专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

81. 发明申请

WO1994009719A1 DEPTH GAUGE AND METHOD OF TREATING A DEPTH GAUGE 审中-公开
标题翻译：深度计和深度计的处理方法
公开(公告)号：WO1994009719A1
公开(公告)日：1994-05-11
申请号：PCT/SE1993000870
申请日：1993-10-25
申请人： AKTIEBOLAGET ASTRA , BERGSTRÖM, Nils, Gustaf , BROBERG, Leif , HOLMEN, Anders
发明人： AKTIEBOLAGET ASTRA
IPC分类号： A61C19/04
CPC分类号： A61C8/0089 , A61C19/04
摘要： The present invention relates to a device for determining the correct lengths of standardized components of a dental implant system in situ in the oral cavity. The device comprises an elongate gauge body (1, 2) being provided with circumferential dark bands (10, 18, 19, 20, 21) located at predetermined distances from each other and having predetermined widths, the areas between said darker bands having a pronouncedly lighter colour, each boundary line between lighter and darker bands corresponding to one specific, standardized component.
摘要翻译：本发明涉及用于在口腔内原位确定牙科植入物系统的标准化部件的正确长度的装置。该装置包括细长的测量体（1,2），其具有位于彼此预定距离并且具有预定宽度的周向暗带（10,18,19,20,21），所述较暗带之间的区域具有明显的较浅的颜色，较浅和较暗带之间的每个边界线对应于一个特定的标准化组件。

82. 发明申请

WO1993025669A1 DNA SEQUENCES USED IN THE PRODUCTION OF RECOMBINANT HUMAN BSSL/CEL IN TRANSGENIC NON-HUMAN MAMMALS, AND THE PRODUCED BSSL/CEL USED IN INFANT FORMULAS 审中-公开
标题翻译：用于生产重组人BSSL / CEL在转基因非人类哺乳动物中使用的DNA序列以及用于婴儿配方的生产的BSSL / CEL
公开(公告)号：WO1993025669A1
公开(公告)日：1993-12-23
申请号：PCT/SE1993000515
申请日：1993-06-09
申请人： AKTIEBOLAGET ASTRA
发明人： AKTIEBOLAGET ASTRA , BJURSELL, Karl, Gunnar , CARLSSON, Peter, Nils, Ivar , ENERBÄCK, Curt, Sven, Magnus , HANSSON, Stig, Lennart , LIDBERG, Ulf, Fredrik, Pontus , NILSSON, Jeanette, Annika , TÖRNELL, Jan, Birger, Fredrik
IPC分类号： C12N09/20
CPC分类号： C12N15/8509 , A01K67/0278 , A01K2207/15 , A01K2217/00 , A01K2217/05 , A01K2227/10 , A01K2227/105 , A01K2267/01 , A23C9/20 , A61K38/00 , C12N9/20 , C12N2830/008
摘要： The present invention relates to a DNA molecule containing intron sequences and encoding a human protein which is, depending on the site of action, called Bile Salt-Stimulated Lipase (BSSL) or Carboxyl Ester Lipase (CEL). The DNA molecule is advantageously used in the production of recombinant human BSSL/CEL, preferably by means of production in transgenic non-human mammals. The recombinant human BSSL/CEL can be used as a constituent of infant formulas used for feeding infants as a substitute for human milk, or in the manufacture of medicaments against e.g. fat malabsorption, cystic fibrosis and chronic pancreatitis.
摘要翻译：本发明涉及含有内含子序列和编码人蛋白质的DNA分子，其取决于作用部位称为胆汁盐刺激脂肪酶（BSSL）或羧基酯脂肪酶（CEL）。 DNA分子有利地用于生产重组人BSSL / CEL，优选通过在转基因非人哺乳动物中的生产。重组人BSSL / CEL可以用作婴儿配方的成分，用于喂养婴儿作为人乳的替代品，或者用于制备药物。脂肪吸收不良，囊性纤维化和慢性胰腺炎。

