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1. 发明申请

WO2010087873A2 RETRACTABLE INSTRUMENT HAVING A TWO STAGE PROTRACTION/RETRACTION SEQUENCE 审中-公开
标题翻译：具有两个阶段提取/延迟序列的可退回的仪器
公开(公告)号：WO2010087873A2
公开(公告)日：2010-08-05
申请号：PCT/US2009052419
申请日：2009-07-31
申请人： SANFORD LP , CHALLMAN ROBERT G , ARENAS JAIME
发明人： CHALLMAN ROBERT G , ARENAS JAIME
IPC分类号： B43K5/17
CPC分类号： B43K5/17 , B43K8/028
摘要： A retractable instrument in accordance with the disclosure advantageously has a simple construction and fewer pieces or sub-assemblies than known retractable instruments. The retractable instrument includes a barrel that encloses a tool holder. The tool holder has an extension, and a tool extending from the distal end of the extension. ? valve selectively covers the tool to protect the tool from environmental conditions. A biasing element is disposed between the valve and the tool holder, the biasing element biases the valve away from the tool holder. A movable closure assembly retains the valve on the extension and selectively allows the lid to open and close. The closure assembly includes a closure ring and a retention ring connected by one or more closure arms. The retention ring is disposed on the tool holder and the retention ring is prevented from sliding off of the tool holder by a retention stop.
摘要翻译：根据本公开的可伸缩器械有利地具有简单的结构，并且比已知的可伸缩器具更少的件或子组件。伸缩式仪器包括一个包围工具架的筒体。工具架具有延伸部和从延伸部的远端延伸的工具。？阀选择性地覆盖工具以保护工具免受环境条件的影响。偏置元件设置在阀和工具保持器之间，偏置元件将阀偏离刀架。可移动闭合组件将阀保持在延伸部上并且选择性地允许盖打开和关闭。闭合组件包括闭合环和通过一个或多个闭合臂连接的保持环。保持环设置在工具架上，并且通过保持止动件防止保持环从工具架滑出。

2. 发明申请

WO2010087873A3 RETRACTABLE INSTRUMENT HAVING A TWO STAGE PROTRACTION/RETRACTION SEQUENCE 审中-公开
公开(公告)号：WO2010087873A3
公开(公告)日：2010-08-05
申请号：PCT/US2009/052419
申请日：2009-07-31
申请人： SANFORD, L.P. , CHALLMAN, Robert, G. , ARENAS, Jaime
发明人： CHALLMAN, Robert, G. , ARENAS, Jaime
IPC分类号： B43K5/17
摘要： A retractable instrument in accordance with the disclosure advantageously has a simple construction and fewer pieces or sub -assemblies than known retractable instruments. The retractable instrument (10) includes a barrel (12) that encloses a tool holder. The tool holder has an extension, and a tool extending from the distal end of the extension. A valve (40) selectively covers the tool to protect the tool from environmental conditions. A biasing element (36) is disposed between the valve and the tool holder, the biasing element biases the valve away from the tool holder. A movable closure assembly (60) retains the valve on the extension and selectively allows the lid (42) to open and close. The closure assembly includes a closure ring (62) and a retention ring (64) connected by one or more closure arms (66). The retention ring is disposed on the tool holder and the retention ring is prevented from sliding off of the tool holder by a retention stop (32).

3. 发明申请

WO2005119255A3 CONSTRAINED CIS-DIOL-BORATE BIOCONJUGATION SYSTEM 审中-公开
标题翻译：受约束的二硼酸盐生物量化系统
公开(公告)号：WO2005119255A3
公开(公告)日：2007-03-01
申请号：PCT/US2005016508
申请日：2005-05-11
申请人： APPLERA CORP , BAGGIO RICKY F , SPARKS ALISON L , JUO ROUH-RONG , ARENAS JAIME F
发明人： BAGGIO RICKY F , SPARKS ALISON L , JUO ROUH-RONG , ARENAS JAIME F
IPC分类号： A61K47/48 , C07H21/04 , C07K14/47 , C12Q1/68 , G01N33/53 , G01N33/543
CPC分类号： B82Y30/00 , A61K47/54 , C07H21/04 , G01N33/54353 , Y10S530/812
摘要： The invention pertains to bioconjugation systems comprising sterically constrained cis -diols and borates.
摘要翻译：本发明涉及包含空间受限的顺式二醇和硼酸盐的生物共轭体系。

4. 发明申请

WO2008089138A3 VALVE MADE FROM TWO MATERIALS AND WRITING UTENSIL WITH RETRACTABLE TIP INCORPORATING SAME 审中-公开
公开(公告)号：WO2008089138A3
公开(公告)日：2008-07-24
申请号：PCT/US2008/050998
申请日：2008-01-14
申请人： SANFORD, L.P. , HAYES, Christopher, John , BIELECKI, Andrew , ARENAS, Jaime
发明人： HAYES, Christopher, John , BIELECKI, Andrew , ARENAS, Jaime
IPC分类号： B43K8/02
摘要： A valve (44) includes a first valve portion made from a first material, the first valve portion including a body (26), a door (64), and an inner hinge (112) pivotably connecting the body to the door, the body including a first opening at a first end and a second opening at a second end opposite the first end, and a circumferential recess disposed in the second end, wherein the inner hinge pivotably connects the door to the body at the first end and a second valve portion made from a second material, the second valve portion including an inner seal disposed in the circumferential recess, the inner seal including a circumferential ridge extending inwardly, the second valve portion further including a door seal disposed on the first end of the body.

