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31. 发明申请

WO2015007811A1 DRIVE MECHANISM 审中-公开
标题翻译：驱动机制
公开(公告)号：WO2015007811A1
公开(公告)日：2015-01-22
申请号：PCT/EP2014/065330
申请日：2014-07-17
申请人： SANOFI
发明人： OAKLEY, Tom , SCHUMANN, Matt , PAWULSKI, Mark
IPC分类号： A61M5/20 , A61M5/315
CPC分类号： A61M5/31526 , A61M5/20 , A61M5/31535 , A61M5/31536 , A61M5/31551 , A61M5/31553 , A61M5/31558 , A61M5/31563 , A61M5/31578 , A61M5/31583 , A61M2005/3126
摘要： A drive mechanism (11) for a delivery device comprising -a drive member (17) for driving a piston rod (13); -a moveable dose setting member (19, 35) being decoupled from the drive member (17) in a dose setting state; the dose setting member (19, 35) being moveable in a drive direction in a dose delivery state, wherein the movement of the dose setting member (19, 35) is transferred to the drive member (17); and -a dose control means (49) being coupled to the dose setting member (19, 35) by a rack-and-pinion means (51, 67) in such a manner that the movement of the dose setting member (19, 35) is transferred to a movement of the dose control means (49), wherein the movement of the dose setting member (19, 35) is stopped when the dose control means (49) reaches an end position.
摘要翻译：一种用于输送装置的驱动机构（11），包括：用于驱动活塞杆（13）的驱动构件（17）。 - 可动剂量设定构件（19,35）在剂量设定状态下与所述驱动构件（17）分离; 所述剂量设定部件（19,35）能够在剂量输送状态下沿驱动方向移动，其中所述剂量设定部件（19,35）的移动被传递到所述驱动部件（17）。和 - 剂量控制装置（49），其通过齿条和小齿轮装置（51,67）以剂量设定构件（19,35）的移动方式联接到剂量设定构件（19,35））被转移到剂量控制装置（49）的移动，其中当剂量控制装置（49）到达结束位置时，剂量设定构件（19,35）的移动停止。

32. 发明申请

WO2015007810A1 DRIVE MECHANISM 审中-公开
标题翻译：驱动机制
公开(公告)号：WO2015007810A1
公开(公告)日：2015-01-22
申请号：PCT/EP2014/065329
申请日：2014-07-17
申请人： SANOFI
发明人： OAKLEY, Tom , SCHUMANN, Matt , PAWULSKI, Mark
IPC分类号： A61M5/20 , A61M5/315
CPC分类号： A61M5/31551 , A61M5/20 , A61M5/31535 , A61M5/31536 , A61M5/31553 , A61M5/31578 , A61M5/31583 , A61M2005/3126
摘要： A drive mechanism (11) for a delivery device comprising a drive member (17) for driving a piston rod (13); a moveable dose setting member (19, 35) being disengaged from the drive member (17) in a dose setting state and being moveable in a drive direction in a dose delivery state, wherein the dose setting member (19, 35) engages with the drive member (17) in the dose delivery state in such a manner that the movement of the dose setting member (19, 35) in the drive direction is transferred to the drive member (17); and a spring member (21) being coupled to the dose setting member (19, 35) in such a manner that the movement of the dose setting member (19, 35) in a setting direction loads the spring member (21) in the dose setting state, the spring force of the loaded spring member (21) driving the dose setting member (19, 35) in the drive direction in the dose delivery state.
摘要翻译：一种用于输送装置的驱动机构（11），包括用于驱动活塞杆（13）的驱动构件（17）。可动剂量设定部件（19,35）以剂量设定状态与驱动部件（17）脱离啮合并且能够在剂量输送状态下沿驱动方向移动，其中剂量设定部件（19,35）与驱动构件（17）以剂量设定构件（19,35）在驱动方向上的移动传递到驱动构件（17）的方式处于剂量递送状态; 以及弹簧构件（21），其以这样的方式联接到剂量设定构件（19,35），使得剂量设定构件（19,35）在设定方向上的移动以该剂量加载弹簧构件（21）在剂量输送状态下，驱动剂量设定部件（19,35）的驱动方向的负载弹簧部件（21）的弹簧力。

