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61. 发明申请

WO2015042445A3 APPARATUS, METHOD, AND NON-TRANSITORY MEDIUM FOR OPTICAL STABILIZATION AND DIGITAL IMAGE REGISTRATION IN SCANNING LIGHT OPHTHALMOSCOPY 审中-公开
标题翻译：用于光学稳定和数字图像配准的设备，方法和非过渡介质在扫描光学眼科中的应用
公开(公告)号：WO2015042445A3
公开(公告)日：2015-05-28
申请号：PCT/US2014056628
申请日：2014-09-19
申请人： CANON KK , UNIV ROCHESTER , SAITO KENICHI , YANG QIANG , ZHANG JIE , NOZATO KOJI
发明人： SAITO KENICHI , YANG QIANG , ZHANG JIE , NOZATO KOJI
IPC分类号： A61B3/10 , A61B3/00 , G06T7/20
CPC分类号： A61B3/1025 , A61B3/0025 , A61B3/12 , A61B3/14 , G06T7/246 , G06T2207/10016 , G06T2207/30041
摘要： Apparatus, method, and non-transitory medium for optical stabilization and digital image registration in scanning light ophthalmoscopy. Scanning an object with measurement light. Acquire an image of the object to be examined based on return light from the object. Acquire information which indicates movement of the object to be examined based on a plurality of acquired images. Control the scanning based on the information which indicates the movement of the object to be examined. Performing registration of the plurality of images.
摘要翻译：用于扫描光检眼镜中的光学稳定化和数字图像配准的设备，方法和非暂时性介质。用测量光线扫描物体。根据来自物体的返回光，获取待检查物体的图像。基于多个获取的图像获取指示待检查对象的移动的信息。基于指示待检查对象的移动的信息来控制扫描。执行多个图像的登记。

62. 发明申请

WO2012064766A3 SHEET AND LIQUID COMBINATION SYSTEMS FOR DERMAL DRUG DELIVERY 审中-公开
标题翻译：用于真菌药物递送的片剂和液体组合系统
公开(公告)号：WO2012064766A3
公开(公告)日：2014-04-17
申请号：PCT/US2011059813
申请日：2011-11-08
申请人： ZHANG JIE
发明人： ZHANG JIE
IPC分类号： A61F13/00
CPC分类号： A61F13/00063 , A61K9/7023
摘要： A dermal drug delivery system is provided which comprises at least two components, for example, a sheet of a solid and flexible material, and a vehicle liquid comprising a solvent and optionally other ingredients. A drug can be impregnated in the sheet. Other ingredients, such as agents for fastening the drug on the sheet can also be impregnated in the sheet. These two components may be stored separately and joined either shortly before or at the time of application. To use the system, the vehicle liquid may be applied either on the target skin area or on the sheet, and the sheet may then be applied on the target skin area so that the vehicle liquid is positioned between the sheet and the skin and brought into contact with the ingredients impregnated in the sheet.
摘要翻译：提供了一种真皮药物递送系统，其包括至少两种组分，例如固体和柔性材料片，以及包含溶剂和任选的其它成分的载体液体。药物可以浸渍在片材中。其他成分，例如用于将药物紧固在片材上的药剂也可以浸渍在片材中。这两个组件可以单独存储，也可以在应用之前或施用时加入。为了使用该系统，可以将车辆液体施加在目标皮肤区域或片材上，然后可以将片材施加在目标皮肤区域上，使得车辆液体位于片材和皮肤之间并进入与浸渍在片材中的成分接触。

