专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

21. 发明申请

WO2014145715A1 METABOLITES OF N-(4-{[6,7-BIS(METHYLOXY)QUINOLIN-4-YL]OXY}PHENYL)-N'-(4-FLUOROPHENYL) CYCLOPROPANE-1,1-DICARBOXAMIDE 审中-公开
标题翻译： N-（4 - {[6,7-双（甲氧基）喹啉-4-基]氧基]苯基）-N' - （4-氟苯基）环丙基-1,1-二氧杂环己烷的代谢物
公开(公告)号：WO2014145715A1
公开(公告)日：2014-09-18
申请号：PCT/US2014/030524
申请日：2014-03-17
申请人： EXELIXIS, INC.
发明人： AFTAB, Dana, T. , NAGANATHAN, Sriram , XU, Wei , LACY, Steven , NGUYEN, Linh
IPC分类号： C07D215/22 , C07C305/24 , C07C233/60 , A61K31/47 , A61P35/00
CPC分类号： C07D215/22 , C07C233/60 , C07C305/24 , C07C2601/02 , C07D215/60 , G01N33/487 , G01N2570/00
摘要： The invention relates to metabolites of cabozantinib (I) as well as uses thereof.
摘要翻译：本发明涉及卡泊沙坦（I）的代谢物及其用途。

22. 发明申请

WO2014145693A1 METABOLITES OF N-[3-FLUORO-4-({ 6-(METHYLOXY)-7-[(3-MORPHOLIN-4-YLPROPYL)OXY]QUINOLIN-4-YL}OXY)PHENYL]-N'-(4-FLUOROPHENYL)CYCLOPROPANE-1,1-DICARBOXAMIDE 审中-公开
标题翻译： N- [3-氟-4-（{6-（甲基）-7 - [（3-吗啉-4-基）丙氧基]喹啉-4-基}氧]苯基] -N' - （4- 氟苯基）环-1,1-二甲酰胺
公开(公告)号：WO2014145693A1
公开(公告)日：2014-09-18
申请号：PCT/US2014/030498
申请日：2014-03-17
申请人： EXELIXIS, INC.
发明人： AFTAB, Dana, T. , NAGANATHAN, Sriram , XU, Wei , LACY, Steven , NGUYEN, Linh
IPC分类号： C07D215/22 , C07C305/24 , C07C233/60 , A61K31/47 , A61P35/00
CPC分类号： C07D215/22 , C07C233/60 , C07C305/24 , C07C2601/02
摘要： The invention relates to metabolites of foretinib (I) as well as uses thereof.
摘要翻译：本发明涉及前列肽（I）的代谢物及其用途。

23. 发明申请

WO2006117077A1 ARYL DERIVATIVES OF CURCUMIN, DEMETHOXYCURCUMIN, BISDEMETHOXYCURCUMIN OR CURCUMINISOXAZOLIDE AND THEIR USE AS ANIMAL FEED ADDITIVES 审中-公开
标题翻译：曲霉素，去氧胆红素，双嘧斯库霉素或酪氨酸激酶的ARYL衍生物及其作为动物饲料添加剂的用途
公开(公告)号：WO2006117077A1
公开(公告)日：2006-11-09
申请号：PCT/EP2006/003603
申请日：2006-04-20
申请人： DSM IP ASSETS B.V. , NEUPERT, Werner , SEON, Aurelia , SIMOES-NUNES, Carlos , WEHRLI, Christof
发明人： NEUPERT, Werner , SEON, Aurelia , SIMOES-NUNES, Carlos , WEHRLI, Christof
IPC分类号： A23K1/16 , A23L1/30 , C07C69/017 , C07C69/24 , C07C69/40 , C07C69/68 , C07C69/704 , C07C69/86 , C07C49/255 , C07C69/52 , C07C229/08 , C07C229/16
CPC分类号： C07C69/30 , A23K20/10 , A23K20/111 , A23K50/30 , A23K50/75 , C07C69/017 , C07C69/40 , C07C69/587 , C07C69/68 , C07C69/88 , C07C229/08 , C07C229/12 , C07C233/47 , C07C271/54 , C07C305/24 , C07F5/022 , C07F5/04 , C07F9/12
摘要： The present invention relates to the use of acyl derivatives of curcumin, desmethoxy curcumin and bisdesmethoxy curcumin and of curcuminisoxazolide as components of animal feed or feed additives for the improvement of animal performance and the new acyl derivatives per se as well as the corresponding animal feed or feed additives containing them.
摘要翻译：本发明涉及姜黄素，去甲氧基姜黄素和双甲氧基姜黄素和姜黄素恶唑的酰基衍生物作为动物饲料或饲料添加剂的组分用于改善动物性能和新的酰基衍生物本身以及相应的动物饲料或饲料添加剂含有它们。