33. 发明申请

WO2013156345A2 MEDICAMENT DELIVERY DEVICE 审中-公开
标题翻译：药物递送装置
公开(公告)号：WO2013156345A2
公开(公告)日：2013-10-24
申请号：PCT/EP2013/057376
申请日：2013-04-09
申请人： CAREBAY EUROPE LTD
发明人： WIESELBLAD, Anders
CPC分类号： A61M5/31541 , A61M5/3155 , A61M5/31551 , A61M5/31576 , A61M5/31578 , A61M5/31585 , A61M5/31593
摘要： The present invention relates to a medicament delivery device, comprising a housing (10) having a proximal end (11) and a distal end (12); a hollow piston plunger (20) being arranged within the housing (10); a telescopic dose drum (40) being concentrically arranged between the housing (10) and the piston plunger (20), piston plunger driving means for driving the hollow piston plunger towards the proximal end, comprising a hollow drive drum sleeve (30) being movable arranged within the hollow piston plunger (20) and being fixedly connected to the telescopic dose drum (40), wherein the hollow drive drum sleeve (30) and the hollow piston plunger (20) are coupleable to each other; actuation means operably connected to said hollow drive drum sleeve, wherein the hollow drive drum sleeve (30) and the hollow piston plunger (20) are operationally coupled such that axial movement of the actuation means towards the proximal end forces the hollow drive drum sleeve (30) and the hollow piston plunger (20) to couple together whereby the hollow piston plunger (20) and the telescopic dose drum (40) are displaced towards the proximal end for delivering the set dose. The invention is characterized in that the device further comprises a stop body (26) for inhibiting rotation of the telescopic dose drum (40) and the drive drum sleeve (30) when the set dose equals the remaining dose in the medicament container.
摘要翻译：本发明涉及药物输送装置，其包括具有近端（11）和远端（12）的壳体（10）。设置在所述壳体（10）内的中空活塞柱塞（20）; 同轴地布置在壳体（10）和活塞柱塞（20）之间的伸缩剂量鼓（40），用于将中空活塞柱塞朝向近端驱动的活塞柱塞驱动装置，包括可移动的中空驱动鼓套筒（30）布置在所述中空活塞柱塞（20）内并且固定地连接到所述伸缩剂量鼓（40），其中所述中空驱动鼓套筒（30）和所述中空活塞柱塞（20）可彼此连接; 致动装置可操作地连接到所述中空驱动鼓套筒，其中中空驱动鼓套筒（30）和中空活塞柱塞（20）可操作地联接，使得致动装置朝向近端的轴向运动迫使中空驱动滚筒套筒 30）和中空活塞柱塞（20）连接在一起，由此中空活塞柱塞（20）和伸缩剂量鼓（40）朝向近端移位以传递设定剂量。本发明的特征在于，当设定的剂量等于药物容器中的剩余剂量时，该装置还包括用于禁止伸缩剂量鼓（40）和驱动鼓套筒（30）的旋转的止动体（26）。

