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1. 发明申请

WO2008007377A3 COMPRESSION ASSEMBLIES AND APPLICATORS FOR USE THEREWITH 审中-公开
公开(公告)号：WO2008007377A3
公开(公告)日：2008-01-17
申请号：PCT/IL2007/000878
申请日：2007-07-12
申请人： NITI SURGICAL SOLUTIONS LTD. , HARARI, Boaz , MONASSEVITCH, Leonid , ARAD, Michael , KOPELMAN, Doron , PERLE, Amir , SHENHAV, Boaz , GREENBERG, Kobby
发明人： HARARI, Boaz , MONASSEVITCH, Leonid , ARAD, Michael , KOPELMAN, Doron , PERLE, Amir , SHENHAV, Boaz , GREENBERG, Kobby
IPC分类号： B31B1/00 , A61B17/04 , A61B17/08
摘要： A compression assembly for use in compressing tissue comprising a first portion which includes a first compression element and a second portion which comprises a second compression element, at least one support element, and at least one spring element. Typically the spring element is formed of a shape-memory material. The at least one spring element is in compressive force contact with the second compression element and the tissue to be joined is positioned between the first and second compression elements. A plurality of needles on one of the support elements is operative to pierce the tissue and the first portion of the assembly, holding the first compression element to the second portion of the assembly. The invention is appropriate for joining severed tissue in anastomosis procedures or closing natural or surgically produced tissue perforations.

2. 发明申请

WO2008007377A2 COMPRESSION ASSEMBLIES AND APPLICATORS FOR USE THEREWITH 审中-公开
标题翻译：压缩机组及其使用者
公开(公告)号：WO2008007377A2
公开(公告)日：2008-01-17
申请号：PCT/IL2007000878
申请日：2007-07-12
申请人： NITI MEDICAL TECHNOLOGIES LTD , HARARI BOAZ , MONASSEVITCH LEONID , ARAD MICHAEL , KOPELMAN DORON , PERLE AMIR , SHENHAV BOAZ , GREENBERG KOBBY
发明人： HARARI BOAZ , MONASSEVITCH LEONID , ARAD MICHAEL , KOPELMAN DORON , PERLE AMIR , SHENHAV BOAZ , GREENBERG KOBBY
IPC分类号： A61B17/08
CPC分类号： A61B17/115 , A61B17/0643 , A61B17/1114 , A61B17/1152 , A61B17/32053 , A61B2017/0641 , A61B2017/2939
摘要： A compression assembly for use in compressing tissue comprising a first portion which includes a first compression element and a second portion which comprises a second compression element, at least one support element, and at least one spring element. Typically the spring element is formed of a shape-memory material. The at least one spring element is in compressive force contact with the second compression element and the tissue to be joined is positioned between the first and second compression elements. A plurality of needles on one of the support elements is operative to pierce the tissue and the first portion of the assembly, holding the first compression element to the second portion of the assembly. The invention is appropriate for joining severed tissue in anastomosis procedures or closing natural or surgically produced tissue perforations.
摘要翻译：一种用于压缩组织的压缩组件，包括包括第一压缩元件的第一部分和包括第二压缩元件，至少一个支撑元件和至少一个弹簧元件的第二部分。通常弹簧元件由形状记忆材料形成。所述至少一个弹簧元件与所述第二压缩元件压缩接触，并且待连接的组织位于所述第一和第二压缩元件之间。一个支撑元件上的多个针可操作以刺穿组织和组件的第一部分，将第一压缩元件保持在组件的第二部分。本发明适用于在吻合过程中连接切断的组织或闭合天然或手术产生的组织穿孔。

