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1. 发明申请

WO2022010665A1 MIXER FOR LIQUID CHROMATOGRAPHY 审中-公开
公开(公告)号：WO2022010665A1
公开(公告)日：2022-01-13
申请号：PCT/US2021/039058
申请日：2021-06-25
申请人： WATERS TECHNOLOGIES CORPORATION
发明人： GRITTI, Fabrice
IPC分类号： G01N30/34
摘要： Described is a mixer 50 for a liquid chromatography system. The mixer includes a flow distributor 52, a mixing disk 54 and a flow collector 56. The mixer includes an inlet face, an outlet face and a plurality of channels each having an inlet end at the inlet face and an outlet end at the outlet face. The channels have a flow direction anisotropy between the inlet and outlet faces. A compositional solvent stream received at the flow distributor 52 is distributed across the inlet face of the mixing disk 54 and the flow collector 56 collects the distributed solvent composition stream after passing through the mixing disk 54. The mixing disk 54 may include a dispersive medium having a random porous structure. A retention time distribution of the mixer may depend on the structure of the channels between the inlet and outlet faces of the mixing disk.

2. 发明申请

WO2020040875A1 MULTIPLE SAMPLE DIFFERENTIAL SCANNING CALORIMETER 审中-公开
公开(公告)号：WO2020040875A1
公开(公告)日：2020-02-27
申请号：PCT/US2019/039474
申请日：2019-06-27
申请人： WATERS TECHNOLOGIES CORPORATION
发明人： DANLEY, Robert L.
IPC分类号： G01N25/48 , G01K17/04
摘要： A heat flow rate measurement method for use with a differential scanning calorimeter sensor (100) is provided. The method includes calculating a heat exchange between a plurality of sample containers and a reference container placed on a plurality of sample calorimeter units (3, 4, 5) and a reference calorimeter unit (2), respectively, and determining a heat flow rate of samples within the sample containers using the calculated heat exchange between the plurality of sample containers and the reference container. A multiple sample differential scanning calorimeter sensor and calorimeter system are also provided.

3. 发明申请

WO2019160610A1 ACOUSTIC NOISE REDUCTION AUDIO SYSTEM HAVING TAP CONTROL 审中-公开
公开(公告)号：WO2019160610A1
公开(公告)日：2019-08-22
申请号：PCT/US2018/067582
申请日：2018-12-27
申请人： BOSE CORPORATION
发明人： YAMKOVOY, Paul
IPC分类号： G10K11/178 , H04R1/10
摘要： An acoustic noise reduction (ANR) headphone described herein has current detection circuitry that detects current consumed by an acoustic driver amplifier as a result of pressure changes due to a tapping of the headphone. Tapping may be performed to change an audio feature or operating mode of the audio system for the headphone. The current detection circuitry senses a characteristic of the current consumed by the acoustic driver amplifier that can be used to determine an occurrence of a tap event. Examples of a characteristic include an amplitude, waveform or duration of the sensed current. Advantageously, the ANR headphones avoid the need for control buttons to initiate the desired changes to the audio feature or operating mode.

4. 发明申请

WO2019050699A2 FLUID MIXER 审中-公开
公开(公告)号：WO2019050699A2
公开(公告)日：2019-03-14
申请号：PCT/US2018/047904
申请日：2018-09-05
申请人： WATERS TECHNOLOGIES CORPORATION
发明人： MACKINNON, Peter , JACKSON, Michael, R.
摘要： A fluid mixer includes a flow splitter and a mixing chamber. The flow splitter includes an inlet for receiving a flow of fluid and is configured to split the flow of fluid into first and second fluid streams. The second fluid stream has a higher density than the first fluid stream. The mixing chamber includes a first inlet, a second inlet and a mixing well. The second inlet is positioned below the first inlet. The second inlet of the mixing chamber is configured to receive the first fluid stream and the first inlet of the mixing chamber is configured to receive the second fluid stream to promote mixing of the first and second streams in the mixing well.

