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    • 21. 发明申请
    • STIMULATION DEVICE
    • 起搏设备
    • WO1997015347A1
    • 1997-05-01
    • PCT/EP1996004673
    • 1996-10-26
    • WASKÖNIG, Wilhelm
    • A61N01/05
    • A61N1/0551A61N1/36017A61N1/36021
    • The invention concerns a stimulation device, in particular for stimulating vesicular nerve sheaths or for use in the para-medullary region. The device comprises a voltage source and first and second electrodes which are connected to the voltage source and can be brought into conductive contact via a body. A first electrode is a pointed section (14) of a cannula (12) which is to be brought into the body region to be stimulated and has an aperture for the injection of drugs such as anaesthetics. The second electrode is a conductive connection which is disposed externally on the cannula at a spacing from the first electrode.
    • 本发明特别适用于血管神经鞘或paramedulären区域包括的刺激涉及一种刺激装置,电压源和在所述导电性连接连接到其上的第一和第二在体可以带来电极,其中第一电极,的前端侧部分(14) 在区域被刺激将被引入主体套管(12)与用于注入药物如麻醉剂和所述第二电极中的开口被布置在插管导电连接在外侧,其在从第一电极的距离。
    • 22. 发明申请
    • MEDICAL ELECTRICAL LEAD HAVING TEMPORARILY RIGID FIXATION
    • 具有临时刚性固定的医用电线
    • WO1997007851A1
    • 1997-03-06
    • PCT/US1996013358
    • 1996-08-16
    • MEDTRONIC, INC.
    • MEDTRONIC, INC.GRANDJEAN, Pierre, A.
    • A61N01/05
    • A61N1/0573A61N1/05
    • A medical electrical lead having active fixation (40) which readily flexes within the cardiac tissue (18). In particular, the present invention is a medical electrical lead having fixation mechanism which is temporarily rigid. In a preferred embodiment of the invention, the medical electrical lead features a fixation helix (40) constructed from an absorbable material, such as mannitol. In an alternate embodiment of the present invention, a medical electrical lead is disclosed which features a fixation mechanism having a multi-layer construction. In that embodiment the fixation mechanism is fahioned of a first (42), rigid and absorbable, material and a second (41), readily pliable and nonabsorbable, material. Through such a construction the lead may be fixed in the tissue (18) such that over time the first material (42) is absorbed by the body and the second material (41) is left in position to flexibly fix the lead in place. In one embodiment the second material (41) is conductive and is used to achieve an electrical coupling to the body tissue.
    • 一种具有主动固定(40)的医用电线,其易于在心脏组织(18)内弯曲。 特别地,本发明是具有临时刚性的固定机构的医疗用电线。 在本发明的优选实施例中,医用电引线具有由可吸收材料(例如甘露糖醇)构成的固定螺旋(40)。 在本发明的替代实施例中,公开了一种具有多层结构的固定机构的医用电线。 在该实施例中,固定机构由第一(42),刚性和可吸收的材料和第二(41)容易柔软和不可吸收的材料制成。 通过这样的结构,引线可以被固定在组织(18)中,使得随着时间的推移,第一材料(42)被主体吸收并且第二材料(41)保持就位以将引线柔性地固定就位。 在一个实施例中,第二材料(41)是导电的并且用于实现与身体组织的电耦合。
    • 23. 发明申请
    • IMPLANTABLE ENDOCARDIAL LEAD WITH SELF-HEALING RETRACTABLE FIXATION APPARATUS
    • 具有自愈式可折叠固定装置的可植入内窥镜
    • WO1996019259A1
    • 1996-06-27
    • PCT/US1995016264
    • 1995-12-18
    • INTERMEDICS, INC.
    • INTERMEDICS, INC.SPEHR, Paul, R.FRANKOVICH, Mark, M.WHITE, Mark, A.
    • A61N01/05
    • A61N1/0573
    • An implantable endocardial lead (10) with a retractable helix (48). A specialized stylet (50) can be inserted into the lead (10) at the proximal end and passed through the lead to the distal end. Located at the distal end of the lead is a piston (44) supporting the helix (48). The piston is attached to a coiled trifilar conductor (22) and has an electrode (14) adjacent the helix. Immediately adjacent the piston proximally an additional first short coil of wire is interlocked between the wires of the trifilar conductor (22), providing a female thread within the conductor. The stylet has a second single strand short coil segment spot welded to the stylet adjacent a distal end therof. The stylet (50) is rotated to screw the second short coil segment on the stylet into the first short coil adjacent the piston.
