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51. 发明申请

WO2005090383A2 PROCESS FOR PREPARING MACROCYCLIC COMPOUNDS 审中-公开
标题翻译：制备适用于治疗丙型肝炎病毒感染的大环切片剂的方法
公开(公告)号：WO2005090383A2
公开(公告)日：2005-09-29
申请号：PCT/US2005/008366
申请日：2005-03-11
申请人： BOEHRINGER INGELHEIM INTERNATIONAL, GMBH , BUSACCA, Carl, Alan , FARINA, Vittorio , GALLOU, Fabrice , HADDAD, Nizar , WANG, Xiao-jun , WEI, Xudong , XU, Jinghua , XU, Yibo , YEE, Nathan, K. , ZHANG, Li
发明人： BUSACCA, Carl, Alan , FARINA, Vittorio , GALLOU, Fabrice , HADDAD, Nizar , WANG, Xiao-jun , WEI, Xudong , XU, Jinghua , XU, Yibo , YEE, Nathan, K. , ZHANG, Li
IPC分类号： C07K5/06
CPC分类号： C07K5/0802 , A61K38/00 , C07D417/14 , C07K1/006 , C07K5/06165 , C07K5/0827
摘要： Disclosed is a multi-step process for preparing a macrocyclic compound of the formula (I); wherein Q is a radical of the following formula (II); and the other variables are as defined herein. The compounds of formula (I) are potent active agents for the treatment of hepatitis C virus (HCV) infection.
摘要翻译：公开了制备式（I）的大环化合物的多步法; 其中Q是下式（II）的基团：其他变量如本文所定义。式（I）化合物是用于治疗丙型肝炎病毒（HCV）感染的有效活性剂。

52. 发明申请

WO2005089513A2 PRODUCTION LINE AND TREATMENT FOR ORGANIC PRODUCT 审中-公开
标题翻译：生产线和有机产品处理
公开(公告)号：WO2005089513A2
公开(公告)日：2005-09-29
申请号：PCT/US2005/009312
申请日：2005-03-17
申请人： GE IONICS, INC. , ZHANG, Li , ZHENG, Yongchang , MACDONALD, Russell, J. , JU, Alex
发明人： ZHANG, Li , ZHENG, Yongchang , MACDONALD, Russell, J. , JU, Alex
IPC分类号： B01D61/44 , B01D61/46 , C12M1/00
CPC分类号： B01D61/46 , B01D61/445 , C07K1/24 , C12M47/12
摘要： A fluid from a fermentation process or the like is passed or circulated through chambers of a bipolar membrane electrodialysis unit to separate an ionizable organic acid stream and at least one co-ion or residual stream. The organic acid stream is preferably concentrated (e.g., by recirculation, dewatering or both), and a product is recovered from the concentrated stream, for example by crystallization, and other outputs from the electrodialysis unit may be integrated with overall treatment and applied elsewhere in the treatment system. Depleted feed may be returned upstream to enhance yield, condition the medium or form a by-product. Treatment systems of the invention may replace a cation exchange bed and/or various filter arrangements, and recirculation of the feed and product flows through the unit enhance recovery, separation and quality of the target species. An ED chamber may include a filling of ion exchange beads to maintain a desired operating efficiency as the feed is depleted, and the straightthrough operation effectively operates as pre-filtration stage to provide downstream product-bearing flows with processing characteristics for enhanced treatment, recovery and product quality. When operated to treat a downstream waste, systems allow additional recovery of value in the form of product, unexpended nutrients, co-factors and/or other components present in the waste.
摘要翻译：来自发酵过程等的流体通过或循环通过双极膜电渗析装置的室，以分离出可电离的有机酸流和至少一种共离子或残余流。优选浓缩有机酸流（例如通过再循环，脱水或两者），并且例如通过结晶从浓缩物流中回收产物，并且来自电渗析装置的其它输出可以与整体处理相结合并在其它地方应用治疗系统。消耗的饲料可以向上游返回以提高产量，调节培养基或形成副产物。本发明的处理系统可以替代阳离子交换床和/或各种过滤器装置，并且通过该单元的进料和产物流的再循环增强了目标物种的回收，分离和质量。 ED室可以包括填充离子交换珠，以在进料耗尽时保持期望的操作效率，并且直通操作有效地作为预过滤阶段进行运作，以提供具有加工特性的下游产品流动，用于增强处理，回收和产品质量。当操作处理下游废物时，系统允许以产品，未用的营养物，辅因子和/或废物中存在的其他成分的形式额外回收价值。