5. 发明申请

WO2004082962A2 WRITING INSTRUMENT WITH A SHEET MATERIAL DISPENSER 审中-公开
标题翻译：书写材料分配器
公开(公告)号：WO2004082962A2
公开(公告)日：2004-09-30
申请号：PCT/US2004008490
申请日：2004-03-18
申请人： SANFORD LP , ERLEBACHER JACQUELINE , BIELECKI ANDREW , JACOBS BARRY H , ARENAS JAIME , FURLONG BRIAN DOUGLAS , SMITH DANNY R JR
发明人： ERLEBACHER JACQUELINE , BIELECKI ANDREW , JACOBS BARRY H , ARENAS JAIME , FURLONG BRIAN DOUGLAS , SMITH DANNY R JR
IPC分类号： B42D5/00 , B43K20060101 , B43K29/00 , B43K29/12 , B43K29/20 , B65H1/04 , B65H16/02 , B65H35/00 , B43K
CPC分类号： B43K29/12 , B43K29/20
摘要： Disclosed herein are writing instruments with tape flag dispensers. In one of the various embodiments, a writing instrument has a body portion, a writing tip, and a flag dispenser that can be attached to and detached from the body portion. The flag dispenser holds a supply of tape flags, such as a folded stack of tape flags, which can be removed through an opening in the dispenser. The flag dispenser can be, for example, a cap that covers the writing tip or an attachment that affixes to an end off the body portion. In another embodiment, a writing instrument has a body portion, a writing tip, a flag dispenser integrally incorporated into the body portion, a containing section housed in the flag dispenser, and an opening in the containing section through which tape flags can be issued.
摘要翻译：这里公开的是用磁带标记分配器书写工具。在各种实施例中的一个中，书写工具具有主体部分，书写尖端和可以附接到主体部分并从主体部分拆卸的标志分配器。标记分配器保持供应的带状标记，例如可以通过分配器中的开口移除的折叠的带状标签。标记分配器可以是例如覆盖书写尖端的帽或附接到身体部分的一端的附件。在另一个实施例中，书写工具具有主体部分，书写尖端，整体结合到主体部分中的标记分配器，容纳在标记分配器中的容纳部分，以及容纳部分中可以发出磁带标记的开口。

6. 发明申请

WO2009033056A1 REUSABLE DETECTION SURFACES AND METHODS OF USING SAME 审中-公开
标题翻译：可重复使用的检测表面及其使用方法
公开(公告)号：WO2009033056A1
公开(公告)日：2009-03-12
申请号：PCT/US2008/075448
申请日：2008-09-05
申请人： BIOSCALE, INC. , ARENAS, Jaime, E. , CHOI, Hyun-Goo , DICKERSON, William, Matthew , HEMBREE, Sarah, Beth , MADISON, Lara, Louise , MASTERS, Brett, P. , MILLER, Michael, F. , WANG, Wayne, U.
发明人： ARENAS, Jaime, E. , CHOI, Hyun-Goo , DICKERSON, William, Matthew , HEMBREE, Sarah, Beth , MADISON, Lara, Louise , MASTERS, Brett, P. , MILLER, Michael, F. , WANG, Wayne, U.
IPC分类号： G01N33/543 , G01N29/02
CPC分类号： G01N29/022 , B01L9/52 , G01N33/54373 , G01N2291/014 , G01N2291/0255 , G01N2291/0256 , G01N2291/02809 , G01N2291/02836 , G01N2291/0427
摘要： The technology provided herein generally relates to reusable detection surfaces and methods for reusing a detection surface after using the detection surface in an assay for an analyte. In particular, the present application relates to a detection surface of an acoustic device, like flexural plate wave (FPW) device, wherein a first capture agent capable of binding an analyte is linked to the detection surface and remains linked to the detection surface upon removal of the bound analyte by chemical wash. Thus the detection surface can be reused in further assays. Furthermore the application claims a kit and a reusable cartridge with a fluid chamber, an acoustic device with detection surface and a first capturing agent.
摘要翻译：本文提供的技术通常涉及可重复使用的检测表面和用于在分析物的测定中使用检测表面后重新使用检测表面的方法。特别地，本申请涉及一种声学装置的检测表面，例如弯曲板波（FPW）装置，其中能够将分析物结合的第一捕获剂与检测表面连接，并且在去除时保持与检测表面的连接的化学洗涤结合的分析物。因此，检测表面可以再次用于进一步的检测。此外，本申请要求具有流体室的套件和可重复使用的盒，具有检测表面的声学装置和第一捕获剂。