24. 发明申请

WO2004031123A1 HYDROXYPHENYLUNDECANE DERIVATIVES, A PROCESS FOR THEIR PRODUCTION AND THEIR USE 审中-公开
标题翻译：羟基苯基衍生物及其生产方法及其使用
公开(公告)号：WO2004031123A1
公开(公告)日：2004-04-15
申请号：PCT/EP2003/010372
申请日：2003-09-18
申请人： AVENTIS PHARMA DEUTSCHLAND GMBH
发明人： HOPMANN, Cordula , KNAUF, Martin , BRÖNSTRUP, Mark , MARKUS-ERB, Astrid , TOTI, Luigi
IPC分类号： C07C69/88
CPC分类号： C07C69/88 , C07C305/24 , C12P7/6436 , C12R1/645
摘要： The present invention relates to novel hydroxyphenyludecane derivatives of the formula (I), a method for the preparation of said compounds by cultivation of the fungus Cryphonectria parasitica, DSM 14453, and their use as pharmaceuticals, i.e. for the treatment of Alzheimer’s Disease, Parkinson’s Disease, Huntington’s Diseases, stroke, psychosis and/or depressions.
摘要翻译：本发明涉及式（I）的新型羟基苯基十二烷衍生物，通过培养真菌寄生真菌DSM 14453制备所述化合物的方法及其作为药物的用途，即用于治疗阿尔茨海默病，帕金森病，亨廷顿舞蹈病，中风，精神病和/或沮丧。

25. 发明申请

WO2002072020A2 NOVEL ANTI-ADHESIVE COMPOUNDS AND USES THEREOF 审中-公开
标题翻译：新型抗粘合剂及其用途
公开(公告)号：WO2002072020A2
公开(公告)日：2002-09-19
申请号：PCT/US2002/007426
申请日：2002-03-12
申请人： PHYCOGEN, INC. , ALBERTE, Randall, S. , SMITH, Robert, D.
发明人： ALBERTE, Randall, S. , SMITH, Robert, D.
IPC分类号： A61K
CPC分类号： C40B40/04 , C07C69/732 , C07C229/36 , C07C305/24 , C07C309/65 , C07C309/66 , C08K5/0008 , C40B40/14 , C40B50/14
摘要： Compounds which exhibit anti-adhesive properties are described. The compounds may be monomers or polymers. Methods for treating receptor mediated diseases are provided using compounds of the invention. Further methods are provided for crop protection, medical devices and anti-fouling.
摘要翻译：描述了具有抗粘附性的化合物。化合物可以是单体或聚合物。使用本发明的化合物提供治疗受体介导的疾病的方法。为作物保护，医疗设备和防污提供了其他方法。