53. 发明申请

WO2020069638A1 PAGE NAVIGATION WITH TREE MENU 审中-公开
公开(公告)号：WO2020069638A1
公开(公告)日：2020-04-09
申请号：PCT/CN2018/109248
申请日：2018-10-05
申请人： ENTIT SOFTWARE LLC , ZHANG, Li , ZHANG, Bing , SUN, Da-Long , CHEN, Rong-Feng
发明人： ZHANG, Li , ZHANG, Bing , SUN, Da-Long , CHEN, Rong-Feng
IPC分类号： G06F3/048
摘要： A computing device includes a processor and a machine-readable storage medium storing instructions. The instructions are executable by the processor to: generate a graphical user interface including a first portion and a second portion, the first portion including a tree menu comprising a plurality of topic links; and in response to a user selection of a first topic link in the tree menu, present a first topic window in the second portion of the graphical user interface. The instructions are further executable by the processor to, in response to a user command to minimize the first content window: minimize the first content window; and present a snapshot window in the second portion of the graphical user interface, the snapshot window comprising a first snapshot of the first topic window.

54. 发明申请

WO2019183926A1 DYNAMIC CONTEXTUAL MENU 审中-公开
公开(公告)号：WO2019183926A1
公开(公告)日：2019-10-03
申请号：PCT/CN2018/081345
申请日：2018-03-30
申请人： ENTIT SOFTWARE LLC , ZHANG, Bing , SUN, Da-Long , ZHANG, Li , CHEN, Rong-Feng
发明人： ZHANG, Bing , SUN, Da-Long , ZHANG, Li , CHEN, Rong-Feng
IPC分类号： G06F3/0488 , G06F3/0482 , G06F3/0486
摘要： Content items and a dynamic menu element are displayed. Responsive to selection and dragging of the dynamic menu element over a particular content item, a menu of actions contextual to the particular content item is displayed, and the particular content item is highlighted to indicate that the displayed menu is related to the particular content item. Responsive to release of the dynamic menu element over the particular content item, the displayed menu is rendered actionable so that the actions thereof selectable; prior to release of the dynamic menu element over the particular content item, the displayed menu is non-actionable and no action is selectable. Responsive to selection of a specific action of the menu being displayed, the selected specific action is performed in relation to the particular content item.

55. 发明申请

WO2019152184A3 APPARATUS AND METHOD FOR OBJECT RECOGNITION 审中-公开
公开(公告)号：WO2019152184A3
公开(公告)日：2019-08-08
申请号：PCT/US2019/013641
申请日：2019-01-15
申请人： GLASNER, Daniel , GUAN, Lei , HANINA, Adam , ZHANG, Li
发明人： GUAN, Lei , HANINA, Adam , ZHANG, Li
IPC分类号： G06K9/46
摘要： A system and method for recognizing an object. The system includes an imaging apparatus for capturing an image of an object and a processor for receiving the captured image of the object, and for, when it is determined that fewer than a predetermined number of objects have been previously imaged, for determining whether the image of the captured object includes one or more characteristics determined to be similar to a same characteristic in a group of previously imaged objects so that the captured image is grouped with the previously imaged objects, or whether the image of the captured object includes one or more characteristics determined to be dissimilar to a same characteristic in a group of previously imaged objects so that the captured image is not grouped with the previously imaged objects, and the image of the captured object starts another group of previously imaged objects.