3. 发明申请

WO0219888A3 STAPLES FOR BONE FIXATION 审中-公开
标题翻译：用于骨骼固定的钉子
公开(公告)号：WO0219888A3
公开(公告)日：2002-10-17
申请号：PCT/IL0100841
申请日：2001-09-06
申请人： NITI ALLOYS TECH LTD , MONASSEVITCH LEONID , ARAD MICHAEL , LASTER ZVI
发明人： MONASSEVITCH LEONID , ARAD MICHAEL , LASTER ZVI
IPC分类号： A61B17/00 , A61B17/064 , A61B17/068 , A61B17/84
CPC分类号： A61B17/0682 , A61B17/0642 , A61B2017/00867 , Y10S606/911 , Y10S606/916
摘要： A bone staple (10), formed of shape-memory alloy, and apparatus (60, 90, 100, 140) for deforming the staple (10) to simultaneously facilitate its insertion into the bone and increase its length span to a desired value, a deformation applied by the apparatus (60, 90, 100, 140) being maintained within an allowable range to insure that the staple (10) will resume its austenitic shape upon transformation to the austenitic phase.
摘要翻译：由形状记忆合金形成的骨钉（10）和用于使钉（10）变形的装置（60,90,100,140）同时促进其插入骨并将其长度跨度增加至期望值，由装置（60,90,100,140）施加的变形保持在允许范围内，以确保在转变成奥氏体相时，钉（10）将恢复其奥氏体形状。

4. 发明申请

WO2008081436A3 TISSUE COMPRESSION USING SURGICAL CLIPS 审中-公开
公开(公告)号：WO2008081436A3
公开(公告)日：2008-07-10
申请号：PCT/IL2007/001619
申请日：2007-12-27
申请人： NITI SURGICAL SOLUTIONS LTD. , MONASSEVITCH, Leonid , SHENHAV, Boaz , HARARI, Boaz , PERLE, Amir , ARAD, Michael , MILLIS, Shahar , GREENBERG, Kobby , GELLER, Alex , SZOLD, Amir , LELCUK, Shlomo , KOPELMAN, Doron , BAPAYE, Amol , ROSNER, Dror
发明人： MONASSEVITCH, Leonid , SHENHAV, Boaz , HARARI, Boaz , PERLE, Amir , ARAD, Michael , MILLIS, Shahar , GREENBERG, Kobby , GELLER, Alex , SZOLD, Amir , LELCUK, Shlomo , KOPELMAN, Doron , BAPAYE, Amol , ROSNER, Dror
IPC分类号： A61B17/04 , A61B1/00
摘要： A compression clip system where compression is used to close a tissue opening, reduce the volume of an organ, ligate dilated blood vessels, or compress tissue adjacent to various other types of lesions to induce healing. Compression prevents bleeding and the leakage of body fluids into a body cavity. The opening may be surgery-induced as in gastrectomies or formed naturally such as peptic ulcers and hemorrhoids. The system (150) may include a compression clip (10), a suitable clip applier (30), a grasper assembly (260 and an endoscope (300) all brought to the compression site via a multi-lumen sleeve (150).

5. 发明申请

WO2007141777A2 PALM SIZE SURGICAL STAPLER FOR SINGLE HAND OPERATION 审中-公开
标题翻译： PALM SIZE手术台单手操作
公开(公告)号：WO2007141777A2
公开(公告)日：2007-12-13
申请号：PCT/IL2007000673
申请日：2007-06-03
申请人： NITI MEDICAL TECHNOLOGIES LTD , ARAD MICHAEL , HARARI BOAZ , PERLE AMIR , ROSNER DROR
发明人： ARAD MICHAEL , HARARI BOAZ , PERLE AMIR , ROSNER DROR
IPC分类号： A61B17/04
CPC分类号： A61B17/07207 , A61B2017/07214 , A61B2017/07228 , A61B2017/07264 , A61B2017/2922 , A61B2017/2923 , A61B2090/061
摘要： Palm-size staplers for surgical procedures are proposed. The staplers include cartridge and slider assemblies with the cartridge assembly containing staples. As the slider assembly advances step-wise incrementally it provides a staple ejection force causing ejection of staples. Optionally, a blade element may be included for cutting. An anvil member is operable in closed and open positions with respect to the cartridge assembly. When in a closed position, the anvil member holds a portion of tissue against the cartridge assembly, ejected staples passing through the held tissue. Actuation of the staplers is effected by a lever member. A locking mechanism, when in its locked position, holds the anvil member adjacent to the cartridge assembly allowing closure of the staple to occur. The devices are intended for one hand use.
摘要翻译：提出了用于外科手术的掌上型订书机。订书机包括盒和滑块组件，其中盒组件包含订书钉。当滑块组件递增地逐步地前进时，它提供引起钉钉排出的缝钉排出力。可选地，可以包括刀片元件用于切割。砧构件可相对于盒组件在闭合和打开位置操作。当处于关闭位置时，砧座构件将组织的一部分保持抵靠盒组件，从而喷射经过保持的组织的钉。订书机的致动由杠杆构件实现。当处于其锁定位置时，锁定机构将砧座构件保持在与盒组件相邻的位置，从而允许缝合钉发生。这些设备用于一次性使用。

