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71. 发明申请

WO2009064082A1 COMPOSITION COMPRISING GALLA RHOIS EXTRACT FOR PREVENTION AND TREATMENT OF OBESITY BY MEANS OF AUTOPHAGIC MECHANISM 审中-公开
标题翻译：包含GALLA RHOIS提取物的组合物，用于通过自动机械手段预防和治疗肥胖
公开(公告)号：WO2009064082A1
公开(公告)日：2009-05-22
申请号：PCT/KR2008/006294
申请日：2008-10-24
申请人： IGSBIO , KANG, Se Chan , CHOI, Han , CHEONG, Young Jun , JUNG, Young Hwan , KIM, Hee Jeong , SON, Eun Hwa
发明人： KANG, Se Chan , CHOI, Han , CHEONG, Young Jun , JUNG, Young Hwan , KIM, Hee Jeong , SON, Eun Hwa
IPC分类号： A61K36/22 , A61K31/351 , A61P3/00 , A61K31/70
CPC分类号： A61K36/22 , A61K31/351 , A61K31/70
摘要： The present invention relates to a composition comprising a Galla Rhois extract for the prevention and treatment of obesity based on the mechanism of autophagocytosis. In particular, the present invention has found that the Galla Rhois extract or fraction thereof exhibits inhibitory effects on the proliferation of adipocytes by inducing autophagocytosis thereof, and therefore, provides a method of isolating active ingredients capable of being used as a composition for the prevention and treatment of obesity from Galla Rhois, and a composition for the prevention and treatment of obesity which comprises a Galla Rhois extract or a fraction thereof. That is, the Galla Rhois extract according to the present invention exerts beneficial activities of inducing autophagocytosis of adipocytes in vitro, inhibiting body weight gain in an obesity-induced animal model, reducing the body weight of a body weight gain-induced animal model, and lowering the levels of triglycerides and low density lipoproteins in the blood. Therefore, the Galla Rhois extract according to the present invention can be effectively used as a pharmaceutical composition and health foods for the prevention of obesity and complications thereof and treating the same.
摘要翻译：本发明涉及一种包含根据自噬作用机理预防和治疗肥胖症的加洛氏提取物的组合物。特别地，本发明已经发现，加洛氏提取物或其部分通过诱导其自身吞噬作用而对脂肪细胞的增殖表现出抑制作用，因此，提供了分离能够用作预防和/或免疫的组合物的活性成分的方法治疗来自Galla Rhois的肥胖症，以及用于预防和治疗肥胖症的组合物，其包含加利罗非鱼提取物或其一部分。也就是说，根据本发明的加拉罗氏菌提取物在体外发挥诱导脂肪细胞的自噬作用的有益活性，抑制肥胖诱导的动物模型中的体重增加，减轻体重增加诱导的动物模型的体重，以及降低血液中甘油三酸酯和低密度脂蛋白的含量。因此，根据本发明的加拉罗氏菌提取物可以有效地用作药物组合物和用于预防肥胖及其并发症并进行治疗的保健食品。

72. 发明申请

WO2008055107A3 USE OF COTINUS COGGYGRIA EXTRACT TREATING HEMORRHOIDS 审中-公开
标题翻译：使用COTINUS COGGYGRIA提取物处理HEMORRHOIDS
公开(公告)号：WO2008055107A3
公开(公告)日：2009-02-19
申请号：PCT/US2007082849
申请日：2007-10-29
申请人： JOHNSON & JOHNSON CONSUMER , SEIBERG MIRI , STONE VIOLETTA IOTSOVA , ZHAO RENBIN , BRUNING ELIZABETH
发明人： SEIBERG MIRI , STONE VIOLETTA IOTSOVA , ZHAO RENBIN , BRUNING ELIZABETH
IPC分类号： A61K36/22 , A61K36/06 , A61K36/185 , A61K36/28 , A61K36/45 , A61K36/53
CPC分类号： A61K9/0031 , A61K9/02 , A61K9/06 , A61K9/7007 , A61K33/30 , A61K36/06 , A61K36/185 , A61K36/22 , A61K36/28 , A61K36/45 , A61K36/53 , A61K45/06 , A61K2300/00
摘要： The present invention relates to a method for treating hemorrhoids by topically administering to tissue in need of such treatmenta a composition containing continus coggygria extract.
摘要翻译：本发明涉及通过局部施用需要这种治疗的组织来治疗痔疮的方法，所述组合物含有连续的香草提取物。

