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41. 发明申请

WO2016134107A1 VIRTUAL MAGNETIC TRANSMISSION LINES FOR COMMUNICATION AND POWER TRANSFER IN CONDUCTING MEDIA 审中-公开
标题翻译：导电介质中的通信和电力传输的虚拟磁传输线
公开(公告)号：WO2016134107A1
公开(公告)日：2016-08-25
申请号：PCT/US2016/018400
申请日：2016-02-18
申请人： ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY
发明人： DIAZ, Rodolfo, E. , YOUSEFI, Tara
IPC分类号： H02J50/23 , H02J50/12 , H04B5/00
CPC分类号： A61B5/40 , H01F2038/143 , H02J50/12 , H02J50/23 , H04B5/0037
摘要： System and method for wireless, low-loss transmission in conductive medium of a radio-frequency signal received by a passive array of magnetic dipole elements from a source magnetic dipole. The individual elements are separated from one another by a distance on the order of or less than a quarter-wavelength corresponding to resonant radio-frequency. An array individual elements of which are microscopically dimensioned form a neuronal transmitter that can be configured to be implanted into neuronal tissue such that a source dipole, disposed near a neuron, passes a signal representative of neuronal activity along the array to an outmost element and further to external receiver disposed near skull. Macroscopically-dimensioned embodiment is configured to be submerged into and operate in salty water.
摘要翻译：由来自源极偶极子的磁偶极子的无源阵列接收的射频信号的导电介质中的无线，低损耗传输的系统和方法。各个元件彼此分开距离对应于谐振射频的四分之一波长的数量级。其显微尺寸的阵列的单个元件形成神经元发射器，其可被配置为植入神经元组织中，使得设置在神经元附近的源偶极子将表示沿阵列的神经元活动的信号传递到最外部元件，并且进一步到靠近头骨的外部接收器。宏观尺寸的实施例被配置成浸没在咸水中并在咸水中操作。

42. 发明申请

WO2016118534A1 NONINVASIVE DETERMINATION OF CARDIAC HEALTH AND OTHER FUNCTIONAL STATES AND TRENDS FOR HUMAN PHYSIOLOGICAL SYSTEMS 审中-公开
标题翻译：心脏健康和人类生理系统的其他功能状态和趋势的非确定性测定
公开(公告)号：WO2016118534A1
公开(公告)日：2016-07-28
申请号：PCT/US2016/013968
申请日：2016-01-19
申请人： GOOGLE INC.
发明人： ROGERS, Jeffrey, L.
IPC分类号： A61B5/00 , A61B5/02 , A61B8/00 , A61B5/01 , A61B5/0255 , A61B5/0402 , A61B5/11 , G01K11/00
CPC分类号： A61B5/6891 , A47K13/30 , A61B5/0022 , A61B5/01 , A61B5/02028 , A61B5/0205 , A61B5/021 , A61B5/0255 , A61B5/0402 , A61B5/05 , A61B5/1032 , A61B5/1102 , A61B5/1126 , A61B5/40 , A61B5/42 , A61B5/441 , A61B5/45 , A61B5/4509 , A61B5/4528 , A61B5/4842 , A61B5/6892 , A61B5/6898 , A61B5/7246 , A61B5/7275 , A61B5/742 , A61B5/746 , A61B5/747 , A61B5/7475 , A61B8/06 , A61B8/0875 , A61B8/0883 , A61B8/14 , A61B8/4477 , A61B8/483 , A61B2505/07 , A61B2562/0204 , A61B2562/0233 , A61B2562/0247 , G01K11/006 , G06F19/00
摘要： This document describes the assessment of human physiological systems in a manner that can be applied throughout the population. Various noninvasive sensors (including wearable, passive contact and noncontact sensors) may be integrated into the furniture of a person's home (including a mat, a toilet-seat, a mirror and a bathtub). They can be used to detect vitals and other parameters and combined with mathematical models to assess the functional state of physiological systems. For example, the health of the cardiovascular system is ultimately determined by organ blood perfusion and molecular gas exchange. In lieu of measuring these functional metrics directly, noninvasive sensors are used to monitor cardiac pressures and volumes, along with pressure transit through the vascular to quantify cardiovascular health, presenting little if any risk to the person and are simple and easy to use. In particular, cardiac pressure-volume loops are determined at different points in time and a health trend for the physiological system is determined based thereon.
摘要翻译：本文件以可应用于整个人群的方式描述人体生理系统的评估。各种无创传感器（包括可穿戴式，无源接触式和非接触型传感器）可以集成到人家的家具（包括垫，马桶座，镜子和浴缸）的家具中。它们可用于检测生命体和其他参数，并结合数学模型来评估生理系统的功能状态。例如，心血管系统的健康最终由器官血液灌注和分子气体交换决定。代替直接测量这些功能指标，无创传感器用于监测心脏压力和体积，以及通过血管的压力传递以量化心血管健康，对人体几乎没有风险，并且简单易用。特别地，在不同的时间点确定心脏压力 - 体积循环，并且基于此确定生理系统的健康趋势。