83. 发明申请

WO1993024164A1 ARRANGEMENT AND METHOD FOR DISPENSING PRESERVATIVE-FREE NASAL SPRAYS AND SIMILAR PREPARATIONS 审中-公开
标题翻译：用于分配无保护性NASAL喷雾和类似制剂的布置和方法
公开(公告)号：WO1993024164A1
公开(公告)日：1993-12-09
申请号：PCT/SE1993000485
申请日：1993-06-01
申请人： AKTIEBOLAGET ASTRA , NILSON, Kurt
发明人： AKTIEBOLAGET ASTRA
IPC分类号： A61M11/00
CPC分类号： A61M15/08 , A61M15/0025
摘要： The invention relates to a method for keeping the dispensing parts on a device for administering a sterile preparation for local treatment containing a preservative-free preparation free from bacterial growth. This is achieved in that the dispensing part is allowed to dry quickly after each use. The invention is also directed towards a cap to be used in this method. The cap (6) is provided with means allowing the dispensing part to dry quickly, such as openings (7, 8) and/or absorbent materials (18') at least partly facing the ambient air.
摘要翻译：本发明涉及一种用于将分配部件保持在用于施用用于局部治疗的无菌制剂的装置上的方法，其包含不含细菌生长的无防腐剂的制剂。这是因为在每次使用后允许分配部件快速干燥。本发明还涉及在该方法中使用的盖。盖（6）设置有允许分配部件快速干燥的装置，例如至少部分地面向环境空气的开口（7,8）和/或吸收材料（18'）。

84. 发明申请

WO1993024079A1 KNEE JOINT PROSTHESIS 审中-公开
公开(公告)号：WO1993024079A1
公开(公告)日：1993-12-09
申请号：PCT/SE1993000451
申请日：1993-05-19
申请人： AKTIEBOLAGET ASTRA , ALBREKTSSON, Björn , CARLSSON, Lars, Valter , JACOBSSON, Carl, Magnus, Gösta , RÖSTLUND, Tord, Valter , WENNBERG, Stig
发明人： AKTIEBOLAGET ASTRA
IPC分类号： A61F02/38
CPC分类号： A61F2/3859 , A61F2002/3863 , A61F2002/3895
摘要： The invention relates to a joint prosthesis for permanent anchorage in the bone tissue of one of the articulatory parts of a joint in a human body, in particular the femur side of a knee joint, primarily intended to be fitted in one operation only. The prosthesis comprises an attachment part (1), intended to be anchored in the human bone tissue by means of a fixture (8), and an articulation element (2) adapted to fit the attachment part (1). The articulation element is attached to the attachment part by a combination of complementary shapes (27, 28, 33, 34) and snap-action locking means (31).
摘要翻译：本发明涉及一种用于在人体内，尤其是膝关节的股骨侧的关节部分之一的骨组织中永久性锚固的关节假体，主要仅适用于一次手术。假体包括通过固定装置（8）锚定在人骨组织中的附接部分（1）和适于装配附接部分（1）的关节元件（2）。铰接元件通过互补形状（27,28,33,34）和卡扣动作锁定装置（31）的组合附接到附接部分。

85. 发明申请

WO1993022990A1 JOINT PROSTHESIS AND APPARATUS FOR PREPARING THE BONE PRIOR TO FITTING OF THE PROSTHESIS 审中-公开
标题翻译：联合预防和预防接种前使用骨髓的装置
公开(公告)号：WO1993022990A1
公开(公告)日：1993-11-25
申请号：PCT/SE1993000427
申请日：1993-05-14
申请人： AKTIEBOLAGET ASTRA , ABREKTSSON, Björn , CARLSSON, Lars , JACOBSSON, Magnus , RÖSTLUND, Tord , WENNBERG, Stig
发明人： AKTIEBOLAGET ASTRA
IPC分类号： A61F02/38
CPC分类号： A61B17/8605 , A61B17/8625 , A61F2/3868 , A61F2002/30892 , A61F2002/3895
摘要： The invention relates to a prosthesis for uni-condylar or bi-condylar replacement of a joint in a human body and in particular to the tibia side of a knee joint. By means of an elongate fixture, a prosthetic plate is secured in position in a pre-prepared tibia portion and is allowed to heal, without further surgery being required. The invention also relates to a device for preparing the knee joint for prosthetic reception.
摘要翻译：本发明涉及一种用于单髁或双髁更换人体，特别是膝关节胫骨侧的关节的假体。通过细长的固定装置，将假肢板固定在预先制备的胫骨部分中的适当位置，并且允许其愈合，而不需要进一步的手术。本发明还涉及一种用于制备用于假体接收的膝关节的装置。

