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    • 1. 发明申请
    • THE METHOD FOR MEASURING THE AMOUNT OF βiG-H3 PROTEIN AND DIAGNOSTIC KIT USING THE SAME
    • 测量βGG-H3蛋白和诊断试剂盒的方法
    • WO2003089935A1
    • 2003-10-30
    • PCT/KR2002/001975
    • 2002-10-22
    • REGEN BIOTECH, INC.KIM, In-SanBAE, Jong-Sub
    • KIM, In-SanBAE, Jong-Sub
    • G01N33/68
    • G01N33/6887G01N2333/78
    • The present invention relates to the method for measuring the amount of β ig-h3 protein and diagnostic kit using the same. Particularly, it relates to the method for measuring the amount of β ig-h3 protein in the body fluids by specific binding reaction between β ig-h3 protein or recombinant proteins of fas-1 domain in the β ig-h3 protein (including their fragments or their derivatives) and their ligands and relates to diagnostic kit for the renal diseases, hepatic diseases, rheumatoid arthritis or cardiovascular diseases comprising β ig-h3 protein or recombinant proteins of fas-1 domain in the β ig-h3 protein (including their fragments or their derivatives) and their ligands. The method and kit of the present invention can be effectively used as sensitive diagnostic method for the extent of damage or progress of the renal diseases, hepatic diseases, rheumatoid arthritis or cardiovascular diseases.
    • 本发明涉及测量βig-h3蛋白的量的方法及其使用的诊断试剂盒。 特别涉及通过βig-h3蛋白或βig-h3蛋白(包括它们的片段中的fas-1结构域的重组蛋白)之间的特异性结合反应来测量体液中βig-h3蛋白的量的方法 或其衍生物)及其配体,涉及包含βig-h3蛋白的肾脏疾病,肝脏疾病,类风湿性关节炎或心血管疾病的诊断试剂盒或βig-h3蛋白中​​的fas-1结构域的重组蛋白(包括其片段 或其衍生物)及其配体。 本发明的方法和试剂盒可以有效地用作肾脏疾病,肝脏疾病,类风湿性关节炎或心血管疾病的损伤或进展程度的敏感诊断方法。