专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

21. 发明申请

WO2008021921A3 MEDICAL IMPLANT SHEETS USEFUL FOR TISSUE REGENERATION 审中-公开
标题翻译：适用于组织再生的医用植入物
公开(公告)号：WO2008021921A3
公开(公告)日：2008-05-22
申请号：PCT/US2007075538
申请日：2007-08-09
申请人： WARSAW ORTHOPEDIC INC , MCKAY WILLIAM F
发明人： MCKAY WILLIAM F
IPC分类号： A61L27/10 , A61F2/28 , A61F2/30 , A61L27/12 , A61L27/24 , A61L27/42 , A61L27/58
CPC分类号： A61B17/58 , A61B17/06066 , A61B17/06166 , A61B17/80 , A61C8/0006 , A61F2/2846 , A61F2/30907 , A61F2/30965 , A61F2/32 , A61F2/34 , A61F2/36 , A61F2/367 , A61F2/4081 , A61F2002/2825 , A61F2002/2835 , A61F2002/2871 , A61F2002/2892 , A61F2002/2896 , A61F2002/30064 , A61F2002/30153 , A61F2002/30289 , A61F2002/30327 , A61F2002/30428 , A61F2002/30785 , A61F2002/30957 , A61F2220/0025 , A61F2230/0019 , A61F2230/0091 , A61F2250/0039 , A61F2310/00796 , A61F2310/0097 , A61F2310/00976 , A61F2310/00982 , A61L27/446 , A61L27/58
摘要： Described is a medical device in the form of a thin sheet having granules of a calcium-containing, osteoconductive material interconnected by a thin web of polymeric material. The device includes a first face and a second face, wherein at least the first face is populated with proturbances presenting exposed regions of the calcium-containing, osteoconductive material provided by underlying granules. Methods of making and using such devices are also described, as are methods and devices involving the use of very thin polymeric sheets conformed to bone-ingrowth surfaces of load-bearing orthopedic implants.
摘要翻译：描述的是一种薄片形式的医疗装置，其具有通过聚合物材料薄网互连的含钙，骨传导材料的颗粒。所述装置包括第一面和第二面，其中至少所述第一面具有呈现由下面的颗粒提供的含钙，骨传导性材料的暴露区域的保湿性。还描述了制造和使用这些装置的方法，以及涉及使用符合承重整形外科植入物的骨向内生长表面的非常薄的聚合物片材的方法和装置。

22. 发明申请

WO2007130848A3 COMPOSITIONS COMPRISING BIOMEMBRANE SEALING AGENT FOR TREATMENT OF NEURONAL INJURY, AND METHODS OF USE 审中-公开
标题翻译：包含用于治疗神经损伤的生物膜密封剂的组合物及其使用方法
公开(公告)号：WO2007130848A3
公开(公告)日：2008-01-24
申请号：PCT/US2007067580
申请日：2007-04-27
申请人： WARSAW ORTHOPEDIC INC , ROY JOSEE , MCKAY WILLIAM F , MARX JEFFERY C MD
发明人： ROY JOSEE , MCKAY WILLIAM F , MARX JEFFERY C MD
IPC分类号： A61K33/06 , A61K47/10
CPC分类号： A61K33/06 , A61K9/0019 , A61K31/56 , A61K31/65 , A61K31/765 , A61K47/10
摘要： The invention provides compositions, kits, and methods for treatment of neuronal injury. In one embodiment, the composition comprises a biomembrane sealing agent, such as PEG, and a bioactive agent, such as a magnesium compound. The biomembrane sealing agent and/or the bioactive agent may be delivered by a method selected from the group consisting of an intravenous administration, an intramuscular administration, an intrathecal administration, a subcutaneous administration, an epidural administration, a parenteral administration, a direct application onto or adjacent to a site of the pathological condition, and any combinations thereof. Alternatively, the biomembrane sealing agent and/or the bioactive agent may be delivered from a pump or an implant.
摘要翻译：本发明提供用于治疗神经元损伤的组合物，试剂盒和方法。在一个实施方案中，组合物包含生物膜密封剂，例如PEG，以及生物活性剂，例如镁化合物。生物膜密封剂和/或生物活性剂可以通过选自静脉内给药，肌内给药，鞘内给药，皮下给药，硬膜外给药，肠胃外给药，直接施用于或与病理状况的位点相邻，以及其任何组合。或者，生物膜密封剂和/或生物活性剂可以从泵或植入物递送。

