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61. 发明申请

WO1998028286A2 UNSATURATED (METH)ACRYLATE ESTERS CONTAINING EPOXIDIZED CYCLIC GROUPS AND PROCESS FOR PREPARING 审中-公开
标题翻译：含有环氧化环状团的不饱和（METH）丙烯酸酯和制备方法
公开(公告)号：WO1998028286A2
公开(公告)日：1998-07-02
申请号：PCT/EP1997007286
申请日：1997-12-22
申请人： SARTOMER COMPANY, INC. , CRAY VALLEY S.A. , CESKA, Gary, W. , FAN, Mingxin , HORGAN, James
发明人： SARTOMER COMPANY, INC. , CRAY VALLEY S.A.
IPC分类号： C07D303/00
CPC分类号： C07D303/40 , C07D301/12 , C07D303/16 , C07D303/24 , C08G59/24
摘要： A process of making compounds of formula (I), wherein Z is an unsubstituted or substituted n-valent cyclic moiety bearing at least one endocyclic oxirane group; Y is O, S, NH, (Ia) or (Ib); R is a divalent linking group; X is O, S or NH; R is H or (C1-C6) alkyl; and n is an integer from 1 to 6, Z being mono- to hexavalent respectively, it being possible for -Y-R to represent a single bond, comprises reacting a compound of formula (II), wherein Z is a cyclic moiety bearing at least one endocyclic C=C group; and Y, R , X, R and n are as defined above with hydrogen peroxide in the presence of (a) tungstic acid or tungsten oxide or molybdic acid or a molybdenum oxide; (b) phosphoric acid or a salt thereof; and (c) at least one phase transfer catalyst.
摘要翻译：制备式（I）化合物的方法，其中Z是具有至少一个环内环氧基团的未取代或取代的n价环状部分; Y是O，S，NH，（Ia）或（Ib）; R 2是二价连接基团; X是O，S或NH; R 1是H或（C 1 -C 6）烷基; n为1〜6的整数，Z分别为1〜6价，-YR 2可以表示单键，包括使式（II）化合物（其中Z 1为具有至少一个环内C = C基团的环状部分; 在（a）钨酸或钨氧化物或钼酸或氧化钼的存在下，Y，R 2，X，R 1和n如上定义，与过氧化氢反应; （b）磷酸或其盐; 和（c）至少一种相转移催化剂。

62. 发明申请

WO1996026199A1 ACTIVE BIO-COMPOUNDS 审中-公开
标题翻译：活性生物化合物
公开(公告)号：WO1996026199A1
公开(公告)日：1996-08-29
申请号：PCT/DK1996000081
申请日：1996-02-23
申请人： NOVO NORDISK A/S , BREINHOLT, Jens
发明人： NOVO NORDISK A/S
IPC分类号： C07D303/12
CPC分类号： C07D303/38 , A01N43/20 , A01N63/04 , C07D303/40 , C12P29/00 , C12R1/645
摘要： The invention relates to biologically active novel compounds having general formula (I), wherein R2 and R13 are hydrogen, straight or branched chain alkyl, straight or branched chain alkenyl, straight or branched chain alkynyl, benzyl or aryl, optionally mono- or plurisubstituted with alkyl, atoms, hydroxy, alkoxy, halogen, amino or a nitro group; and R8 is hydrogen, -COR, straight or branched chain alkyl, straight or branched chain alkenyl, straight or branched chain alkynyl, benzyl or aryl; R1, R2, R3, R4, R5, R6, R7, R9, R10, R11, and R12 are hydrogen or together with an adjacent R-group represent an additional bond; and R is a straight or branched chain alkyl, straight or branched chain alkenyl, straight or branched chain alkynyl, aryl. A method of preparing said compounds, fungicidal compositions comprising, as an active ingredient, these compounds, use of the compounds and an isolated pure culture of the microorganism Hamigera avellanea NN005492 (CBS No. 501.94) or a mutant thereof.
摘要翻译：本发明涉及具有通式（I）的生物活性新型化合物，其中R 2和R 13是氢，直链或支链烷基，直链或支链烯基，直链或支链炔基，苄基或芳基，任选被单取代或被烷基，原子，羟基，烷氧基，卤素，氨基或硝基; R 8为氢，-COR，直链或支链烷基，直链或支链烯基，直链或支链炔基，苄基或芳基; R 1，R 2，R 3，R 4，R 5，R 6，R 7，R 9，R 10，R 11和R 12是氢或与相邻的R基团一起代表另外的键; R是直链或支链烷基，直链或支链烯基，直链或支链炔基，芳基。一种制备所述化合物的方法，所述杀真菌组合物包含这些化合物作为活性成分，所述化合物的使用和分离的微生物Hamigera avellanea NN005492（CBS No.51.94）的纯培养物或其突变体。

