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1. 发明申请

WO9961095A9 PROTECTED PIN CONNECTOR FOR AN ELECTROPHYSIOLOGY CATHETER 审中-公开
标题翻译：用于电生理学导管的受保护的管脚连接器
公开(公告)号：WO9961095A9
公开(公告)日：2000-07-20
申请号：PCT/US9905521
申请日：1999-03-12
申请人： CARDIMA INC
发明人： BARAJAS VICTOR J , DICKENS DUANE
IPC分类号： A61B5/0428 , A61M25/18 , A61N1/05 , A61B17/39 , H01R13/52
CPC分类号： A61B5/04286 , A61N1/05 , Y10S439/909
摘要： A connection system which has particular advantages in medical devices such as electrophysiology catheters, and which minimizes the potential for unwanted electrical connections. A cable of the invention has a plurality of leads, with each lead terminated by a pin connector having a retractable insulative sheath so that the chance of unwanted electrical connections is minimized when the pin connector is not connected. The metal pin of the pin connector also has a nonconducting tip member to minimize the chance of short circuits.
摘要翻译：这种连接系统在诸如电生理学导管的医疗设备中具有特别的优势，并且可以最大限度地减少不需要的电连接的可能性。本发明的电缆具有多根引线，每根引线由具有可伸缩绝缘护套的针式连接器端接，从而当针式连接器未连接时，不希望的电连接的机会被最小化。引脚连接器的金属引脚还具有不导电尖端构件，以尽量减少短路的可能性。

2. 发明申请

WO2010141244A2 SYSTEM AND METHOD FOR PERFORMING ABLATION AND OTHER MEDICAL PROCEDURES USING AN ELECTRODE ARRAY WITH FLEXIBLE CIRCUIT 审中-公开
标题翻译：使用具有柔性电路的电极阵列执行排除和其他医疗程序的系统和方法
公开(公告)号：WO2010141244A2
公开(公告)日：2010-12-09
申请号：PCT/US2010/035798
申请日：2010-05-21
申请人： CARDIMA, INC. , CHAN, Eric K. Y. , BELMAN, Yuri
发明人： CHAN, Eric K. Y. , BELMAN, Yuri
IPC分类号： A61B1/005 , A61B1/012
CPC分类号： A61B18/1492 , A61B5/0422 , A61B2017/00084 , A61B2018/0016 , A61B2018/00702 , A61B2018/00791 , A61B2018/00797 , A61B2018/00821 , A61B2018/00875
摘要： A probe for use in medical procedures includes a longitudinal member, a flexible sheath, and a flexible circuit. The longitudinal member includes at least one electrode and at least one thermocouple disposed thereon. The flexible sheath is coupled to and at least partially surrounding the longitudinal member. The flexible circuit is coupled to the sheath and also to the at least one electrode and the at least one thermocouple. The flexible circuit is configured to provide power to the at least one electrode and a return path to the at least one thermocouple.
摘要翻译：用于医疗程序的探针包括纵向构件，柔性护套和柔性电路。纵向构件包括至少一个电极和设置在其上的至少一个热电偶。柔性护套耦合到并且至少部分地围绕纵向构件。柔性电路耦合到外壳以及至少一个电极和至少一个热电偶。柔性电路被配置为向至少一个电极提供电力，并且向至少一个热电偶提供返回路径。

3. 发明申请

WO2005112809A3 A SYSTEM AND METHOD FOR MULTI-CHANNEL RF ENERGY DELIVERY WIH COAGULUM REDUCTION 审中-公开
标题翻译：一种用于多通道RF能量递送的系统和方法
公开(公告)号：WO2005112809A3
公开(公告)日：2007-02-22
申请号：PCT/US2005016455
申请日：2005-05-11
申请人： CARDIMA INC , NASAB MICHAEL , CHAN ERIC K Y
发明人： NASAB MICHAEL , CHAN ERIC K Y
IPC分类号： A61B18/18 , A61B18/12 , A61B18/14
CPC分类号： A61B18/1492 , A61B18/1206 , A61B2018/0016 , A61B2018/00357 , A61B2018/00648 , A61B2018/00678 , A61B2018/00702 , A61B2018/00791 , A61B2018/00797 , A61B2018/00827 , A61B2018/00875 , A61B2018/00892 , A61B2018/1253 , A61B2018/1467
摘要： A system and method for efficient delivery of radio frequency (RF) energy includes a backplane. At least a single channel card is removably coupled to the backplane for controlling the amount of RF power delivered through a single channel via an electrical coupling to at least one ablation electrode or a catheter. The at least one channel card provides a gradual increase in RF power calculated in real-time during an initial ramp-up phase, and to limit the delivery of RF power through the electrical coupling based on a received temperature of cardiac tissue in contact with the at least one ablation electrode, thereby reducing the likelihood coagulum formation.
摘要翻译：用于射频（RF）能量的有效传送的系统和方法包括背板。至少单通道卡可移除地耦合到背板，用于通过电耦合到至少一个消融电极或导管来控制通过单个通道输送的RF功率的量。所述至少一个通道卡提供在初始加速阶段期间实时计算的RF功率的逐渐增加，并且基于接收到的心脏组织的接收温度来限制通过电耦合的RF功率的传递至少一个消融电极，从而减少凝块形成的可能性。

