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    • 4. 发明申请
    • MULTI-CHANNEL RF ENERGY DELIVERY WITH COAGULUM REDUCTION
    • 多通道射频能量消耗减少
    • WO0187172A9
    • 2003-01-03
    • PCT/US0115346
    • 2001-05-14
    • CARDIMA INCNASAB MOHSENCHAN ERIC K Y
    • NASAB MOHSENCHAN ERIC K Y
    • A61B18/12A61B18/14
    • A61B18/1492A61B18/1206A61B2018/0016A61B2018/00357A61B2018/00648A61B2018/00678A61B2018/00702A61B2018/00791A61B2018/00797A61B2018/00827A61B2018/00875A61B2018/00892A61B2018/1253A61B2018/1467
    • A system for efficient delivery of radio frequency (RF) energy to cardiac tissue with an ablation catheter used in catheter ablation, with new concepts regarding the interaction between RF energy and biological tissue. In addition, new insights into methods for coagulum reduction during RF ablation will be presented, and a quantitative model for ascertaining the propensity for coagulum formation during RF ablation will be introduced. Effective practical techniques are presented for multichannel simultaneous RF energy delivery with real-time calculation of the Coagulum Index, which estimates the probability of coagulum formation. This information is used in a feedback and control algorithm which effectively reduces the probability of coagulum formation during ablation. For each ablation channel, electrical coupling delivers an RF electrical current through an ablation electrode of the ablation catheter and a temperature sensor is positioned relative to the ablation electrode for measuring the temperature of cardiac tissue in contact with the ablation electrode. A current sensor is provided within each channel circuitry for measuring the current delivered through said electrical coupling and an information processor and RF output controller coupled to said temperature sensor and said current sensor for estimating the likelihood of coagulum formation. When this functionality is propagated simultaneously through multiple ablation channels, the resulting linear or curvilinear lesion is deeper with less gaps. Hence, the clinical result is improved due to improved lesion integrity.
    • 用于在导管消融中使用的消融导管将射频(RF)能量有效地递送到心脏组织的系统,其中关于RF能量和生物组织之间的相互作用的新概念。 此外,将介绍在射频消融期间减少凝固物的方法的新见解,并且将介绍用于确定射频消融期间凝结物形成倾向的定量模型。 提出了有效的实际技术,用于多通道同时射频能量传递,实时计算凝聚指数,可以估计凝结物形成的可能性。 该信息用于反馈和控制算法,可有效降低消融期间凝块形成的可能性。 对于每个消融通道,电耦合将RF电流传递通过消融导管的消融电极,并且相对于消融电极定位温度传感器,用于测量与消融电极接触的心脏组织的温度。 在每个通道电路内提供电流传感器,用于测量通过所述电耦合传递的电流,以及耦合到所述温度传感器和所述电流传感器的信息处理器和RF输出控制器,用于估计凝结物形成的可能性。 当这种功能通过多个消融通道同时传播时,所得到的线性或曲线病变在较短的间隙下更深。 因此,由于改善的病变完整性,临床结果得到改善。