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41. 发明申请

WO2006050031A2 SYSTEM AND METHOD FOR ANALYTE SAMPLING AND ANALYSIS WITH ERROR CORRECTION 审中-公开
标题翻译：用于分析采样的系统和方法以及具有错误校正的分析
公开(公告)号：WO2006050031A2
公开(公告)日：2006-05-11
申请号：PCT/US2005/038784
申请日：2005-10-27
申请人： SONTRA MEDICAL CORPORATION , CHUANG, Han
发明人： CHUANG, Han
IPC分类号： A61B17/20
CPC分类号： A61B5/681 , A61B5/14514 , A61B5/1486 , A61B5/150022 , A61B5/150083 , A61B5/150358 , A61B5/150969 , A61B5/15134 , A61B5/157 , A61B10/0045 , A61B2010/0003 , G06F19/00
摘要： The invention relates to a transdermal analyte monitoring system comprising a medium adapted to interface with a biological membrane and to receive an analyte from the biological membrane and an electrode assembly comprising a plurality of electrodes, wherein the medium is adapted to react continuously with the analyte, an electrical signal is detected by the electrode assembly, and the electrical signal correlates to an analyte value. The analyte value may be the flux of the analyte through the biological membrane or the concentration of the analyte in a body fluid of a subject. The medium may comprise a vinyl acetate based hydrogel, an agarose based hydrogel, or a polyethylene glycol diacrylate (PEG-DA) based hydrogel, for example. The surface region of the electrode may comprise pure platinum. The system may include an interference filter located between the biological membrane and the electrode assembly for reducing interference in the system. The system may comprise a processor programmed to implement and error correction method that corrects for sensor drift.
摘要翻译：本发明涉及透皮分析物监测系统，其包括适于与生物膜接触并接收来自生物膜的分析物的介质和包括多个电极的电极组件，其中所述介质适于与分析物连续反应，电信号由电极组件检测，并且电信号与分析物值相关。分析物值可以是通过生物膜的分析物的通量或受试者的体液中分析物的浓度。介质可以包括基于乙酸乙烯酯的水凝胶，基于琼脂糖的水凝胶或基于聚乙二醇二丙烯酸酯（PEG-DA）的水凝胶。电极的表面区域可以包括纯铂。该系统可以包括位于生物膜和电极组件之间的干涉滤光器，用于减少系统中的干扰。该系统可以包括编程为实现的处理器和纠正传感器漂移的纠错方法。

42. 发明申请

WO1996018902A1 TEST SET FOR ANALYSIS OF BODY FLUIDS, PROCESS FOR PRODUCING IT AND ANALYTICAL PROCEDURE 审中-公开
标题翻译：测试集用于分析体液，工艺用于生产和分析程序
公开(公告)号：WO1996018902A1
公开(公告)日：1996-06-20
申请号：PCT/EP1995004812
申请日：1995-12-07
申请人： M & M DENTAL-MEDIZIN GMBH , MÖLL, Claus-Jürgen , PAESSENS, Theodor , ALTHOFF, Jörg
发明人： M & M DENTAL-MEDIZIN GMBH
IPC分类号： G01N33/543
CPC分类号： C12Q1/04 , A61B10/0051 , A61B2010/0003 , Y10S436/81 , Y10S436/811
摘要： The test set has a support (1) with an absorbent material (2) for collecting the body fluid and with a substance (4) that dissolves in the body fluid and provokes a certain reaction by the body and/or its microorganisms. The test set also has a device for determining medically relevant properties of the body fluid collected. The economical test set is designed to be used by the medical layman in a simple, quick and reliable operation and provides what is known as a provocation test.
摘要翻译：测试试剂盒包括与吸收材料（2）的载体（1）用于去除体液和与可溶性体液的主体和/或它的微生物挑衅质量（4）和装置的某些反应，用于确定医学相关体液的性质除去，更具体的pH值。廉价的检验试剂盒应该由医疗捻以简单，快速和安全的方式来处理，并允许所谓的激发试验。

43. 发明申请

WO9113355A3 ORAL COLLECTION FOR IMMUNOASSAY 审中-公开
标题翻译：口腔采集免疫
公开(公告)号：WO9113355A3
公开(公告)日：1991-10-03
申请号：PCT/US9101121
申请日：1991-02-27
申请人： EPITOPE INC
发明人： GOLDSTEIN ANDREW S , GAVOJDEA STEFAN , ZOGG DAVID F
IPC分类号： G01N1/04 , A61B10/00 , B01L3/00 , G01N20060101 , G01N1/10 , G01N33/00 , G01N33/50 , G01N33/53 , G01N33/569 , G01N33/571 , G01N33/576 , G01N33/68
CPC分类号： B01L3/502 , A61B10/0051 , A61B2010/0003 , A61B2010/0009 , G01N33/5302 , G01N33/6854
摘要： A method and device for collecting immunoglobulins and other analytes from the oral cavity for immunological and other testing. The device is a treated absorbent pad used to collect a specimen having a high concentration of immunoglobulins or other analytes. The specimen can be subjected to a basic immunological testing technique which can be used as a tool for screening a patient for diseases. A test kit is also provided.