5. 发明申请

WO2017218134A1 MINIATURE DEVICE HAVING AN ACOUSTIC DIAPHRAGM 审中-公开
标题翻译：具有声学隔膜的微型器件
公开(公告)号：WO2017218134A1
公开(公告)日：2017-12-21
申请号：PCT/US2017/033283
申请日：2017-05-18
申请人： BOSE CORPORATION
发明人： BUSHKO, Wit , LANDEMAINE, Thomas , NATH, Prateek
IPC分类号： H04R7/10 , H04R31/00 , H04R7/16
摘要： A method of forming a device having a compliant member (16) includes creating a membrane (22) having one or more elastomeric layers which are at least partially cured. Another elastomeric layer (26) is provided on the membrane (22) in an uncured state. A bobbin (30) and a housing (28) are positioned so that an end of the bobbin or housing, or the ends of both the bobbin and housing, extend at least partially into the uncured elastomeric layer (26). The uncured elastomeric layer (26) is then cured to secure it to the membrane (22) and to the housing (18) or bobbin (30), or both the housing and bobbin. The method substantially reduces or eliminates the formation of holes that can form during fabrication or use of the device.
摘要翻译：一种形成具有柔性构件（16）的装置的方法包括形成具有一个或多个至少部分固化的弹性体层的膜（22）。另一弹性体层（26）以未固化状态设置在膜（22）上。线轴（30）和壳体（28）被定位成使得线轴或壳体的端部或线轴和壳体的端部至少部分地延伸到未固化的弹性体层（26）中。然后固化未固化的弹性体层（26）以将其固定到膜（22）和壳体（18）或线轴（30）上，或固定到壳体和线轴上。该方法大大减少或消除了在制造或使用该装置期间可形成的孔的形成。

6. 发明申请

WO2017139095A1 ELECTRICAL CIRCUIT BOARD WITH EMBEDDED ACOUSTIC CHANNEL 审中-公开
标题翻译：带有嵌入式声道的电路板
公开(公告)号：WO2017139095A1
公开(公告)日：2017-08-17
申请号：PCT/US2017/014886
申请日：2017-01-25
申请人： BOSE CORPORATION
发明人： O'CONNELL, Michael
IPC分类号： H05K1/02 , H04R1/00
CPC分类号： H04R1/1016 , H04R1/1008 , H04R1/1091 , H04R5/033 , H05K1/0272 , H05K1/028 , H05K1/0298 , H05K2201/09009 , H05K2201/09072 , H05K2201/10083
摘要： An electrical circuit board assembly (60) that can be used in a headphone includes acoustic elements incorporated into a rigid or flexible circuit board (62). The electrical circuit board assembly permits the convenient routing of electrical circuitry (68) and acoustic elements, such as an acoustic port (70), between acoustic chambers in the headphone. The acoustic port includes a channel embedded in the circuit board. Control of the dimensions of the channel is achieved using conventional circuit board assembly techniques. Advantageously, the circuit board assembly enables convenient and repeatable assembly into headphones, such as earbuds, and results in more consistent acoustic performance from the headphones.
摘要翻译：可用于头戴式耳机的电路板组件（60）包括结合到刚性或柔性电路板（62）中的声学元件。电路板组件允许电路（68）和诸如声学端口（70）的声学元件在头戴式耳机中的声学室之间方便地布线。声学端口包括嵌入在电路板中的通道。使用传统的电路板组装技术来实现对通道尺寸的控制。有利的是，电路板组件能够方便且可重复地组装成耳机，例如耳机，并且导致耳机的更一致的声学性能。