6. 发明申请

WO2004008937A2 IMPROVED INTUSSUSCEPTION AND ANASTOMOSIS APPARATUS 审中-公开
标题翻译：改进的内分泌和解剖设备
公开(公告)号：WO2004008937A2
公开(公告)日：2004-01-29
申请号：PCT/IL0300597
申请日：2003-07-21
申请人： NITI MEDICAL TECHNOLOGIES LTD , MONASSEVITCH LEONID , SPENSER BENJAMIN , ARAD MICHAEL , NE EMAN RONEN
发明人： MONASSEVITCH LEONID , SPENSER BENJAMIN , ARAD MICHAEL , NE EMAN RONEN
IPC分类号： A61B17/115 , A61B17/00 , A61B17/064 , A61B17/08 , A61B17/11 , A61B
CPC分类号： A61B17/0643 , A61B17/1114 , A61B2017/00867 , A61B2017/1117 , A61B2017/1132
摘要： Apparatus for intratubular intussusception and anastomosis of a hollow organ portion including a cylindrical enclosure, coaxial intratubular intussusception device, for intussusception and clamping means. The apparatus also includes an intratubular anastomosis apparatus for joining organ portions after intussusception thereof with an anastomosis ring and crimping support element. The ring is formed of a shape memory alloy wire, for crimping adjacent organ portions against the crimping support element so as to cause anastomosis therebetween. The ring assumes a plastic or malleable state, at a lower temperature and an elastic state at a higher temperature. The apparatus further includes the crimping support element for intratubular insertion so as to provide a support for crimping the organ portions against the support element. The apparatus additionally includes a surgical excising means, for excising an intussuscepted organ portion, after crimping adjacent intussuscepted organ walls against the crimping support element with the anastomosis ring.
摘要翻译：用于腔内肠套叠和中空器官部分吻合的装置，包括圆柱形外壳，同轴的管内肠套叠装置，用于套叠和夹紧装置。该装置还包括用于在肠套叠后的器官部分与吻合环和压接支撑元件接合的管状内吻合装置。环由形状记忆合金线形成，用于将相邻的器官部分压靠在压接支撑元件上，从而在其间进行吻合。环在较低的温度和较高的温度下呈弹性状态呈现塑性或延展性状态。该装置还包括用于颈内插入的压接支撑元件，以便提供用于将器官部分压靠支撑元件的支撑。该装置还包括手术切除装置，用于在用吻合环将相邻的套叠器官壁压靠在卷曲支撑元件上之后切除肠套叠器官部分。