73. 发明申请

WO2008150074A3 THE COMPOSITION COMPRISING THE EXTRACTS, FRACTIONS AND THE ISOLATED COMPOUNDS OF RHUS VERNICIFLUA FOR PREVENTION AND TREATMENT OF DIABETIC COMPLICATIONS 审中-公开
标题翻译：包含RHUS VERNICIFLUA预防和治疗糖尿病并发症的提取物，部位和分离化合物的组合物
公开(公告)号：WO2008150074A3
公开(公告)日：2009-01-29
申请号：PCT/KR2008002806
申请日：2008-05-20
申请人： KOREA INST SCI & TECH , JUNG SANG HOON , LEE EUN HA , PAN CHEOL-HO , KIM CHUL YOUNG , UM BYUNG HUN , LEE DONG-UN , SONG DAE GEUN , LEE JOO YOUNG
发明人： JUNG SANG HOON , LEE EUN HA , PAN CHEOL-HO , KIM CHUL YOUNG , UM BYUNG HUN , LEE DONG-UN , SONG DAE GEUN , LEE JOO YOUNG
IPC分类号： A61K36/22 , A61K31/34 , A61P3/00
CPC分类号： A61K36/22 , A61K31/34
摘要： The present invention relates to a composition for prevention and treatment of diabetic complications containing the extracts of Rhus verniciflua, fractions thereof and compounds isolated therefrom as an active ingredient, more precisely a composition for prevention and treatment of diabetic complications which comprises the extracts of Rhus verniciflua extracted by using water, alcohol or a mixture thereof as a solvent, fractions thereof and compounds isolated therefrom as an active ingredient. The extracts of Rhus verniciflua extracted by- using water, alcohol or a mixture thereof as a solvent, fractions thereof and compounds isolated therefrom were confirmed to have inhibitory effect on aldose reductase causing accumulation of sorbitol which is one of major causes of diabetic complications and on advanced glycation end procuct without cytotoxicity, so that they were confirmed to be safe materials effectively used for the composition for prevention and treatment of diabetic complications.
摘要翻译：本发明涉及一种预防和治疗含有紫荆提取物及其分离物及其分离自其中的化合物作为活性成分的糖尿病并发症的组合物，更准确地说，涉及预防和治疗糖尿病并发症的组合物，其包含紫草提取物通过使用水，醇或其混合物作为溶剂萃取，其馏分和作为活性成分从其中分离出的化合物。通过使用水，醇或其混合物作为溶剂提取的Rhus verniciflua的提取物，其级分和从其分离的化合物被证实对引起糖尿病并发症的主要原因之一的山梨糖醇积累的醛糖还原酶具有抑制作用，并且对晚期糖基化终末没有细胞毒性，因此被证实是有效用于预防和治疗糖尿病并发症的组合物的安全材料。

74. 发明申请

WO2008063857A3 ANTIOXIDANT DIETARY SUPPLEMENT COMPOSITIONS AND METHODS FOR MAINTAINING HEALTHY SKIN 审中-公开
公开(公告)号：WO2008063857A3
公开(公告)日：2008-05-29
申请号：PCT/US2007/083696
申请日：2007-11-06
申请人： MOLECULAR RESEARCH CENTER INC. , CHOMCZYNSKI, Piotr
发明人： CHOMCZYNSKI, Piotr
IPC分类号： A23L1/212 , A23L1/30 , A23L2/58 , A61K31/047 , A61K36/81 , A61K36/22
摘要： Compositions and methods for maintaining healthy skin and alleviating skin conditions such as redness, inflammation, irritation and skin aging, as well as for maintaining healthy scalp and hair are disclosed. The oral compositions disclosed comprise antioxidants including lycopene, gallic acid and ascorbic acid. Preferably lycopene containing tomato compositions has been water-extracted, more preferably under acid conditions. In the method of treatment aspect of the invention, an oral composition containing antioxidant(s) is administered to a person concurrently with a topical treatment for said skin conditions. Preferred topical compositions comprise cyclohexane polyols, such as cyclohexanediol or cyclohexanetriol.