63. 发明申请

WO1991015473A1 LEUCOTRIENE ANTAGONISTS, A PREPARATION METHOD THEREFOR AND THERAPEUTIC USES THEREOF 审中-公开
标题翻译：低分子拮抗剂，其制备方法及其治疗方法
公开(公告)号：WO1991015473A1
公开(公告)日：1991-10-17
申请号：PCT/FR1991000268
申请日：1991-04-03
申请人： LABORATOIRES FOURNIER S.C.A. , LABORATOIRE CHAUVIN , BENAISSA, Boubia , MIOSKOWSKI, Charles , BELLAMY, François
发明人： LABORATOIRES FOURNIER S.C.A. , LABORATOIRE CHAUVIN
IPC分类号： C07C323/54
CPC分类号： C07D303/22 , C07C323/54 , C07C323/56 , C07D303/40 , C07D307/33 , C07D309/30 , C07D319/12
摘要： A novel industrial product in the form of compounds which are particularly useful as leucotriene antagonists, said compounds being selected from the group which comprises the products of formulas (I) and (Ia), wherein Y represents a -(CH2)2-CH3 group or a phenyl group; the symbol (α) represents a cis (Z) or trans (E) double bond; X represents a -(CH2)2- group, a -(CH2)3- group or a -CH2OCH2- group; R represents a hydrogen atom, a C1-4 alkyl group or an alkali metal atom; R' represents a C1-4 alkyl group; and the enantiomers and diastereoisomers of said products.

64. 发明申请

WO1991005766A1 2-SUBSTITUTED 2-CYCLOPENTENONE AND CARCINOSTATIC AGENT AND OSTEOGENESIS PROMOTER CONTAINING THE SAME AS ACTIVE INGREDIENT 审中-公开
标题翻译： 2-取代的2-环烯酸和含有相同活性成分的致癌物质和促蛋白酶
公开(公告)号：WO1991005766A1
公开(公告)日：1991-05-02
申请号：PCT/JP1990001343
申请日：1990-10-18
申请人： TEIJIN LIMITED , SUGIURA, Satoshi , MINOSHIMA, Toru , HAZATO, Atsuo , KATO, Yoshinori
发明人： TEIJIN LIMITED
IPC分类号： C07C317/24
CPC分类号： C07D213/70 , C07C45/72 , C07C49/707 , C07C49/753 , C07C317/24 , C07C317/46 , C07C323/22 , C07C323/61 , C07C405/0033 , C07C2601/10 , C07C2601/14 , C07D233/84 , C07D239/38 , C07D257/04 , C07D263/58 , C07D277/16 , C07D277/74 , C07D303/40 , C07D307/38 , C07D307/46 , C07D405/12 , C07D473/38 , C07F7/1804 , C07H13/04
摘要： A 2-substituted 2-cyclopentenone of formula (I) and a carcinostatic agent and an osteogenesis promoter containing the same as the active ingredient.
摘要翻译：式（I）的2-取代的2-环戊烯酮和含有与活性成分相同的制癌剂和成骨促进剂。