43. 发明申请

WO2016076886A1 SYSTEM FOR MOTOR REHABILITATION OF A PARETIC LIMB IN STROKE PATIENTS 审中-公开
标题翻译：用于电动修复肢体器官的系统
公开(公告)号：WO2016076886A1
公开(公告)日：2016-05-19
申请号：PCT/US2014/065703
申请日：2014-11-14
申请人： FUNDACION TECNALIA RESEARCH & INNOVATION , THE REGENTS OF THE UNIVERSITY OF CALIFORNIA , EBERHARD KARLS UNIVERSITAET TUEBINGEN
发明人： RAMOS MURGUIALDAY, Dr. Ander , BIRBAUMER, Niels , CARMENA RAMON, Jose Miguel
IPC分类号： A61B5/0488 , A61B5/04 , A61B5/11 , A61B5/00
CPC分类号： A61B5/04888 , A61B5/04012 , A61B5/1122 , A61B5/1124 , A61B5/1126 , A61B5/40 , A61B5/486 , A61B5/6868 , A61B2505/09 , G09B5/02 , G09B19/003
摘要： The invention relates to a system for motor rehabilitation of a paretic limb (102, 103) of a 5 patient (100) comprising: - a first plurality of sensors (10) couplable to pre-established positions of a head (101) of the patient (100) for registering brain neurosignals of the patient (100); - a body-actuator (30, 40) couplable to, at least, the paretic limb (102, 103); - a hybrid brain machine interface (200) for decoding brain neurosignals into 10 movements of the body-actuator (30,40); The system further comprises: - a second plurality of EMG sensors (20) couplable to the paretic limb (102, 103) for registering its EMG activity; - means for providing the patient (100) with instructions relative to a series of 15 exercises and/or tasks to be carried out with the paretic limb (102, 103); and in that upon carrying out a series of training sessions, each session comprising at least a set of such instructions, the hybrid brain machine interface (200) is configured to switch between controlling the movements of the body-actuator (30, 40) based on the decoded brain neurosignals and a hybrid control of the movements of the body-actuator 20 (30, 40), when a significant level of decodable EMG activity has been registered, the hybrid control being an EMG-gated brain control. The invention also relates to a method for motor rehabilitation of the paretic limb (102, 103).
摘要翻译：本发明涉及一种用于5例患者（100）的麻痹肢体（102,103）的马达康复系统，包括： - 第一多个传感器（10），可耦合到所述头部（101）的预先建立的位置用于登记患者（100）的脑神经信号的患者（100）; - 至少与所述麻痹肢（102,103）连接的身体致动器（30,40）; - 用于将脑神经信号解码为身体致动器（30,40）的10个运动的混合脑机接口（200）; 所述系统还包括： - 第二组多个EMG传感器（20），可耦合到所述麻痹肢体（102,103），用于记录其EMG活动; - 用于向所述患者（100）提供关于要与所述麻痹肢体（102,103）一起执行的一系列15次锻炼和/或任务的指令的装置; 并且在执行一系列训练时，每个会话至少包括一组这样的指令，混合脑机接口（200）被配置为在控制身体致动器（30,40）的运动之间进行切换在解码的脑神经信号和身体 - 致动器20（30,40）的运动的混合控制中，当已经登记了显着水平的可解码的EMG活动时，混合对照是EMG门控脑控制。本发明还涉及一种用于复位肢体（102,103）的运动康复的方法。

