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1. 发明申请

WO2015027144A1 IMPLANTABLE MEDICAL DEVICES 审中-公开
标题翻译：可植入医疗器械
公开(公告)号：WO2015027144A1
公开(公告)日：2015-02-26
申请号：PCT/US2014/052264
申请日：2014-08-22
申请人： ALLERGAN, INC.
发明人： SERBAN, Monica A. , BURKE, Susan E. , DAUNCH, William A. , PATEL, Vinit , JONES, Bryan W. , LIMEM, Skander , AKERS, Jessica L. , PATEL, Kantilal N.
IPC分类号： B32B5/02
CPC分类号： A61L31/047 , A61F2/0063 , A61L31/005 , B32B5/024 , B32B5/026 , B32B5/028 , B32B2262/08 , B32B2556/00 , D04B21/16 , D10B2211/04 , D10B2403/0213 , D10B2509/08
摘要： Laminate or knitted medical devices and methods using such devices to support soft tissues and/or to reduce formation of post-operative adhesions. The medical devices can comprise a layer of a knitted silk mesh to which has been fused a water soluble or insoluble silk film or silk sponge, and/or a layer of a knitted silk mesh which was co-knitted with one, two or three layers of silk or non-silk fabric.
摘要翻译：使用这种装置的层压或针织医疗装置和方法来支持软组织和/或减少术后粘连的形成。医疗装置可以包括已经融合了水溶性或不溶性丝膜或丝绸海绵的针织丝网层和/或与一层，两层或三层共同编织的针织丝网层丝绸或非丝织物。

2. 发明申请

WO2014093837A1 SILK MEDICAL DEVICE 审中-公开
标题翻译：丝绸医疗器械
公开(公告)号：WO2014093837A1
公开(公告)日：2014-06-19
申请号：PCT/US2013/075041
申请日：2013-12-13
申请人： ALLERGAN, INC.
发明人： MORTARINO, Enrico
IPC分类号： D04B21/12 , A61F2/00
CPC分类号： D04B21/12 , A61F2/0063 , A61F2210/0004 , A61L31/005 , A61L31/148 , D10B2211/04 , D10B2509/08
摘要： An implantable knitted silk mesh for use in human soft tissue support and repair having a particular knit pattern that substantially prevents unraveling and preserves the stability of the mesh when cut, the knitted mesh including at least two yarns laid in a knit direction and engaging each other to define a plurality of nodes.
摘要翻译：一种用于人类软组织支撑和修复的可植入针织丝网，其具有特定的针织图案，其基本上防止在切割时解开并保持网状物的稳定性，针织网包括至少两根以编织方向布置并相互接合的纱线以定义多个节点。

3. 发明申请

WO2014022657A1 MUCOSAL TISSUE ADHESION VIA TEXTURED SURFACE 审中-公开
标题翻译：通过纹理表面的粘膜组织粘合
公开(公告)号：WO2014022657A1
公开(公告)日：2014-02-06
申请号：PCT/US2013/053213
申请日：2013-08-01
申请人： ALLERGAN, INC.
发明人： SCHWAB, Justin J. , RAVEN, Joseph S. , LIU, Futian
IPC分类号： A61L27/16 , A61L27/18 , A61L27/56
CPC分类号： A61L27/16 , A61L27/18 , A61L27/56 , A61L31/10 , A61L31/146 , A61L2400/08 , A61L2430/22 , C08L53/02 , C08L83/04 , C08L23/22
摘要： The present specification discloses porous materials, methods of forming such porous material, biocompatible implantable devices comprising such porous materials, and methods of making such biocompatible implantable devices. The porous material may be used to fix to the interior mucosal lining of a patient's gastrointestinal tract.
摘要翻译：本说明书公开了多孔材料，形成这种多孔材料的方法，包括这种多孔材料的生物相容性可植入装置以及制造这种生物相容性可植入装置的方法。多孔材料可以用于固定到患者胃肠道的内部粘膜衬里。