65. 发明申请

WO1987004515A1 ELECTRONIC INCLINOMETER 审中-公开
标题翻译：电子内置仪
公开(公告)号：WO1987004515A1
公开(公告)日：1987-07-30
申请号：PCT/GB1987000042
申请日：1987-01-23
申请人： DURACELL INTERNATIONAL INC. , RYAN, Paul, Thomas , WISEMAN, Colin, Phillip , WYATT-MILLINGTON, Charles, William
发明人： DURACELL INTERNATIONAL INC.
IPC分类号： G01C09/20
CPC分类号： C07C33/30 , C07C59/48 , C07C323/00 , C07D213/30 , C07D213/55 , C07D303/40 , C07D307/42 , C07D307/54 , C07D309/30 , C07D405/06 , C07K5/0606 , G01C9/06 , G01C9/20
摘要： A sensor for an inclination measuring device which comprises a capsule (3) part-filled with a conductive liquid. First to fourth electrodes (A-D) are disposed within the capsule in contact with the liquid. An electrical signal is applied between electrodes (C, D) and one then the other of electrodes (A, B), to derive a signal indicative of the degree of immersion of the electrode (A), and then the electrode (B) within the liquid. The ratio of these signals is related to the angle of inclination of the capsule about the reference axis O and relative to a first reference angle defined at the gap between the electrodes (A, B). A similar gap, defining a second reference angle is disposed between electrodes (C, D), perpendicular to the gap between electrodes (A, B), and by reconfiguring the electrodes (A-D), to measure the degree of immersion of electrodes (C and D), the sensor is able to sense any angle of inclination about the reference axis.
摘要翻译：一种用于倾斜测量装置的传感器，其包括部分填充有导电液体的胶囊（3）。第一至第四电极（A-D）设置在与液体接触的胶囊内。在电极（C，D）和电极（A，B）之间施加电信号以导出指示电极（A）的浸入程度的信号，然后将电极（B）液体。这些信号的比例与胶囊围绕参考轴线O的倾斜角度和相对于在电极（A，B）之间的间隙处限定的第一参考角度相关。在与电极（A，B）之间的间隙垂直的电极（C，D）之间并且通过重新配置电极（AD），限定第二参考角的类似间隙，以测量电极（C 和D），传感器能够感测围绕参考轴线的任何倾斜角度。

66. 发明申请

WO2018069458A1 PROCESS FOR THE MANUFACTURE OF 6-METHOXY-2,6-DIMETHYLHEPTANAL 审中-公开
标题翻译：制备6-甲氧基-2,6-二甲基庚烷的方法
公开(公告)号：WO2018069458A1
公开(公告)日：2018-04-19
申请号：PCT/EP2017/076089
申请日：2017-10-12
申请人： DSM IP ASSETS B.V.
发明人： BEUMER, Raphael , BONRATH, Werner , FISCHESSER, Jocelyn
IPC分类号： C07C45/58 , C07C45/64 , C07D301/02 , C07C49/175 , C07C47/198
CPC分类号： C07C45/64 , C07C45/58 , C07D301/02 , C07D303/38 , C07D303/40 , C07C49/175 , C07C47/198
摘要： The present invention relates to an improved process for the manufacture of 6-methoxy-2,6-dimethylheptanal.
摘要翻译：本发明涉及制备6-甲氧基-2,6-二甲基庚醛的改进方法。

67. 发明申请

WO2015067814A2 "PLASTICIZERS FOR POLYMERS" 审中-公开
标题翻译： “用于聚合物的增塑剂”
公开(公告)号：WO2015067814A2
公开(公告)日：2015-05-14
申请号：PCT/EP2014/074208
申请日：2014-11-10
申请人： FLUOS S.A.S. DI GIUSEPPE CHIARADIA & C.
发明人： CHIARADIA, Giuseppe
IPC分类号： C08K5/00
CPC分类号： C08K5/1515 , C07D303/40 , C07D407/12 , C08K5/0016 , C08K5/10 , C08K5/1565
摘要： The present invention refers to plasticizers derived from vegetable oils for thermoplastic polymers and resins, in particular, plasticizers for Polyvinylchloride (PVC). Furthermore, the invention relates to a method for preparing such plasticizers. Plasticizers comprise esters of carboxyl fatty acids wherein fatty acids are selected from those having a hydrocarbon chain comprised between C 12 e C 22 , wherein the double bonds of the hydrocarbon chain of the carboxylic fatty acid are epoxidized, and the esterification is with a cyclic acetal or ketal.
摘要翻译：本发明涉及用于热塑性聚合物和树脂的植物油衍生的增塑剂，特别是用于聚氯乙烯（PVC）的增塑剂。此外，本发明涉及制备这种增塑剂的方法。增塑剂包含羧基脂肪酸的酯，其中脂肪酸选自具有包含在C12C22C22之间的烃链的那些，其中脂肪酸的烃链的双键羧酸脂肪酸被环氧化，并且酯化是用环状缩醛或缩酮。