75. 发明申请

WO2007046125A3 USE OF EXTRACTS OF MYRTLE AND OTHER MEDITERRANEAN PLANT SPECIES, AS ANTIMYCOTIC AGENT TOWARDS YEAST AND YEAST-LIKE MICROORGANISMS 审中-公开
标题翻译：使用麦芽糖和其他中等植物物种的提取物，作为抗衰老药物，用于年轻和类似微生物
公开(公告)号：WO2007046125A3
公开(公告)日：2007-09-20
申请号：PCT/IT2006000743
申请日：2006-10-17
申请人： ROMANI ANNALISA , BUZZINI PIETRO , CHESSA INNOCENZA , FRANCONI FLAVIA , PINELLI PATRIZIA , TURCHETTI BENEDETTA , NIEDDU GIOVANNI
发明人： ROMANI ANNALISA , BUZZINI PIETRO , CHESSA INNOCENZA , FRANCONI FLAVIA , PINELLI PATRIZIA , TURCHETTI BENEDETTA , NIEDDU GIOVANNI
IPC分类号： A61K36/61 , A61K8/97 , A61K36/15 , A61K36/185 , A61K36/22 , A61K36/45 , A61K36/87 , A61P31/10
CPC分类号： A61K36/185 , A61K36/22 , A61K36/45 , A61K36/61 , A61K2300/00
摘要： The present invention is directed to the preparation of natural extracts of myrtle, cistus, arbutus, lentisk and other Mediterranean plant species extracts (standardized in the content of polyphenolic molecules), isolated both from different plant tissues and by-products deriving from artisan or industrial manufactures carried out on the same species. The utilization of the above extracts as antimycotic agents is related to its activity towards yeast and yeast-like microorganisms of biomedical interest.
摘要翻译：本发明涉及由不同的植物组织和从工匠或工业产生的副产物分离的桃金娘，嫩枝，杨梅，扁豆和其他地中海植物物种提取物（标准化的多酚分子含量）的天然提取物的制备在同一物种上进行制造。上述提取物作为抗真菌剂的利用与其对生物医学兴趣的酵母和酵母样微生物的活性有关。

76. 发明申请

WO2006058017A2 TRANSMUCOSAL ORAL DELIVERY DEVICE 审中-公开
标题翻译：转运口服递送装置
公开(公告)号：WO2006058017A2
公开(公告)日：2006-06-01
申请号：PCT/US2005/042348
申请日：2005-11-21
申请人： IZUN PHARMACEUTICALS CORPORATION , LEVINE, William , SAFFER, Aron
发明人： LEVINE, William , SAFFER, Aron
IPC分类号： A61K36/22
CPC分类号： A61K36/35 , A61K9/006 , A61K9/7007
摘要： Provided, among other things, is a method of treating an indication of mucosal or adjacent tissue comprising periodically applying to mucosa at or adjacent to disease affected tissue a delivery device comprising a backing layer and an adhesive reservoir comprising an effective amount of appropriate composition of plant extract(s) comprising extract of Sambucus nigra, wherein the adhesive reservoir comprises 30 to 70 polymer by weight, of which a major portion comprises polyacrylic polymer, wherein the delivery device is flexible and tissue conforming.
摘要翻译：提供了一种治疗粘膜或相邻组织的指征的方法，其包括在疾病影响组织处或邻近的周期性地施用粘膜，包括背衬层和粘合剂储存器，所述粘附储存器包含有效量的适当的植物组合物提取物，其包含黑梳（Sambucus nigra）的提取物，其中所述粘合剂储存器包含30至70重量份的聚合物，其中主要部分包含聚丙烯酸聚合物，其中所述递送装置是柔性的并且组织符合。