34. 发明申请

WO2013098194A3 TORSION- SPRING BASED WIND-UP AUTOINJECTOR PEN WITH DIAL - UP/DIAL - DOWN DOSING MECHANISM 审中-公开
标题翻译： TORSION-弹簧式WIND-UP AUTOINJECTOR PEN，带拨号/拨号下放机器
公开(公告)号：WO2013098194A3
公开(公告)日：2013-09-06
申请号：PCT/EP2012076421
申请日：2012-12-20
申请人： NOVO NORDISK AS
发明人： HANSEN TORBEN STROEM , HEMMINGSEN HANS , NIELSEN CHRISTIAN HOEJRIS , KIILERICH EBBE , AVLUND MIKKEL , MELANDER MATIAS
IPC分类号： A61M5/20 , A61M5/31 , A61M5/315
CPC分类号： A61M5/3156 , A61M5/20 , A61M5/2033 , A61M5/31535 , A61M5/3155 , A61M5/31553 , A61M5/31578 , A61M5/31593 , A61M2005/3126 , A61M2005/3143 , A61M2205/42
摘要： The present invention relates to an automatic torsion spring based ijection device having a dial-up/dial-down mechanism by which a dose can be set by rotating a dose setting member in a first direction and which dose size can be reduced by rotating the same dose setting member in a second and opposite direction. The dial-up/dial-down mechanism operates a torsion spring which is strained when setting a dose and unstrained when rotating the dose setting element in the second direction. In order to secure the torsion spring when strained, a ratchet arm (21) following the rotation of the dose setting element in the first direction, engages a toothed element (10) such that engagement of the at least one ratchet arm (21 ) with teeth (12) of the toothed element (10) prevents unwinding of the torsion spring, and wherein the rotation of the dose setting member in the first direction moves the ratchet arm (21) from one tooth (12) to the subsequent tooth (12) of the toothed element (10), and rotation of the dose setting member in the second direction lowering the set dose activates the ratchet arm (21) to disengage the teeth (12) of the toothed element (10) and thereby allow the torsion spring to move the ratchet arm (21) in the second direction to the previous tooth (12) such that the force accumulated in the torsion spring reduces incrementally. In order to provide a smooth movement when dialling down the set dose, the at least one ratchet arm (21) is provided o a ratchet tube (20) which carries friction teeth (30) which engage with a cam curve (16) of the toothed element, dampening the movement of the ratchet arm (21) by the torsion spring.
摘要翻译：本发明涉及一种具有拨号/拨号机构的自动扭力弹簧式喷射装置，通过该拨号/拨下机构可以通过在第一方向上旋转剂量设定部件来设定剂量，并且可以通过旋转剂量尺寸来减小剂量大小剂量设定构件在第二和相反方向上。拨号/拨号机构操作扭转弹簧，当在第二方向上旋转剂量设定元件时，设定剂量并且不受约束时，扭转弹簧变形。为了在应变时固定扭簧，在剂量设定元件沿第一方向旋转之后的棘轮臂（21）接合齿形元件（10），使得至少一个棘轮臂（21）与齿形元件（10）的齿（12）防止扭转弹簧的退绕，并且其中剂量设定构件沿第一方向的旋转将棘轮臂（21）从一个齿（12）移动到随后的齿（12）），并且剂量设定构件沿着降低设定剂量的第二方向的旋转激活棘轮臂（21）以使齿形元件（10）的齿（12）脱离，从而允许扭转弹簧将棘轮臂（21）沿第二方向移动到先前的齿（12），使得累积在扭转弹簧中的力递增地减小。为了在拨下设定的剂量时提供平滑的运动，至少一个棘轮臂（21）设置在棘轮管（20）上，该棘轮管（20）承载摩擦齿（30），该摩擦齿与齿形的凸轮曲线（16）啮合通过扭转弹簧阻尼棘轮臂（21）的运动。

