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1. 发明申请

WO2018104805A1 SMART NEBULIZER 审中-公开
公开(公告)号：WO2018104805A1
公开(公告)日：2018-06-14
申请号：PCT/IB2017/055603
申请日：2017-09-15
申请人： TRUDELL MEDICAL INTERNATIONAL
发明人： COSTELLA, Stephen , DITTMER, Andrew , KILROY, Luke , KIRCHNER, Alanna , MORTON, Robert , SCHMIDT, James
IPC分类号： A61M11/00 , A61K9/72 , A61M15/00 , A61M99/00
摘要： A nebulizer system capable of identifying when activation has occurred and aerosol is being produced. The nebulizer system monitors the inhalation and exhalation flow generated by the patient and communicates proper breathing technique for optimal drug delivery. The nebulizer system may monitor air supply to the nebulizer to ensure it is within the working range and is producing, or is capable of producing, acceptable particle size and drug output rate. When a patient, caregiver or other user deposits or inserts medication into the nebulizer, the nebulizer system is able to identify the medication and determine the appropriate delivery methods required to properly administer the medication as well as output this information into a treatment log to ensure the patient is taking the proper medications. The system is able to measure the concentration of the medication and volume of the medication placed within the medication receptacle, e.g., bowl.

2. 发明申请

WO2017017657A1 COMBINED RESPIRATORY MUSCLE TRAINING AND OSCILLATING POSITIVE EXPIRATORY PRESSURE DEVICE 审中-公开
标题翻译：组合呼吸肌肉训练和振动正压通气装置
公开(公告)号：WO2017017657A1
公开(公告)日：2017-02-02
申请号：PCT/IB2016/054577
申请日：2016-07-29
申请人： TRUDELL MEDICAL INTERNATIONAL
发明人： MEYER, Adam , ENGELBRETH, Dan
IPC分类号： A61M16/00 , A61H99/00 , A61M16/20
CPC分类号： A61M16/208 , A61M11/00 , A61M15/00 , A61M16/0006 , A61M16/06 , A61M16/0866 , A61M16/20 , A63B21/00069 , A63B21/023 , A63B23/18 , A63B2071/0694
摘要： A respiratory treatment device for the combined administration of respiratory muscle training ("RMT") and oscillating positive expiratory pressure ("OPEP") therapy, and administration of RMT using pressure threshold resistors and flow resistors with respiratory treatment devices, such as OPEP devices.
摘要翻译：呼吸治疗装置，用于呼吸肌训练（“RMT”）和振荡正呼气压（“OPEP”）治疗的联合施用，以及使用压力阈值电阻器和具有呼吸治疗装置（例如OPEP装置）的流阻器施用RMT。

3. 发明申请

WO2016113683A1 RESPIRATORY INTERFACE 审中-公开
标题翻译：呼吸界面
公开(公告)号：WO2016113683A1
公开(公告)日：2016-07-21
申请号：PCT/IB2016/050143
申请日：2016-01-13
申请人： TRUDELL MEDICAL INTERNATIONAL
发明人： GULKA, Noel , BARAN, George
IPC分类号： A61M11/02 , A61K9/72 , A61M11/06 , A61M16/06
CPC分类号： A61M16/0488 , A61M11/02 , A61M11/06 , A61M15/0021 , A61M15/0086 , A61M15/009 , A61M16/049 , A61M16/0493 , A61M16/0495 , A61M16/0816 , A61M16/209 , A61M2240/00
摘要： A patient respiratory interface for use in an aerosol delivery system is disclosed. The interface may provide a mechanism for introducing an aerosolized medicament to infants without the need for invasive intubation when treating issues in infants such as infant respiratory distress syndrome. The interface may include an outer body formed in the shape of a pacifier where the insertion portion of the pacifier may be hollow and have an opening to guide a catheter or other tubing that may be passed through a flange and the insertion portion of the interface. The catheter may be recessed from or extend slightly out of the tip of the insertion portion so that a flow of nebulized medicament may be delivered to the patient's oropharynx in aerosol form.
摘要翻译：公开了一种用于气雾剂输送系统的患者呼吸界面。界面可以提供一种机制，用于在治疗诸如婴儿呼吸窘迫综合征的婴儿中的问题时将气雾化药物引入婴儿而不需要侵入性插管。界面可以包括形成为奶嘴形状的外部主体，其中奶嘴的插入部分可以是中空的并且具有用于引导可以穿过凸缘的导管或其它管道的开口以及界面的插入部分。导管可以从插入部分的尖端凹陷或稍微延伸，使得雾化药物的流动可以以气溶胶形式递送到患者的口咽部。