44. 发明申请

WO2016066983A1 APPARATUS FOR TESTING A LIQUID SPECIMEN 审中-公开
标题翻译：用于测试液体样本的装置
公开(公告)号：WO2016066983A1
公开(公告)日：2016-05-06
申请号：PCT/GB2015/000285
申请日：2015-10-10
申请人： CLEVER MEDICAL LIMITED
发明人： BLACKWELL, Oliver
IPC分类号： A61B10/00 , B01L3/00
CPC分类号： B01L3/50825 , A61B10/007 , A61B2010/0003 , A61B2010/0006 , B01L3/5023 , B01L2200/023 , B01L2200/0615 , B01L2300/025 , B01L2300/042 , B01L2300/044 , B01L2300/046 , B01L2300/047 , B01L2300/0627 , B01L2300/0672 , B01L2300/0803 , B01L2300/0825 , B01L2300/0832
摘要： Apparatus (2) for testing a liquid specimen, which apparatus (2) comprises: (i) a container (4) for the liquid specimen; (ii) a lid (6) for closing the container (4) after the liquid specimen has been provided in the container (4); (iii) first securing means (8) by which the lid (6) is secured to the container (4); (iv) a test capsule (10) for securing to the lid (6) when the lid (6) is on the container (4); (v) second securing means (12) by which the test capsule (10) is secured to the lid (6); and (vi) a response chart (14) which is operable in response to contact with the liquid specimen, and the apparatus (2) being such that: (vii) the lid has an openable portion (18) which when opened permits a liquid specimen in the container (4) to enter the test capsule (10); (viii) the test capsule (10) has opener means (20) for opening the openable portion on the lid (6) when the test capsule (10) is secured to the lid (6); and (ix) the response chart (14) is inside the test capsule (10) and is contacted by the liquid specimen when the liquid specimen enters the test capsule (10).
摘要翻译：用于测试液体试样的装置（2），该装置（2）包括：（i）用于液体试样的容器（4）; （ii）用于在容器（4）中设置液体试样之后关闭容器（4）的盖子（6）; （iii）第一固定装置（8），盖子（6）通过该固定装置固定到容器（4）上; （iv）当盖子（6）在容器（4）上时，用于固定到盖子（6）的测试胶囊（10）; （v）第二固定装置（12），测试胶囊（10）通过该固定装置固定到盖子（6）上; 和（vi）响应于与液体试样的接触可操作的响应图（14），并且所述装置（2）使得：（vii）所述盖具有可打开部分（18），当打开时可以使液体容器（4）中的试样进入试验胶囊（10）; （viii）当测试胶囊（10）固定到盖子（6）上时，测试胶囊（10）具有用于打开盖子（6）上的可打开部分的开启装置（20）。和（ix）响应图（14）在测试胶囊（10）内部，并且当液体样本进入测试胶囊（10）时由液体样本接触。

45. 发明申请

WO2012050602A2 ORAL ENGAGEMENT ASSEMBLIES 审中-公开
标题翻译：口腔粘连组件
公开(公告)号：WO2012050602A2
公开(公告)日：2012-04-19
申请号：PCT/US2011001727
申请日：2011-10-06
申请人： NESTEC SA , SMITH REBECCA , BLAIR THOMAS J , NOTTINGHAM WILLIAM
发明人： SMITH REBECCA , BLAIR THOMAS J , NOTTINGHAM WILLIAM
IPC分类号： A61C19/04
CPC分类号： A61D5/00 , A01K15/026 , A46B2200/1086 , A61B10/0051 , A61B2010/0003 , A61B2010/0006 , A61B2010/0087 , A61C19/04
摘要： The invention provides oral engagement assemblies and methods of using the oral engagement assemblies. In a general aspect, the oral engagement assembly includes a mouthpiece comprising a handle and a support attached to the handle. A diagnostic receptacle is insertable into the mouth-piece to form the oral engagement assembly. One or more diagnostic sensors can be fixedly or releasably inserted into the diagnostic receptacle. The invention also provides kits useful for making the oral engagement assemblies and using such oral engagement assemblies for diagnosing a condition or disease in the animal.
摘要翻译：本发明提供口腔接合组件和使用口腔接合组件的方法。在一般方面，口部接合组件包括一个接口管，它包括一个手柄和一个附着在手柄上的支架。诊断容器可插入到口件中以形成口腔接合组件。一个或多个诊断传感器可以固定地或可释放地插入到诊断容器中。本发明还提供了用于制造口腔接合组件和使用这种口服接合组件来诊断动物中的病症或疾病的试剂盒。