35. 发明申请

WO2011141253A1 PLUNGERPUMPE MIT MANUELLER EINGRIFFSMÖGLICHKEIT FÜR VOLUMEN UNTER EINEM MIKROLITER 审中-公开
标题翻译：与人工干预可能性卷下的1微升柱塞
公开(公告)号：WO2011141253A1
公开(公告)日：2011-11-17
申请号：PCT/EP2011/055698
申请日：2011-04-12
申请人： MMI AG , TSCHANZ, Peter
发明人： TSCHANZ, Peter
IPC分类号： F04B19/00
CPC分类号： F04B19/006 , A61M5/31578 , A61M5/31583 , F04B9/02 , H02K7/06
摘要： Eine automatisierte hochpräzise Plungerpumpe für Volumen unter einem Mikroliter, die bei der Mikroskop-gestützten Mikromanipulation von biologischem Material eingesetzt wird, umfasst ein Gehäuse (1) und einen Pumpkopf (8), der einen Arbeitsraum (9) mit einer gemeinsamen oder separaten Ein- und Auslassöffnung (10) definiert, wobei das Volumen des Arbeitsraums (9) durch einen in ihn einbringbaren axial beweglichen Plunger (7) veränderbar ist. Der Plunger (7) ist durch eine Gewindespindel (5) oder eine auf der Gewindespindel (5) in Gewindeeingriff befindliche Spindelmutter (6) axial beweglich ist und die Gewindespindel (5) und/oder die Spindelmutter (6) ist rotatorisch antreibbar und die jeweils andere ist rotatorisch arretierbar ausgelegt.
摘要翻译：一种自动化的高精度柱塞泵用于在微升，其在生物材料的基于显微镜的显微操作使用量，包括：壳体（1）和泵头部（8）和具有一个共同的或分开的输入和一个工作腔室（9）限定的排出开口（10），其中，所述工作腔（9）的由可插入的卷到它可轴向移动的柱塞（7）是可变的。所述柱塞（7），位于螺纹接合螺纹轴的主轴螺母（5）或在丝杠（5）（6）可轴向移动与螺纹轴（5）和/或心轴螺母（6）的旋转，并且每个被驱动其他设计旋转锁定。

36. 发明申请

WO2011039219A2 DRUG DELIVERY DEVICE, ASSEMBLY FOR A DRUG DELIVERY DEVICE AND METHOD FOR SETTING UP A DRUG DELIVERY DEVICE 审中-公开
标题翻译：药物递送装置，用于药物递送装置的组装和用于设置药物递送装置的方法
公开(公告)号：WO2011039219A2
公开(公告)日：2011-04-07
申请号：PCT/EP2010/064410
申请日：2010-09-29
申请人： SANOFI-AVENTIS DEUTSCHLAND GMBH , MACDONALD, Catherine Anne , VEASEY, Robert , KOUYOUMJIAN, Garen , JONES, Christopher , BAILEY, Alexander Ian
发明人： MACDONALD, Catherine Anne , VEASEY, Robert , KOUYOUMJIAN, Garen , JONES, Christopher , BAILEY, Alexander Ian
IPC分类号： A61M5/31
CPC分类号： A61M5/24 , A61M5/2448 , A61M5/3146 , A61M5/31571 , A61M5/31578 , A61M2005/2073 , A61M2005/2451
摘要： The instant application is directed to an assembly for a drug delivery device which is arranged to operate in two distinct modes, a priming mode starting from a pre-priming state and a dispense mode operating in a post-priming state, and a drug delivery device comprising this assembly. The assembly comprises a dose member (2), an actuating member (3) and a piston rod (7) which is configured to act on a bung (8) of an assembled cartridge (9) containing the drug. In the pre-priming state the actuating member (3) is configured to be moved by a user such that the movement of the actuating member (3) causes a movement of the dose member (2) and such that the movement of the dose member (2) causes a movement of the piston rod (7). In the post-priming state the dose member (2) is configured to be moved by a user without causing a movement of the actuating member (3) in order to perform a set and dispense action of the drug delivery device.
摘要翻译：本申请涉及用于药物递送装置的组件，其被布置成以两种不同模式操作，从预灌注状态开始的启动模式和以后启动状态操作的分配模式，以及药物递送装置包括该组件。该组件包括剂量构件（2），致动构件（3）和活塞杆（7），其构造成作用在装有药物的组装的药筒（9）的栓（8）上。在预启动状态下，致动构件（3）构造成由使用者移动，使得致动构件（3）的移动导致剂量构件（2）的移动，并且使得剂量构件（2）使活塞杆（7）移动。在后启动状态中，剂量构件（2）构造成由使用者移动而不引起致动构件（3）的移动，以便执行药物递送装置的凝固和分配动作。

