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21. 发明申请

WO2007101772A1 A DRUG MIXING DEVICE 审中-公开
标题翻译：药物混合装置
公开(公告)号：WO2007101772A1
公开(公告)日：2007-09-13
申请号：PCT/EP2007/051439
申请日：2007-02-14
申请人： NOVO NORDISK A/S , RADMER, Bo , MØLLER, Claus , KLOK, Louise, Charlotte , GLEJBØL, Kristian , LARSEN, Poul , NØSTED, Ulrik
发明人： RADMER, Bo , MØLLER, Claus , KLOK, Louise, Charlotte , GLEJBØL, Kristian , LARSEN, Poul , NØSTED, Ulrik
IPC分类号： A61J1/00
CPC分类号： A61J1/2089 , A61J1/201 , A61J1/2013 , A61J1/2017 , A61J1/2051 , A61J1/2065 , A61J1/2075 , A61J1/2082 , A61J1/2086 , A61J1/2096
摘要： A drug mixing device (1) for mixing a dry drug, such as a lyophilized drug, with a liquid, thereby forming a liquid drug. The device (1) comprises a reservoir (2) containing a liquid, a vial holder (3) for receiving a vial (4) containing a dry drug, means (5, 7) for establishing a 5 fluid connection between the reservoir (2) and a vial (4) positioned in the vial holder (3) , means (8, 18) for forcing the liquid from the reservoir (2) to a vial (4) positioned in the vial holder (3) , and means (24, 9) for equalizing a pressure in the vial (4) . Transferring liquid from the reservoir (2) to the vial (4) causes the dry drug to become reconstituted. At least the reservoir (2) , the vial holder (3) , the means (5, 7) for establishing a fluid connection and (10) the forcing means (8, 18) form an at least substantially integral device.
摘要翻译：一种药物混合装置（1），用于将干燥药物如冻干药物与液体混合，从而形成液体药物。装置（1）包括容纳液体的储存器（2），用于接收含有干药物的小瓶（4）的小瓶保持器（3），用于在储存器（2）之间建立5流体连接的装置（5,7））和定位在小瓶保持器（3）中的小瓶（4），用于将液体从储存器（2）强制到定位在小瓶保持器（3）中的小瓶（4）的装置（8,18）和装置 24），用于均衡小瓶（4）中的压力。将液体从储存器（2）转移到小瓶（4）导致干燥药物重新构成。至少储存器（2），小瓶保持器（3），用于建立流体连接的装置（5,7）和（10）迫使装置（8,18）形成至少基本一体的装置。

22. 发明申请

WO2006089958A1 PUMP ASSEMBLY WITH SAFETY VALVE 审中-公开
标题翻译：泵与组装安全阀
公开(公告)号：WO2006089958A1
公开(公告)日：2006-08-31
申请号：PCT/EP2006/060277
申请日：2006-02-24
申请人： NOVO NORDISK A/S , LARSEN, Bjørn, Gullak , HANSEN, Steffen , GLEJBØL, Kristian , MØLLER-JENSEN, Peter , TOFT, Tue , HVID, Niels , LARSEN, Preben
发明人： LARSEN, Bjørn, Gullak , HANSEN, Steffen , GLEJBØL, Kristian , MØLLER-JENSEN, Peter , TOFT, Tue , HVID, Niels , LARSEN, Preben
IPC分类号： A61M5/142
CPC分类号： A61M5/14216 , A61M5/1413 , A61M5/14248 , A61M39/24 , A61M2005/14252 , A61M2005/1426 , A61M2005/14264 , A61M2005/14268 , A61M2005/1581 , A61M2005/1585 , A61M2039/242 , A61M2039/2433
摘要： The invention provides a pump assembly comprising a suction pump and a safety valve arranged between the pump inlet and a fluid inlet for the assembly. The safety valve comprises an inlet valve and a moveable control member acting on the safety inlet valve, wherein the control member is operatable between an initial position in which the safety inlet valve is closed, and an activated position in which the safety inlet valve is open, and wherein the control member is moved from the initial to the activated position by means of suction action from the pump. By this arrangement the opening of the safety valve is positively controlled by the suction provided by the pump whereas the safety valve is closed during non-operation of the pump.
摘要翻译：本发明提供了一种泵组件，其包括抽吸泵和布置在泵入口和用于组件的流体入口之间的安全阀。安全阀包括作用在安全入口阀上的入口阀和可移动控制构件，其中控制构件可在安全入口阀关闭的初始位置和安全入口阀打开的启动位置之间操作，并且其中所述控制构件通过来自所述泵的抽吸动作从初始位置移动到所述启动位置。通过这种安排，安全阀的打开由泵提供的抽吸积极地控制，而在泵的非操作期间安全阀关闭。