23. 发明申请

WO2012170417A3 METHODS AND COMPOSITIONS TO ENHANCE BONE GROWTH COMPRISING A STATIN 审中-公开
标题翻译：增强骨骼生长的方法和组合
公开(公告)号：WO2012170417A3
公开(公告)日：2013-03-28
申请号：PCT/US2012040903
申请日：2012-06-05
申请人： WARSAW ORTHOPEDIC INC , LI PING , MARX JEFFREY C , MCKAY WILLIAM F
发明人： LI PING , MARX JEFFREY C , MCKAY WILLIAM F
IPC分类号： A61L27/14 , A61F2/28 , A61M35/00 , C08L101/16
CPC分类号： A61K31/366 , A61F2002/2839 , A61F2002/30677 , A61K31/22 , A61K31/40 , A61K31/405 , A61K31/44 , A61K31/47 , A61K31/505 , A61K33/42 , A61K47/22
摘要： Implantable medical devices and methods are provided that have one or more statins disposed therein. The medical devices may be implanted at near or in a bone defect to enhance bone growth. In some embodiments, the medical device provided allows for sustain release of the statin and facilitates bone formation and repair of the fracture site.
摘要翻译：提供了植入式医疗装置和方法，其中设置有一个或多个他汀类药物。医疗装置可以植入在骨缺损附近或骨缺损处以增强骨生长。在一些实施方案中，所提供的医疗装置允许持续释放他汀类并促进骨形成部位的骨形成和修复。

24. 发明申请

WO2011094322A3 NEEDLE GUIDE SYSTEM 审中-公开
标题翻译：指针系统
公开(公告)号：WO2011094322A3
公开(公告)日：2011-12-08
申请号：PCT/US2011022588
申请日：2011-01-26
申请人： WARSAW ORTHOPEDIC INC , MCKAY WILLIAM F
发明人： MCKAY WILLIAM F
IPC分类号： A61M5/32 , A61M5/42 , A61M5/46
CPC分类号： A61M5/46 , A61B17/3401 , A61B17/3403 , A61B2017/347
摘要： A needle guide system comprising a needle guide including at least one wall defining an internal cavity and an outside of the needle guide. A lock is connected to the needle guide. The lock is movable between a first and a second position. A needle is disposed in the internal cavity of the needle guide, the needle having a long axis and a tip. The needle is movable along the long axis with respect to the needle guide when the lock is in the first position and the needle is locked to the needle guide and the tip extends beyond the wall of the needle guide when the lock is in the second position. Visual indicia on the lock may indicate whether the lock is in the first or the second position.
摘要翻译：一种针引导系统，其包括针引导件，该引导件包括限定内腔的至少一个壁和针引导件的外侧。一个锁连接到针导向器。锁可在第一和第二位置之间移动。针设置在针导向件的内腔中，针具有长轴和尖端。当锁处于第一位置时，针可以相对于针引导件沿着长轴移动，并且当锁处于第二位置时针被锁定到针引导件并且尖端延伸超过针引导件的壁。锁上的可视标记可以指示锁是处于第一还是第二位置。

25. 发明申请

WO2011053672A3 ULTRASONIC DEVICES AND METHODS TO DIAGNOSE PAIN GENERATORS 审中-公开
标题翻译：超声设备和诊断疼痛发生器的方法
公开(公告)号：WO2011053672A3
公开(公告)日：2011-07-28
申请号：PCT/US2010054403
申请日：2010-10-28
申请人： WARSAW ORTHOPEDIC INC , MCKAY WILLIAM F
发明人： MCKAY WILLIAM F
IPC分类号： A61B8/12
CPC分类号： A61B1/3135 , A61B5/4824 , A61B8/4245 , A61B8/4455 , A61B17/3401 , A61B2017/0073
摘要： Ultrasonic devices and methods are provided that diagnose one or more pain generators. In some embodiments, the ultrasonic devices and methods are utilized to map one or more pain generators at or near the spine so that appropriate diagnostic and treatment methods can be performed.
摘要翻译：提供诊断一个或多个疼痛发生器的超声波设备和方法。在一些实施例中，利用超声波装置和方法在脊柱处或附近映射一个或多个疼痛发生器，以便可以执行适当的诊断和治疗方法。