4. 发明申请

WO1997037607A3 LINEAR ABLATION DEVICE AND ASSEMBLY 审中-公开
公开(公告)号：WO1997037607A3
公开(公告)日：1997-10-16
申请号：PCT/US1997005714
申请日：1997-04-08
申请人： CARDIMA, INC.
发明人： CARDIMA, INC. , SCHAER, Alan, K.
IPC分类号： A61B17/39
摘要： An intravascular device for the formation of linear lesions which has particular utility in the treatment of atrial fibrillation and flutter. The intravascular device has an outer delivery sheath (11) with a distal section (25) which has an elongated opening (28) and a support member (26) coextending with the opening (28). An EP device (12) having a plurality of electrodes (32) on its distal portion (31) is slidably disposed within the inner lumen (13) of the delivery sheath (11) but it is secured by its distal end within the distal extremity of the delivery sheath (11) at least while in operation. In this manner an axial force in the distal direction on the proximal extremity of the EP device (12), which extends out of the patient during the procedure, will cause the distal portion of the EP device (12) to arch outwardly out of and away from the distal section (25) of the delivery sheath (11) and engage the surface of the patient's heart chamber. High frequency, e.g. RF, electrical energy delivered to the electrodes (32) on the distal shaft section (31) of the EP device (12) will form a linear lesion which terminates the fibrillation or flutter.

5. 发明申请

WO2006052905A2 SYSTEM AND METHOD FOR PERFORMING ABLATION AND OTHER MEDICAL PROCEDURES USING AN ELECTRODE ARRAY WITH FLEX CIRCUIT 审中-公开
标题翻译：用柔性电路使用电极阵列执行排除和其他医疗程序的系统和方法
公开(公告)号：WO2006052905A2
公开(公告)日：2006-05-18
申请号：PCT/US2005/040324
申请日：2005-11-08
申请人： CARDIMA, INC. , CHAN, Eric, K., Y. , VEGH, Gabriel
发明人： CHAN, Eric, K., Y. , VEGH, Gabriel
IPC分类号： A61B18/14
CPC分类号： A61B18/1492 , A61B2017/00084
摘要： An ablation catheter having distal and proximal ends for performing ablation on a human tissue region comprises at least one electrode. These elements are formed on a conductive sheet situated at the distal end of the catheter. A flex circuit assembly couples the at least one electrode to a measurement and power circuit attached to the proximal end of the catheter. The measurement and power circuit supplies power to the at least one electrode via the flex circuit.
摘要翻译：具有用于在人体组织区域进行消融的远端和近端的消融导管包括至少一个电极。这些元件形成在位于导管远端的导电片上。柔性电路组件将至少一个电极耦合到附接到导管的近端的测量和电源电路。测量和电源电路通过柔性电路向至少一个电极供电。

6. 发明申请

WO2005112809A2 A SYSTEM AND METHOD FOR MULTI-CHANNEL RF ENERGY DELIVERY WIH COAGULUM REDUCTION 审中-公开
标题翻译：用于多通道RF能量递送的系统和方法
公开(公告)号：WO2005112809A2
公开(公告)日：2005-12-01
申请号：PCT/US2005/016455
申请日：2005-05-11
申请人： CARDIMA, INC. , NASAB, Michael , CHAN, Eric, K.Y.
发明人： NASAB, Michael , CHAN, Eric, K.Y.
IPC分类号： A61B18/14
CPC分类号： A61B18/1492 , A61B18/1206 , A61B2018/0016 , A61B2018/00357 , A61B2018/00648 , A61B2018/00678 , A61B2018/00702 , A61B2018/00791 , A61B2018/00797 , A61B2018/00827 , A61B2018/00875 , A61B2018/00892 , A61B2018/1253 , A61B2018/1467
摘要： A system and method for efficient delivery of radio frequency (RF) energy includes a backplane. At least a single channel card is removably coupled to the backplane for controlling the amount of RF power delivered through a single channel via an electrical coupling to at least one ablation electrode or a catheter. The at least one channel card provides a gradual increase in RF power calculated in real-time during an initial ramp-up phase, and to limit the delivery of RF power through the electrical coupling based on a received temperature of cardiac tissue in contact with the at least one ablation electrode, thereby reducing the likelihood coagulum formation.
摘要翻译：用于射频（RF）能量的有效传送的系统和方法包括背板。至少单通道卡可拆卸地耦合到背板，用于通过电耦合到至少一个消融电极或导管来控制通过单个通道输送的RF功率的量。所述至少一个通道卡提供在初始加速阶段期间实时计算的RF功率的逐渐增加，并且基于接收到的心脏组织的接收温度来限制通过电耦合的RF功率的传递至少一个消融电极，从而减少凝块形成的可能性。