56. 发明申请

WO2014048065A1 TRIAZOLYL DERIVATIVES AS SYK INHIBITORS 审中-公开
标题翻译：三唑衍生物作为SYK抑制剂
公开(公告)号：WO2014048065A1
公开(公告)日：2014-04-03
申请号：PCT/CN2013/001132
申请日：2013-09-24
申请人： MERCK SHARP & DOHME CORP. , MERCK CANADA INC. , MACHACEK, Michelle R. , ROMEO, Eric T. , KATTAR, Solomon D. , CHRISTOPHER, Matthew , ALTMAN, Michael D. , NORTHRUP, Alan B. , ELLIS, John Michael , BOYLE, Brendan O' , DONOFRIO, Anthony , GRIMM, Jonathan , REUTERSHAN, Michael H. , CHILDERS, Kaleen Konrad , OTTE, Ryan D. , CASH, Brandon , DUCHARME, Yves , HAIDLE, Andrew M. , SPENCER, Kerrie , VITHARANA, Dilrukshi , WU, Lingyun , ZHANG, Li , ZHANG, Peng , BEAULIEU, Christian , GUAY, Daniel
发明人： MACHACEK, Michelle R. , ROMEO, Eric T. , KATTAR, Solomon D. , CHRISTOPHER, Matthew , ALTMAN, Michael D. , NORTHRUP, Alan B. , ELLIS, John Michael , BOYLE, Brendan O' , DONOFRIO, Anthony , GRIMM, Jonathan , REUTERSHAN, Michael H. , CHILDERS, Kaleen Konrad , OTTE, Ryan D. , CASH, Brandon , DUCHARME, Yves , HAIDLE, Andrew M. , SPENCER, Kerrie , VITHARANA, Dilrukshi , WU, Lingyun , ZHANG, Li , ZHANG, Peng , BEAULIEU, Christian , GUAY, Daniel
IPC分类号： C07D417/12 , C07D417/14 , C07D239/50 , A61K31/506 , A61P11/06 , A61P29/00 , A61P35/00
CPC分类号： C07D401/14 , A61K9/0019 , A61K9/0073 , A61K9/0075 , A61K9/10 , A61K9/2027 , A61K9/4858 , C07D239/42 , C07D403/12 , C07D405/12 , C07D405/14 , C07D409/12 , C07D409/14 , C07D413/14 , C07D417/14 , C07D471/04 , C07D498/04
摘要： Provided are triazole derivatives of Formula I which are potent inhibitors of spleen tyrosine kinase and pharmaceutical composition. The triazole derivatives are useful in the treatment and prevention of diseases mediated by said enzyme, such as asthma, COPD, rheumatoid arthritis, and cancer.
摘要翻译：提供式I的三唑衍生物，其是脾脏酪氨酸激酶和药物组合物的有效抑制剂。三唑衍生物可用于治疗和预防由所述酶介导的疾病，例如哮喘，COPD，类风湿性关节炎和癌症。

57. 发明申请

WO2014047860A1 UPLINK DOWNLINK ASSIGNMENT INDICATOR AMBIGUITY HANDLING FOR INTER-BAND TIME DIVISION DUPLEX CARRIER AGGREGATION 审中-公开
标题翻译： UPLINK下行链路分配指示符用于双带时间段双工载波聚合的业务处理
公开(公告)号：WO2014047860A1
公开(公告)日：2014-04-03
申请号：PCT/CN2012/082264
申请日：2012-09-28
申请人： NOKIA CORPORATION , NOKIA SIEMENS NETWORKS OY , LEI, Haipeng , YAO, Chunhai , ZHANG, Li
发明人： LEI, Haipeng , YAO, Chunhai , ZHANG, Li
IPC分类号： H04W40/00
CPC分类号： H04L1/1854 , H04L1/1812 , H04L1/1887 , H04L5/001 , H04L5/0055 , H04L5/1469 , H04W72/12
摘要： Various communication systems may benefit from techniques for handling inter-band carrier aggregation. For example, systems of the third generation partnership project (3 GPP) long term evolution (LTE) advanced (LTE-A) may benefit from a uplink (UL) downlink assignment indicator (DAI) ambiguity handling or inter-band time division duplex (TDD) carrier aggregation (CA). A method can include scheduling physical uplink shared channel in at least one primary cell and at least one secondary cell in a same subframe and granting a different uplink grant to the at least one primary cell and the at least one secondary cell. The method can alternatively include scheduling physical uplink shared channel in at least one serving cell in a subframe with uplink grant and scheduling physical downlink channel in at least another serving cell in following subframe. The method can also include avoiding codebook size confusion by handling uplink downlink assignment indicator ambiguity.
摘要翻译：各种通信系统可受益于处理带内载波聚合的技术。例如，第三代合作伙伴计划（3GGPP）长期演进（LTE）高级（LTE-A）的系统可以受益于上行链路（UL）下行链路分配指示符（DAI）模糊度处理或带内时分双工（ TDD）载波聚合（CA）。一种方法可以包括在同一子帧中的至少一个主小区和至少一个辅助小区中调度物理上行链路共享信道，并向所述至少一个主小区和所述至少一个辅助小区授予不同的上行链路许可。该方法可以替代地包括在具有上行链路许可的子帧中的至少一个服务小区中调度物理上行链路共享信道，并且在随后的子帧中的至少另一个服务小区中调度物理下行链路信道。该方法还可以通过处理上行链路下行链路分配指示符模糊来避免码本大小混淆。