26. 发明申请

WO01074762A2 GENERATION OF COMBINATORIAL SYNTHETIC LIBRARIES AND SCREENING FOR PROADHESINS AND NONADHESINS 审中-公开
标题翻译：组合合成文库的生成和片段和非离子表面活性剂的筛选
公开(公告)号：WO01074762A2
公开(公告)日：2001-10-11
申请号：PCT/US2001/010969
申请日：2001-04-03
IPC分类号： C07B61/00 , C07C305/24 , C07C309/46 , C07C309/65 , C07C309/66 , C07D207/12 , C07D211/22 , C07D303/48 , A01N41/02 , A01N43/02 , A01N43/36 , A01N43/40 , A01N43/60 , C07D207/08 , C07D303/46 , C07D395/08
CPC分类号： C07C309/46 , C07C305/24 , C07C309/65 , C07C309/66 , C07D207/12 , C07D211/22 , C07D303/48 , C40B40/00
摘要： One aspect of the present invention relates to compounds, comprising at least two moieties selected from the group consisting of aryl sulfonates and aryl sulfates. A second aspect of the present invention relates to combinatorial libraries of the aforementioned compounds. The present invention also relates to compositions comprising a compound of the present invention. A fourth aspect of the present invention relates to the use of a compound or composition of the present invention in a method for inhibiting bioadhesion to a surface. Another aspect of the present invention relates to the use of a compound or composition of the present invention in a method for enhancing bioadhesion to a surface.
摘要翻译：本发明的一个方面涉及包含至少两个选自芳基磺酸盐和芳基硫酸盐的部分的化合物。本发明的第二方面涉及上述化合物的组合文库。本发明还涉及包含本发明化合物的组合物。本发明的第四方面涉及本发明的化合物或组合物在抑制生物粘附到表面的方法中的用途。本发明的另一方面涉及本发明化合物或组合物在增强表面生物粘附的方法中的用途。

27. 发明申请

WO99011606A2 INHIBITORS OF PROTEIN TYROSINE PHOSPHATASE 审中-公开
标题翻译：酪氨酸磷酸酶蛋白抑制剂
公开(公告)号：WO99011606A2
公开(公告)日：1999-03-11
申请号：PCT/US1998/017327
申请日：1998-08-24
IPC分类号： C07D295/12 , A61K31/197 , A61K31/215 , A61K31/4453 , A61K31/495 , A61K31/5375 , A61K38/00 , A61P3/10 , A61P43/00 , C07C233/18 , C07C235/34 , C07C235/74 , C07C235/80 , C07C237/22 , C07C237/52 , C07C271/02 , C07C271/22 , C07C275/24 , C07C275/42 , C07C305/24 , C07C311/06 , C07C311/13 , C07C311/37 , C07C311/46 , C07C311/47 , C07C317/50 , C07C323/59 , C07D295/13 , C07D295/20 , C07D295/215 , C07D521/00 , C07K5/06 , C07K5/065 , C07K5/068 , C07K5/072 , C07K5/078 , C07C235/00
CPC分类号： C07D295/215 , A61K38/00 , C07C235/74 , C07C235/80 , C07C237/52 , C07C271/02 , C07C271/22 , C07C275/24 , C07C305/24 , C07C311/06 , C07C311/13 , C07C311/37 , C07C317/50 , C07C323/59 , C07C2601/02 , C07C2601/08 , C07C2601/14 , C07C2603/66 , C07C2603/70 , C07D231/12 , C07D233/56 , C07D249/08 , C07D295/13 , C07K5/06026 , C07K5/06034 , C07K5/0606 , C07K5/06078 , C07K5/06086 , C07K5/06104 , C07K5/06113 , C07K5/06156
摘要： The present invention comprises small molecular weight, non-peptidic inhibitors of formula (I) and (II) of Protein Tyrosine Phosphatase 1 (PTP1) which are useful for the treatment and/or prevention of Non-Insulin Dependent Diabetes Mellitus (NIDDM).
摘要翻译：本发明涉及非肽抑制剂，低分子量，对应于用于非胰岛素依赖性糖尿病的治疗和预防的式I和II，蛋白酪氨酸磷酸酶。