26. 发明申请

WO2010102120A9 METHODS AND COMPOSITIONS TO DIAGNOSE PAIN 审中-公开
标题翻译：诊断疼痛的方法和组成
公开(公告)号：WO2010102120A9
公开(公告)日：2011-01-13
申请号：PCT/US2010026228
申请日：2010-03-04
申请人： WARSAW ORTHOPEDIC INC , MCKAY WILLIAM F
发明人： MCKAY WILLIAM F
IPC分类号： A61B10/00 , A61K31/365 , A61M5/00 , A61M37/00 , A61P23/00 , A61P31/00
CPC分类号： A61K9/0024 , A61B5/4824 , A61K47/10 , A61K47/12 , A61M5/14276 , A61M5/178

27. 发明申请

WO2009129000A3 RIGID BONE GRAFT SUBSTITUTE 审中-公开
公开(公告)号：WO2009129000A3
公开(公告)日：2010-12-09
申请号：PCT/US2009036801
申请日：2009-03-11
申请人： WARSAW ORTHOPEDIC INC , MCKAY WILLIAM F
发明人： MCKAY WILLIAM F
IPC分类号： A61L27/24 , A61F2/28 , A61L27/40 , A61L27/54 , A61L27/56
CPC分类号： A61L27/56 , A61F2/2803 , A61F2002/2817 , A61F2002/30062 , A61F2002/3092 , A61F2002/3096 , A61F2210/0004 , A61F2310/00293 , A61F2310/00365 , A61L27/40 , A61L27/54 , A61L2300/414 , A61L2430/02
摘要： A bone graft substitute includes a porous matrix at least partially covered by a reinforcing outer layer. The porous matrix may be a collagen-ceramic composite, and the reinforcing outer layer may be formed from highly cross-linked collagen. The implant may also include one or more reinforcement ribs, which may be made from calcium phosphate or dense collagen. In addition, the bone graft substitute preferably includes an effective amount of a bioactive agent, such as BMP-2, rhBMP-2, or functional fragments thereof. The bioactive agent is preferably disposed within the porous matrix.
摘要翻译：骨移植物替代物包括至少部分被增强外层覆盖的多孔基质。多孔基质可以是胶原 - 陶瓷复合物，并且增强外层可以由高度交联的胶原形成。植入物还可以包括一个或多个加强肋，其可由磷酸钙或致密胶原制成。此外，骨移植物替代物优选包含有效量的生物活性剂，例如BMP-2，rhBMP-2或其功能片段。生物活性剂优选设置在多孔基质内。

28. 发明申请

WO2010059378A2 DRUG DEPOT WITH ANCHOR 审中-公开
标题翻译：药房与锚点
公开(公告)号：WO2010059378A2
公开(公告)日：2010-05-27
申请号：PCT/US2009062591
申请日：2009-10-29
申请人： WARSAW ORTHOPEDIC INC , MCKAY WILLIAM F
发明人： MCKAY WILLIAM F
IPC分类号： A61M5/14 , A61M31/00 , A61M37/00
CPC分类号： A61M31/002 , A61K9/0024 , A61M37/0069
摘要： A drug depot implantable at or near a target tissue site beneath the skin of a patient is provided, the drug depot comprising a therapeutically effective amount of a drug; at least one line having a distal end and a proximal end, the proximal end of the line attached to the drug depot; an anchor attached to the distal end of the line and configured to limit movement of the drug depot at or near the target tissue site, wherein the drug depot is capable of releasing the therapeutically effective amount of the drug over a period of at least one day. In some embodiments, the drug depot provided can include an effective amount of at least analgesic and/or at least one anti-inflammatory agent at or near a target site, and can reduce, prevent or treat inflammation and/or pain.
摘要翻译：提供可植入患者皮肤下方的目标组织部位处或附近的药物长效制剂，所述长效制剂包含治疗有效量的药物; 至少一条具有远端和近端的管线，所述管线的近端连接到药物贮库; 附接到所述线的所述远端并配置成限制所述药物贮库在所述目标组织部位处或附近的移动的锚，所述药物贮库能够在至少一天的时间内释放所述治疗有效量的所述药物。在一些实施方案中，所提供的长效制剂可以包括在靶位点处或附近的有效量的至少止痛剂和/或至少一种抗炎剂，并且可以减少，预防或治疗炎症和/或疼痛。