58. 发明申请

WO2013159304A1 SWITCHING BETWEEN DOWNLINK AND UPLINK 审中-公开
标题翻译：下载和上传之间切换
公开(公告)号：WO2013159304A1
公开(公告)日：2013-10-31
申请号：PCT/CN2012/074726
申请日：2012-04-26
申请人： NOKIA SIEMENS NETWORKS OY , SKOV, Peter , ZHANG, Li
发明人： SKOV, Peter , ZHANG, Li
IPC分类号： H04W4/00
CPC分类号： H04W72/0413 , H04B7/2656 , H04L1/1887 , H04L5/0053 , H04L5/14 , H04L5/1469 , H04W72/0446
摘要： Communications of a time division duplex radio frame provided with at least one special subframe comprising at least one pilot period is provided such that at least one special subframe is used for signalling of critical control information. Other subframes of the radio frame than the at least one special subframe are flexibly allocated for use as downlink and uplink subframes of the radio frame.
摘要翻译：提供具有包括至少一个导频周期的至少一个特殊子帧的时分双工无线帧的通信，使得至少一个特殊子帧用于信令关键控制信息。无线帧的其他子帧比至少一个特殊子帧灵活地分配用作无线电帧的下行链路和上行链路子帧。

59. 发明申请

WO2013110219A1 VIRTUAL ANTENNA PORTS FOR FLEXIBLE CSI-RS RESOURCE DEFINITION 审中-公开
标题翻译：灵活的CSI-RS资源定义的虚拟天线端口
公开(公告)号：WO2013110219A1
公开(公告)日：2013-08-01
申请号：PCT/CN2012/070742
申请日：2012-01-29
申请人： NOKIA SIEMENS NETWORKS OY , SKOV, Peter , WANG, Chunye , WANG, Lilei , ZHANG, Li
发明人： SKOV, Peter , WANG, Chunye , WANG, Lilei , ZHANG, Li
IPC分类号： H04W72/04 , H04B7/26
CPC分类号： H04L27/2626 , H04B7/022 , H04B7/024 , H04B7/0426 , H04B7/0456 , H04B7/061 , H04B7/0617 , H04L5/0048 , H04L27/2646
摘要： An apparatus and a method are provided, by which at least one virtual antenna port is created which comprises a plurality of reference signal ports defined in a physical resource block. Information regarding the at least one virtual antenna port including the definition of the reference signal ports is sent to a user equipment, and reference signals are sent on the plurality of reference signal ports to the user equipment.
摘要翻译：提供了一种装置和方法，通过该装置和方法，创建包括在物理资源块中定义的多个参考信号端口的至少一个虚拟天线端口。关于包括参考信号端口的定义的至少一个虚拟天线端口的信息被发送到用户设备，并且参考信号在多个参考信号端口上被发送到用户设备。

60. 发明申请

WO2013102431A1 THERAPEUTICALLY ACTIVE COMPOUNDS AND THEIR METHODS OF USE 审中-公开
标题翻译：治疗活性化合物及其使用方法
公开(公告)号：WO2013102431A1
公开(公告)日：2013-07-11
申请号：PCT/CN2013/000009
申请日：2013-01-05
申请人： AGIOS PHARMACEUTICALS, INC. , CIANCHETTA, Giovanni , DELABARRE, Byron , POPOVICI-MULLER, Janeta , SALITURO, Francesco G. , SAUNDERS, Jeffrey O. , TRAVINS, Jeremy , YAN, Shunqi , GUO, Tao , ZHANG, Li
发明人： CIANCHETTA, Giovanni , DELABARRE, Byron , POPOVICI-MULLER, Janeta , SALITURO, Francesco G. , SAUNDERS, Jeffrey O. , TRAVINS, Jeremy , YAN, Shunqi , GUO, Tao , ZHANG, Li
IPC分类号： C07D251/18 , C07D251/26 , A61K31/53 , A61P35/00
CPC分类号： C07D401/14 , A61K31/53 , A61K31/5377 , C07D251/18 , C07D401/12 , C07D403/04 , C07D405/12 , C07D405/14 , C07D413/04 , C07D413/12 , C07D413/14 , C07D417/04 , C07D493/08
摘要： Provided are compounds useful for treating cancer and methods of treating cancer comprising administering to a subject in need thereof a compound described herein.
摘要翻译：提供的是用于治疗癌症的化合物和治疗癌症的方法，包括向有需要的受试者施用本文所述的化合物。

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