    • 一种具有伸缩螺旋(48)的可植入心内膜引线(10)。 可以在近端将特殊的探针(50)插入引线(10)中,并通过导线穿过远端。 位于引线的远端的是支撑螺旋(48)的活塞(44)。 活塞附接到螺旋三点状导体(22)并且具有与螺旋相邻的电极(14)。 紧邻靠近活塞的附近的第一短线圈线连接在三相导体(22)的导线之间,在导体内提供阴螺纹。 探针具有第二个单股短线圈段点焊接到邻近远端底座的探针。 探针(50)被旋转以将探针上的第二短线圈段拧到与活塞相邻的第一短线圈中。
    • 24. 发明申请
    • CARDIAC PACEMAKER WITH UNIVERSAL COATING
    • CARDIAC PACEMAKER与通用涂料
    • WO1996009087A2
    • 1996-03-28
    • PCT/US1995011849
    • 1995-09-19
    • INTERMEDICS, INC.
    • INTERMEDICS, INC.GARCIA, JohnALT, EckhardSTOTTS, Lawrence, J.
    • A61N01/05
    • A61N1/05A61N1/375
    • A pulse generator for a cardiac pacemaker is adapted to be implanted beneath the skin and adjacent the musculus with either of its two sides facing the musculus and its other side facing outwardly of the patient's body, at the option of the implanting surgeon, according to the desired orientation of the receptacle of the header for connection of an electrode lead to the pulse generator, and at the same time avoiding the presence of spurious signals attributable to flexation of the adjacent musculus and twitching attributable to stimulation of the adjacent musculus during operation of the pulse generator when implanted. To that end, the entire surface of the case is coated with an electrically insulative, biocompatible film except along a portion of the edge of the case between its two major sides which is to serve as an anodal contact surface for stimulating and sensing cardiac activity of the patient.
    • 用于心脏起搏器的脉冲发生器适于植入在皮肤下方并且与肌肉相邻,其两侧中的任一侧面向肌肉,并且其另一侧面向患者身体的外侧,根据植入外科医生的选择,根据 用于将电极引线连接到脉冲发生器的头部的插座的期望定向,并且同时避免由于相邻肌肉的弯曲引起的寄生信号的存在以及归因于在操作期间相邻肌肉的刺激的抽搐 脉冲发生器植入时。 为此,壳体的整个表面涂覆有电绝缘的生物相容性膜,除了沿其壳体的两个主要侧边缘的一部分之外,其用作刺激和感测心脏活动的阳极接触表面 患者。
    • 26. 发明申请
    • LOCALLY FLEXIBLE DILATOR SHEATH
    • 本地灵活的脱水器
    • WO1995033513A1
    • 1995-12-14
    • PCT/US1995007146
    • 1995-06-05
    • COOK PACEMAKER CORPORATION
    • COOK PACEMAKER CORPORATIONGOODE, LouisLUI, Chun, Kee
    • A61N01/05
    • A61N1/057A61B17/221A61B17/320016A61B17/32053A61B17/320708A61B17/32075A61B17/3468A61B2017/00243A61B2017/00247A61B2017/00292A61B2018/00392A61N1/056A61N2001/0578
    • A locally flexible dilator sheath (10) for separating encapsulating tissue from an implanted cardiac electrical lead. The dilator sheath includes an elongated tubular member (11) of a rigid stainless steel material, which is sized for placement of the tubular member over a cardiac lead that is implanted in the vascular system of a patient. The distal end (13) of the rigid tubular member is beveled to ease the separation of extremely tough tissue that encapsulates an implanted cardiac lead. To ease insertion around curves in the vascular system of the patient, the elongated tubular member includes a relieved portion (14). The relieved portion includes a relief pattern (15) of apertures (16, 17, 19, 23) in the elongated tubular member. The relief apertures preferably include diametrically opposed slots (24, 25) that extend perpendicularly into the tubular member. Adjacent pairs (44, 45) of slots are circumferentially offset at 90 DEG angle (26) to add further lateral flexiblity to the relieved portion. A polyester shrink tube (41) surrounds the relief apertures to provide integrity to the tubular member should the tubular member fracture when separating encapsulating tissue from the implanted lead.