46. 发明申请

WO2011091473A1 SAMPLING AND TESTING DEVICE FOR THE HUMAN OR ANIMAL BODY 审中-公开
标题翻译：人体或动物体的采样和测试装置
公开(公告)号：WO2011091473A1
公开(公告)日：2011-08-04
申请号：PCT/AU2011/000085
申请日：2011-01-27
申请人： RESPIRIO PTY LTD , PARSONS, Sean Andrew , DAHL, Steven David , MASCHMANN, Jennifer , WONG, Kon Euan Gerard , SPINK, Tim Ian , WILSON, Stephen Robert
发明人： PARSONS, Sean Andrew , DAHL, Steven David , MASCHMANN, Jennifer , WONG, Kon Euan Gerard , SPINK, Tim Ian , WILSON, Stephen Robert
IPC分类号： G01N33/53 , A61B10/00
CPC分类号： A61B5/15 , A61B5/0071 , A61B5/207 , A61B10/0038 , A61B10/0045 , A61B10/0048 , A61B10/0051 , A61B10/0058 , A61B10/0064 , A61B2010/0003
摘要： A device (1) is provided that is configured to indicate the presence or absence of one or more biological entities in a biological sample. The device comprises a sampling portion (11), the sampling portion comprising flexible material adjustably conformable to a part of a human or animal body, at least a portion of the sampling portion being absorbent and configured to receive a biological sample directly from the body; and a test portion (12) in fluid engagement with the sampling portion, the test portion comprising one or more test zones (14). The sampling portion and test portion are configured such that at least a portion of the sample received by the sampling portion is transferable to the test portion such as to contact one or more of the test zones, and wherein each test zone is configured to indicate the presence or absence of one or more biological entities in the sample.
摘要翻译：提供了一种设备（1），其被配置为指示生物样品中一种或多种生物实体的存在或不存在。所述装置包括采样部分（11），所述采样部分包括柔性材料，所述柔性材料可调节地与人体或动物体的一部分一致，所述采样部分的至少一部分是吸收并且构造成从身体直接接收生物样品; 和与采样部分流体接合的测试部分（12），测试部分包括一个或多个测试区域（14）。采样部分和测试部分被配置为使得由采样部分接收的样品的至少一部分可转移到测试部分，例如接触一个或多个测试区域，并且其中每个测试区域被配置为指示样品中存在或不存在一个或多个生物实体。

47. 发明申请

WO2010144321A1 DETERMINING AND/OR MONITORING PHYSIOLOGICAL CONDITIONS IN MAMMALS 审中-公开
标题翻译：确定和/或监测生理状况
公开(公告)号：WO2010144321A1
公开(公告)日：2010-12-16
申请号：PCT/US2010/037400
申请日：2010-06-04
申请人： REGAS, Philip, George Chelf , ANIMARK, INC.
发明人： REGAS, Philip, George Chelf
IPC分类号： A61B10/00
CPC分类号： A61B10/0012 , A61B5/053 , A61B10/0051 , A61B2010/0003 , A61B2010/0016 , A61B2010/0074 , A61B2017/00199
摘要： Improvements in a diagnostic system for determining and/or monitoring a physiological condition in a female mammal. The system includes hardware and software, and comprises algorithms for the recognition of predetermined patterns of data values, said algorithms being applied to said current daily data value and said stored daily data values by said microprocessor means, said microprocessor means controlling said display means to display characters representing one of several states of the mammal in response to recognition of a corresponding one of said predetermined patterns, wherein the algorithms are capable of automatically determining variables that can be used to define the beginning of the fertile cycle of the mammal, the end of the fertile cycle of the mammal and the most fertile day of the mammal the improvements of the present invention involve a novel user interface providing display of the physiological condition over time to the user.
摘要翻译：用于确定和/或监测女性哺乳动物的生理状况的诊断系统的改进。该系统包括硬件和软件，并且包括用于识别数据值的预定模式的算法，所述算法由所述微处理器装置应用于所述当前日数据值和所存储的每日数据值，所述微处理器装置控制所述显示装置显示响应于对所述预定模式中的相应一个的识别，所述算法能够自动确定可用于定义哺乳动物的可育周期的开始的变量，结束哺乳动物的肥沃周期和哺乳动物最肥沃的一天，本发明的改进涉及一种新颖的用户界面，用于随时间向用户显示生理状况。