29. 发明申请

WO2009120484A2 PHARMACEUTICAL GELS AND METHODS FOR DELIVERING THERAPEUTIC AGENTS TO A SITE BENEATH THE SKIN 审中-公开
标题翻译：药物凝胶和将治疗药物输送到皮肤上的方法
公开(公告)号：WO2009120484A2
公开(公告)日：2009-10-01
申请号：PCT/US2009036482
申请日：2009-03-09
申请人： WARSAW ORTHOPEDIC INC , MCKAY WILLIAM F , ZANELLA JOHN MYERS
发明人： MCKAY WILLIAM F , ZANELLA JOHN MYERS
IPC分类号： A61K9/06 , A61P23/02 , A61P25/00 , A61P29/00
CPC分类号： A61K47/10 , A61K9/0019 , A61K9/0024 , A61K9/06 , A61K9/14 , A61K9/50 , A61K31/573 , A61K38/1875 , A61K51/1213 , C07K16/241 , C07K2317/21
摘要： Pharmaceutical gels and methods for delivering a therapeutic agent to a target tissue site beneath the skin of a patient are provided, the gel being capable of adhering to the target tissue site and comprising one or more biodegradable depots containing an effective amount of the therapeutic agent. In various embodiments, the gel is sprayable and hardens after contacting the target tissue site.
摘要翻译：提供了用于将治疗剂递送至患者皮肤下方的靶组织部位的药物凝胶和方法，所述凝胶能够粘附于靶组织部位并且包含一个或多个含有有效量的治疗剂的可生物降解储库。在各种实施方案中，凝胶是可喷雾的并且在接触靶组织部位后硬化。

30. 发明申请

WO2008076671A4 A BIODEGRADABLE OSTEOGENIC POROUS BIOMEDICAL IMPLANT WITH IMPERMEABLE MEMBRANE 审中-公开
标题翻译：具有不可渗透膜的生物可降解造口多孔生物医学植入物
公开(公告)号：WO2008076671A4
公开(公告)日：2009-07-09
申请号：PCT/US2007086771
申请日：2007-12-07
申请人： WARSAW ORTHOPEDIC INC , MCKAY WILLIAM F
发明人： MCKAY WILLIAM F
IPC分类号： A61L24/00 , A61L27/44 , A61L27/46
CPC分类号： A61L24/0015 , A61C8/0006 , A61F2/28 , A61F2/2803 , A61F2/2846 , A61F2/44 , A61F2002/2817 , A61F2002/2825 , A61F2002/2853 , A61F2002/2892 , A61F2002/30062 , A61F2002/30153 , A61F2002/30677 , A61F2210/0004 , A61F2230/0019 , A61F2310/00179 , A61F2310/00293 , A61F2310/00365 , A61L24/0036 , A61L24/0042 , A61L24/02 , A61L24/046 , A61L24/102 , A61L27/12 , A61L27/18 , A61L27/24 , A61L27/54 , A61L27/56 , A61L27/58 , A61L2300/252 , A61L2300/402 , A61L2300/406 , A61L2300/41 , A61L2300/414 , A61L2300/62 , C08L67/04
摘要： A biomedical implant is disclosed with osteogenic factors and a solid impermeable membrane occluding a portion of its surface for the generation of new bone growth at the target site of the implant. The implant is porous, bioresorbable, and forms a three dimensional architectural scaffold for the formation of new bone tissue. The implant is formed with a polymer or collagen, bone morphogenetic protein and ceramic particles.
摘要翻译：公开了一种生物医学植入物，其具有成骨因子和实体不可渗透的膜，所述实体不可渗透的膜阻塞其表面的一部分以在植入物的靶部位处产生新骨生长。植入物是多孔的，可生物再吸收的，并且形成用于形成新骨组织的三维结构支架。植入物由聚合物或胶原蛋白，骨形态发生蛋白和陶瓷颗粒形成。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式