4. 发明申请

WO2014140765A1 VENTILATOR CIRCUIT, ADAPTER FOR USE IN VENTILATOR CIRCUIT AND METHODS FOR THE USE THEREOF 审中-公开
标题翻译：通风机电路，适用于通风机电路的适配器及其使用方法
公开(公告)号：WO2014140765A1
公开(公告)日：2014-09-18
申请号：PCT/IB2014/000349
申请日：2014-03-14
申请人： TRUDELL MEDICAL INTERNATIONAL
发明人： ALIZOTI, Neritan , SCHMIDT, James
IPC分类号： A61M16/20 , A61M15/00 , A61M16/08 , A61M16/10
CPC分类号： A61M16/14 , A61M11/00 , A61M11/005 , A61M11/007 , A61M11/06 , A61M15/00 , A61M15/0025 , A61M15/0065 , A61M15/0085 , A61M15/009 , A61M16/0463 , A61M16/0816 , A61M16/0833 , A61M16/20 , A61M16/208 , A61M2202/0208 , A61M2205/02
摘要： An adapter includes a housing having an inlet port defining a flow path and an outlet port. An interior wall has an inner surface defining an interior passageway communicating with the outlet port and an exterior surface defining an exterior passageway communicating with the inlet port. The interior wall defines a mouth communicating between the interior and the exterior passageways. The interior wall is positioned transverse to the flow path of the inlet port. A medicament delivery port opens into the mouth. A valve is moveable between a closed position, wherein the valve closes the medicament delivery port, and an open position, wherein the medicament delivery port is open. A ventilator circuit and method of delivering a medicament are also provided.
摘要翻译：适配器包括具有限定流路的入口端口和出口的壳体。内壁具有限定与出口连通的内部通道的内表面和限定与入口连通的外部通道的外表面。内壁限定了在内部和外部通道之间连通的口。内壁横向于入口的流动路径定位。药物输送口通向口中。阀可在闭合位置之间移动，在关闭位置，其中阀关闭药物输送口，以及打开位置，其中药物输送口打开。还提供了一种呼吸机回路和递送药物的方法。

5. 发明申请

WO2013046013A1 NASAL INSERT AND CANNULA AND METHODS FOR THE USE THEREOF 审中-公开
标题翻译： NASAL INSERT和CANNULA及其使用方法
公开(公告)号：WO2013046013A1
公开(公告)日：2013-04-04
申请号：PCT/IB2012/001929
申请日：2012-09-28
申请人： TRUDELL MEDICAL INTERNATIONAL
发明人： FOLEY, Martin, P. , GRYCHOWSKI, Jerry
IPC分类号： A61F5/56 , A61M16/20
CPC分类号： A61F5/56 , A61F5/08
摘要： A nasal insert includes a housing having a circumferential wall defining an interior passage. The wall has a longitudinal gap extending along a length thereof, with an outer peripheral dimension of the housing being adjustable by varying the gap. A valve is in communication with the interior passage and limits a fluid flow through the interior passage in at least one direction. In another embodiment, a nasal insert includes a user interface having a tubular housing defining an interior cavity open at opposite ends. An exterior surface of the housing is adapted to interface with a nasal vestibule of a user. A base is received in the interior cavity of the housing and includes an exit port. A cap is connected to the base and has an input port. A valve member is disposed in an interior passage defined by at least one of the cap and base, with the valve member being moveably received in the interior passage. Methods of using and assembling the nasal inserts also are provided.
摘要翻译：鼻插入物包括具有限定内部通道的周向壁的壳体。壁具有沿其长度延伸的纵向间隙，壳体的外周尺寸可通过改变间隙来调节。阀与内部通道连通并限制在至少一个方向上通过内部通道的流体流动。在另一个实施例中，鼻插入物包括具有管状壳体的用户界面，所述管状壳体限定在相对端部处敞开的内部空腔。外壳的外表面适于与使用者的鼻前庭接触。基座被容纳在壳体的内腔中并且包括出口。盖子连接到基座并具有输入端口。阀构件设置在由帽和底座中的至少一个限定的内部通道中，阀构件可移动地容纳在内部通道中。还提供了使用和组装鼻插入物的方法。