86. 发明申请

WO1993021980A1 DOSAGE INHALATOR WITH INDICATING/INTERRUPTING MEANS 审中-公开
标题翻译：具有指示/中断手段的剂量吸入器
公开(公告)号：WO1993021980A1
公开(公告)日：1993-11-11
申请号：PCT/SE1993000389
申请日：1993-05-04
申请人： AKTIEBOLAGET ASTRA , TROFAST, Eva, Ann-Christin , WETTERLIN, Kjell, Ingvar, Leopold , VIRTANEN, Risto
发明人： AKTIEBOLAGET ASTRA
IPC分类号： A61M15/00
CPC分类号： A61M15/0068 , A61M15/0066 , A61M2202/064
摘要： The invention relates to a dosage inhalator for dispensing to a patient a pharmacologically active compound or substance suspended in a fluid comprising a nozzle (2), a conduit (3) connected to said nozzle, a storage means (4) adjacent said conduit (3) containing multiple doses of said active compound to be dispensed, a carrying means (5) having portions (6) for carrying predetermined and reproducible unit doses of said active compound, said carrying means being mounted for movement between said conduit (3) and said storage means (4) to position one of said portions (6) in said conduit (3) whereby said unit dose of said active compound located at said portion (6) can be dispensed into the conduit, said carrying means being actuated by means of a maneuvering means (10, 110). The inhalator further comprises means (20) for disrupting the movement of said maneuvering means (10, 110) directly or indirectly upon exhaustion of said active compound in said storage means (4). In an alternative embodiment the inhalator comprises means for indicating either the number of doses remaining in said storage means or the number of doses used, said indicating means comprising a screw and nut mechanism being rotated by said intermittent movement of said carrying means, the relative movement between the screw (16) and the nut (17) in said mechanism being caused by said rotation being used for actuating said indicating means.
摘要翻译：本发明涉及一种用于向患者分配悬浮在流体中的药理活性化合物或物质的剂量吸入器，其包括喷嘴（2），连接到所述喷嘴的导管（3），与所述导管（3）相邻的存储装置（4）），包含多个剂量的待分配的所述活性化合物的载体装置（5），其具有用于承载预定和可再现的单位剂量的所述活性化合物的部分（6），所述携带装置安装成在所述导管（3）和所述存储装置（4）将所述部分（6）中的一个定位在所述导管（3）中，由此位于所述部分（6）处的所述活性化合物的单位剂量可以被分配到导管中，所述携带装置通过操纵装置（10,110）。吸入器还包括用于在所述存储装置（4）中排出所述活性化合物时直接或间接地中断所述操纵装置（10,110）运动的装置（20）。在替代实施例中，吸入器包括用于指示所述存储装置中剩余的剂量数量或使用的剂量数量的装置，所述指示装置包括通过所述携带装置的所述间歇运动而旋转的螺钉和螺母机构，所述相对运动在所述机构中的螺钉（16）和螺母（17）之间由所述旋转引起的用于致动所述指示装置。

87. 发明申请

WO1993021948A1 PEPTIDE-CARBOHYDRATE CONJUGATES GENERATING T-CELL IMMUNITY 审中-公开
标题翻译：肽 - 碳水化合物产生T细胞免疫
公开(公告)号：WO1993021948A1
公开(公告)日：1993-11-11
申请号：PCT/SE1993000353
申请日：1993-04-23
申请人： AKTIEBOLAGET ASTRA
发明人： AKTIEBOLAGET ASTRA , JONDAL, Mikael
IPC分类号： A61K39/00
CPC分类号： C07H15/18 , A61K39/385 , A61K2039/605 , A61K2039/627 , C07H15/04 , C07K9/00 , C07K9/001 , C07K14/005 , C12N2760/16122
摘要： The present invention relates to a novel class of biologically active compounds, to processes for their production and to their use in therapy. More particularly the invention provides immunogenic conjugates useful for generating T cell immunity against tumor-associated carbohydrate structures or against carbohydrate structures expressed on infectious agents and/or infected host cells. The said immunogenic conjugate comprises (i) a peptide component capable of binding an MHC class I molecule; and (ii) a carbohydrate component having the immunogenic specificity of said carbohydrate structure.
摘要翻译：本发明涉及新一类生物活性化合物，用于其生产方法及其在治疗中的应用。更具体地，本发明提供了可用于产生针对肿瘤相关碳水化合物结构的T细胞免疫或针对在感染因子和/或感染的宿主细胞上表达的碳水化合物结构的免疫原性缀合物。所述免疫原性缀合物包含（i）能够结合MHC I类分子的肽组分; 和（ii）具有所述碳水化合物结构的免疫原性特异性的碳水化合物组分。

