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71. 发明申请

WO2005074950A1 VERWENDUNG VON STUTENMILCH ZUR HERSTELLUNG EINES PRÄPARATS ZUR VERBESSERUNG DER SPERMIENQUALITÄT 审中-公开
标题翻译：马乳用于生产制剂用于改善精子的质量，请使用
公开(公告)号：WO2005074950A1
公开(公告)日：2005-08-18
申请号：PCT/AT2005/000038
申请日：2005-02-04
申请人： NUTROPIA ERNÄHRUNGSMEDIZINISCHE FORSCHUNGS GMBH , JUNGWIRTH, Andreas , MARKOLIN, Gertrude , FUCHS, Norbert , KÖSSLER, Peter
发明人： JUNGWIRTH, Andreas , MARKOLIN, Gertrude , FUCHS, Norbert , KÖSSLER, Peter
IPC分类号： A61K35/20
CPC分类号： A61K35/20 , A61K2300/00
摘要： Es wird eine Verwendung von Stutenmilch zur Herstellung eines Präparats zur Behandlung von Unfruchtbarkeit zur Verfügung gestellt.
摘要翻译：提供了一种用于治疗不孕不育提供的制剂的制造使用的母马乳。

72. 发明申请

WO2005041992A3 COLOSTRUM COMPOSITIONS AND METHODS 审中-公开
公开(公告)号：WO2005041992A3
公开(公告)日：2005-05-12
申请号：PCT/US2004/034770
申请日：2004-10-20
申请人： LENEAU, Harry , LENEAU, Judith , ALLDAY, Steven
发明人： LENEAU, Harry , LENEAU, Judith , ALLDAY, Steven
IPC分类号： A61K35/20
摘要： Colostrum products and a methods of using the colostrum products are provided. Methods are provided for preparing the colostrum products, which may be filtered and sterilized. The colostrum products may be injected, illustratively subcutaneously and intravenously, to provide an animal protection from disease.

73. 发明申请

WO2004075988A3 METHODS OF IMMUNOMODULATION IN ANIMALS 审中-公开
标题翻译：动物免疫调节方法
公开(公告)号：WO2004075988A3
公开(公告)日：2005-04-28
申请号：PCT/US2004005499
申请日：2004-02-25
申请人： LAURIDSON GROUP INC , CAMPBELL JOY M , STROHBEHN RONALD E , WEAVER ERIC M , BORG BARTON S , RUSSELL LOUIS E , POLO POZO FRANCISCO JAVIER , ARTHINGTON JOHN D , QUIGLEY JAMES D III
发明人： CAMPBELL JOY M , STROHBEHN RONALD E , WEAVER ERIC M , BORG BARTON S , RUSSELL LOUIS E , POLO POZO FRANCISCO JAVIER , ARTHINGTON JOHN D , QUIGLEY JAMES D III
IPC分类号： A61K35/12 , A61K35/14 , A61K35/16 , A61K35/20 , A61K39/12 , A61K39/15 , A61K39/39 , A61K39/395 , A61K39/40 , A61P20060101 , A61P11/00 , A61P37/00 , C07K1/00 , C07K14/00 , C07K16/00 , C07K16/02 , C07K16/04 , C07K16/06 , C07K17/00 , C12N1/21
CPC分类号： A61K39/15 , A23K10/00 , A61K35/16 , A61K39/12 , A61K39/39 , A61K2039/505 , A61K2039/542 , A61K2039/552 , C07K16/02 , C07K16/04 , C07K16/06 , C07K16/065 , C12N2720/12334 , C12N2770/10011 , C12N2770/10034
摘要： Methods and compositions are disclosed for the dietary modulation of the immune system and gut microbial response in animals. Applicant has identified that oral administration of a supplemental spray dried plasma purified from animal serum can modulate serum IgG levels for treatment in such things as diminished immune capacity, intestinal microbial balance, autoimmune disorders, potentiation of vaccination protocols, and improvement of overall health and weight gain in animals, including humans.
摘要翻译：公开了用于免疫系统的饮食调节和动物肠内微生物反应的方法和组合物。申请人已经确定，从动物血清中纯化的补充喷雾干燥血浆的口服给药可以调节血清IgG水平以进行治疗，例如免疫能力降低，肠微生物平衡，自身免疫疾病，增强疫苗接种方案以及提高整体健康和体重在动物，包括人类的增益。