4. 发明申请

WO2013123272A1 COMPOSITIONS AND IMPROVED SOFT TISSUE REPLACEMENT METHODS 审中-公开
标题翻译：组合物和改进的软组织替代方法
公开(公告)号：WO2013123272A1
公开(公告)日：2013-08-22
申请号：PCT/US2013/026248
申请日：2013-02-15
申请人： ALLERGAN, INC.
发明人： VAN EPPS, Dennis E. , JIANG, Guang-Liang , COLLETTE, Adam L. , HORAN, Rebecca L. , CHEN, Jing Song , ALTMAN, Gregory H. , IM, Wha-Bin
IPC分类号： A61K45/06 , A61K9/14 , A61K31/381 , A61K31/4015 , A61K31/4025 , A61K31/45 , A61K31/41 , A61P17/02
CPC分类号： A61K31/5575 , A61K31/381 , A61K31/4015 , A61K31/4025 , A61K31/41 , A61K31/4245 , A61K31/45 , A61K31/5585 , A61K31/559 , A61K45/06 , A61L27/3604 , A61L27/54 , A61L27/58 , A61L2430/34
摘要： The specification discloses compositions and methods for treating a soft tissue defect of an individual.
摘要翻译：该说明书公开了用于治疗个体的软组织缺陷的组合物和方法。

5. 发明申请

WO2013123270A1 COMPOSITIONS AND IMPROVED SOFT TISSUE REPLACEMENT METHODS 审中-公开
标题翻译：组合物和改进的软组织替代方法
公开(公告)号：WO2013123270A1
公开(公告)日：2013-08-22
申请号：PCT/US2013/026246
申请日：2013-02-15
申请人： ALLERGAN, INC.
发明人： VAN EPPS, Dennis E. , JIANG, Guang-Liang , COLLETTE, Adam L. , HORAN, Rebecca L. , CHEN, Jing Song , ALTMAN, Gregory H. , IM, Wha-Bin
IPC分类号： A61K31/381 , A61K31/4015 , A61K31/4025 , A61K31/45 , A61K45/06 , A61K9/14 , A61P17/02
CPC分类号： A61K31/4245 , A61K31/381 , A61K31/4015 , A61K31/4025 , A61K31/45 , A61K45/06
摘要： The specification discloses compositions and methods for treating a soft tissue defect of an individual.
摘要翻译：本说明书公开了用于治疗个体的软组织缺陷的组合物和方法。

6. 发明申请

WO2013096392A1 SELF-SEALING FLUID JOINT FOR USE WITH A GASTRIC BAND 审中-公开
标题翻译：自密封流体接头与带子带一起使用
公开(公告)号：WO2013096392A1
公开(公告)日：2013-06-27
申请号：PCT/US2012/070517
申请日：2012-12-19
申请人： ALLERGAN, INC.
发明人： HONARYAR, Babak , SNOW, Sean
IPC分类号： A61F5/00 , A61M39/02 , A61M39/10 , F16L31/00 , F16L37/06
CPC分类号： A61M39/0208 , A61F5/003 , A61F5/0056 , A61M39/0247 , A61M2039/0255 , A61M2039/0276 , A61M2039/1027
摘要： Generally described herein are apparatus, systems and methods related to a mechanical interlock joint geometry for various components and joining of components thereby creating a reliable seal against fluid leaks that is resistant at typical pressures experienced when the components are implanted into a human body. Furthermore, the seal may be enhanced when a fluid pressure exerted inside the components is increased (e.g., from 1 to 10 psi).
摘要翻译：这里通常描述的是与用于各种部件的机械联锁接头几何形状和部件接合相关的装置，系统和方法，从而产生可靠的密封，以防止当将部件植入人体时经受的典型压力下的流体泄漏。此外，当施加在部件内部的流体压力增加（例如，从1至10psi）时，可以增强密封。

