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41. 发明申请

WO2007072208A3 METAL COMPLEX POLYMER AND APPLICATION THEREOF 审中-公开
标题翻译：金属复合聚合物及其应用
公开(公告)号：WO2007072208A3
公开(公告)日：2009-04-16
申请号：PCT/IB2006003757
申请日：2006-12-22
申请人： CHANG KEN , ZHANG CAITENG
发明人： ZHANG CAITENG
IPC分类号： C05F5/00 , B01D53/34 , B01D71/08 , B01J20/24 , C05F11/02 , C07H3/00 , C07H5/06 , C07H13/00 , C07H23/00 , C08B37/00 , C08L1/00 , C08L5/00
CPC分类号： C12N1/20 , A01H4/001 , C12M21/02 , C12M21/04 , C12M27/20 , C12M29/26 , C12M41/24 , C12N1/12 , C12N1/26 , C12N5/0025 , C12P1/00 , C12P1/04 , Y02C10/08 , Y02E50/343 , Y02P30/20 , Y02W30/47
摘要： An oil product comprises a metal complex polymer solution for its esterification and fermentation reactions. The metal complex polymer is composed of oil, water, R-COOHs soluble saccharide (including sugar-metal) molecules, polymer with hydroxyl radical or hydroxyl radical with amino radical and/or carboxyl radical, saccharides (including polysaccharide-metal), metal salts, ammonia or amine substances and/or other mixtures. A fermentation of the metal complex polymer solution can be used for absorbing carbon dioxide, water, nitrogen and ions in the air to produce products including fatty acid and usnic acid for enzyme esterifications or other esterifications. The produced biomass diesel solution increases biological protein and its metabolite. Air/water/oil or air/water dissolution equipment is applied for absorbing gas or recycling combusted gas, deriving biological cell esterification to process waste solutions, processing organic wastes to produce fertilizers, feeds and food fermentations and producing organic gas.
摘要翻译：油品包含用于其酯化和发酵反应的金属络合物聚合物溶液。金属络合物聚合物由油，水，R-COOH可溶性糖（包括糖金属）分子，具有羟基或羟基的聚合物与氨基和/或羧基组成，糖（包括多糖 - 金属），金属盐，氨或胺物质和/或其它混合物。金属络合物聚合物溶液的发酵可用于吸收空气中的二氧化碳，水，氮和离子，以产生包含脂肪酸和芥酸的产物用于酶酯化或其它酯化。生产的生物柴油溶液增加生物蛋白及其代谢物。空气/水/油或空气/水溶解设备用于吸收气体或再循环燃烧气体，衍生生物细胞酯化反应处理废液，加工有机废物生产肥料，饲料和食品发酵以及生产有机气体。

42. 发明申请

WO2009017677A3 ALGAE GROWTH SYSTEM FOR OIL PRODUCTION 审中-公开
标题翻译：用于生产油脂的生长系统
公开(公告)号：WO2009017677A3
公开(公告)日：2009-03-19
申请号：PCT/US2008009063
申请日：2008-07-26
申请人： ECKELBERRY NICHOLAS , ECKELBERRY T RIGGS
发明人： ECKELBERRY T RIGGS
IPC分类号： C12M1/00 , C12M3/00
CPC分类号： C12M31/10 , C12M21/02 , C12M27/04 , C12M29/26
摘要： A biological growth reactor vessel for the cultivation of micro-algae, diatoms or other unicellular organisms, especially for oil production, is described which incorporates a light-transmitting fluid dispensing rod to which are attached a plurality of clear paddles which increase surface area for the diffusion of light and growth enhancing admixtures premixed at micron level. The dispensing rod incorporates a plurality of holes strategically placed to disperse the micron-mixture slurry of the growth admixtures. The dispensing rod is also used to introduce micro-bubbles, micron-mixed catalase enzymes and other cellulose break-down admixtures and gases to rupture cell walls for oil extraction.
摘要翻译：描述了用于培养微藻，硅藻或其它单细胞生物的生物生长反应器容器，特别是用于油生产的生物生长反应器容器，其包括透光流体分配棒，多个透明桨叶附接有多个透明桨叶，其增加表面积光的扩散和生长增强混合物以微米级预混合。分配杆包括多个孔，其策略性地放置以分散生长混合物的微米混合物浆料。分配棒还用于引入微气泡，微米混合的过氧化氢酶和其它纤维素分解的混合物和气体以破裂细胞壁用于抽油。