7. 发明申请

WO2003101311A1 SURGICAL CLIP APPLICATOR DEVICE 审中-公开
标题翻译：手术夹施加器装置
公开(公告)号：WO2003101311A1
公开(公告)日：2003-12-11
申请号：PCT/IL2003/000398
申请日：2003-05-15
申请人： NITI MEDICAL TECHNOLOGIES LTD. , MONASSEVITCH, Leonid , LELCUK, Shlomo , ARAD, Michael , HARARI, Boaz , NEEMAN, Ronen
发明人： MONASSEVITCH, Leonid , LELCUK, Shlomo , ARAD, Michael , HARARI, Boaz , NEEMAN, Ronen
IPC分类号： A61B17/08
CPC分类号： A61B17/128 , A61B17/064 , A61B17/0643 , A61B17/0644 , A61B17/083 , A61B17/11 , A61B17/1114 , A61B17/1227 , A61B17/2812 , A61B17/32 , A61B2017/00867 , A61B2017/0649 , A61B2017/1107 , A61B2017/1125 , A61B2017/1139 , A61B2017/1225
摘要： The present invention, discloses an anastomosis clip applicator device (134) for applying a surgical clip (12), formed at least partly of a shape memory alloy, to press together adjacent wall portions of adjacent hollow organ portions so as to effect anastomosis therebetween. The applicator device (134) includes: gripping apparatus for gripping a surgical clip (12), a release mechanism, associated with the gripping apparatus, and tissue cutting apparatus (124), operatively associated with the gripping apparatus. There is also apparatus for activating the gripping apparatus, the release mechanism and the cutting apparatus, so as to introduce and apply the surgical clip (12) into adjacent hollow organ portions, such that the surgical clip (12) compresses together the adjacent walls of the hollow organ portions, and thereafter causes the cutting apparatus (124) to perforate the adjacent pressed together organ walls to provide patency through the joined portions of the hollow organ.
摘要翻译：本发明公开了一种用于施加至少部分由形状记忆合金形成的外科夹子（12）的吻合夹施加器装置（134），将邻近的中空器官部分的相邻壁部分压在一起，以便在它们之间进行吻合。施用装置（134）包括：用于夹持与夹持装置相关联的手术夹子（12），释放机构的夹持装置和与夹持装置可操作地相关联的组织切割装置（124）。还有用于启动夹持装置，释放机构和切割装置的装置，以将手术夹子（12）引入并施加到相邻的中空器官部分中，使得手术夹子（12）将相邻的壁中空器官部分，然后使切割设备（124）穿过相邻的压制在一起的器官壁，以通过中空器官的接合部分提供通畅。

8. 发明申请

WO2011086551A1 GASTRIC ABLATION DEVICE 审中-公开
标题翻译：胃收缩装置
公开(公告)号：WO2011086551A1
公开(公告)日：2011-07-21
申请号：PCT/IL2011/000037
申请日：2011-01-12
申请人： SZOLD, Amir , ARAD, Michael
发明人： SZOLD, Amir , ARAD, Michael
IPC分类号： A61B18/18 , A61N1/00
CPC分类号： A61B18/1492 , A61B18/1477 , A61B18/1815 , A61B2018/0022 , A61B2018/00494 , A61B2018/1425
摘要： A device and method for creating a reduction in gastric volume by selective ablation of parts of the stomach wall. Unlike prior art methods, no attempt is made to keep the mucosa at the treated region intact, and the ablated region of the stomach is meant to be disfunctional after treatment. An inert sleeve, preferably an inflatable balloon, is positioned such that it lies along the lesser curvature wall of the stomach and preferably in contact therewith. The sleeve has at least one deployable protuberance, extending towards the greater curvature wall of the stomach wall. The protrusion is deployed only when the sleeve is in its predetermined position. This protrusion has ablation elements, such as RF electrodes, to ablate the stomach wall in proximity to the elements, without affecting the wall beneath the sleeve. After treatment, the ablated area undergoes necrosis and shrinks away, leaving the sleeved area intact.
摘要翻译：一种用于通过胃壁部分的选择性消融来产生胃体积减少的装置和方法。不同于现有技术的方法，没有尝试将粘膜保持在处理区域完整，并且胃的烧蚀区域意味着在治疗后失去功能。惰性套管，优选可膨胀的气囊被定位成使得其沿着胃的较小弯曲壁布置并且优选地与胃接触。套筒具有至少一个可展开的突起，朝向胃壁的较大曲率壁延伸。仅当套筒处于其预定位置时才突出突起。该突起具有消融元件，例如RF电极，以消除靠近元件的胃壁，而不影响套筒下方的壁。治疗后，烧伤区域发生坏死并收缩，使套管区域完好无损。

