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31. 发明申请

WO2015153456A1 METHOD AND APPARATUS FOR DISCRIMINATING TACHYCARDIA EVENTS IN A MEDICAL DEVICE 审中-公开
标题翻译：用于在医疗设备中鉴别TACHYCARDIA事件的方法和装置
公开(公告)号：WO2015153456A1
公开(公告)日：2015-10-08
申请号：PCT/US2015/023335
申请日：2015-03-30
申请人： MEDTRONIC, INC.
发明人： ZHANG, Xusheng , STADLER, Robert, W.
IPC分类号： A61N1/39 , A61B5/0452 , A61B5/0464 , A61B5/00
CPC分类号： A61N1/39 , A61B5/0452 , A61B5/0464 , A61B5/686 , A61N1/3925 , A61N1/3956
摘要： A method and medical device for detecting a cardiac event that includes sensing cardiac signals from a plurality of electrodes, the plurality of electrodes forming a first sensing vector and a second sensing vector, identifying the cardiac event as one of a shockable event and a non-shockable event in response to first processing of a first interval sensed along the first sensing vector during a predetermined sensing window and a second interval simultaneously sensed along the second sensing vector, performing second processing of the first interval and the second interval, different from the first processing, in response to the cardiac event being identified as a shockable event, and determining whether to delay identifying the cardiac event being shockable in response to the second processing of the first interval and the second interval.
摘要翻译：一种用于检测心脏事件的方法和医疗装置，其包括感测来自多个电极的心脏信号，所述多个电极形成第一感测向量和第二感测向量，将心脏事件识别为可震荡事件之一，响应于在预定感测窗口期间沿着第一感测向量感测的第一间隔的第一处理和沿着第二感测向量同时感测的第二间隔的第一处理的可触发事件，执行与第一间隔和第二间隔不同的第一处理响应于心脏事件被识别为可触发事件，以及响应于第一间隔和第二间隔的第二处理，确定是否延迟识别可震荡的心脏事件。

32. 发明申请

WO2018140343A1 DETECTION OF ELECTROMAGNETIC INTERFERENCE IN A CARDIAC ELECTRICAL SIGNAL BY AN IMPLANTABLE MEDICAL DEVICE 审中-公开
公开(公告)号：WO2018140343A1
公开(公告)日：2018-08-02
申请号：PCT/US2018/014648
申请日：2018-01-22
申请人： MEDTRONIC, INC.
发明人： ZHANG, Xusheng , GREENHUT, Saul E. , HEINKS, Michael W. , SOLHEIM, Paul R.
IPC分类号： A61N1/39 , A61N1/37
摘要： A medical device, such as an implantable cardioverter defibrillator (ICD), starts a timer set to a time interval in response to a cardiac electrical signal crossing a noise threshold amplitude and resets the timer to the time interval in response to each crossing of the noise threshold amplitude by the cardiac electrical signal that occurs prior to the time interval expiring. A control circuit of the medical device determines a parameter of the behavior of the timer and identifies a sensed cardiac event as an electromagnetic interference (EMI) event based on the parameter. The medical device may detect EMI in response to the EMI event and withhold a tachyarrhythmia detection or therapy in response to EMI detection.

33. 发明申请

WO2018022422A1 CARDIAC ELECTRICAL SIGNAL NOISE DETECTION FOR TACHYARRHYTHMIA EPISODE REJECTION 审中-公开
标题翻译：心律失常性心律失常的心电图信号噪声检测
公开(公告)号：WO2018022422A1
公开(公告)日：2018-02-01
申请号：PCT/US2017/043081
申请日：2017-07-20
申请人： MEDTRONIC, INC.
发明人： GREENHUT, Saul E. , CAO, Jian , ZHANG, Xusheng
IPC分类号： A61N1/02 , A61N1/39 , A61N1/365 , A61N1/37 , A61N1/05 , A61B5/042
摘要： A medical device, such as an extra-cardiovascular implantable cardioverter defibrillator (ICD), senses R-waves from a first cardiac electrical signal by a first sensing channel and stores a time segment of a second cardiac electrical signal acquired by a second sensing channel in response to each sensed R-wave. The medical device determines at least one noise parameter from a group of the stored time segments of the second cardiac electrical signal, detects noise based on the noise parameter, and withholds detection of a tachyarrhythmia episode in response to detecting the noise.
摘要翻译：诸如额外心血管植入式心脏复律除颤器（ICD）之类的医疗设备通过第一感测通道感测来自第一心脏电信号的R波并且存储第二心脏电信号的时间段信号，其响应于每个感测的R波而由第二感测通道采集。医疗设备从第二心电信号的一组存储的时间段中确定至少一个噪声参数，基于噪声参数检测噪声，并且响应于检测到噪声而阻止检测到快速性心律失常事件。