63. 发明申请

WO2011140236A2 TRIAMCINOLONE ACETONIDE FORMULATIONS FOR TREATING DERMATITIS AND PSORIASIS 审中-公开
标题翻译：用于治疗牙龈萎缩症的三氰菊酯乙酰胆碱配方
公开(公告)号：WO2011140236A2
公开(公告)日：2011-11-10
申请号：PCT/US2011035216
申请日：2011-05-04
申请人： ZARS PHARMA INC , ALIYAR HYDER , ZHANG JIE
发明人： ALIYAR HYDER , ZHANG JIE
IPC分类号： A61K9/06 , A61K31/56 , A61K31/57 , A61K47/30 , A61K47/34 , A61P17/00
CPC分类号： A61K31/58 , A61K9/0014 , A61K31/57 , A61K47/10 , A61K47/32
摘要： The present invention is drawn to formulations and related methods for treating dermatitis or psoriasis. The formulation can include triamcinolone acetonide, a polymer selected from the group of a poly(2-hydroxyalkylacrylate), a poly(2-hydroxyalkylmethacrylate), and combinations thereof. The formulation also includes a volatile solvent system including at least one volatile solvent, and a non-volatile solvent system including at least one non-volatile solvent.
摘要翻译：本发明涉及用于治疗皮炎或牛皮癣的制剂和相关方法。制剂可以包括曲安奈德，选自聚（2-羟烷基丙烯酸酯），聚（2-羟烷基甲基丙烯酸酯）和其组合的聚合物。该制剂还包括包含至少一种挥发性溶剂的挥发性溶剂体系和包含至少一种非挥发性溶剂的非挥发性溶剂体系。

64. 发明申请

WO2011028542A3 METHODS OF TREATING PAIN ASSOCIATED WITH COMPLEX REGIONAL PAIN SYNDROME 审中-公开
标题翻译：治疗与复合性局部疼痛综合征有关的疼痛的方法
公开(公告)号：WO2011028542A3
公开(公告)日：2011-07-21
申请号：PCT/US2010046523
申请日：2010-08-24
申请人： ZARS PHARMA INC , ZHANG JIE , CROCKETT ANDREW , RIGBY LARRY
发明人： ZHANG JIE , CROCKETT ANDREW , RIGBY LARRY
IPC分类号： A61K31/245 , A61K31/165 , A61K31/167 , A61K31/24 , A61P17/00 , A61P29/00
CPC分类号： A61K45/06 , A61K31/165 , A61K31/167 , A61K31/24 , A61K31/245 , A61K2300/00
摘要： The present invention is drawn to methods for treating pain associated with complex regional pain syndrome. Specifically, a method for treating pain associated with complex regional pain syndrome includes the application of an analgesic system to a skin surface of a subject experiencing the pain and maintaining the analgesic system on the skin surface for a period of time of at least 30 minutes. The analgesic system applied to the skin surface can include a heating component and a local anesthetic formulation which includes at least one local anesthetic. The heating component can be capable of heating the skin surface to a temperature of 36°C to 42°C.
摘要翻译：本发明涉及治疗与复杂区域性疼痛综合征相关的疼痛的方法。具体而言，用于治疗与复合区域性疼痛综合征相关的疼痛的方法包括将镇痛系统应用于经历疼痛的受试者的皮肤表面并将该镇痛系统维持在皮肤表面上至少30分钟的时间段。应用于皮肤表面的止痛系统可以包括加热部件和包含至少一种局部麻醉剂的局部麻醉剂。加热部件能够将皮肤表面加热至36℃至42℃的温度。

65. 发明申请

WO2009092723A3 A COMMUNICATION METHOD FOR A RADIO SYSTEM AND APPARATUS AND SYSTEM FOR IMPLEMENTING THE METHOD 审中-公开
标题翻译：一种用于无线电系统的通信方法和用于实现该方法的装置和系统
公开(公告)号：WO2009092723A3
公开(公告)日：2009-11-05
申请号：PCT/EP2009050641
申请日：2009-01-21
申请人： SIEMENS AG , HORST DIETER , LAMPE MATTIAS , YU DAN , YUAN YONG , ZHANG JIE
发明人： HORST DIETER , LAMPE MATTIAS , YU DAN , YUAN YONG , ZHANG JIE
IPC分类号： H04B7/02
CPC分类号： H04B7/02 , H04B5/00
摘要： A communication method in which, a reflection-transmission apparatus (3) is disposed in radio system; during a communication process, said reflection-transmission apparatus's reflection and transmission feature presented to the radio frequency are changed, so as to introduce a multi-path signal component which changes with time; such that during the communication process, a receiving apparatus receives and combines the multi-path signal component of communication signals; and said radio system carries out communication by utilizing time diversity effects. The present invention is particularly suitable to a radio frequency identification system RFID (4), and by way of the method, apparatus and system of the present invention, continued communication blind spots in the system can be reduced effectively, thereby improving the overall success rate for the RFID system (4) to read tags and accomplishing a better balance with the overall reading time.
摘要翻译：一种反射传输装置（3）设置在无线电系统中的通信方法，在通信处理期间，改变呈现给射频的反射传输装置的反射和传输特征，以便引入随时间变化的多径信号分量; 使得在通信过程期间，接收装置接收并组合通信信号的多路径信号分量; 并且所述无线电系统通过利用时间分集效应来进行通信。本发明特别适用于射频识别系统RFID（4），并且通过本发明的方法，装置和系统，可以有效降低系统中持续的通信盲点，从而提高整体成功率用于RFID系统（4）读取标签并在整体阅读时间内实现更好的平衡。