7. 发明申请

WO2013148071A1 SAMPLE CARRIER FOR DRIED BIOLOGICAL SAMPLES 审中-公开
标题翻译：用于干燥生物样品的样品载体
公开(公告)号：WO2013148071A1
公开(公告)日：2013-10-03
申请号：PCT/US2013/028808
申请日：2013-03-04
申请人： WATERS TECHNOLOGIES CORPORATION
发明人： ZHANG, Xin , IRANETA, Pamela C. , JUNG, Moon Chul , LONGENBACH, Pamela , MARSZALKOWSKI, Frank
IPC分类号： C12M1/00
CPC分类号： G01N1/30 , B01L3/5088 , B01L2300/126 , B01L2300/161 , G01N1/10 , G01N33/5436 , G01N33/96 , G01N2291/02466
摘要： Described is a biological sample carrier based on a rigid hydrophilic object fabricated from a non-absorbing inert porous material. A biological fluid sample applied to the surface of the object is absorbed into the pores and constituents of the biological fluid sample remain in the pores after drying. Unlike a disc punched from a conventional dried blood spot (DBS) card, the object is easily handled. In contrast to DBS cards containing glass fiber structures that interact with basic analytes and other DBS card having adsorbing fibers that tend to separate blood constituents as the sample spreads through the fibers, the biological sample carrier is substantially inert to drug analytes.
摘要翻译：描述了基于由非吸收惰性多孔材料制造的刚性亲水物体的生物样品载体。施加到物体表面的生物流体样品被吸收到孔中，并且干燥后生物流体样品的成分保留在孔中。与传统的干血斑（DBS）卡片冲孔不同，该物体易于处理。与含有与碱性分析物相互作用的玻璃纤维结构的DBS卡和具有吸附纤维的其它DBS卡相反，当样品扩散通过纤维时，其具有倾向于分离血液成分的生物样品载体对药物分析物基本上是惰性的。

8. 发明申请

WO2013032835A1 REUSABLE FITTING FOR ATTACHING A CONDUIT TO A PORT 审中-公开
标题翻译：连接到港口的可重复配件
公开(公告)号：WO2013032835A1
公开(公告)日：2013-03-07
申请号：PCT/US2012/051981
申请日：2012-08-23
申请人： WATERS TECHNOLOGIES CORPORATION , MICHIENZI, Joseph D.
发明人： MICHIENZI, Joseph D.
IPC分类号： F16L19/02
CPC分类号： B05B5/16 , B01D15/10 , B01D15/1871 , B01D15/22 , G01N30/60 , G01N30/6004 , G01N30/6026 , G01N30/603 , G01N30/6039 , G01N30/6052 , G01N30/6095 , G01N30/7266 , Y10T29/49908
摘要： Described is a reusable fitting for attaching a conduit to a port. The fitting includes a housing, a spring, a retainer and a cap. The retainer is capable of locking and unlocking a conduit in the fitting. The fitting provides a high pressure fluid-tight seal and a substantially zero void volume at the junction of two fluidic conduits. The fitting is removable, reusable and replaceable, and allows a user to make and remake connections of a capillary to a fluidic port without permanently binding a ferrule to a specific capillary and thus to a specific port. The fitting can be replaced if part or all of the fitting is damaged during use.
摘要翻译：描述的是用于将导管附接到端口的可重复使用的配件。配件包括壳体，弹簧，保持器和盖。保持器能够锁定和解锁配件中的导管。该配件在两个流体管道的连接处提供高压流体密封和基本为零的空隙体积。该配件是可拆卸的，可重复使用的并且可更换的，并且允许使用者将毛细管连接到流体端口，而不必将套圈永久地固定到特定的毛细管并因此连接到特定的端口。如果零件或全部配件在使用过程中损坏，可以更换配件。

