2006051874
申请日：2006-05-24
申请人： INSPIRE M D LTD , HOLZER ZEEV ASHER , PAZ OFIR , BAR ELI , COHEN ILANA
发明人： HOLZER ZEEV ASHER , PAZ OFIR , BAR ELI , COHEN ILANA
IPC分类号： A61F2/06
CPC分类号： A61F2/92 , A61F2/07 , A61F2/89 , A61F2/958 , A61F2002/075 , A61F2002/077 , A61F2230/0054 , A61F2230/0067 , A61F2250/0023 , A61F2250/0039 , A61L31/10 , A61L2300/20
摘要： An enhanced stent apparatus, comprising: a support element, wherein the support element is constructed to be positioned in a body lumen; and, a porous structure, the porous structure located on a surface of the support element, and wherein the porous structure is comprised of at least one fiber under 30 microns in diameter, has a coverage area of less than 30% and is provided with apertures.
摘要翻译：一种增强的支架装置，包括：支撑元件，其中所述支撑元件构造成定位在体腔中; 以及多孔结构，所述多孔结构位于所述支撑元件的表面上，并且其中所述多孔结构由至少一个直径在30微米以下的纤维构成，覆盖面积小于30％，并且设有孔。

10. 发明申请

WO2008047368A2 FILTER ASSEMBLIES 审中-公开
标题翻译：过滤器组件
公开(公告)号：WO2008047368A2
公开(公告)日：2008-04-24
申请号：PCT/IL2007001254
申请日：2007-10-18
申请人： INSPIREMD LTD , HOLZER ASHER , BAR ELI , PAZ OFIR
发明人： HOLZER ASHER , BAR ELI , PAZ OFIR
IPC分类号： A61F2/06
CPC分类号： A61F2/013 , A61F2002/018 , A61F2230/0006 , A61F2230/008
摘要： Disclosed is a filter assembly, comprising: a radially expandable vascular flow-increasing device, and a filter including an expandable proximal opening having an operative connection with the radially expandable vascular flow-increasing device, the proximal opening configured to expand in conjunction with expansion of the device, such that when the opening is in an expanded configuration, the filter is configured to filter debris from a fluid stream in which the filter is disposed.
摘要翻译：公开了一种过滤器组件，包括：径向可扩张的血管流量增加装置，以及包括具有与径向可膨胀的血管流量增加装置的可操作连接的可膨胀近端开口的过滤器，所述近端开口被配置成与使得当开口处于膨胀构型时，过滤器构造成从布置过滤器的流体流中过滤碎屑。

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