7. 发明申请

WO1998006451A1 INTRALUMINAL DELIVERY OF TISSUE LYSING MEDIUM 审中-公开
标题翻译：组织LISIN MEDIUM的腹腔内递送
公开(公告)号：WO1998006451A1
公开(公告)日：1998-02-19
申请号：PCT/US1997014071
申请日：1997-08-11
申请人： CARDIMA, INC.
发明人： CARDIMA, INC. , MORLEY, Tracey, A. , WANG, Paul, J.
IPC分类号： A61M25/10
CPC分类号： A61M25/104 , A61B18/02 , A61B18/06 , A61B2017/22038 , A61B2017/22067 , A61B2018/00839 , A61B2018/0212 , A61M25/10 , A61M2025/1079 , A61M2025/1093 , A61N2001/0585
摘要： A method and system for lysing a patient's heart tissue causing or involved with arrhythmia which includes an intravascular catheter with a relatively inelastic occlusion balloon on the distal end of the catheter which is inflated to block an artery or vein of the patient's heart so than when lysing fluid such as an ethanol solution is discharged from the distal port in the catheter the inflated balloon prevents the proximal refluxing of lysing medium into undesirable areas of the patient's heart. The inelastic balloon is configured to be inflated to a diameter of about 0.7 to about 1.3, preferably about 0.8 to about 1.2, times the diameter of the blood vessel in which the balloon is to be inflated so as to effectively occlude the passageway without damaging the wall of the blood vessel. The working length of the balloon is less than about 1.5 cm, preferably less than 0.75 cm.
摘要翻译：一种用于裂解引起或参与心律失常的患者心脏组织的方法和系统，其包括在导管的远端上具有相对非弹性闭塞气囊的血管内导管，其被充气以阻塞患者心脏的动脉或静脉，而不是在裂解时诸如乙醇溶液的流体从导管中的远端口排出，充气气球防止裂解介质的近端回流进入患者心脏的不期望的区域。非弹性球囊被构造成充气至球囊膨胀的血管的直径的约0.7至约1.3，优选约0.8至约1.2倍的直径，以便有效地闭塞通道而不损伤血管壁。球囊的工作长度小于约1.5厘米，优选小于0.75厘米。

8. 发明申请

WO9737607A2 LINEAR ABLATION DEVICE AND ASSEMBLY 审中-公开
标题翻译：线性消除装置和装配
公开(公告)号：WO9737607A2
公开(公告)日：1997-10-16
申请号：PCT/US9705714
申请日：1997-04-08
申请人： CARDIMA INC
发明人： SCHAER ALAN K
IPC分类号： A61N1/05 , A61B18/12 , A61B18/14 , A61M25/00 , A61M25/01 , A61N1/40 , A61B17/14
CPC分类号： A61M25/0138 , A61B18/1492 , A61B2018/00029 , A61B2018/0016 , A61B2018/00577 , A61B2018/00797 , A61B2018/00821 , A61M25/0144 , A61M25/0147 , A61M25/0152 , A61N1/403
摘要： An intravascular device for the formation of linear lesions which has particular utility in the treatment of atrial fibrillation and flutter. The intravascular device has an outer delivery sheath (11) with a distal section (25) which has an elongated opening (28) and a support member (26) coextending with the opening (28). An EP device (12) having a plurality of electrodes (32) on its distal portion (31) is slidably disposed within the inner lumen (13) of the delivery sheath (11) but it is secured by its distal end within the distal extremity of the delivery sheath (11) at least while in operation. In this manner an axial force in the distal direction on the proximal extremity of the EP device (12), which extends out of the patient during the procedure, will cause the distal portion of the EP device (12) to arch outwardly out of and away from the distal section (25) of the delivery sheath (11) and engage the surface of the patient's heart chamber. High frequency, e.g. RF, electrical energy delivered to the electrodes (32) on the distal shaft section (31) of the EP device (12) will form a linear lesion which terminates the fibrillation or flutter.
摘要翻译：用于形成线性损伤的血管内装置，其特别用于治疗房颤和扑动。血管内装置具有外部输送护套（11），其具有远侧部分（25），其具有细长开口（28）和与开口（28）共同延伸的支撑构件（26）。在其远侧部分（31）上具有多个电极（32）的EP装置（12）可滑动地设置在输送护套（11）的内腔（13）内，但是其远端端部固定在远端至少在操作时输送护套（11）。以这种方式，EP过程中从患者身体延伸出来的EP装置（12）的近端上的远侧方向上的轴向力将导致EP装置（12）的远端部分向外伸出和远离输送护套（11）的远端部分（25）并且接合患者心脏腔室的表面。高频率，例如 RF，传送到EP装置（12）的远侧轴部分（31）上的电极（32）的电能将形成终止原纤维或颤动的线性损伤。