6. 发明申请

WO2013027078A8 AEROSOL DELIVERY DEVICE 审中-公开
公开(公告)号：WO2013027078A8
公开(公告)日：2013-02-28
申请号：PCT/IB2011/001936
申请日：2011-08-24
申请人： TRUDELL MEDICAL INTERNATIONAL
发明人： FINLAY, Bryan , NUTTALL, Michael , COULTES, Brandon , NAGEL, Mark , PICKARD, Mark
IPC分类号： A61M11/02 , B05B7/24
摘要： An aerosol delivery system is disclosed that is a single-use (disposable) continuous nebulizer system designed for use with mechanically ventilated patients to aerosolize medications for inhalation with a general purpose nebulizer, or for connection with devices usable in endoscopic procedures. The system separates the liquid reservoir from the nebulization process taking place either at the adapter hub, where it fits into an endotracheal tube (ETT), or a gas humidifier, where the aerosol may treat a gas used in an endoscopic procedure, with a multi-lumen tube configured to nebulize liquid and air at its distal end. The refillable liquid reservoir is mounted away from the immediate treatment zone, avoiding orientation issues associated with other types of nebulizers having a self-contained reservoir. The system can produce aerosols having a wide range of droplet sizes, depending upon central lumen diameter, with values of MMAD that range from 4 to 30 pm.

7. 发明申请

WO2009071986A2 SYSTEMS AND METHODS FOR EVALUATING MEDICATION DELIVERY FROM VALVED HOLDING CHAMBERS WITH A FACEMASK USING A MODEL FACE 审中-公开
标题翻译：使用模型表面评估使用FACEMASK的阀门进行药物输送评估的系统和方法
公开(公告)号：WO2009071986A2
公开(公告)日：2009-06-11
申请号：PCT/IB2008/003371
申请日：2008-12-05
申请人： TRUDELL MEDICAL INTERNATIONAL
发明人： LIMBRICK, Myles , MORTON, Robert , NAGEL, Mark , MITCHELL, Jolyon , GUBBELS, Peter , WIERSEMA, Kimberly , DOYLE, Cathy , AVVAKOUMOVA, Valentina
IPC分类号： G01M99/00
CPC分类号： A61M16/06 , A61M15/009 , A61M2016/0027 , A61M2016/003 , A61M2209/02 , A61M2209/084 , A61M2210/0606 , A62B27/00 , G09B23/32
摘要： Systems and methods for evaluating medication delivery from valved holding chambers (VHCs) with a facemask using a model face of a child or a model face of an infant are disclosed. Generally, the model face includes "a base, an elastomer cast, an air pocket, and a mouth opening. The elastomer cast is positioned on at least a portion of a top of the base. The elastomer simulates soft tissues in a face and defiens at least a nose, a chin, and a mouth sized to simulate a nose, a chin, and a mouth of a child. The air pocket is positioned between the base and the elastomer case below at least the nose, the chin, and the mouth of the elastomer cast. The mouth opening defines a passageway through the base, the air pocket, and the mouth of the elastomer cast.
摘要翻译：公开了使用儿童的模型面或婴儿的模型面评估带有面罩的带阀门的室内（VHC）的药物递送的系统和方法。通常，模型面包括“基底，弹性体铸件，气穴和开口”，弹性体铸件位于基体顶部的至少一部分上，弹性体模拟面部的软组织至少一个鼻子，一个下巴和一个口大小模拟鼻子，一个下巴和一个孩子的嘴巴，气囊位于底部和弹性体外壳之间，至少在鼻子，下巴和嘴部开口限定通过基座，气穴和弹性体口的通道。