37. 发明申请

WO2011006926A1 DRIVE ASSEMBLY FOR A PEN-TYPE INJECTOR AND PEN-TYPE INJECTOR WITH A DRIVE ASSEMBLY 审中-公开
标题翻译：用于笔式注射器和带有驱动装置的笔式喷射器的驱动装置
公开(公告)号：WO2011006926A1
公开(公告)日：2011-01-20
申请号：PCT/EP2010/060128
申请日：2010-07-14
申请人： SANOFI-AVENTIS DEUTSCHLAND GMBH , JONES, Mathew , JONES, Christopher , LANGLEY, Christopher
发明人： JONES, Mathew , JONES, Christopher , LANGLEY, Christopher
IPC分类号： A61M5/20 , A61M5/145
CPC分类号： A61M5/20 , A61M5/14566 , A61M5/31578 , A61M5/31583 , A61M2005/31518 , A61M2005/3152
摘要： A drive assembly (2) for a pen-type injector, comprising: a guiding means (40) having a first (42) and a second end (41), a drive means (20), an elongate member (30) coupled to the guiding means (40) and adapted to be driven by the drive means (20) for displacing the guiding means (40) with respect to the drive means (20), a piston member (60) displaceably disposed at the first end (42) of the guiding means (40) and an adjusting member (62) displaceably disposed at the second end (41) of the guiding means (40), wherein the drive means (20) is fixedly located with respect to the adjusting member (62), and wherein the piston member (60) and the adjusting member (62) are coupled such that the sum of the distance between the piston member (60) and the guiding means (40) and the distance between the adjusting means (62) and the guiding means (40) remains constant, and a pen-type injector with such a drive assembly.
摘要翻译：一种用于笔式注射器的驱动组件（2），包括：具有第一（42）和第二端（41）的引导装置（40），驱动装置（20），细长构件（30）所述引导装置（40）适于被所述驱动装置（20）驱动，用于使所述引导装置（40）相对于所述驱动装置（20）移动;可移动地设置在所述第一端（42）处的活塞构件）和可移动地设置在引导装置（40）的第二端（41）处的调节构件（62），其中驱动装置（20）相对于调节构件（62）固定地定位），并且其中所述活塞构件（60）和所述调节构件（62）联接成使得所述活塞构件（60）和所述引导装置（40）之间的距离和所述调节装置（62）之间的距离之和，并且引导装置（40）保持恒定，以及具有这种驱动组件的笔式注射器。

38. 发明申请

WO2010115743A1 MEDICAMENT DELIVERY DEVICE 审中-公开
标题翻译：药物递送装置
公开(公告)号：WO2010115743A1
公开(公告)日：2010-10-14
申请号：PCT/EP2010/054073
申请日：2010-03-29
申请人： SHL GROUP AB , HOLMQVIST, Anders
发明人： HOLMQVIST, Anders
IPC分类号： A61M5/315
CPC分类号： A61M5/20 , A61M5/31536 , A61M5/31555 , A61M5/31558 , A61M5/31575 , A61M5/31578 , A61M5/3158 , A61M2005/3152
摘要： The present invention relates to a medicament delivery device comprising an elongated housing (10, 10') having opposite distal and proximal ends, a medicament container (18; 18') arranged inside said housing, a medicament delivery member (16; 16') attachable to said medicament container; a plunger rod (22; 22') arranged to act on a stopper (20; 20') inside said medicament container; driving means arranged to interact with said plunger rod; wherein said device further comprises an operation member (38; 38') transversally protruding through an elongated opening (39; 39') on the longitudinal surface of the elongated housing and interactively connected to the driving means for both setting and actuating the delivery of a dose of medicament.
摘要翻译：本发明涉及药物输送装置，其包括具有相对的远端和近端的细长壳体（10,10'），布置在所述壳体内的药物容器（18; 18'），药物输送构件（16; 16'）可附接到所述药物容器; 布置成作用在所述药物容器内部的止动件（20; 20'）上的柱塞杆（22; 22'）; 布置成与所述柱塞杆相互作用的驱动装置; 其中所述装置还包括横向突出穿过细长壳体的纵向表面上的细长开口（39; 39'）并且与驱动装置交互地连接的操作构件（38; 38'），用于设置和致动一个剂量的药物。