34. 发明申请

WO2016069292A1 APPARATUS FOR SELECTION AND USE OF VIRTUAL SENSING VECTORS 审中-公开
标题翻译：选择和使用虚拟感知矢量的装置
公开(公告)号：WO2016069292A1
公开(公告)日：2016-05-06
申请号：PCT/US2015/055925
申请日：2015-10-16
申请人： MEDTRONIC, INC.
发明人： GREENHUT, Saul E. , ZHANG, Xusheng , STADLER, Robert W.
IPC分类号： A61B5/04 , A61B5/0452 , A61N1/37 , A61N1/39 , A61B5/0456 , A61B5/0472 , A61B5/00
CPC分类号： A61B5/04011 , A61B5/0205 , A61B5/0245 , A61B5/04012 , A61B5/0422 , A61B5/0452 , A61B5/04525 , A61B5/0456 , A61B5/0472 , A61B5/4836 , A61B5/7275 , A61B5/7282 , A61N1/3702 , A61N1/3925 , A61N1/3956 , A61N1/3962 , A61N1/3987
摘要： A medical device is configured to receive at least two physical cardiac electrical signals from a patient's heart via electrodes defining at least two physical sensing vectors. The medical device determines a signal feature for each of a plurality of virtual sensing vectors extending at a plurality of angles relative to one of the at least two physical sensing vectors during a known cardiac rhythm, compares the determined signal features and establishes criteria for confirming a suspected condition in response to the comparing.
摘要翻译：医疗设备被配置为经由定义至少两个物理感测向量的电极从患者的心脏接收至少两个物理心脏电信号。医疗设备确定在已知心律期间相对于所述至少两个物理感测向量之一以多个角度延伸的多个虚拟感测向量中的每一个的信号特征，比较确定的信号特征并建立用于确认怀疑病情反应比较。

35. 发明申请

WO2016003557A1 APPARATUS FOR VERIFYING DISCRIMINATING OF TACHYCARDIA EVENTS IN A MEDICAL DEVICE HAVING DUAL SENSING VECTORS 审中-公开
标题翻译：用于在具有双感测矢量的医疗设备中鉴别TACHYCARDIA事件的装置
公开(公告)号：WO2016003557A1
公开(公告)日：2016-01-07
申请号：PCT/US2015/032809
申请日：2015-05-28
申请人： MEDTRONIC, INC.
发明人： ZHANG, Xusheng
IPC分类号： A61N1/39 , A61B5/046
CPC分类号： A61N1/3987 , A61B5/04011 , A61B5/04012 , A61B5/0422 , A61B5/04525 , A61B5/0456 , A61B5/046 , A61B5/0464 , A61B5/0468 , A61B5/686 , A61B5/7207 , A61B5/7221 , A61B5/7264 , A61B5/7282 , A61N1/3621 , A61N1/3627 , A61N1/368 , A61N1/37 , A61N1/3956
摘要： A medical device for detecting a cardiac event that includes sensing cardiac signals from a plurality of electrodes, sensing a plurality of beats in response to the sensed cardiac signals, identifying each beat of the plurality of beats as one of a normal beat and a not normal beat, determining at least one of whether a number of beats identified as a normal beat is greater than a normal beat threshold, whether an RR interval associated with the beats identified as being a normal beat is less than a threshold interval, and whether RR intervals associated with the beats identified as being normal beats are within an RR interval range, and identifying the cardiac event as being one of shockable and not shockable in response to the determining.
摘要翻译：一种用于检测心脏事件的医疗装置，其包括感测来自多个电极的心脏信号，响应于感测的心脏信号感测多个心跳，将多个搏动中的每个搏动识别为正常搏动和非正常搏动之一拍摄，确定被识别为正常拍子的数量是否大于正常拍子阈值中的至少一个，与被识别为正常拍子的节拍相关联的RR间隔是否小于阈值间隔，以及RR间隔与被识别为正常搏动的节拍相关联在RR间隔范围内，并且响应于确定将心脏事件识别为可震荡且不可震荡的。