66. 发明申请

WO2007070679A3 COMPOSITIONS AND METHODS FOR DERMALLY TREATING PAIN 审中-公开
标题翻译：用于牙痛治疗的组合物和方法
公开(公告)号：WO2007070679A3
公开(公告)日：2009-01-08
申请号：PCT/US2006047926
申请日：2006-12-14
申请人： ZARS INC , ZHANG JIE , WARNER KEVIN S , SHARMA SANJAY
发明人： ZHANG JIE , WARNER KEVIN S , SHARMA SANJAY
IPC分类号： A01N37/12
CPC分类号： A61K9/0014 , A61K47/10 , A61K47/18
摘要： The present invention is drawn to solidifying formulations for dermal delivery of a drug for treating pain, such as musculoskeletal pain, inflammation, joint pain, or neuropathic pain. The formulation can include a drug selected from certain drug classes, a solvent vehicle, and a solidifying agent. The solvent vehicle can include a volatile solvent system comprising at least one volatile solvent, and a non-volatile solvent system comprising at least one non-volatile solvent, wherein the evaporation of at least some of the volatile solvent converts the formulation on the skin into a solidified layer and the non-volatile solvent system is capable of facilitating the topical delivery of the drug(s) at therapeutically effective rates over a sustained period of time.
摘要翻译：本发明涉及用于皮肤递送用于治疗疼痛的药物如肌肉骨骼疼痛，炎症，关节疼痛或神经性疼痛的固化制剂。制剂可以包括选自某些药物类别的药物，溶剂载体和固化剂。溶剂载体可以包括包含至少一种挥发性溶剂的挥发性溶剂体系和包含至少一种非挥发性溶剂的非挥发性溶剂体系，其中至少一些挥发性溶剂的蒸发将皮肤上的制剂转化成固化层和非挥发性溶剂体系能够在持续的时间内以治疗有效的速率促进药物的局部递送。

67. 发明申请

WO2007070694A2 SPRAY-ON FORMULATIONS AND METHODS FOR DERMAL DELIVERY OF DRUGS 审中-公开
标题翻译：用于药物递送的喷雾配方和方法
公开(公告)号：WO2007070694A2
公开(公告)日：2007-06-21
申请号：PCT/US2006048060
申请日：2006-12-14
申请人： ZARS INC , ZHANG JIE , WARNER KEVIN S , SHARMA SANJAY
发明人： ZHANG JIE , WARNER KEVIN S , SHARMA SANJAY
IPC分类号： A61K9/12
CPC分类号： A61K9/7015 , A61K47/10 , A61K47/12 , A61K47/32 , A61K47/34
摘要： The present invention is drawn to sprayable formulations, methods of drug delivery, and resultant solidified layers for dermal delivery of a drug. The formulation can include a drug, a non-volatile solvent system, a solidifying agent, and a propellant. The formulation can have an initial viscosity suitable to be expelled out of a pressurized or manual pump container and applied onto a skin surface as a layer. When applied to the skin, the formulation can form a solidified layer after at least a portion of the propellant is evaporated.
摘要翻译：本发明涉及可喷雾制剂，药物递送方法，以及用于药物真皮递送的所得固化层。制剂可以包括药物，非挥发性溶剂体系，固化剂和推进剂。制剂可以具有适于从加压或手动泵容器中排出的初始粘度，并将其施加到作为层的皮肤表面上。当施用于皮肤时，在推进剂的至少一部分蒸发之后，制剂可以形成固化层。