7. 发明申请

WO2008089138A2 VALVE MADE FROM TWO MATERIALS AND WRITING UTENSIL WITH RETRACTABLE TIP INCORPORATING SAME 审中-公开
标题翻译：从两种材料制成的阀门，并将UTENSIL与可复制的烙铁头相符
公开(公告)号：WO2008089138A2
公开(公告)日：2008-07-24
申请号：PCT/US2008050998
申请日：2008-01-14
申请人： SANFORD LP , HAYES CHRISTOPHER JOHN , BIELECKI ANDREW , ARENAS JAIME
发明人： HAYES CHRISTOPHER JOHN , BIELECKI ANDREW , ARENAS JAIME
CPC分类号： B43K8/028 , B43K8/04 , B43K24/08
摘要： A valve includes a first valve portion made from a first material, the first valve portion including a body, a door, and an inner hinge pivotably connecting the body to the door, the body including a first opening at a first end and a second opening at a second end opposite the first end, and a circumferential recess disposed in the second end, wherein the inner hinge pivotably connects the door to the body at the first end and a second valve portion made from a second material, the second valve portion including an inner seal disposed in the circumferential recess, the inner seal including a circumferential ridge extending inwardly, the second valve portion further including a door seal disposed on the first end of the body.
摘要翻译：阀包括由第一材料制成的第一阀部分，第一阀部分包括主体，门和可铰接地将主体连接到门的内铰链，主体包括在第一端处的第一开口和第二开口在与所述第一端相对的第二端和设置在所述第二端的周向凹部，其中所述内铰链在所述第一端处可枢转地将所述门与所述主体连接，以及由第二材料制成的第二阀部分，所述第二阀部分包括设置在所述周向凹部中的内部密封件，所述内部密封件包括向内延伸的周向凸缘，所述第二阀部分还包括设置在所述主体的第一端上的门密封件。

8. 发明申请

WO2005119255A2 CONSTRAINED CIS-DIOL-BORATE BIOCONJUGATION SYSTEM 审中-公开
标题翻译：受约束的二硼酸盐生物量化系统
公开(公告)号：WO2005119255A2
公开(公告)日：2005-12-15
申请号：PCT/US2005/016508
申请日：2005-05-11
申请人： APPLERA CORPORATION , BAGGIO, Ricky, F. , SPARKS, Alison, L. , JUO, Rouh-Rong , ARENAS, Jaime, F.
发明人： BAGGIO, Ricky, F. , SPARKS, Alison, L. , JUO, Rouh-Rong , ARENAS, Jaime, F.
IPC分类号： G01N33/53
CPC分类号： B82Y30/00 , A61K47/54 , C07H21/04 , G01N33/54353 , Y10S530/812
摘要： The invention pertains to bioconjugation systems comprising sterically constrained cis -diols and borates.
摘要翻译：本发明涉及包含空间受限顺式 - 二醇和硼酸盐的生物共轭体系。

9. 发明申请

WO2004082962A3 WRITING INSTRUMENT WITH A REMOVABLE SHEET MATERIAL DISPENSER 审中-公开
公开(公告)号：WO2004082962A3
公开(公告)日：2004-09-30
申请号：PCT/US2004/008490
申请日：2004-03-18
申请人： SANFORD, L.P. , ERLEBACHER, Jacqueline , BIELECKI, Andrew , JACOBS, Barry, H. , ARENAS, Jaime , FURLONG, Brian, Douglas , SMITH, Danny, R., Jr.
发明人： ERLEBACHER, Jacqueline , BIELECKI, Andrew , JACOBS, Barry, H. , ARENAS, Jaime , FURLONG, Brian, Douglas , SMITH, Danny, R., Jr.
IPC分类号： B43K29/12
摘要： Disclosed herein are writing instruments (100, 200…) with tape flag dispensers. In one of the various embodiments, a writing instrument has a body portion (110, 210…), a writing tip (150), and a flag dispenser (120, 230…) that can be attached to and detached from the body portion. The flag dispenser holds a supply of tape flags (190, 290…), such as a folded stack of tape flags, which can be removed through an opening (175, 275…) in the dispenser. The flag dispenser can be, for example, a cap (120, 220…) that covers the writing tip or an attachment that affixes to an end off the body portion. In another embodiment, a writing instrument has a body portion, a writing tip, a flag dispenser integrally incorporated into the body portion, a containing section housed in the flag dispenser, and an opening in the containing section through which tape flags can be issued.

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