44. 发明申请

WO2015123255A1 SENSING AND STIMULATION SYSTEM 审中-公开
标题翻译：感觉和刺激系统
公开(公告)号：WO2015123255A1
公开(公告)日：2015-08-20
申请号：PCT/US2015/015352
申请日：2015-02-11
申请人： MEDTRONIC, INC.
发明人： HARDING, William , MARK, Scott
IPC分类号： A61B5/0408
CPC分类号： A61N1/0476 , A61B5/0002 , A61B5/0008 , A61B5/0024 , A61B5/01 , A61B5/04085 , A61B5/05 , A61B5/1104 , A61B5/224 , A61B5/40 , A61B5/42 , A61B5/45 , A61B5/4824 , A61B5/4836 , A61B5/4851 , A61B5/6811 , A61B5/686 , A61B5/6867 , A61B5/6877 , A61B2560/0214 , A61B2562/0247 , A61B2562/0271 , A61B2562/04 , A61B2562/125 , A61B2562/227 , A61N1/0456 , A61N1/0492 , A61N1/05 , A61N1/0551 , A61N1/3605 , A61N1/36103
摘要： A sensing and stimulation system includes a central hub, and a plurality of flexible arms extending from the central hub. Each of the arms includes at least one electrode and at least one sensor. Each of the arms is configured to perform sensing and stimulation including electrically stimulating biological material, and sensing biological responses and changes. The system includes a port configured to be alternatively connected to a remote control module for wireless operation of the system and a leaded connector for wired operation of the system.
摘要翻译：感测和刺激系统包括中心毂和从中心毂延伸的多个柔性臂。每个臂包括至少一个电极和至少一个传感器。每个臂被配置为执行感测和刺激，包括电刺激生物材料，以及感测生物反应和变化。该系统包括被配置为交替地连接到用于系统的无线操作的远程控制模块的端口和用于系统的有线操作的有引导连接器。

45. 发明申请

WO2015120438A1 SYSTEMS, METHODS, AND DEVICES FOR MEASURING EYE MOVEMENT AND PUPIL RESPONSE 审中-公开
标题翻译：用于测量眼睛运动和血压反应的系统，方法和装置
公开(公告)号：WO2015120438A1
公开(公告)日：2015-08-13
申请号：PCT/US2015/015179
申请日：2015-02-10
申请人： BRIEN HOLDEN VISION DIAGNOSTICS
发明人： CORNSWEET, Tom, N. , PETERSON, Paul , BOWER, Brad
IPC分类号： A61B3/024 , A61B3/113
CPC分类号： A61B3/113 , A61B3/08 , A61B3/111 , A61B3/112 , A61B3/145 , A61B5/40
摘要： A device for monitoring eye movement and pupil response that comprises a first optical pathway for displaying one or more images to the eyes of a patient and a second optical pathway for obtaining images of the eyes of a patient. The device further comprises at least one screen for displaying an image to the left eye of the patient which is not visible to the right eye of the patient and for displaying an image to the right eye of the patient which is not visible to the left eye of the patient; a first camera for capturing images of the left eye of the patient; and a second camera for capturing images of the right eye of the patient at substantially the same time as the first camera is capturing images of the left eye of the patient. The device also comprises at least one IR light source for illuminating the eyes of the patient; and a processor for processing the obtained images and measuring pupil response and/or eye movements.
摘要翻译：一种用于监测眼睛运动和瞳孔响应的装置，包括用于向患者的眼睛显示一个或多个图像的第一光学路径和用于获得患者眼睛的图像的第二光学路径。该装置还包括至少一个屏幕，用于向患者的左眼显示图像，其对于患者的右眼不可见，并且用于向左眼不可见的患者的右眼显示图像的病人用于捕获患者左眼的图像的第一相机; 以及第二相机，用于在与第一相机正在捕获患者的左眼的图像的基本同时捕获患者的右眼的图像。该装置还包括用于照亮患者眼睛的至少一个IR光源; 以及用于处理所获得的图像并测量瞳孔响应和/或眼睛运动的处理器。

46. 发明申请

WO2013146779A1 ラマン散乱分光法による神経検出法审中-公开
标题翻译：通过拉曼散射光谱进行神经检测的方法
公开(公告)号：WO2013146779A1
公开(公告)日：2013-10-03
申请号：PCT/JP2013/058775
申请日：2013-03-26
申请人：京都府公立大学法人
发明人：高松　哲郎 , 南川　丈夫 , 原田　義規
IPC分类号： A61B10/00 , G01N21/65 , G01N33/48
CPC分类号： A61B5/0075 , A61B5/40 , A61B5/742 , G01N21/65
摘要：本発明は、神経の検出方法であって、以下の工程（１）～（４）：工程１：試料に励起光を照射する工程工程２：試料からのラマン散乱光を検出する工程；工程３：工程２により検出されたラマン散乱光の特定範囲内の波数の強度比を算出する、あるいは前記強度比の特徴を抽出し多変量解析及び/又は統計解析する工程、工程４：前記強度比又は多変量解析及び/又は統計解析結果を指標として、無髄神経を含む神経を特異的に表示する工程を含むことを特徴とする、神経の検出方法を提供する。
摘要翻译：本发明提供一种检测神经的方法，其特征在于包括以下步骤（1）至（4）。步骤（1）：用激发光照射样品的步骤; 步骤（2）：检测来自样品的拉曼散射光的步骤; 步骤（3）：计算在步骤（2）中检测到的拉曼散射光的特定范围内的波数的强度比，或者提取和运行多变量分析和/或统计分析的步骤强度比; 步骤（4）：以多变量分析和/或统计分析的强度比或结果为指标，特异性显示包括无髓神经的神经的步骤。