88. 发明申请

WO1993008775A1 AIR PRESSURE GENERATOR 审中-公开
标题翻译：空气压力发生器
公开(公告)号：WO1993008775A1
公开(公告)日：1993-05-13
申请号：PCT/SE1992000755
申请日：1992-11-03
申请人： AKTIEBOLAGET ASTRA , HANSSON, Ingvar , HÄLLJE, Per , SAARIO, Roy
发明人： AKTIEBOLAGET ASTRA
IPC分类号： A61F11/00
CPC分类号： A61M13/003 , A61F11/00
摘要： The invention relates to an air pressure generator for generating pressure pulses for the treatment of ears, said pulses being intended to be applied for instance to the external auditory meatus of an ear, said generator comprising a housing (1, 101, 201, 301) and a flexible membrane (16, 116, 216, 316) located in said housing and means (7, 107, 207, 307, 9, 109, 209, 309) for actuating said membrane. The membrane and said housing form a chamber (24) connected by suitable connecting means (23, 37, 40, 41, 35) to the ear (36), said chamber and said connecting means forming a closed system in the working position of the generator, said pressure pulses being generated by the direct action of the displacements of said membrane caused by said actuating means on the enclosed air in said closed system.
摘要翻译：本发明涉及一种用于产生用于治疗耳朵的压力脉冲的空气压力发生器，所述脉冲旨在被施加到例如耳朵的外耳道，所述发生器包括壳体（1,101,201,301）以及位于所述壳体中的柔性膜（16,116,216,316）和用于致动所述膜的装置（7,107,207,307,99,109,309,309）。膜和所述壳体形成通过合适的连接装置（23,37,40,41,35）连接到耳朵（36）的腔室（24），所述腔室和所述连接装置形成在所述压力脉冲是由所述致动装置在所述封闭系统中的封闭空气上引起的所述膜的位移的直接作用产生的。

89. 发明申请

WO1992017477A1 NEW ACTIVE COMPOUNDS 审中-公开
标题翻译：新活性化合物
公开(公告)号：WO1992017477A1
公开(公告)日：1992-10-15
申请号：PCT/SE1992000190
申请日：1992-03-25
申请人： AKTIEBOLAGET ASTRA , BRIVING, Carin , ELEBRING, Marie , CARLSSON, Stig , CARTER, Robert , KÜHLER, Thomas , NORDBERG, Peter , STARKE, Ingemar , SVENSSON, Arne
发明人： AKTIEBOLAGET ASTRA
IPC分类号： C07D471/04
CPC分类号： C07D471/04
摘要： New therapeutically active compounds of formula (I).

90. 发明申请

WO1991018895A1 IMPROVED METHOD FOR SYNTHESIS 审中-公开
标题翻译：改进的合成方法
公开(公告)号：WO1991018895A1
公开(公告)日：1991-12-12
申请号：PCT/SE1991000402
申请日：1991-06-05
申请人： AKTIEBOLAGET ASTRA
发明人： AKTIEBOLAGET ASTRA , BRÄNDSTRÖM, Arne, Elof
IPC分类号： C07D401/12
CPC分类号： C07D401/12
摘要： The present invention relates to an improved method for the synthesis of omeprazole, comprising the steps of reacting 5-methoxy-2-[(4-methoxy-3,5-dimethyl-2-pyridinyl)-methylthio]-1H-benzi midazole with m-chloroperoxy-benzoic acid in a methylene chloride solution at a substantially constant pH of about 8.0 to 8.6; extracting the reaction mixture with aqueous NaOH; separating the aqueous phase from the organic phase; and adding an alkyl formate to the aqueous phase, resulting in crystallization of omeprazole.
摘要翻译：本发明涉及一种用于合成奥美拉唑的改进方法，包括以下步骤：使5-甲氧基-2 - [（4-甲氧基-3,5-二甲基-2-吡啶基） - 甲硫基] -1H-苯并咪唑与间氯过氧苯甲酸在约8.0至8.6的基本恒定的pH下在二氯甲烷溶液中; 用NaOH水溶液萃取反应混合物; 将水相与有机相分离; 并向水相中加入甲酸烷基酯，导致奥美拉唑结晶。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式