74. 发明申请

WO2005002602A3 COMPOSITION FOR TREATING AND/OR PREVENTING DYSFUNCTIONS ASSOCIATED WITH TYPE 2 DIABETES MELLITUS AND INSULIN RESISTANCE 审中-公开
标题翻译：用于治疗和/或预防与2型糖尿病和胰岛素抵抗相关的功能障碍的组合物
公开(公告)号：WO2005002602A3
公开(公告)日：2005-04-14
申请号：PCT/EP2004007099
申请日：2004-06-30
申请人： NESTEC SA , POUTEAU ETIENNE , GARCIA-RODENAS CLARA LUCIA , MACE CATHERINE
发明人： POUTEAU ETIENNE , GARCIA-RODENAS CLARA LUCIA , MACE CATHERINE
IPC分类号： A23L1/0524 , A23L1/0526 , A23L1/053 , A23L1/305 , A23L1/308 , A61K31/195 , A61K31/198 , A61K31/732 , A61K31/736 , A61K35/20 , A61K36/00 , A61P3/06 , A61P3/10 , A61P5/50 , A61K35/78
CPC分类号： A61K35/20 , A61K38/16 , A61K38/1709 , A61K2300/00
摘要： The present invention relates to the use of a composition for treating, preventing and/or improving metabolic dysfunctions associated with type 2 diabetes mellitus and insulin resistance, said composition comprising acetogenic fibers, and at least one compound selected from the group consisting of intact whey proteins and mixtures of free amino acids, and to nutritional or pharmaceutical compositions and functional food products.
摘要翻译：本发明涉及用于治疗，预防和/或改善与2型糖尿病和胰岛素抵抗相关的代谢功能障碍的组合物的用途，所述组合物包含产乙酸纤维，和至少一种选自完整乳清蛋白的化合物和游离氨基酸的混合物，以及营养或药物组合物和功能性食品。

75. 发明申请

WO2004089278A3 SEXUAL HYGIENIC COMPOSITION 审中-公开
标题翻译：性生殖组合物
公开(公告)号：WO2004089278A3
公开(公告)日：2005-02-17
申请号：PCT/HU2004000033
申请日：2004-04-08
申请人： DOLHAY BALAZS
发明人： DOLHAY BALAZS
IPC分类号： A61K20060101 , A61K35/20 , A61K38/40 , A61P7/00 , A61P7/02 , A61P7/08 , A61P15/02 , A61K7/48
CPC分类号： A61K35/20 , A61K8/986 , A61K9/0007 , A61K9/0034 , A61K35/747 , A61Q19/10 , A61K2300/00
摘要： The invention is a sexual hygienic preparation comprising extract prepared from the milk of at least one equid animal. The preparation may contain medically/therapeutically acceptable additive(s) in specified cases. The preparation is formulated preferably as a feminine cleansing gel, feminine cleansing shampoo, feminine cleansing soap, vaginal suppository, vaginal pill, vaginal cleansing liquid, concentrate, water-soluble solid vaginal cleansing preparation, effervescent tablet, granulate, powder, lyophylized Lactobacillus preparation, spermicide preparation; adsorbent material such as dry or wet wipe, sanitary pad, vaginal suppository, containing sexual hygienic preparation.
摘要翻译：本发明是一种包括由至少一只等距动物的乳制备的提取物的性卫生制剂。在具体情况下，该制剂可含有医学/治疗上可接受的添加剂。该制剂优选配制为女性清洁凝胶，女性清洁洗发剂，女性清洁皂，阴道栓剂，阴道丸，阴道清洁液，浓缩物，水溶性固体阴道清洁制剂，泡腾片剂，颗粒剂，粉末，冻干乳酸杆菌制剂，杀精剂制剂; 吸湿材料如干湿擦拭，卫生垫，阴道栓剂，含有性卫生制剂。