47. 发明申请

WO2013142771A1 DEVICE TO MEASURE PUPILLARY LIGHT REFLEX IN INFANTS AND TODDLERS 审中-公开
标题翻译：测量婴幼儿轻度反射的设备
公开(公告)号：WO2013142771A1
公开(公告)日：2013-09-26
申请号：PCT/US2013/033457
申请日：2013-03-22
申请人： THE CURATORS OF THE UNIVERSITY OF MISSOURI
发明人： YAO, Gang , MILES, Judith H. , DINALANKARA, Dinalankara M.R.
IPC分类号： A61B3/113 , A61B3/14
CPC分类号： A61B3/112 , A61B5/1114 , A61B5/1128 , A61B5/168 , A61B5/40
摘要： The present disclosure provides a pupillary light reflex (PLR) system (10), wherein the PLR system includes a remote tracking and imaging system (46) that is structured and operable to generate and acquire high resolution pupil stimulus and response data from a test subject while the test subject is moving and is disposed a distance from remote tracking and imaging system (46) that is greater than or equal to one-third of a meter. The PLR system (10) additionally includes a computer based system controller (38) that is structure and operable to execute PLR software to control the operation of the remote tracking and imaging system (46) and compute PLR information based on the pupil stimulus and response data acquired as the test subject is moving.
摘要翻译：本公开提供了一种瞳孔光反射（PLR）系统（10），其中PLR系统包括远程跟踪和成像系统（46），其被构造和可操作以从测试对象产生并获取高分辨率瞳孔刺激和响应数据而测试对象正在移动并与距离远程跟踪和成像系统（46）相隔一定距离大于或等于一米的三分之一。 PLR系统（10）还包括基于计算机的系统控制器（38），其被构造并且可操作以执行PLR软件以控制远程跟踪和成像系统（46）的操作并且基于瞳孔刺激和响应来计算PLR信息作为测试对象获取的数据正在移动。

48. 发明申请

WO2013069820A1 DETECTING METHOD OF LIFE ACTIVITY, CONTROLLING METHOD OF LIFE ACTIVITY, AND TRANSMISSION METHOD OF INFORMATION CONCERNING LIFE ACTIVITY 审中-公开
标题翻译：生活活动的检测方法，生活活动的控制方法和关于生活活动的信息传递方法
公开(公告)号：WO2013069820A1
公开(公告)日：2013-05-16
申请号：PCT/JP2012/079874
申请日：2012-11-09
申请人： ANDO, Hideo
发明人： ANDO, Hideo
IPC分类号： G01N21/35 , A61B5/05 , A61B10/00 , G01N21/17
CPC分类号： A61B5/0075 , A61B5/0013 , A61B5/0059 , A61B5/0068 , A61B5/055 , A61B5/40 , A61B5/4041 , A61B5/4519 , A61B5/486 , A61B5/7228 , A61B5/7246 , A61B2562/0242 , A61B2576/00 , G01P13/00
摘要： According to a measuring method or a control method of life activity, a life object is illuminated with an electromagnetic wave including a wavelength in a designated waveband, and a characteristic in a local area of the life object is detected, or a life activity thereof is controlled. This "local area" is an area constituted by one or more cells. The "designated waveband" is defined based on any one of the following phenomena: [1] transition energy between a ground state of a vibration mode newly occurring between atoms in a constituent molecule of a cell membrane and a plurality of excited states; [2] transition energy between vibration modes occurring between specific atoms in a molecule corresponding to the activity of the life object or the change thereof; and [3] a specific chemical shift value in Nuclear Magnetic Resonance.
摘要翻译：根据生命活动的测量方法或控制方法，利用包括指定波段中的波长的电磁波照射生命对象，并且检测生命对象的局部区域的特征，或其寿命是受控。该“局部区域”是由一个或多个单元构成的区域。基于以下任一现象来定义“指定波段”：[1]在细胞膜的构成分子中的原子之间新发生的振动模式的基态与多个激发态之间的过渡能量; [2]在分子中的特定原子之间发生的振动模式之间的过渡能量对应于寿命对象的活动或其变化; 和[3]核磁共振中的特定化学位移值。