43. 发明申请

WO2004058937A1 ANALYTICAL DEVICE FOR CELL CULTURES 审中-公开
标题翻译：细胞培养分析装置
公开(公告)号：WO2004058937A1
公开(公告)日：2004-07-15
申请号：PCT/IT2002/000829
申请日：2002-12-24
申请人： ISTITUTO CLINICO HUMANITAS , PARMEGGIANI, Luciano , DIOGUARDI, Nicola , GRIZZI, Fabio
发明人： PARMEGGIANI, Luciano , DIOGUARDI, Nicola , GRIZZI, Fabio
IPC分类号： C12M3/00
CPC分类号： C12M23/08 , C12M29/00 , C12M29/26 , C12M33/02 , C12M41/00 , C12M41/46 , C12M41/48 , G01N1/2813
摘要： The present invention relates to an analytical device (1) for cell cultures comprising a container (4) for cell cultures, a reservoir (2) for the storage of fresh culture medium for said cell cultures, pumping means (3) suitable to introduce said fresh culture medium into said container and to remove metabolised culture medium from the cell cultures of said of said container and a depositing device (5) suitable for depositing the metabolised culture medium removed from said container by means of said pumping means onto an analytical support (11).
摘要翻译：本发明涉及用于细胞培养物的分析装置（1），其包括用于细胞培养物的容器（4），用于储存用于所述细胞培养物的新鲜培养基的储存器（2），适于引入所述新鲜培养基进入所述容器并从所述容器的细胞培养物中除去代谢的培养基，以及沉积装置（5），其适于将通过所述泵送装置从所述容器中移出的代谢培养基沉积到分析支架（ 11）。

44. 发明申请

WO2004009756A1 PROLIFERATION AND DELIVERY APPARATUS 审中-公开
标题翻译：增加和递送装置
公开(公告)号：WO2004009756A1
公开(公告)日：2004-01-29
申请号：PCT/ZA2003/000092
申请日：2003-07-15
申请人： AGRICULTURAL RESEARCH COUNCIL , KEMIRA PHOSPHATES (PTY) LIMITED , HORN, Charles, Henry
发明人： HORN, Charles, Henry
IPC分类号： C12M1/26
CPC分类号： C12M33/04 , C12M23/14 , C12M23/28 , C12M23/54 , C12M29/26 , C12M33/12 , C12M37/00
摘要： A portable, disposable, unitary microorganism proliferation and delivery apparatus (10) is provided. The apparatus (10) comprises a proliferation chamber (12) for containing a growth medium (14); and an inoculation chamber (16) for containing an inoculum (18). The proliferation and inoculation chambers (12 and 16) are connected by a tube (19) defining a passage (20), which is closed by a separating means in the form of a septum (22). The inoculation chamber (16) is provided or defined by a flexible vial having a mouth (16.1) and the septum (22) closes the mouth. Opening means in the form of a spike (24) is mounted in the passage (20) directed at the septum (22). The mouth (16.1) of the inoculation chamber (16) is connected to one end of the tube (19) by an advancement means in the form of a screw thread connection (26).
摘要翻译：提供了便携式，一次性的，单一的微生物增殖和释放装置（10）。装置（10）包括用于容纳生长培养基（14）的增殖室（12）。和用于容纳接种物（18）的接种室（16）。增殖和接种室（12和16）通过限定通道（20）的管（19）连接，管（19）由隔膜（22）形式的分离装置封闭。接种室（16）由具有口（16.1）和隔膜（22）封闭嘴的柔性小瓶提供或限定。尖头（24）形式的开口装置安装在指向隔膜（22）的通道（20）中。接种室（16）的口（16.1）通过螺纹连接（26）形式的前进装置连接到管（19）的一端。

45. 发明申请

WO03012025A2 BIO-REACTOR 审中-公开
标题翻译：生物反应器
公开(公告)号：WO03012025A2
公开(公告)日：2003-02-13
申请号：PCT/DE0102902
申请日：2001-07-31
申请人： ERHARDT URSULA , ERHARDT CHRISTOPH
发明人： ERHARDT URSULA , ERHARDT CHRISTOPH
IPC分类号： B01J4/00 , C12M1/00 , C12M1/04 , C12N1/00 , C12M
CPC分类号： C12M29/26
摘要： A bio-reactor for cultivating cells, comprising a culture vessel, at least one gas supply and/or liquid feed in addition to supply devices for gases and/or liquids enabling gases or liquids to be fed to the culture vessel. A mixer device, especially a Venturi nozzle is arranged between the supply device and gas supply or liquid feed in order to mix gas and/or liquid from the gas supply or liquid feed.
摘要翻译：生物反应器中用于培养细胞，其包含具有一个或多个气体供应和/或一种或多种液体的模板，和供给的培养容器装置，用于气体和/或液体，借助于该气体和/或液体能够被供给到培养容器，其中，所述供给装置和气体供应源之间或液体模板上连接混合装置，特别是文丘里管，用于混合来自气体供应装置或液体进料装置的气体和/或液体。