36. 发明申请

WO2015164293A1 METHOD AND APPARATUS FOR SELECTING A SENSING VECTOR CONFIGURATION IN A MEDICAL DEVICE 审中-公开
标题翻译：用于在医疗设备中选择感测矢量配置的方法和装置
公开(公告)号：WO2015164293A1
公开(公告)日：2015-10-29
申请号：PCT/US2015/026743
申请日：2015-04-21
申请人： MEDTRONIC, INC.
发明人： GREENHUT, Saul E. , STADLER, Robert W. , ZHANG, Xusheng
IPC分类号： A61B5/00 , A61B5/0452 , A61B5/04 , A61B5/0456 , A61N1/362
CPC分类号： A61N1/3621 , A61B5/0031 , A61B5/0422 , A61B5/0456 , A61B5/046 , A61B5/0464 , A61B5/686 , A61B5/7203 , A61B5/7221 , A61B5/7264 , A61B2560/0468
摘要： A method and medical device for determining sensing vectors that includes sensing cardiac signals from a plurality of electrodes, the plurality of electrodes forming a plurality of sensing vectors, determining signal differences during a detection window in each of the plurality of sensing vectors, ranking sensing vectors of the plurality of sensing vectors in response to the determined signal differences, and selecting one or more sensing vectors of the plurality of sensing vectors in response to the determined rankings.
摘要翻译：一种用于确定感测向量的方法和医疗装置，其包括感测来自多个电极的心脏信号，所述多个电极形成多个感测矢量，在所述多个感测矢量中的每一个中检测窗口期间确定信号差异，排列感测向量响应于所确定的信号差，并且响应于所确定的等级选择所述多个感测向量中的一个或多个感测向量。

37. 发明申请

WO2015164168A1 IMPLANTABLE CARDIOVERTER-DEFIBRILLATOR (ICD) TACHYARRHYTHMIA DETECTION MODIFICATIONS RESPONSIVE TO DETECTED PACING 审中-公开
标题翻译：可植入式除虫剂（ICD）TACHYARRHYTHMIA检测对被检测的PACING的检测
公开(公告)号：WO2015164168A1
公开(公告)日：2015-10-29
申请号：PCT/US2015/026096
申请日：2015-04-16
申请人： MEDTRONIC, INC.
发明人： STADLER, Robert W. , ZHANG, Xusheng , SHARMA, Vinod , REINKE, James D. , SCHMID, Barbara J.
IPC分类号： A61B5/0402 , A61N1/39 , A61N1/375 , A61N1/362 , A61N1/372
CPC分类号： A61B5/0464 , A61B5/04017 , A61B5/686 , A61N1/3621 , A61N1/37264 , A61N1/37288 , A61N1/3756 , A61N1/3962 , A61N1/3987
摘要： An implantable medical device comprises a sensing module configured to obtain electrical signals from one or more electrodes and a control module configured to process the electrical signals from the sensing module in accordance with a tachyarrhythmia detection algorithm to monitor for a tachyarrhythmia. The control module detects initiation of a pacing train delivered by a second implantable medical device, determines a type of the detected pacing train, and modifies the tachyarrhythmia detection algorithm based on the type of the detected pacing train.
摘要翻译：可植入医疗装置包括被配置为从一个或多个电极获得电信号的感测模块和被配置为根据快速性心律失常检测算法来处理来自感测模块的电信号以控制快速性心律失常的控制模块。控制模块检测由第二可植入医疗装置递送的起搏训练的起始，确定检测到的起搏训练的类型，并且基于检测到的起搏训练的类型来修改快速心律失常检测算法。