    • 一种局部柔性扩张器护套(10),用于从注入的心电引线分离包封组织。 扩张器护套包括刚性不锈钢材料的细长管状构件(11),其尺寸适于将管状构件放置在植入患者血管系统中的心脏引线上。 刚性管状构件的远端(13)被倾斜以便于分离封装植入心脏引线的极其坚韧的组织。 围绕患者的血管系统中的曲线放松,细长的管状构件包括缓解部分(14)。 释放部分包括细长管状构件中的孔(16,17,19,23)的浮雕图案(15)。 减压孔优选地包括垂直地延伸到管状构件中的直径相对的狭槽(24,25)。 槽的相邻对(44,45)在90°角(26°)周向偏移,以增加释放部分的横向柔度。 如果在将包封组织与植入的导线分离时管状构件断裂,则聚酯收缩管(41)围绕所述释放孔以提供对管状构件的完整性。
    • 27. 发明申请
    • METHOD OF MAKING AN INCONTINENCE ELECTRODE
    • 制造不连续电极的方法
    • WO1995029733A1
    • 1995-11-09
    • PCT/US1995005328
    • 1995-04-28
    • EMPI, INC
    • EMPI, INCMALEWICZ, Andrzej
    • A61N01/05
    • A61N1/0524A61N1/0512
    • A method of manufacturing an electrode (10) comprises molding a plurality of spaced conductive sections (20, 22, 24) which include a pin receptacle (42, 44, 46) for receiving a connector pin (P1, P2, P3) of a wire harness (16). A skeleton of conductive sections (20, 22, 24), connector pins (P1, P2, P3) and lead wires (L1, L2, L3) are placed in a mold which defines the electrode (10). A non-conductive polymer is molded to the skeleton to form an integral electrode (10) having an elongated body (12) of conductive sections (20, 22, 24) separated by non-conductive sections (26, 28). Multiple durometer polymers may be used to achieve desired levels of flexibility of the electrode (10).
    • 制造电极(10)的方法包括模制多个间隔开的导电部分(20,22,24),该导电部分包括一个销插座(42,44,46),用于接收一个连接器针脚(P1,P2,P3) 线束(16)。 将导电部分(20,22,24),连接器针脚(P1,P2,P3)和引线(L1,L2,L3)的骨架放置在限定电极(10)的模具中。 非导电聚合物被模制到骨架上以形成具有由非导电部分(26,28)分开的导电部分(20,22,24)的细长主体(12)的整体电极(10)。 可以使用多重硬度聚合物来实现电极(10)的期望水平的柔性。
    • 30. 发明申请
    • MEDICAL ELECTRICAL LEAD
    • 医用电线
    • WO1995024943A1
    • 1995-09-21
    • PCT/US1995003087
    • 1995-03-06
    • MEDTRONIC, INC.
    • MEDTRONIC, INC.BREYEN, Mark, D.ISTEPHANOUS, Naim, S.KRASKA, Robert, E.LESSAR, Joseph, F.MILLER, Jennifer, P.
    • A61N01/05
    • A61N1/056
    • A medical electrical lead of the type which includes an electrode at a distal end of the lead, a connector at a proximal end of the lead and an elongated electrical conductor extending between the electrode and the connector. The conductor is comprised of a wire wound in a coil configuration with the wire comprised of a super austenitic stainless steel having a composition of at least 22 % nickel and 2 % molybdenum. Material of such composition has been found to have suitable conductivity for use with implantable pulse generators and suitable fatigue strength when used in endocardial lead placement. Moreover, such material has been found to pass tests intended to detect metal ion oxidation (MIO) in polymeric materials.
    • 一种医用电引线,其包括在引线的远端处的电极,在引线的近端处的连接器和在电极和连接器之间延伸的细长电导体。 该导体由卷绕成线圈构造的线组成,线由超级奥氏体不锈钢构成,其具有至少22%的镍和2%的钼的组成。 已经发现,这种组合物的材料具有适合的导电性,用于可植入的脉冲发生器,并且当用于心内膜引导放置时具有合适的疲劳强度。 此外,已经发现这种材料通过用于检测聚合物材料中的金属离子氧化(MIO)的测试。