28. 发明申请

WO1982000639A1 PROCESS FOR THE SYNTHESIS OF PHENOXYALKANE DERIVATIVES 审中-公开
标题翻译：合成苯甲酸衍生物的方法
公开(公告)号：WO1982000639A1
公开(公告)日：1982-03-04
申请号：PCT/AU1981000101
申请日：1981-07-31
申请人： ICI AUSTRALIA LTD , WATSON K
发明人： ICI AUSTRALIA LTD
IPC分类号： C07C69/92
CPC分类号： C07C59/68 , C07C303/24 , C07C305/24
摘要： Process for the synthesis of a compound of formula I (FORMULA) wherein: U and V may be chosen from a range of substituents including hydrogen, halogen, alkyl and alkoxy; R s and R s may be chosen from a range of substituents including hydrogen and alkyl; n is 0, 1 or 2; and W may be chosen from a range of substituents including the group -//c-G which may be a free carboxylic acid or derivative thereof; the process comprising reacting a sulfate ester of formula II, wherein Q is a cation, with a compound of formula III, wherein L is a leaving group (FORMULA) and hydrolysing the sulfate ester formed. Preferably the sulfate ester of formula II is prepared by the oxidation of a phenol of formula IV with a persulfate.
摘要翻译：用于合成式I化合物的方法（配方）其中：U和V可以选自包括氢，卤素，烷基和烷氧基的取代基范围; R 1和R 2可以选自包括氢和烷基的取代基的范围; n为0,1或2; 并且W可以从包括可以是游离羧酸或其衍生物的基团-c-G的取代基的范围中选择; 该方法包括使式II的硫酸酯（其中Q是阳离子）与式III化合物反应，其中L是离去基团（式）并水解形成的硫酸酯。优选地，式II的硫酸酯通过用过硫酸盐氧化式IV的酚来制备。

29. 发明申请

WO2010046926A2 NOVEL STILBENE ANALOGS 审中-公开
标题翻译：新的STILBENE模拟
公开(公告)号：WO2010046926A2
公开(公告)日：2010-04-29
申请号：PCT/IN2009/000580
申请日：2009-10-15
申请人： APTUIT LAURUS PVT LTD , GOTTUMUKKALA, Venkata, Subbaraju , HINDUPUR, Rama, Mohan , MASNA, Mahesh
发明人： GOTTUMUKKALA, Venkata, Subbaraju , HINDUPUR, Rama, Mohan , MASNA, Mahesh
IPC分类号： C07C39/215 , C07C43/215 , C07C1/34
CPC分类号： C07C39/215 , C07C43/215 , C07C43/225 , C07C43/23 , C07C65/28 , C07C69/017 , C07C69/712 , C07C215/74 , C07C217/18 , C07C217/80 , C07C229/08 , C07C229/22 , C07C233/25 , C07C233/75 , C07C271/22 , C07C271/26 , C07C305/24 , C07C307/02 , C07C309/66 , C07C309/73 , C07C311/08 , C07C311/21 , C07D295/088 , C07D309/12
摘要： The present invention relates to Stilbene derivatives of the general formula I or a pharmaceutically acceptable salt thereof have properties such as high water solubility, bioavailability and effective as carcinostatics.
摘要翻译：本发明涉及通式I的二苯乙烯衍生物或其药学上可接受的盐具有诸如高水溶性，生物利用度和作为制癌剂的有效性质。

30. 发明申请

WO2009076618A2 GENERATION OF COMBINATORIAL SYNTHETIC LIBRARIES AND SCREENING FOR NOVEL PROADHESINS AND NONADHESINS 审中-公开
标题翻译：组合合成文库的生成和新方案和非缔约国的筛选
公开(公告)号：WO2009076618A2
公开(公告)日：2009-06-18
申请号：PCT/US2008086638
申请日：2008-12-12
申请人： CERNOFINA LLC , ALBERTE RANDALL S , SMITH ROBERT D
发明人： ALBERTE RANDALL S , SMITH ROBERT D
IPC分类号： C07C305/22
CPC分类号： C07C305/24 , C07C309/46 , C07C309/65 , C07C309/66 , C07D207/12 , C07D211/22 , C07D303/48 , C40B40/00
摘要： The present invention relates to, in part, novel sulfate and bisphenol compounds useful for the recognition, attachment and growth of unwanted biologies on natural and manmade surfaces. Another aspect of the invention relates to combinatorial libraries for producing the same. Another aspect of the invention relates to pharmaceutical formulations comprising the same.
摘要翻译：本发明部分地涉及用于在天然和人造表面上识别，附着和生长不需要的生物制剂的新型硫酸盐和双酚化合物。本发明的另一方面涉及用于生产该组合文库的组合文库。本发明的另一方面涉及包含该制剂的药物制剂。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式