76. 发明申请

WO2005002602A2 COMPOSITION FOR TREATING AND/OR PREVENTING DYSFUNCTIONS ASSOCIATED WITH TYPE 2 DIABETES MELLITUS AND INSULIN RESISTANCE 审中-公开
标题翻译：用于治疗和/或预防与2型糖尿病和胰岛素抵抗相关的功能障碍的组合物
公开(公告)号：WO2005002602A2
公开(公告)日：2005-01-13
申请号：PCT/EP2004/007099
申请日：2004-06-30
申请人： NESTEC S.A. , POUTEAU, Etienne , GARCIA-RODENAS, Clara, Lucia , MACE, Catherine
发明人： POUTEAU, Etienne , GARCIA-RODENAS, Clara, Lucia , MACE, Catherine
IPC分类号： A61K35/20
CPC分类号： A61K35/20 , A61K38/16 , A61K38/1709 , A61K2300/00
摘要： The present invention relates to the use of a composition for treating, preventing and/or improving metabolic dysfunctions associated with type 2 diabetes mellitus and insulin resistance, said composition comprising acetogenic fibers, and at least one compound selected from the group consisting of intact whey proteins and mixtures of free amino acids, and to nutritional or pharmaceutical compositions and functional food products.
摘要翻译：本发明涉及组合物用于治疗，预防和/或改善与2型糖尿病和胰岛素抵抗有关的代谢功能障碍，所述组合物包含产乙酸纤维和至少一种选择的化合物来自由完整乳清蛋白和游离氨基酸混合物组成的组，以及营养或药物组合物和功能性食品。

77. 发明申请

WO2004037851A3 COLOSTRININ AND PEPTIDES THEREOF AS MODULATORS OF INTRACELLULAR SIGNALING MOLECULES AND INHIBITORS OF APOPTOSIS 审中-公开
标题翻译：作为细胞内信号分子和抑制剂抑制剂的调节剂的胶原蛋白及其肽
公开(公告)号：WO2004037851A3
公开(公告)日：2004-12-09
申请号：PCT/US0333423
申请日：2003-10-22
申请人： UNIV TEXAS , BOLDOGH ISTVAN , STANTON JOHN G , GEORGIADES JERZY A , HUGHES THOMAS K JR , KRUZEL MARIAN
发明人： BOLDOGH ISTVAN , STANTON JOHN G , GEORGIADES JERZY A , HUGHES THOMAS K JR , KRUZEL MARIAN
IPC分类号： A61K35/20 , A61K38/08 , A61K38/10 , A61K38/17 , C07K14/47 , C07K1/14 , C07K7/06
CPC分类号： H04B1/0003 , A61K38/1709
摘要： The present invention provides methods that utilize compositions containing colostrinin, a constituent peptide thereof, an active analog thereof, and combination thereof, as modulators of intracellular signaling molecules and inhibitors of apoptosis, for example.
摘要翻译：本发明提供了使用含有colostrinin，其组成肽，其活性类似物及其组合的组合物作为细胞内信号传导分子和凋亡抑制剂的调节剂的方法。

78. 发明申请

WO02056833A3 PREPARATION OF A THERAPEUTIC COMPOSITION 审中-公开
标题翻译：治疗组合物的制备
公开(公告)号：WO02056833A3
公开(公告)日：2004-01-15
申请号：PCT/US0201496
申请日：2002-01-17
申请人： ADVANCED VIRAL RES CORP
发明人： FRIEDLAND BERNARD , HIRSCHMAN SHALOM Z , TARAPOREWALA IRACH B
IPC分类号： A61K38/01 , A61K38/17 , A61K47/48 , A61K35/20 , A61K31/7052 , A61K38/04 , A61K38/16
CPC分类号： A61K38/1709 , A61K38/00 , A61K38/385 , A61K47/64 , C07K14/47 , C07K14/4732 , C07K19/00 , A61K2300/00
摘要： Product R, a novel therapeutic composition for treating viral infections and stimulating the immune system, comprises a unique peptide having 31 amino acids and another unique peptide having 21 amino acids and connected with an oligo-nucleotide through a diphosphodiester or diphosphodithioate ester linkage. The composition has a light absorption spectrum with typical absorption ratios of 1.998 at 260nm/280nm and 1.359 at 260nm/230nm.
摘要翻译：产品R，一种用于治疗病毒感染和刺激免疫系统的新型治疗组合物，包含具有31个氨基酸的独特肽和另外具有21个氨基酸的独特肽，并通过二磷酸二酯或二磷酸二酯酸酯键与寡核苷酸连接。该组合物具有吸光光谱，在260nm / 280nm处的典型吸收比为1.998，在260nm / 230nm处为1.359。