46. 发明申请

WO00046354A1 APPARATUS AND METHODS FOR PRODUCING AND USING HIGH-DENSITY CELLS AND PRODUCTS THEREFROM 审中-公开
标题翻译：用于生产和使用高密度电池及其产品的装置和方法
公开(公告)号：WO00046354A1
公开(公告)日：2000-08-10
申请号：PCT/US2000/001568
申请日：2000-01-21
IPC分类号： C12M1/00 , C12M1/02 , C12M1/04 , C12M3/06 , C12N7/00 , C12N5/06 , C12N5/00 , C12M1/12
CPC分类号： C12M27/02 , C12M29/06 , C12M29/16 , C12M29/18 , C12M29/26 , C12M41/12 , C12M41/26 , C12M41/32 , C12M41/36
摘要： Disclosed and claimed is apparatus and methods for the growth of cells to high density, products therefrom and uses thereof. Also disclosed and claimed is the use of this method for the growth to high-density insect cells, such as the Spodoptera frugiperda Sf900+ cells at high cell density with wild type and recombinant baculoviruses to produce baculovirus and DNA or gene or expession products. The apparatus comprises three interconnected modules, the cell culturing loop (100), the media replenishment loop (200) and the hollow fiber dialysis device (300). Cells from the bioreactor (110) are transported through the lumen space (310) of hollow fiber dialysis device and media from the media replenishment loop (200) is pumped through the extra-lumen space (320). Prior to re-entering the bioreactor the cells with media have oxygen added via the oxygenator (151).
摘要翻译：公开并要求保护的是将细胞生长成高密度的产品及其用途的装置和方法。还公开并要求保护的是使用这种方法用于高密度昆虫细胞的生长，例如具有野生型和重组杆状病毒的高细胞密度的草地贪夜蛾Sf900 +细胞以产生杆状病毒和DNA或基因或表达产物。该装置包括三个互连的模块，细胞培养循环（100），培养基补充回路（200）和中空纤维透析装置（300）。来自生物反应器（110）的细胞通过中空纤维透析装置的管腔空间（310）输送，并且来自培养基补充回路（200）的介质被泵送通过管腔外空间（320）。在重新进入生物反应器之前，具有培养基的细胞通过氧合器（151）加入氧气。

47. 发明申请

WO99020737A1 AGITATING INCUBATOR, DISPENSER INCLUDING THE SAME, AND DISPENSING METHOD 审中-公开
标题翻译：药剂师，包括其的分配者和分配方法
公开(公告)号：WO99020737A1
公开(公告)日：1999-04-29
申请号：PCT/JP1998/002771
申请日：1998-06-22
IPC分类号： C12M1/02 , C12M1/00
CPC分类号： C12M29/06 , C12M29/26
摘要： A medium dispenser capable of preventing dripping of a solution and pulsating discharge causing variation of the quantity of dispensed medium and foams, and making it possible to reliably supply the medium at a suitable temperature while preventing local gelling of the medium and contamination with miscellaneous bacteria, wherein: a medium return tube (14) for returning the medium to a medium container (3) is connected to and branched from an intermediate part of a medium feed tube (11) acting as a medium flow passage for guiding the medium (2) from the medium container (3) to a nozzle (7) to allow the medium to circulate while it is kept warm at the time of non-dispensing, while the portion of the medium flow passage extending from the branching point of the medium return tube (14) at the medium feed tube (11) to the nozzle (7) is heated as a whole with auxiliary heating means (16); at the time of dispensing, a suitable quantity of the medium is supplied through throttle portions (50, 51) disposed at at least two positions of the tube (11) and having a diameter smaller than the diameter of the other portions of the passage; and a first stirrer (5a) inside the medium container (3) and a second stirrer (5b) inside a heating tank (6) are used to provide a uniform stirring and heat insulation inside the medium container.
摘要翻译：一种能够防止溶液滴落和脉动排放的介质分配器，引起分配介质和泡沫数量的变化，并且使得可以在适当的温度下可靠地供应介质，同时防止介质的局部胶凝和杂质污染，其中：用于将介质返回到介质容器（3）的介质返回管（14）连接到作为用于引导介质（2）的介质流动通道的介质进料管（11）的中间部分并从其分支，从介质容器（3）到喷嘴（7），以允许介质在不分配时保持温暖时循环，同时介质流动通道的部分从介质返回管的分支点延伸（14）在介质供给管（11）到喷嘴（7）的整体上被辅助加热装置（16）加热; 在分配时，通过设置在管（11）的至少两个位置并且具有小于通道的其它部分的直径的直径的节流部（50,51）供给合适量的介质; 并且在介质容器（3）内部的第一搅拌器（5a）和加热罐（6）内的第二搅拌器（5b）用于在介质容器内部提供均匀的搅拌和隔热。

