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    • 2. 发明申请
    • TETRAHYDROISOQUINOLINE DERIVATIVES
    • 四氢喹啉衍生物
    • WO1998018763A1
    • 1998-05-07
    • PCT/JP1997003804
    • 1997-10-22
    • TANABE SEIYAKU CO., LTD.SUGITA, TakahisaOHNUKI, TetsuoYAMADA, MasakiTANAKA, SumikoNONAKA, NobuakiASAI, Yasuyuki
    • TANABE SEIYAKU CO., LTD.
    • C07D217/26
    • A61K31/472A61K31/4725A61K38/00C07D217/26C07K5/06078C07K5/06086C07K5/06139C07K5/06156C07K5/0821Y02P20/55
    • Medicinal compositions containing as the active ingredient compounds having an inhibitory effect on dipeptidyl-peptidase IV and having the tetrahydroisoquinoline skeleton, for example, tetrahydroisoquinoline derivatives represented by general formula (I) and the tetrahydroisoquinoline derivatives, wherein R represents (1) a group having the structure of an amino acid with optionally substituted amino from which the hydroxy atomic group in the carboxy atomic group has been eliminated, or (2) an amino protective group; R represents (1) optionally protected hydroxy, (2) having the structure of an amino acid with an optionally protected carboxy atomic group from which a hydrogen atom in the amino atomic group has been eliminated, or (3) a group having the stuctures of a primary or secondary amine or ammonia from which a hydrogen atom on the nitrogen atom has been eliminated; and R , R , R and R are the same or different and each represents hydrogen hydroxy or lower alkoxy.
    • 含有对二肽基肽酶IV具有抑制作用并具有四氢异喹啉骨架的活性成分化合物的药物组合物,例如由通式(I)表示的四氢异喹啉衍生物和四氢异喹啉衍生物,其中R 1表示(1)a 具有氨基酸结构的基团,其具有任选取代的氨基,羧基原子团中的羟基原子团已被除去,或(2)氨基保护基; R 2表示(1)任选被保护的羟基,(2)具有氨基酸结构的具有任选保护的羧基原子团的结构,氨基原子团中的氢原子从该氨基酸被除去,或(3)具有 原子或仲胺或氮原子上的氢原子已被除去的结构; R 3,R 4,R 5和R 6相同或不同,各自表示氢羟基或低级烷氧基。
    • 4. 发明申请
    • FEEDING APPARATUS AND RECORDING APPARATUS
    • 送料装置和记录装置
    • WO2011001660A4
    • 2011-11-10
    • PCT/JP2010004273
    • 2010-06-28
    • CANON KKASAI YASUYUKIEMOTO YUKI
    • ASAI YASUYUKIEMOTO YUKI
    • B65H3/06B65H1/26
    • B65H3/0607B65H1/266B65H2403/40B65H2407/21B65H2511/22
    • A feeding apparatus includes a pressing plate (21) movable up and down configured to allow recording media (P) to be stacked thereon, a feeding roller (41) configured to feed recording media stacked on the pressing plate, an urging unit (102) configured to urge the pressing plate in a direction to come close to the feeding roller, and a moving-away unit (121) configured to cause the pressing plate to move away from the feeding roller (41) against an urging force from the urging unit (102). The moving-away unit causes the pressing plate to move so that a distance between the uppermost recording medium being stacked and the feeding roller becomes approximately constant regardless of an amount of recording media stacked on the pressing plate.
    • 一种送料装置,包括可上下移动的压板(21),其配置为允许记录介质(P)堆叠在其上;馈送辊(41),被配置为供给堆叠在所述按压板上的记录介质,推压单元(102) 被配置为沿着靠近所述进给辊的方向推压所述压板;以及移动单元,其构造成使得所述压板抵抗来自所述推动单元的推动力而远离所述进给辊(41)移动, (102)。 移动单元使得压板移动,使得堆叠的最上面的记录介质和进给辊之间的距离不管堆叠在压板上的记录介质的量如何,都变得大致恒定。