8. 发明申请

WO2008024375A2 RESPIRATORY MUSCLE ENDURANCE TRAINING DEVICE AND METHOD FOR THE USE THEREOF 审中-公开
标题翻译：呼吸肌训练装置及其使用方法
公开(公告)号：WO2008024375A2
公开(公告)日：2008-02-28
申请号：PCT/US2007/018527
申请日：2007-08-21
申请人： TRUDELL MEDICAL INTERNATIONAL , FOLEY, Martin , GRYCHOWSKI, Jerry, R.
发明人： FOLEY, Martin , GRYCHOWSKI, Jerry, R.
IPC分类号： A63B23/18
CPC分类号： A63B23/18 , A61B5/01 , A61B5/0836 , A61B5/097 , A61B5/486 , A63B2230/433
摘要： A respiratory muscle endurance training device (RMET) includes a chamber and a patient interface. In one implementation, one or both of a CO 2 sensor or a temperature sensor can be coupled to the chamber or patient interface to provide the user or caregiver with indicia about the CO 2 level in, or the temperature of, the chamber or patient interface, and/or the duration of use of the device. In another implementation, the RMET may have a fixed volume portion adjustable to contain a measured portion of a specific patient's inspiratory volume capacity. Methods of using the device are also provided.
摘要翻译：呼吸肌耐力训练装置（RMET）包括腔室和患者接口。在一个实施方式中，CO 2传感器或温度传感器中的一个或两个可以耦合到腔室或患者接口，以向使用者或护理人员提供关于CO 2 2 / >腔室或患者接口的水平或温度，和/或装置的使用持续时间。在另一实施方式中，RMET可以具有可调整的固定的体积部分以包含特定患者的吸气量容量的测量部分。还提供了使用该设备的方法。

9. 发明申请

WO2003080162A1 INDICATING DEVICE FOR AEROSOL CONTAINER 审中-公开
标题翻译：指示航空集装箱装置
公开(公告)号：WO2003080162A1
公开(公告)日：2003-10-02
申请号：PCT/IB2003/001032
申请日：2003-03-20
申请人： TRUDELL MEDICAL INTERNATIONAL
发明人： SCARROTT, Peter, Mykola
IPC分类号： A61M15/00
CPC分类号： A61M15/009 , A61M15/0068 , A61M15/0073 , A61M15/0075
摘要： An indicating device suitable for indicating the number of metered dosages that have been dispensed from or remain in a container including a base member (40), a cap member (20) moveably connected to the base member (40), an indicator member (60) rotatably mounted to one of the cap member (20) and base member (40) and a drive member (86). The indicator member (60) comprises a first stop member (3004), and the drive member (86) comprises a second stop member (3002). The first stop member (3004) engages the second stop member (3002) as the indicator member (60) is moved to the final position. The engagement between the first and second stop members (3004, 3002) prevents the drive member (86) from being rotated about the second axis. In another preferred embodiment, an inhalation device for dispensing metered dosages of medicaments from a container includes a container having a predetermined number of metered doses and the indicating device. A method for indicating the number of metered dosages of medicaments dispensed from or remaining in the container is also provided.
摘要翻译：一种指示装置，适于指示已经从或从其中分配或保留在容器中的计量剂量的数量，所述容器包括基部构件（40），可移动地连接到基座构件（40）的盖构件（20），指示构件）可旋转地安装到盖构件（20）和基座构件（40）中的一个以及驱动构件（86）上。指示器构件（60）包括第一止动构件（3004），并且驱动构件（86）包括第二止动构件（3002）。随着指示器构件（60）移动到最终位置，第一止动构件（3004）接合第二止动构件（3002）。第一和第二止动构件（3004,3002）之间的接合防止驱动构件（86）围绕第二轴线旋转。在另一个优选实施例中，用于从容器分配计量剂量的药物的吸入装置包括具有预定数量的计量剂量的容器和指示装置。还提供了一种用于指示从容器中分配或保留在容器中的计量剂量的计量剂量的方法。