68. 发明申请

WO2006053222A3 INSTANT PATCH FOR DERMAL DRUG DELIVERY 审中-公开
标题翻译：用于皮肤药物递送的即时贴剂
公开(公告)号：WO2006053222A3
公开(公告)日：2006-08-31
申请号：PCT/US2005040938
申请日：2005-11-11
申请人： ZARS INC , ZHANG JIE , WARNER KEVIN S
发明人： ZHANG JIE , WARNER KEVIN S
IPC分类号： A61F13/00 , A61F13/02
CPC分类号： A61K9/703 , A61K9/7084 , A61L15/16 , A61L15/44 , A61L15/60 , A61L2300/40 , A61L2300/602
摘要： The present invention is drawn toward systems, devices, and methods of dermal drug delivery. The system can comprise a gel-triggering agent and a drug-containing composition including a drug and a gelling agent, wherein the drug-containing composition forms a soft, coherent solid when contacted with the gell-triggering agent. A cavity patch (10) is also included having an open cavity (18) configured to be closed at least in part by a skin surface (44). The open cavity can be further configured to facilitate contact between the skin surface and the gel. The gel-triggering agent and the drug-containing composition can be positioned in the system such that they are kept isolated from one another until immediately before or during use.
摘要翻译：本发明涉及皮肤给药的系统，装置和方法。该系统可以包含凝胶触发剂和包含药物和胶凝剂的含药物组合物，其中当与凝胶触发剂接触时，含药物组合物形成柔软的粘附固体。还包括空腔补片（10），其具有构造成至少部分地由皮肤表面（44）封闭的开放空腔（18）。开放腔可以进一步配置成促进皮肤表面和凝胶之间的接触。凝胶触发剂和含有药物的组合物可以位于系统中，使得它们在使用前或使用过程中保持彼此隔离。

69. 发明申请

WO2006053223A3 SYSTEMS AND METHODS FOR TREATING WARTS 审中-公开
标题翻译：用于处理战争的系统和方法
公开(公告)号：WO2006053223A3
公开(公告)日：2006-07-27
申请号：PCT/US2005040939
申请日：2005-11-11
申请人： ZARS INC , ZHANG JIE , WARNER KEVIN S
发明人： ZHANG JIE , WARNER KEVIN S
IPC分类号： A61F13/00 , A61F13/02
CPC分类号： A61K9/703 , A61F13/063 , A61K9/7084 , A61L15/16 , A61L15/44 , A61L15/60 , A61L2300/40 , A61L2300/602
摘要： The present invention is drawn to systems and methods for treating warts. The system can comprise a wart treatment formulation comprising a substance for treating warts and a cavity patch (10) comprising an open cavity (18) being configured to become a closed cavity upon application and adherence to a skin surface (44). The closed cavity can be configured to contain the wart treatment formulation.
摘要翻译：本发明涉及用于治疗疣的系统和方法。该系统可以包括疣治疗制剂，其包括用于治疗疣的物质和包括开放腔（18）的空腔贴片（10），所述开口腔被构造成在施用并粘附到皮肤表面（44）时变成闭合腔。闭合的腔体可以构造成容纳疣治疗制剂。

70. 发明申请

WO2005049806A3 NOVEL NUCLEIC ACIDS AND POLYPEPTIDES 审中-公开
标题翻译：新型核酸和多肽
公开(公告)号：WO2005049806A3
公开(公告)日：2005-12-29
申请号：PCT/US2004007412
申请日：2004-03-11
申请人： NUVELO INC , TANG TOM Y , WANG JIAN-RUI , WANG ZHI WEI , ZHANG JIE , REN FEIYAN , ZHOU PING , MA YUNQING , GHOSH MALABIKA , XUE AIDONG , ASUNDI VINOD , ZHAO QING , WANG DUNRUI , GOODRICH RYLE , CHEN RUI-HONG , WEHRMAN TOM , WENG GEZHI , BOYLE BRYAN
发明人： TANG TOM Y , WANG JIAN-RUI , WANG ZHI WEI , ZHANG JIE , REN FEIYAN , ZHOU PING , MA YUNQING , GHOSH MALABIKA , XUE AIDONG , ASUNDI VINOD , ZHAO QING , WANG DUNRUI , GOODRICH RYLE , CHEN RUI-HONG , WEHRMAN TOM , WENG GEZHI , BOYLE BRYAN
IPC分类号： C07K14/47 , C12N20060101 , C12P19/34 , C12Q1/68 , C07H210
CPC分类号： C07K14/47
摘要： The present invention provides nucleic acids, novel polypeptide sequences encoded by these nucleic acids and uses thereof.
摘要翻译：本发明提供核酸，由这些核酸编码的新多肽序列及其用途。

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