49. 发明申请

WO2013006626A3 FLOOR MAT SYSTEM AND ASSOCIATED, COMPUTER MEDIUM AND COMPUTER-IMPLEMENTED METHODS FOR MONITORING AND IMPROVING HEALTH AND PRODUCTIVITY OF EMPLOYEES 审中-公开
标题翻译：地板系统及相关的计算机中介和计算机实施方法，用于监测和改善员工的健康和生产力
公开(公告)号：WO2013006626A3
公开(公告)日：2013-05-10
申请号：PCT/US2012045414
申请日：2012-07-03
申请人： SAUDI ARABIAN OIL CO , HORSEMAN SAMANTHA J , ARAMCO SERVICE COMPANY
发明人： HORSEMAN SAMANTHA J
IPC分类号： G06F19/00 , A61B5/00
CPC分类号： A61B5/0008 , A61B5/002 , A61B5/01 , A61B5/02055 , A61B5/021 , A61B5/0537 , A61B5/08 , A61B5/1113 , A61B5/1114 , A61B5/145 , A61B5/40 , A61B5/4872 , A61B5/6803 , A61B5/6887 , A61B5/6891 , A61B5/6892 , A61B5/6897 , A61B5/6898 , A61B5/72 , A61B5/7275 , A61B5/7282 , A61B5/742 , G06F19/3418 , G16H15/00
摘要： Provided are embodiments of systems, computer medium and computer- implemented methods for sensing health characteristics of a user using a floor mat including a set of health sensors integrated therewith. The set of health sensors including temperature sensors, body position sensors, and body fat sensors. A method including receiving, from the temperature sensors, temperature data corresponding to a sensed body temperature of the user, receiving, from the body position sensors, body position data corresponding to a sensed body position of the user, receiving, from the body fat sensors, body fat data corresponding to a sensed body fat of the user, and transmitting, to a computer workstation, health data corresponding to the temperature data, the body position data, and the body fat data for use in determining the body temperature, the body position, and the body fat of the user.
摘要翻译：提供了系统，计算机介质和计算机实现的方法的实施例，用于使用包括与其集成的一组健康传感器的地板垫来感测使用者的健康特征。一套健康传感器，包括温度传感器，身体位置传感器和身体脂肪传感器。一种方法，包括从所述温度传感器接收对应于所感测到的体温的温度数据，从身体位置传感器接收与身体感测到的身体位置相对应的身体位置数据，从身体脂肪传感器身体脂肪数据对应于用户感觉到的身体脂肪，并且向计算机工作站发送对应于用于确定体温的温度数据，身体位置数据和身体脂肪数据的健康数据，身体位置，以及使用者的身体脂肪。

50. 发明申请

WO2013062684A1 MRI TRACTOGRAPHY BASED TRANSIT TIME DETERMINATION FOR NERVE OR MUSCLE FIBERS 审中-公开
标题翻译：用于神经或肌肉纤维的MRI基于TRACTOGRAPHY的交通时间确定
公开(公告)号：WO2013062684A1
公开(公告)日：2013-05-02
申请号：PCT/US2012/055458
申请日：2012-09-14
申请人： THE UNITED STATES OF AMERICA, as represented by The Secretary, DEPT. OF HEALTH AND HUMAN SERVICES , BASSER, Peter, J.
发明人： BASSER, Peter, J.
IPC分类号： G01R33/563 , G01R33/56
CPC分类号： G01R33/5608 , A61B5/055 , A61B5/40 , G01R33/56341
摘要： Magnetic resonance methods comprise tractographically establishing a path along a structure in a specimen and finding a distribution of structure radii or cross- sectional areas along the path. Based on the distribution and the path, end-to-end functional characteristics of the structure are estimated. For example, nerve transit times or distributions of transit times can be estimated for a plurality of nervous system locations such as Brodmann areas. Comparison of estimated transit times or distributions thereof between reference values or other values from the same structure can be used to assess specimen health.
摘要翻译：磁共振方法包括沿着沿着样本中的结构的轨迹建立路径，并找到沿着路径的结构半径或横截面积的分布。根据分布和路径，估计结构的端到端功能特征。例如，可以对多个神经系统位置（例如Brodmann区域）估计神经运送时间或运输时间的分布。参考值或相同结构的其他值之间的估计转运时间或其分布的比较可用于评估样本健康。

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