68. 发明申请

WO2015052156A1 PROCESS FOR PREPARING 4-[[(BENZOYL)AMINO]SULPHONYL]BENZOYL CHLORIDES AND PREPARATION OF ACYLSULPHAMOYLBENZAMIDES 审中-公开
标题翻译：制备4 - [[（苯甲酰基）氨基]磺酰基]苯甲酰氯的方法和氰尿酸苯甲酸酯的制备
公开(公告)号：WO2015052156A1
公开(公告)日：2015-04-16
申请号：PCT/EP2014/071388
申请日：2014-10-07
申请人： BAYER CROPSCIENCE AG
发明人： FARIDA, Taraneh , STAKEMEIER, Hubertus , VERMEHREN, Jan
IPC分类号： C07D303/40
CPC分类号： C07C303/40 , C07C303/36 , C07C311/16 , C07D303/40
摘要： Process for preparing 4-[[(benzoyl)amino]sulphonyl]benzoyl chlorides and for preparing acylsulphamoylbenzamides Process for preparing 4-[[(benzoyl)amino]sulphonyl]benzoyl chlorides of the fornnula (II), proceeding from ortho-methoxybenzoic acid compounds of the formula (III) and 4- sulphamoylbenzoic acid compounds of the formula (IV), and processes for preparing the compound (lb), used in agriculture as a safener, cyprosulphamide (A/-[4-(cyclopropylcarbamoyl)phenylsulphonyl]-2- methoxybenzamide).
摘要翻译：制备4 - [[（苯甲酰基）氨基]磺酰基]苯甲酰氯并用于制备酰基氨磺酰苯甲酰胺的方法由邻 - 甲氧基苯甲酸化合物制备4 - [[（苯甲酰基）氨基]磺酰基]苯甲酰氯的方法（III）的4-氨磺酰基苯甲酸化合物和用于农业中安全剂的化合物（Ib）的方法，环丙磺酰胺（A / [4-（环丙基氨基甲酰基）苯基磺酰基] - 2-甲氧基苯甲酰胺）。

69. 发明申请

WO2012041816A1 DERIVATIVE OF EPICHLOROHYDRIN OF NATURAL ORIGIN 审中-公开
标题翻译：天然原生动物的衍生物
公开(公告)号：WO2012041816A1
公开(公告)日：2012-04-05
申请号：PCT/EP2011/066689
申请日：2011-09-26
申请人： SOLVAY SA , GILBEAU, Patrick
发明人： GILBEAU, Patrick
IPC分类号： C07D301/26 , C07D303/08 , C07D303/16 , C07D303/18 , C07D303/40 , C07D303/46
CPC分类号： C07D303/08 , C07D301/26 , C07D303/16 , C07D303/18 , C07D303/40 , C07D303/46
摘要： Derivative of epichlorohydrin of natural origin, selected from the group consisting of glycidyl ethers presenting an epoxide equivalent weight higher than or equal to 50 g/equivalent and lower than or equal to 15000 g/equivalent, of glycidyl esters, of glycidyl amides, of glycidyl imides, of glycidyl amines, and of any mixture thereof, and of which the 14 C mass content is such that the ratio 14 C / 12 C is higher than 0.7 10 -12 .
摘要翻译：天然来源的表氯醇的衍生物，其选自环氧当量高于或等于50g /当量且低于或等于15000g /当量的缩水甘油酯，缩水甘油基酰胺，缩水甘油基酰亚胺，缩水甘油胺及其任何混合物，其14C质量含量使得14C / 12C比高于0.7×10-12。

70. 发明申请

WO2012010555A1 TRICYCLIC LACTONES FOR TREATMENT OF CANCER 审中-公开
标题翻译：治疗癌症的治疗手段
公开(公告)号：WO2012010555A1
公开(公告)日：2012-01-26
申请号：PCT/EP2011/062243
申请日：2011-07-18
申请人： PARTNERS FÖR UTVECKLINGSINVESTERINGAR INOM LIFE SCIENCES, P.U.L.S. AB , GIDLÖF, Ritha , JOHANSSON, Martin , STERNER, Olov , MUÑOZ, Eduardo
发明人： GIDLÖF, Ritha , JOHANSSON, Martin , STERNER, Olov , MUÑOZ, Eduardo
IPC分类号： C07D303/38 , C07D307/93 , A61K31/365 , A61K31/336 , A61P35/00
CPC分类号： C07D307/93 , A61K31/336 , A61K31/365 , A61K45/06 , C07D303/38 , C07D303/40
摘要： The present invention discloses novel compounds useful for the inhibition of IL-6/STAT signaling and/or PI3K/ NF-ĸΒ signaling in the treatment of associated diseases or conditions, e.g. cancer. A pharmaceutical composition comprising such novel compounds, its use and a method thereof, is also disclosed.
摘要翻译：本发明公开了可用于抑制IL-6 / STAT信号传导和/或PI3K / NF-κB的新型化合物。用于治疗相关疾病或病症的信号，例如。癌症。还公开了包含这些新化合物的药物组合物及其用途及其方法。

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