10. 发明申请

WO2002096490A2 MEDICAMENT APPLICATOR 审中-公开
标题翻译：医学应用者
公开(公告)号：WO2002096490A2
公开(公告)日：2002-12-05
申请号：PCT/IB2002/001650
申请日：2002-05-14
申请人： TRUDELL MEDICAL INTERNATIONAL
发明人： ENGELBRETH, Daniel, K. , FOLEY, Martin, P. , GRYCHOWSKI, Jerry , MORTON, Robert
IPC分类号： A61M15/00
CPC分类号： G01F13/00 , A61M15/0068 , A61M15/0075 , A61M15/009 , A61M15/08 , B05B11/0037 , B05B11/3056 , B05B11/308 , B65D83/386
摘要： An actuator is used to dispense a medicament from a container having at least a first and second portion. The actuator includes a holder, a trigger member and a push member. The holder is adapted to engage at least the first portion of the container. The trigger member is pivotally connected to the holder at a pivot axis, wherein the trigger member is pivotable about the pivot axis in a first direction toward the grippable portion and a second direction opposite the first direction. The push member is connected to the trigger member, wherein the push member is pivotable about the pivot axis in the first direction as the trigger member is pivoted in the first direction and wherein the push member is pivotable about the pivot axis in the second direction as the trigger member is pivoted in the second direction. The push member is adapted to move at least the second portion of the container relative to the holder as the push member is pivoted in the first direction. In one preferred embodiment, the trigger member follows a path, and a stop member engages one of the container and push member and immobilizes the push member as the trigger is moved along a predetermined portion of the path. In one preferred embodiment, a trip member engages the stop member and disengages it from one of the container and the push member, thereby allowing the push member to move the second portion of the container. In one preferred embodiment, the actuator includes an indicator mechanism for indicating the number of doses remaining in or dispensed from the container. A method of dispensing medicament from the container, and a method of assembling the actuator also are provided. A nasal applicator is also provided, and includes a diffuser having a passageway comprising a tapered portion.
摘要翻译：致动器100用于从具有至少第一和第二部分的容器5分配药物。致动器包括保持器102，触发器构件120和推动构件430.保持器适于接合容器的至少第一部分。触发构件在枢转轴线156处枢转地连接到保持器，其中触发构件可绕第一方向围绕枢转轴线朝向可抓握部分枢转，而第二方向可绕第一方向枢转。推动构件连接到触发构件，其中当触发构件沿第一方向枢转时，推动构件可围绕枢转轴线在第一方向上枢转，并且其中推动构件可绕第二方向的枢转轴线枢转，如触发构件在第二方向上枢转。在一个优选实施例中，触发构件遵循路径，并且止动构件604接合容器和推动构件中的一个，并且在触发器沿着路径的预定部分移动时固定推动构件。在一个优选实施例中，跳闸构件608接合止动构件并将其从容器和推动构件中的一个脱离，从而允许推动构件移动容器的第二部分。在一个优选实施例中，致动器包括用于指示剩余在容器中或从容器分配的9个剂量的指示器机构500。提供了从容器分配药物的方法以及组装致动器的方法。还提供鼻施用器，并且包括具有包括锥形部分30的通道的扩散器20。

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