39. 发明申请

WO2007099044A1 MEDICAL DEVICE WITH ORIENTATION SENSITIVE PRIMING MECHANISM 审中-公开
标题翻译：具有定向灵敏机制的医疗器械
公开(公告)号：WO2007099044A1
公开(公告)日：2007-09-07
申请号：PCT/EP2007/051561
申请日：2007-02-19
申请人： SHL MEDICAL AB , WIKNER, Jakob , BRUNNBERG, Lennart
发明人： WIKNER, Jakob , BRUNNBERG, Lennart
IPC分类号： A61M5/20 , A61M15/00 , A61M5/315
CPC分类号： A61M5/20 , A61M5/2448 , A61M5/3146 , A61M5/31551 , A61M5/31553 , A61M5/3156 , A61M5/31563 , A61M5/31578 , A61M5/31583 , A61M5/3204 , A61M5/326 , A61M11/007 , A61M11/02 , A61M15/009 , A61M2005/2013 , A61M2205/215 , A61M2205/276
摘要： The present invention relates to a device for a medical device, which medical device comprises a body (10, 12) , a container (24) containing medicament, the container further comprising an expelling passage, and delivery drive means (36) for expelling said medicament, wherein said device comprises mechanical priming drive means (57) and mechanical priming activation (40) means being arranged and designed such that said mechanical priming activation means is capable of permitting activation of said mechanical priming drive means only when the medical device is substantially vertical with the expelling passage into an specific direction.
摘要翻译：本发明涉及一种用于医疗装置的装置，该医疗装置包括主体（10,12），容纳药剂的容器（24），容器还包括排出通道，以及输送驱动装置（36），用于将所述药物，其中所述装置包括机械起动驱动装置（57）和机械起动激活（40）装置，其布置和设计成使得所述机械起动激活装置能够仅在医疗装置基本上垂直与排出通道进入特定方向。

40. 发明申请

WO2006077466A2 PEN SHAPED MEDICATION INJECTION DEVICES 审中-公开
标题翻译：笔式药物注射装置
公开(公告)号：WO2006077466A2
公开(公告)日：2006-07-27
申请号：PCT/IB2005003790
申请日：2005-12-16
申请人： WOCKHARDT AMERICAS INC , KNIGHT BARRY , KNOWLES STEPHEN , SRINIVAS VENKITRAMAN R , RAMESH SESHA
发明人： KNIGHT BARRY , KNOWLES STEPHEN , SRINIVAS VENKITRAMAN R , RAMESH SESHA
IPC分类号： A61K39/02
CPC分类号： A61M5/31578 , A61M5/24 , A61M5/3155 , A61M5/31551 , A61M5/31561 , A61M5/3158 , A61M5/31585 , A61M2005/2407 , A61M2005/2488 , A61M2205/581 , A61M2205/583 , A61M2205/585
摘要： The present invention provides a delivery device comprising a fluid cartridge holder, housing and a piston drive mechanism that comprises a hollow piston rod and a drive-shaft. The hollow piston rod has an internal thread that mates with the external thread of the drive-shaft, forming a thread connection and being axially restrained in the proximal direction relative to the housing. The drive mechanism is in turn connected to the housing via a one way ratchet such that the piston rod is prevented from moving in the proximal direction.
摘要翻译：本发明提供了一种输送装置，其包括流体盒保持器，壳体和包括中空活塞杆和驱动轴的活塞驱动机构。中空活塞杆具有与驱动轴的外螺纹配合的内螺纹，形成螺纹连接并相对于壳体沿近端方向轴向限制。驱动机构又通过单向棘轮连接到壳体，从而防止活塞杆沿近端方向移动。

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