79. 发明申请

WO2003080082A1 COMPOSITIONS CONTAINING LABILE BIOACTIVE MATERIALS AND MAMMALIAN COLOSTRUM, METHODS OF PREPARATION AND TREATMENT 审中-公开
标题翻译：含有可溶性生物材料和MAMMALIAN COLOSTRUM的组合物，制备和处理方法
公开(公告)号：WO2003080082A1
公开(公告)日：2003-10-02
申请号：PCT/AU2003/000348
申请日：2003-03-21
申请人： ANADIS LTD , RAWLIN, Grant, Thomas , LICHTI, Gottfried , ROBINS-BROWNE, Roy, Michael
发明人： RAWLIN, Grant, Thomas , LICHTI, Gottfried , ROBINS-BROWNE, Roy, Michael
IPC分类号： A61K35/20
CPC分类号： A61K35/745 , A61K35/20 , A61K35/747 , A61K45/06 , A61K47/46 , A61K2300/00
摘要： The invention relates to a method of improving the viability of a labile bioactive substance on administration to a hostile environment, the method comprising forming a mixture of the bioactive substance and mammalian colostrum and also a composition for administration of a labile bioactive substance the composition comprising a mixture of the bioactive substance and mammalian colostrum.
摘要翻译：本发明涉及一种改善不利生物活性物质施用于敌对环境的可行性的方法，所述方法包括形成生物活性物质和哺乳动物初乳的混合物，以及用于施用不稳定生物活性物质的组合物，该组合物包含生物活性物质和哺乳动物初乳的混合物。

80. 发明申请

WO03043517A3 DENTIFRICE COMPOSITIONS 审中-公开
标题翻译：牙膏组合物
公开(公告)号：WO03043517A3
公开(公告)日：2003-09-18
申请号：PCT/US0236659
申请日：2002-11-14
申请人： DANA FREDERIC , SWEETFRICE U S A INC
发明人： DANA FREDERIC
IPC分类号： A61C20060101 , A61K8/98 , A61K9/08 , A61K35/20 , A61Q11/00 , A61K7/26
CPC分类号： A61Q11/00 , A61K8/986
摘要： The present invention relates to oral care compositions which provide a means to deliver actives which are useful in the prevention, treatment and/or management of dental and related tissue conditions, including dental caries, dental cavities, microbial flora, tartar, periodontal and related gum disease. In addition, the present invention may be used in the healthy maintenance of teeth and gums. Further aspects of the present invention are related to the present compositions being useful to whiten teeth and otherwise favorably impact the cosmetic appeal of the teeth and gums of a subject or patient. A further aspect of the present invention is directed to the inclusion of effective amounts of colostrum in dental care compositions for the unexpectedly high efficacy such formulations provide in inhibiting, reducing or otherwise preventing microbial growth, dental caries, plaque, cavities and gum disease, including periodontal disease. The use of colustrum with other enzymes as otherwise described herein represents a particularly preferred embodiment for use in the present invention because of the unexpected antimicrobial activity exhibited by the enzyme combination.
摘要翻译：口腔护理组合物本发明涉及口腔护理组合物，其提供递送活性物质的手段，所述活性物质可用于预防，治疗和/或管理牙齿和相关组织状况，包括龋齿，牙腔，微生物菌群，牙垢，牙周和相关牙龈疾病。另外，本发明可用于牙齿和牙龈的健康维护。本发明的其它方面涉及本发明的组合物可用于美白牙齿并且另外有利地影响受试者或患者的牙齿和牙龈的美容吸引力。本发明的另一方面涉及在牙齿护理组合物中包含有效量的初乳以获得意想不到的高效力，所述制剂提供了抑制，减少或以其他方式预防微生物生长，龋齿，牙菌斑，牙洞和牙龈疾病，包括牙周疾病。如本文另外描述的，与其他酶一起使用生长激素代表用于本发明的特别优选的实施方案，因为酶组合显示出乎意料的抗微生物活性。

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