9. 发明申请

WO1996040342A1 GUIDING CATHETER FOR CORONARY SINUS 审中-公开
标题翻译：指南针
公开(公告)号：WO1996040342A1
公开(公告)日：1996-12-19
申请号：PCT/US1996009283
申请日：1996-06-05
申请人： CARDIMA, INC.
发明人： CARDIMA, INC. , RANDOLPH, Yvonne , DICKENS, Duane
IPC分类号： A61M25/00
CPC分类号： A61M29/02 , A61B18/1492 , A61M25/0041 , A61M25/0054 , A61M25/0141 , A61M25/0152 , A61M25/0662 , A61M2025/0081 , A61M2025/1052 , A61M2210/125 , A61N1/056 , A61N1/057
摘要： A guiding catheter for delivery of intravascular devices to a patient's coronary sinus. The guiding catheter has a relatively stiff proximal section and a relatively flexible distal section, the latter being about 1 to about 6 inches in length and being configured to subselect a branch cardiac vein leading to the coronary sinus. The guiding catheter is particularly suitable for delivering an intravascular device for sensing electrical activity into a cardiac vein to detect such activity from within the blood vessel.
摘要翻译：用于将血管内装置输送到患者的冠状窦的引导导管。引导导管具有相对刚性的近端部分和相对柔性的远端部分，后端部分的长度为约1至约6英寸，并且构造成分选通向冠状窦的分支心静脉。引导导管特别适用于将用于感测电活动的血管内装置输送到心静脉以从血管内检测这种活动。

10. 发明申请

WO2010141244A3 SYSTEM AND METHOD FOR PERFORMING ABLATION AND OTHER MEDICAL PROCEDURES USING AN ELECTRODE ARRAY WITH FLEXIBLE CIRCUIT 审中-公开
标题翻译：使用柔性电路的电极阵列执行排除和其他医疗程序的系统和方法
公开(公告)号：WO2010141244A3
公开(公告)日：2011-03-10
申请号：PCT/US2010035798
申请日：2010-05-21
申请人： CARDIMA INC , CHAN ERIC K Y , BELMAN YURI
发明人： CHAN ERIC K Y , BELMAN YURI
IPC分类号： A61B1/005 , A61B1/012
CPC分类号： A61B18/1492 , A61B5/0422 , A61B2017/00084 , A61B2018/0016 , A61B2018/00702 , A61B2018/00791 , A61B2018/00797 , A61B2018/00821 , A61B2018/00875
摘要： A probe for use in medical procedures includes a longitudinal member, a flexible sheath, and a flexible circuit. The longitudinal member includes at least one electrode and at least one thermocouple disposed thereon. The flexible sheath is coupled to and at least partially surrounding the longitudinal member. The flexible circuit is coupled to the sheath and also to the at least one electrode and the at least one thermocouple. The flexible circuit is configured to provide power to the at least one electrode and a return path to the at least one thermocouple.
摘要翻译：用于医疗过程的探针包括纵向构件，柔性护套和柔性电路。纵向构件包括至少一个电极和设置在其上的至少一个热电偶。柔性护套耦合到并且至少部分地围绕纵向构件。柔性电路耦合到外壳以及至少一个电极和至少一个热电偶。柔性电路被配置为向至少一个电极提供电力，并且向至少一个热电偶提供返回路径。

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