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1. 发明申请

WO2012044121A3 SYSTEM FOR DIAGNOSING AVELLINO CORNEAL DYSTROPHY 审中-公开
标题翻译：用于诊断AVELLINO CORNEAL DYSTROPHY的系统
公开(公告)号：WO2012044121A3
公开(公告)日：2012-06-07
申请号：PCT/KR2011007272
申请日：2011-09-30
申请人： AVELLINO CO LTD , LEE GENE , YUN JUNG KUK
发明人： LEE GENE , YUN JUNG KUK
IPC分类号： A61B3/18
CPC分类号： C12Q1/686 , C12Q1/6883 , C12Q2600/156
摘要： The present invention relates to a system for diagnosing Avellino corneal dystrophy, and more particularly, to a system for diagnosing Avellino corneal dystrophy which determines normality or Avellino corneal dystrophy using a first inputted PCR-amplified value to a second PCR-amplified value ratio. The system for diagnosing Avellino corneal dystrophy according to the present invention enables more simple and accurate diagnosis regardless of the skill of a doctor. Particularly, the entire process of the system of the present invention is systemized to improve the accuracy of the diagnosis and enable the easy management of multiple patients to be tested.
摘要翻译：本发明涉及一种用于诊断阿维拉氏角膜营养不良的系统，更具体地，涉及一种用于诊断使用第一个输入的PCR扩增值至第二PCR扩增值比率的正常性或阿维拉氏角膜营养不良的Avellino角膜营养不良的系统。根据本发明的用于诊断Avellino角膜营养不良的系统使得能够更简单和准确地诊断，而不管医生的技能。特别地，本发明的系统的整个过程被系统化以提高诊断的准确性，并且能够容易地管理要测试的多个患者。

2. 发明申请

WO2012044121A2 SYSTEM FOR DIAGNOSING AVELLINO CORNEAL DYSTROPHY 审中-公开
标题翻译：系统诊断AVELLINO角膜营养不良
公开(公告)号：WO2012044121A2
公开(公告)日：2012-04-05
申请号：PCT/KR2011007272
申请日：2011-09-30
申请人： AVELLINO CO LTD , LEE GENE , YUN JUNG KUK
发明人： LEE GENE , YUN JUNG KUK
IPC分类号： A61B3/18
CPC分类号： C12Q1/686 , C12Q1/6883 , C12Q2600/156
摘要： The present invention relates to a system for diagnosing Avellino corneal dystrophy, and more particularly, to a system for diagnosing Avellino corneal dystrophy which determines normality or Avellino corneal dystrophy using a first inputted PCR-amplified value to a second PCR-amplified value ratio. The system for diagnosing Avellino corneal dystrophy according to the present invention enables more simple and accurate diagnosis regardless of the skill of a doctor. Particularly, the entire process of the system of the present invention is systemized to improve the accuracy of the diagnosis and enable the easy management of multiple patients to be tested.
摘要翻译：本发明涉及一种系统，用于诊断阿韦利诺角膜营养不良，并且更具体地，涉及一种系统，用于诊断阿韦利诺角膜营养不良使用第一输入的PCR扩增值到第二PCR扩增的值比其确定正常或阿韦利诺角膜营养不良。无论医生的技术如何，根据本发明的用于诊断阿韦利诺角膜营养不良的系统都能够实现更简单和准确的诊断。特别是，本发明的系统的整个过程被系统化以提高诊断的准确性，并使得能够容易地管理多个患者进行测试。

3. 发明申请

WO2011021846A2 MULTI-SPOT METAL-DEPOSITED NUCLEIC ACID CHIP WITH NANOSTRUCTURE ARRAYS FOR DIAGNOSING CORNEAL DYSTROPHY, AND METHOD FOR PRODUCING SAME 审中-公开
标题翻译：纳米结构阵列用于诊断角膜营养不良的多点金属沉积的核酸芯片及其制备方法
公开(公告)号：WO2011021846A2
公开(公告)日：2011-02-24
申请号：PCT/KR2010005452
申请日：2010-08-18
申请人： KOREA ADVANCED INST SCI & TECH , AVELLINO CO LTD , LEE SANG YUP , YOO SO YOUNG , KIM DO KYUN , PARK TAE JUNG , YUN JUNG KUK , LEE GENE
发明人： LEE SANG YUP , YOO SO YOUNG , KIM DO KYUN , PARK TAE JUNG , YUN JUNG KUK , LEE GENE
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6837 , B01J2219/00509 , B01J2219/00608 , B01J2219/00612 , B01J2219/00614 , B01J2219/00621 , B01J2219/00637 , B01J2219/00648 , B01J2219/00722 , B82Y30/00 , C12Q1/6883 , C12Q2600/158
摘要： The present invention relates to a multi-spot metal-deposited nucleic acid chip with nanostructure arrays for diagnosing corneal dystrophy, and more particularly, to a multi-spot metal-deposited nucleic acid chip with nanostructure arrays which uses the optical characteristics of localized surface plasmon resonance (LSPR), to a method for producing the chip, and to a multi-spot metal-deposited nucleic acid chip with nanostructure arrays for diagnosing BIGH3 gene mutations and various types of corneal dystrophies. According to the present invention, the metal-deposited nucleic acid chip with nanostructure arrays, and an analysis device including a light source, a detector, a spectrophotometer and a computer are combined to be used as a label-free biosensor based on the optical characteristics of LSPR. The multi-spot metal-deposited nucleic acid chip with nanostructure arrays for diagnosing BIGH3 gene mutations and corneal dystrophy according to the present invention diagnoses various types of corneal dystrophies, which are hereditary eye diseases, at the same time.
摘要翻译：具有纳米结构阵列的多点金属沉积核酸芯片技术领域本发明涉及用于诊断角膜营养不良的具有纳米结构阵列的多点金属沉积核酸芯片，并且更具体地涉及具有纳米结构阵列的多点金属沉积核酸芯片，其使用局部表面等离子体共振（LSPR），用于生产芯片的方法，以及具有纳米结构阵列的多点金属沉积核酸芯片，用于诊断BIGH3基因突变和各种类型的角膜营养不良。根据本发明，将具有纳米结构阵列的金属沉积核酸芯片和包括光源，检测器，分光光度计和计算机的分析装置组合以用作基于光学特性的无标记生物传感器的LSPR。根据本发明的用于诊断BIGH3基因突变和角膜营养不良的具有纳米结构阵列的多点金属沉积核酸芯片同时诊断作为遗传性眼病的各种类型的角膜营养不良。

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