7. 发明申请

WO2013074343A1 PRE-LOADED SEPTUM FOR USE WITH AN ACCESS PORT 审中-公开
标题翻译：预先加载的SEPTUM用于使用入口
公开(公告)号：WO2013074343A1
公开(公告)日：2013-05-23
申请号：PCT/US2012/063834
申请日：2012-11-07
申请人： ALLERGAN, INC.
发明人： HONARYAR, Babak
IPC分类号： A61F5/00 , A61M39/02 , A61M39/00
CPC分类号： A61F5/0056 , A61M39/0208 , A61M39/0247 , A61M39/04 , A61M2039/0036 , A61M2039/0072 , A61M2039/0223 , A61M2039/0229 , A61M2039/0235 , A61M2039/0255 , A61M2039/027 , A61M2039/0276 , A61M2039/0282
摘要： Generally described herein are apparatus, systems and methods related to a pre-loaded septum insertable in an access port housing for increasing the control of the compression within the septum and the interference between the septum and the housing. For example, a pair of washers having mating portions may be positioned on respective sides of a rubber septum and bent such that the mating portions of one of the washer are interlocked with the mating portions of the other washer, the interlocked portions forming a tight ring about the septum and generating lateral compression on the septum, thereby "loading" the septum. In addition, fluid seals made of a rubber material with lower durometer than the rubber septum may be used at the interface between the rubber septum and the housing to enhance the fluid sealing functionality while promoting the self-sealing features of the rubber septum.
摘要翻译：本文通常描述的是与可插入进入口壳体中的预加载隔垫相关的装置，系统和方法，用于增加对隔膜内的压缩的控制以及隔膜和外壳之间的干涉。例如，具有配合部分的一对垫圈可以位于橡胶隔膜的相应侧上并弯曲成使得其中一个垫圈的配合部分与另一个垫圈的配合部分互锁，互锁部分形成一紧固环关于隔膜并在隔膜上产生横向压缩，从而“加载”隔膜。此外，橡胶隔片和外壳之间的界面可以使用橡胶材料制成的比橡胶隔膜低的橡胶材料的流体密封件，以增强流体密封功能，同时促进橡胶隔膜的自密封特征。

8. 发明申请

WO2012148735A1 A PROSTHETIC DEVICE HAVING DIAGONAL YARNS AND METHOD OF MANUFACTURING THE SAME 审中-公开
标题翻译：具有对角纱的前置装置及其制造方法
公开(公告)号：WO2012148735A1
公开(公告)日：2012-11-01
申请号：PCT/US2012/033943
申请日：2012-04-17
申请人： ALLERGAN, INC. , MORTARINO, Enrico
发明人： MORTARINO, Enrico
IPC分类号： A61F2/00 , D04B1/08 , D04B21/12 , D04B21/00
CPC分类号： A61F2/0063 , A61F2/12 , A61F2002/0068 , A61L27/3604 , D04B1/22 , D04B21/08 , D04B21/12 , D10B2509/08
摘要： A knitted scaffold comprising at least two silk yarns in a knit direction and a yarn member diagonal to the knit direction to thereby provide a knitted fabric or mesh for surgical use that can retain its shape and/or resist collapse when opposing forces are applied at an angle from the knit direction. The knitted scaffold may include at least two yarns laid in a knit direction and engaging each other to define a plurality of nodes. The at least two yarns can include a first yarn and a second yarn extending between and forming loops about two nodes. The second yarn has a higher tension at the two nodes than the first yarn. The second yarn substantially prevents the first yarn from moving at the two nodes and substantially prevents the knitted mesh from unraveling at the nodes.
摘要翻译：一种编织支架，其包括至少两根编织方向的丝线和与编织方向对角的纱线构件，从而提供用于外科用途的针织物或网状物，其可以在相对的力施加在角度从编织方向。针织支架可以包括至少两根以编织方向铺设的纱线并且彼此接合以限定多个节点。所述至少两根纱线可以包括第一纱线和在两个节点之间延伸并形成环的第二纱线。第二根纱线在两个节点处的张力比第一根纱线高。第二纱线基本上防止第一纱线在两个节点处移动，并且基本上防止针织网在节点处解开。