48. 发明申请

WO2010028803A3 FLAT LANCET IMMOBILIZATION 审中-公开
标题翻译：平面网络化
公开(公告)号：WO2010028803A3
公开(公告)日：2010-05-27
申请号：PCT/EP2009006508
申请日：2009-09-08
申请人： ROCHE DIAGNOSTICS GMBH , HOFFMANN LA ROCHE
发明人： CHAN FRANK A , WONG DANIEL , RANEY CHARLES C , WIEGEL CHRISTOPHER , ROE STEVEN N
IPC分类号： A61B5/15
CPC分类号： A61B5/157 , A61B5/1411 , A61B5/14532 , A61B5/1468 , A61B5/150022 , A61B5/150213 , A61B5/150282 , A61B5/150358 , A61B5/150435 , A61B5/150503 , A61B5/150809 , A61B5/150816 , A61B5/150916 , A61B5/15142 , A61B5/1519 , A61B17/32093 , A61B2010/0003 , A61B2562/0295
摘要： A lancet enclosed in a sterility sheet forms a lancet packet to maintain the sterility of the lancet and prevent the lancet from unintentionally piercing the sterility sheet prior to lancet actuation. In one form, the lancet is immobilized by hot tack welding a portion of the sterility sheet to the lancet. Alternatively, portions of the sterility sheet are hot tack welded together through an opening in the lancet to limit movement of the lancet.
摘要翻译：包围在无菌片中的柳叶刀形成柳叶刀包，以维持刺血针的不整洁性，并防止刺血针在刺血针致动之前无意中刺穿无菌片。在一种形式中，通过将无菌片的一部分热定位焊接到刺血针来固定刺血针。或者，通过刺血针中的开口将无菌片的部分热定位焊接在一起，以限制刺血针的运动。

49. 发明申请

WO2009027935A2 BIOCHEMICAL SENSOR CARTRIDGE 审中-公开
公开(公告)号：WO2009027935A2
公开(公告)日：2009-03-05
申请号：PCT/IB2008053453
申请日：2008-08-27
申请人： KONINKL PHILIPS ELECTRONICS NV , NIEUWENHUIS JEROEN H , PELSSERS EDUARD G M , REIJNDORP JOCHEM , IMMINK ALBERT H J , MATTERS MARCO , MEUFFELS MARIA E H G
发明人： NIEUWENHUIS JEROEN H , PELSSERS EDUARD G M , REIJNDORP JOCHEM , IMMINK ALBERT H J , MATTERS MARCO , MEUFFELS MARIA E H G
IPC分类号： A61B10/00 , B01L3/00
CPC分类号： A61B10/0051 , A61B2010/0003 , B01L3/5023 , B01L3/5029 , B01L2300/022 , B01L2300/023 , B01L2300/0627
摘要： The invention relates to a (bio-)chemical sensor cartridge (100) for the examination of samples like blood or saliva, which comprises a sample collection element (e.g. a swab (120)), a sensor element (130) for sensing a parameter of interest, a sample transportation mechanism (110) for transferring the sample from the sample collection element (120) to the sensor element (130), and a connector (140) for linking the device to an external reader. The sample transportation mechanism (110) may particularly comprise a reservoir (111) with a buffer liquid that can be transferred via the sample collection element (120) to the sensor element (130). Moreover, the cartridge preferably consists of two parts (101, 102) that can reversibly be connected.

50. 发明申请

WO2008060882A3 FECAL OCCULT TEST PACKAGING 审中-公开
标题翻译： FECAL OCCULT测试包装
公开(公告)号：WO2008060882A3
公开(公告)日：2008-10-02
申请号：PCT/US2007083629
申请日：2007-11-05
申请人： KIKTA KEVIN J
发明人： KIKTA KEVIN J
IPC分类号： G01N21/77 , G01N1/28 , G01N33/50
CPC分类号： A61B10/0038 , A61B2010/0003
摘要： A specimen testing device, comprising: a folding top having a top inside and a top outside; a back portion having at least one flap opening in communication with the folding top; a front portion having at least one opening with the folding top covering the front portion and the front portion in communication with the back portion; a reagent test sheet affixed to the back portion the reagent test sheet interposed between the front portion and the back portion; at least one enclosed bubble containing developer attached to the inside of the flap opening of the back portion.
摘要翻译：一种试样测试装置，包括：折叠顶部，其具有顶部内部和顶部外部; 后部部分具有与折叠顶部连通的至少一个折片开口; 具有至少一个开口的前部，折叠顶部覆盖前部，前部与背部连通; 固定在后部的试剂测试片，插入在前部和后部之间的试剂测试片; 至少一个包含显影剂的封闭气泡，附着到后部的折片开口的内部。

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