77. 发明申请

WO2005112967A3 ANTICANCER ACTIVITY OF CHIOS MASTIC GUM 审中-公开
标题翻译： CHIOS MASIC GUM的反应活动
公开(公告)号：WO2005112967A3
公开(公告)日：2006-01-26
申请号：PCT/US2005017598
申请日：2005-05-19
申请人： BALFOUR MARKETING CORP , PANTAZIS PANAYOTIS , SITARAS NIKOLAOS , WYCHE JAMES , KELLIS GEORGE
发明人： PANTAZIS PANAYOTIS , SITARAS NIKOLAOS , WYCHE JAMES , KELLIS GEORGE
IPC分类号： A61K36/22 , A61K36/32 , A61K31/00
CPC分类号： A61K36/22
摘要： An anti-cancer compound is purified from Chios mastic gum resin by suspending mastic gum resin in a non-acidic, aliphatic hydrocarbon, an aqueous solution containing at least 25 percent water-soluble, non-acidic, aliphatic hydrocarbon, or a mixture or combination thereof, and removing the insoluble fraction. A method for treating cancer cells comprises administering a pharmaceutically effective amount of a fraction of mastic gum resin that inhibits growth of cancer cells. The anti-cancer compound is effective against various types of cancer cells, including human colon cancer cells.
摘要翻译：通过将乳香胶树脂悬浮在非酸性脂族烃，含有至少25％水溶性，非酸性脂族烃或其混合物或组合的水溶液中，从Chios树脂胶树脂中纯化抗癌化合物并除去不溶性部分。一种治疗癌细胞的方法包括施用药物有效量的抑制癌细胞生长的乳香胶树脂。抗癌化合物对各种癌细胞（包括人结肠癌细胞）有效。

78. 发明申请

WO2004062566A3 POLYHERBAL PREPARATION FOR THE PREVENTION OF ATHEROSCLEROSIS AND HYPERLIPIDEMIA 审中-公开
标题翻译：用于预防甲状腺功能亢进和高胆固醇的聚合物制剂
公开(公告)号：WO2004062566A3
公开(公告)日：2005-10-06
申请号：PCT/IN0300399
申请日：2003-12-26
申请人： DEPT OF BIOTECHNOLOGY INDIA , BANARAS HINDU UNIVERSITY , TRIPATHI YAMINI BHUSHAN
发明人： TRIPATHI YAMINI BHUSHAN
IPC分类号： A61K20060101 , A61K6/00 , A61K36/185 , A61K36/22 , A61K36/324 , A61K36/328 , A61K36/56 , A61K36/734 , A61K35/78
CPC分类号： A61K36/328 , A61K36/185 , A61K36/22 , A61K36/324 , A61K36/56 , A61K36/734 , Y10S514/824 , A61K2300/00
摘要： A polyherbal preparation for the prevention of atherosclerosis and hyperlipidemia comprising a mixture of Commiphora mukul, Boswellia serrata, Semecarpus anacardium Strychnos nux vomica, Termenalia arjuna and Shankha Bhusma.
摘要翻译：一种用于预防动脉粥样硬化和高脂血症的多面体制剂，其包含Comm of ul ul ata ata ata，，，，，，ica，，。。。。。。。。。。。。。。。。。。。

79. 发明申请

WO2023286977A1 수용화 매스틱 검 또는 감태나무 추출물을 이용한 항알러지용 조성물 审中-公开
公开(公告)号：WO2023286977A1
公开(公告)日：2023-01-19
申请号：PCT/KR2022/004899
申请日：2022-04-05
申请人： 주식회사 프롬바이오
发明人： 심태진 , 김지훈 , 홍인기 , 김종필 , 이유진 , 이경민 , 정정일 , 김문정
IPC分类号： A61K36/22 , A61K31/715 , A61K36/54 , A61P37/08 , A23L33/105 , A23L33/125 , A61K8/9789 , A61K8/73 , A61Q19/00
摘要： 본 발명은 IgE 및 항원(DNP-BSA)으로 활성화된 비만세포주 RBL-2H3(rat basophilic leukemia)에 처리될 때 탈과립의 억제 활성을 가지는 수용화 매스틱 검 또는 감태나무 추출물을 이용한 항알러지용 조성물을 개시한다.

80. 发明申请

WO2022250027A1 家畜の腸管細胞の炎症抑制剤审中-公开
公开(公告)号：WO2022250027A1
公开(公告)日：2022-12-01
申请号：PCT/JP2022/021171
申请日：2022-05-24
申请人：株式会社エス・ディー・エス　バイオテック , 国立大学法人東北大学
发明人：冷牟田　修一 , 小川　遼 , 犬童　優樹 , 北澤　春樹
IPC分类号： A61K36/22 , A23K10/37 , A23K50/10 , A23K50/30 , A23K50/75 , A61K31/05 , A61K31/122 , A61K31/60 , A61P1/00 , A61P29/00 , A61P43/00
摘要：カシューナッツ殻油、加熱処理カシューナッツ殻油、アナカルド酸、カルダノールおよび／またはカルドール並びにビタミンＫを含有することを特徴とする、非ヒト動物の腸管細胞の炎症抑制剤。

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