9. 发明申请

WO2012142214A1 SYRINGE-BASED LEAK DETECTION SYSTEM 审中-公开
标题翻译：基于SYRINGE的泄漏检测系统
公开(公告)号：WO2012142214A1
公开(公告)日：2012-10-18
申请号：PCT/US2012/033210
申请日：2012-04-12
申请人： ALLERGAN, INC. , SNOW, Sean , O'DONNELL, Mark , TEZEL, Amy , BORRELL, Marcos
发明人： SNOW, Sean , O'DONNELL, Mark , TEZEL, Amy , BORRELL, Marcos
IPC分类号： A61F5/00
CPC分类号： A61F5/0056 , A61F2005/002 , G01M3/04 , G01M3/26
摘要： Generally described herein are devices, methods and systems related to detecting a leak present in a gastric banding system for the treatment of obesity. For example, a leak detector may include a syringe, a leak sensing unit and a needle, and may measure a pressure decay within a gastric banding system after the needle penetrates the patient's skin and is inserted into an access port connected to the gastric band of the gastric banding system. The pressure decay may be interpreted to determine if a leak is present in the gastric banding system.
摘要翻译：本文通常描述的是与检测用于治疗肥胖症的胃束带系统中存在的泄漏相关的装置，方法和系统。例如，泄漏检测器可以包括注射器，泄漏检测单元和针，并且可以在针穿透患者皮肤之后测量胃束带系统内的压力衰减，并且插入与胃带的连接的入口胃束带系统。可以解释压力衰减以确定胃束带系统中是否存在泄漏。

10. 发明申请

WO2012054414A2 STOMACH-SPANNING GASTRIC IMPLANTS 审中-公开
标题翻译：胃切口胃癌植入物
公开(公告)号：WO2012054414A2
公开(公告)日：2012-04-26
申请号：PCT/US2011/056614
申请日：2011-10-18
申请人： ALLERGAN, INC. , BABKES, Mitchell, H. , DOMINGUEZ, Zachary, P.
发明人： BABKES, Mitchell, H. , DOMINGUEZ, Zachary, P.
IPC分类号： A61F5/00
CPC分类号： A61F5/0079 , A61F5/0033 , A61F5/0036
摘要： A variety of passive intragastric implant devices for obesity treatment are disclosed. Such passive implants do not autonomously change shape, but instead react within the stomach to induce satiety. The implants may take up volume within the stomach, thus reducing the digestive capacity. Additionally, the implants may contact areas within the stomach, such as the cardia surrounding the esophageal sphincter, to stimulate satiety-inducing nerves. Also, a number of implants slow gastric emptying by blocking or otherwise impeding flow through the pyloric sphincter. Other implants delay digestion by providing a duodenal sleeve. A number of implants combine two or more of these satiety-inducing features. Methods of implant are disclosed including compressing the implants within a delivery tube and transorally advancing the implants through the esophagus to be deployed within the stomach. Removal of the implants occurs in the reverse.
摘要翻译：公开了用于肥胖治疗的各种被动胃内植入装置。这种被动植入物不会自主地改变形状，而是在胃内反应以引起饱腹感。植入物可能会占用胃内的体积，从而降低消化能力。另外，植入物可以接触胃内的区域，例如围绕食道括约肌的贲门，以刺激引起饱腹感的神经。而且，许多植入物通过阻断或阻碍通过幽门括约肌的流动来减缓胃排空。其他植入物通过提供十二指肠套管延迟消化。许多植入物将两种或更多种这些引起饱腹感的特征结合起来。公开了植入方法，包括压缩输送管内的植入物并经口腔推进植入物通过食道以部署在胃内。反向移除植入物。

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