9. 发明申请

WO2008104982A3 CONTROL OF THE INTAKE OF UNDESIRED SUBSTANCES 审中-公开
标题翻译：控制不饱和物质的摄入
公开(公告)号：WO2008104982A3
公开(公告)日：2010-02-18
申请号：PCT/IL2008000257
申请日：2008-02-28
申请人： STIMPULSE LTD , ARAD MICHAEL , LASTER ZVI
发明人： ARAD MICHAEL , LASTER ZVI
IPC分类号： A61B5/05
CPC分类号： A61B5/228 , A61B5/14532 , A61B5/4205 , A61N1/0517 , A61N1/0548 , A61N1/36007
摘要： A system for controlling the intake of food or drink, incorporating sensors to detect parameters relating to the subject's chewing or swallowing actions. The sensor signals are input to a controller which may activate stimulating electrodes implanted into the deglutition or mastication muscles, thereby controlling the ability of the subject to continue chewing or swallowing. Alternatively, the stimulating electrodes may be implanted in the Gastro-intestinal system to induce a feeling of nausea or satiety. The parameters may be related to the quantity of food, the type of food, the length of time of the intake, the time of day of the intake, the elapsed time since the previous intake, or any other parameter used to characterize the intake's caloric effect on the subject. Adaptations of the system and method may be used to control the intake of harmful or forbidden substances, such as alcohol, drugs or tobacco.
摘要翻译：一种用于控制食物或饮料摄入的系统，包括用于检测与受试者咀嚼或吞咽作用相关的参数的传感器。传感器信号被输入到控制器，该控制器可以激活植入到吞咽或咀嚼肌肉中的刺激电极，从而控制受试者继续咀嚼或吞咽的能力。或者，刺激电极可以植入胃肠系统以诱导恶心或饱腹感。这些参数可能与食物的数量，食物的类型，摄入时间的长度，摄入日的时间，从上次摄取以来的经过时间或用于表征摄入量的任何其它参数对主题的影响。系统和方法的适应可用于控制有害或禁止物质（如酒精，药物或烟草）的摄入。

10. 发明申请

WO2008081436A2 TISSUE COMPRESSION USING SURGICAL CLIPS 审中-公开
标题翻译：使用手术夹的组织压缩
公开(公告)号：WO2008081436A2
公开(公告)日：2008-07-10
申请号：PCT/IL2007001619
申请日：2007-12-27
申请人： NITI MEDICAL TECHNOLOGIES LTD , MONASSEVITCH LEONID , SHENHAV BOAZ , HARARI BOAZ , PERLE AMIR , ARAD MICHAEL , MILLIS SHAHAR , GREENBERG KOBBY , GELLER ALEX , SZOLD AMIR , LELCUK SHLOMO , KOPELMAN DORON , BAPAYE AMOL , ROSNER DROR
发明人： MONASSEVITCH LEONID , SHENHAV BOAZ , HARARI BOAZ , PERLE AMIR , ARAD MICHAEL , MILLIS SHAHAR , GREENBERG KOBBY , GELLER ALEX , SZOLD AMIR , LELCUK SHLOMO , KOPELMAN DORON , BAPAYE AMOL , ROSNER DROR
IPC分类号： A61B1/00
CPC分类号： A61B1/018 , A61B17/0643 , A61B17/12 , A61B17/122 , A61B17/1227 , A61B17/1285 , A61B2017/0641 , A61B2017/2927 , A61B2017/308
摘要： A compression clip system where compression is used to close a tissue opening, reduce the volume of an organ, ligate dilated blood vessels or compress tissue adjacent to various other types of lesions to induce healing. Compression prevents bleeding and the leakage of body fluids into a body cavity. The opening may be surgery induced as in gastrectomies or formed naturally such as peptic ulcers and hemorrhoids. The system may include a compression clip, a suitable clip applier, a grasper assembly and an endoscope all brought to the compression site via a multi-lumen sleeve.
摘要翻译：压缩夹系统，其中压缩用于封闭组织开口，减少器官的体积，连接扩张的血管或压迫与各种其它类型的损伤相邻的组织以诱导愈合。压缩防止体液流入体腔的出血和泄漏。开口可以是胃切除手术或自然形成的手术，如消化性溃疡和痔疮。该系统可以包括压缩夹，合适的施夹器，抓紧器组件和内窥镜，其全部通过多腔套筒带到压缩部位。

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