48. 发明申请

WO1996039819A1 CARDIOVASCULAR BIOREACTOR APPARATUS AND METHOD 审中-公开
标题翻译：心脏生物反应器装置及方法
公开(公告)号：WO1996039819A1
公开(公告)日：1996-12-19
申请号：PCT/US1996009694
申请日：1996-06-07
申请人： ST. JUDE MEDICAL, INC.
发明人： ST. JUDE MEDICAL, INC. , ELIZONDO, David, R. , CAMPBELL, Todd, D. , TOTTEN, Robert, P.
IPC分类号： A01N01/02
CPC分类号： A01N1/00 , A01N1/02 , A01N1/0247 , C12M21/08 , C12M29/12 , C12M29/26 , C12M41/00
摘要： The invention involves a method and apparatus for processing biological material, such as heart valves and vascular grafts.
摘要翻译：本发明涉及用于处理生物材料的方法和装置，例如心脏瓣膜和血管移植物。

49. 发明申请

WO1991016415A1 SEMI-CONTINUOUS FERMENTATION METHOD AND DEVICE, DESIGNED IN PARTICULAR FOR THE INDUSTRIAL MANUFACTURE OF A BIOLOGICAL MIXTURE BASED ON PROPIONIC ACID 审中-公开
标题翻译：半连续发酵方法和设备，特别为基于丙酸的生物混合物的工业制造而设计
公开(公告)号：WO1991016415A1
公开(公告)日：1991-10-31
申请号：PCT/FR1991000302
申请日：1991-04-11
申请人： SOCIETE BRITECH S.A. , BOYAVAL, Patrick , COLOMBAN, Agnès , ROGER, Loic
发明人： SOCIETE BRITECH S.A.
IPC分类号： C12M01/12
CPC分类号： C12P7/52 , C12M29/18 , C12M29/26 , C12M41/18 , C12M41/26
摘要： The semi-continuous fermentation of a carbon-containing source for the manufacture of a biological mixture based on propionic acid according to an industrializable process is described. The device preferably includes a fermentation vat (6) comprising two external loops (9, 19) for circulating the fermented substrate. A first loop (9) stirs the fermented substrate while sampling the substrate and returning it to the fermentation vat (6). The second loop (19) extracts the propionic acid based biological mixture (21) thereby obtained and includes a biological mixture (21)/bacteria (23) separating module (22). The method thereby implemented is semi-continuous and consists of a series of fermentation/extraction cycles with complete recycling of the biomass, followed by partial recycling once a predetermined biomass concentration has been obtained.

50. 发明申请

WO2017108158A1 VERFAHREN UND ANLAGE ZUR BEHANDLUNG EINES IN EIN TRÄGERMEDIUM ZU IMPFENDEN KULTURMEDIUMS 审中-公开
标题翻译：在运输介质中处理培养介质的方法和设备
公开(公告)号：WO2017108158A1
公开(公告)日：2017-06-29
申请号：PCT/EP2016/002037
申请日：2016-12-02
申请人： GEA TDS GMBH
发明人： LÖW, Joachim
IPC分类号： C12M1/26 , A23C9/12 , C12M1/00
CPC分类号： C12M29/26 , A23C9/12 , A23C13/16 , A23C19/032
摘要： Die Erfindung betrifft ein Verfahren und eine Anlage zur Behandlung eines in ein Trägermedium (TM) zu impfenden Kulturmediums (KM), wobei das Trägermedium (TM), das eine Trägermedium-Temperatur (8) aufweist, mit dem Kulturmedium (KM), das eine Kulturmedium-Temperatur (£(KM)) aufweist, an einem Zielort (Z; Z1, Z2) diskontinuierlich geimpft wird. Das Verfahren und die Anlage, geeignet zur Durchführung des Verfahrens, sollen gegenüber bekannten Lösungen den Impfprozess energetisch optimieren, die Temperaturführung im Impfprozess verbessern und die Qualität des Kulturmediums sichern. Dies wird verfahrenstechnisch durch die Schritte (i) bis (vi) eines Impfzyklus erreicht.
摘要翻译：本发明涉及用于处理待接种到载体培养基（TM）中的培养基（KM）的方法和装置，所述载体培养基（TM）具有载体培养基温度（8）与具有培养基温度（（（KM））的培养基（KM）在目标部位（Z; Z1，Z2）不连续地接种。适合于实施该方法的过程和设备旨在优化对已知溶液的播种过程，改善播种过程中的温度行为并确保培养基的质量。这是通过接种周期的步骤（i）至（vi）程序地实现的。

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