38. 发明申请

WO2013152166A2 HEART-SOUNDS BASED ADAPTIVE CARDIAC RESYNCHRONIZATION THERAPY TIMING PARAMETER OPTIMIZATION SYSTEM 审中-公开
标题翻译：基于心脏的自适应心脏再生治疗时间参数优化系统
公开(公告)号：WO2013152166A2
公开(公告)日：2013-10-10
申请号：PCT/US2013/035233
申请日：2013-04-04
申请人： MEDTRONIC, INC.
发明人： ZHANG, Xusheng , DEGROOT, Paul J. , GILLBERG, Jeffrey M , MULLEN, Thomas J , SAMBELASHVILI, Aleksandre T
IPC分类号： A61N1/368
CPC分类号： A61N1/36585 , A61N1/3627 , A61N1/3682 , A61N1/3684
摘要： A medical device and associated method for controlling a cardiac pacing therapy sense a first cardiac signal including events corresponding to cardiac electrical events and a second cardiac signal including events corresponding to cardiac hemodynamic events. A processor is enabled to measure a cardiac conduction time interval using the first cardiac signal and control a signal generator to deliver a pacing therapy. A pacing control parameter is adjusted to a plurality of settings during the pacing therapy delivery. A hemodynamic parameter value is measured from the second cardiac signal during application of each of the control parameter settings. The processor identifies an optimal setting from the plurality of settings and solves for a patient-specific equation defining the pacing control parameter as a function of the cardiac conduction time interval.
摘要翻译：用于控制心脏起搏治疗的医疗装置和相关联的方法感测包括对应于心脏电气事件的事件的第一心脏信号和包括对应于心脏血流动力学事件的事件的第二心脏信号。处理器能够使用第一心脏信号测量心脏传导时间间隔，并控制信号发生器以递送起搏治疗。在起搏治疗递送期间，起搏控制参数被调整为多个设置。在应用每个控制参数设置期间，从第二心脏信号测量血液动力学参数值。处理器从多个设置中识别最佳设置，并且针对定义作为心脏传导时间间隔的函数的起搏控制参数的患者特定方程进行求解。

39. 发明申请

WO2013138108A1 HEART SOUND SENSING TO REDUCE INAPPROPRIATE TACHYARRHYTHMIA THERAPY 审中-公开
标题翻译：心脏感觉减少不明显的TACHYARRHYTHMIA治疗
公开(公告)号：WO2013138108A1
公开(公告)日：2013-09-19
申请号：PCT/US2013/029051
申请日：2013-03-05
申请人： MEDTRONIC, INC.
发明人： ZHANG, Xusheng , WHITMAN, Teresa A. , DEGROOT, Paul J. , BROWN, Mark L. , GILLBERG, Jeffrey M.
IPC分类号： A61B5/00 , A61B5/0464 , A61B5/0456 , A61B7/00
CPC分类号： A61B5/7221 , A61B5/0456 , A61B5/046 , A61B5/0464 , A61B5/686 , A61B5/6869 , A61B5/7264 , A61B5/7285 , A61B7/00 , A61N1/3621 , A61N1/36514 , G06F19/00
摘要： Techniques for reducing inappropriate tachyarrhythmia therapy and associated medical device systems are described. In some examples a processor is enabled to receive a cardiac electrical signal representative of electrical activity of a heart of a patient and provide an indication of cardiac electrical signal reliability. A heart sound analyzing module is enabled to receive the indication of cardiac electrical signal reliability and a heart sound signal representing sounds generated by the heart of the patient and generated by a heart sound sensor. The heart sound analyzing module selectively determines an ensemble averaged heart sound signal or detects a plurality of heart sounds from the heart sound signal in response to the indication of cardiac electrical signal reliability.
摘要翻译：描述了用于减少不适当的快速性心律失常治疗和相关的医疗装置系统的技术。在一些示例中，处理器能够接收表示患者心脏的电活动的心脏电信号，并提供心脏电信号可靠性的指示。心音分析模块能够接收心电信号可靠性的指示，以及表示由心脏声音传感器产生的由患者的心脏产生的声音的心音信号。心脏声音分析模块响应于心脏电信号可靠性的指示，选择性地确定整体平均心音信号或从心音信号检测多个心音。

40. 发明申请

WO2019118560A1 SUPRAVENTRICULAR TACHYARRHYTHMIA DISCRIMINATION 审中-公开
公开(公告)号：WO2019118560A1
公开(公告)日：2019-06-20
申请号：PCT/US2018/065131
申请日：2018-12-12
申请人： MEDTRONIC, INC.
发明人： ZHANG, Xusheng , CAO, Jian
IPC分类号： A61N1/362 , A61N1/365 , A61N1/37
CPC分类号： A61N1/3621 , A61B5/0456 , A61B5/0464 , A61N1/3624 , A61N1/36592 , A61N1/3704 , A61N1/39622
摘要： Techniques are described for discriminating SVT and, in particular, rapidly conducting AF. The techniques include detecting an onset of a fast rate of ventricular events sensed from a cardiac electrical signal and detecting a pause in the fast rate of ventricular sensed events. A threshold number of ventricular event intervals required to detect a ventricular tachyarrhythmia is detected with each of the threshold number of ventricular event intervals being less than a tachyarrhythmia detection interval. Detection of the ventricular tachyarrhythmia and an electrical stimulation therapy for treating the ventricular tachyarrhythmia are withheld in response to at least the pause being detected.

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