9. 发明申请

WO2013032833A1 LIQUID CHROMATOGRAPHY CONDUIT ASSEMBLIES HAVING HIGH PRESSURE SEALS 审中-公开
标题翻译：具有高压密封的液相色谱仪组件
公开(公告)号：WO2013032833A1
公开(公告)日：2013-03-07
申请号：PCT/US2012/051974
申请日：2012-08-23
申请人： WATERS TECHNOLOGIES CORPORATION , MICHIENZI, Joseph D.
发明人： MICHIENZI, Joseph D.
IPC分类号： B01D15/08
CPC分类号： B05B5/16 , B01D15/10 , B01D15/1871 , B01D15/22 , G01N30/60 , G01N30/6004 , G01N30/6026 , G01N30/603 , G01N30/6039 , G01N30/6052 , G01N30/6095 , G01N30/7266 , Y10T29/49908
摘要： Described is a tubing assembly which includes a permanently deformable outer tube, an intermediate tube and an inner tube. A radial seal is provided by a uniform radial crimp having a non-zero longitudinal length at a longitudinal location on the tubing assembly. In some embodiments one or both ends of the assembly have a uniform radial crimp and are polished so that the ends of two or more of the tubes are substantially flush with each other to thereby block the passage of fluids between the ends of the tubes. In other embodiments the uniform radial crimps are at other longitudinal locations where a high pressure seal is desired. The longitudinal length and the depth of each uniform radial crimp can be formed to accommodate the requirements of a particular application so that leakage along the tubing assembly is prevented and void volume is reduced or eliminated.
摘要翻译：描述了一种管组件，其包括永久变形的外管，中间管和内管。通过在管组件上的纵向位置处具有非零纵向长度的均匀径向压接件来提供径向密封。在一些实施例中，组件的一端或两端具有均匀的径向压接并且被抛光，使得两个或更多个管的端部彼此基本齐平，从而阻止流体在管的端部之间的通过。在其它实施例中，均匀的径向卷曲位于需要高压密封的其它纵向位置处。可以形成每个均匀径向卷曲的纵向长度和深度以适应特定应用的要求，从而防止沿着管道组件的泄漏并减少或消除空隙体积。

10. 发明申请

WO2012003018A1 METHOD FOR LOW SIDELOBE OPERATION OF A PHASED ARRAY ANTENNA HAVING FAILED ANTENNA ELEMENTS 审中-公开
标题翻译：具有失效天线元素的相位阵列天线的低边界操作方法
公开(公告)号：WO2012003018A1
公开(公告)日：2012-01-05
申请号：PCT/US2011/029734
申请日：2011-03-24
申请人： MASSACHUSETTS INSTITUTE OF TECHNOLOGY , KRICH, Steven Ira , PRUST, Cory J. , WEINER, Ian
发明人： KRICH, Steven Ira , PRUST, Cory J. , WEINER, Ian
IPC分类号： H01Q3/26
CPC分类号： H01Q3/26
摘要： Described is a method of modifying an antenna pattern for a phased array antenna having at least one failed antenna element. A number of proximate beamformers in a proximate angular region about a beamformer at an angle of interest are determined. Each of the proximate beamformers has a proximate beamformer weight vector. A corrected beamformer weight vector is determined for the angle of interest as a linear combination of the proximate beamformer weight vectors. Each element of the corrected beamformer weight vector that corresponds to one of the failed antenna elements has a value of zero. The method enables computation of low spatial sidelobe antenna patterns without requiring a recalibration of the antenna thereby enabling uninterrupted operation of systems that employ phased array antennas. The method can also be used to control taper loss or sidelobe level for phased array antennas that have no failed antenna elements.
摘要翻译：描述了一种用于修改具有至少一个故障天线元件的相控阵天线的天线方向图的方法。确定在感兴趣的角度处关于波束形成器的邻近角度区域中的多个邻近波束形成器。每个近邻波束形成器具有邻近波束形成器权重向量。对于感兴趣的角度来确定校正的波束形成器权重向量作为邻近波束形成器权重向量的线性组合。对应于一个故障天线元件的校正波束形成器权重向量的每个元素具有零值。该方法能够计算低空间旁瓣天线图案，而不需要对天线进行重新校准，从而实现采用相控阵天线的系统的不间断操作。该方法还可用于控制没有故障天线元件的相控阵天线的锥度损耗或旁瓣电平。

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