23. 发明申请

WO2006015922A1 A METHOD OF FORMING A STERILISED SENSOR PACKAGE AND A STERILISED SENSOR PACKAGE 审中-公开
标题翻译：形成消毒传感器包装和灭菌传感器包装的方法
公开(公告)号：WO2006015922A1
公开(公告)日：2006-02-16
申请号：PCT/EP2005/053357
申请日：2005-07-13
申请人： NOVO NORDISK A/S , EILERSEN, Michael , BUCH-RASMUSSEN, Thomas , GLEJBØL, Kristian
发明人： EILERSEN, Michael , BUCH-RASMUSSEN, Thomas , GLEJBØL, Kristian
IPC分类号： A61B5/00
CPC分类号： A61B5/14865 , A61B5/076 , A61B5/14532 , A61B5/6849 , A61B2560/063 , A61B2562/125 , A61B2562/242 , A61L2/087 , A61N1/05 , A61N1/08 , A61N1/375
摘要： A sensor package is provided comprising an implantable sensor having an electrode area and an electric contact area, the package comprising a shielding packaging enclosing at least the electrode area of the sensor while exposing the electric contact area. The sensor package fascilitates handling of the implantable sensor and provides for the possibility of sterilising the electric contact area leaving the electrode area protected.
摘要翻译：提供了包括具有电极区域和电接触区域的可植入传感器的传感器封装，所述封装包括在暴露所述电接触区域的同时封闭所述传感器的电极区域的屏蔽封装。传感器组件可以处理植入式传感器的处理，并提供对电气接触区域进行灭菌的可能性，使电极区域受到保护。

24. 发明申请

WO2005058395A1 A DELIVERY DEVICE WITH A VIBRATING HOLLOW CONDUIT SUCH AS AN INJECTION NEEDLE AND A METHOD FOR AUTOMATICALLY IDENTIFYING WHETHER LIQUID IS PRESENT IN A HOLLOW CONDUIT 审中-公开
标题翻译：具有作为注射针的振动中空导管的输送装置和用于自动识别的方法，无论液体是否存在于中空导管
公开(公告)号：WO2005058395A1
公开(公告)日：2005-06-30
申请号：PCT/DK2004/000786
申请日：2004-11-12
申请人： NOVO NORDISK A/S , GLEJBØL, Kristian , SMEDEGAARD, Jørgen, K. , KALLESØE, Bjarne, Skovmose
发明人： GLEJBØL, Kristian , SMEDEGAARD, Jørgen, K. , KALLESØE, Bjarne, Skovmose
IPC分类号： A61M5/158
CPC分类号： A61M5/365 , A61M5/14566 , A61M5/158 , A61M5/3146 , A61M2005/1581 , A61M2005/3123 , A61M2005/3289 , A61M2005/341 , A61M2205/6018
摘要： The invention relates to a delivery device and a method which has the ability to automatically decide when an air shot has been performed. The method is based on the principle of moni-toring the change in an initial resonance frequency of an injection needle during the filling of the injection needle. When the change of the initial resonance frequency becomes as ex-pected, the injection needle is considered filled with liquid and the air shot is fulfilled. The ex-pected change can be that of reaching a predetermined value or that of reaching a stable and constant level of values indicating that the resonance frequency of the filled injection needle is reached. Depending on the criteria for the expected change, a system able to iden-tify if the needle is partly filled or if the needle is 100 % filled can be set up.
摘要翻译：本发明涉及一种能够自动决定何时进行空气喷射的输送装置和方法。该方法基于在注射针的填充期间监测注射针的初始共振频率的变化的原理。当初始共振频率的变化变得如此，注射针被认为充满液体并且满足空气射击。预测的变化可以是达到预定值或达到指示填充注射针的共振频率达到的稳定和恒定水平的值。根据预期变化的标准，可以设置能够确定针头是否部分填充或者针头是否填充100％的系统。

25. 发明申请

WO2009092807A1 DEVICE FOR INJECTING APPORTIONED DOSES OF LIQUID DRUG 审中-公开
标题翻译：注射液体药液的装置
公开(公告)号：WO2009092807A1
公开(公告)日：2009-07-30
申请号：PCT/EP2009/050797
申请日：2009-01-23
申请人： NOVO NORDISK A/S , RADMER, Bo , GLEJBØL, Kristian , TORRY-SMITH, Jonas , MARKUSSEN, Tom Hede , BOM, Lars Morten , ENGGAARD, Christian Peter , NIEMANN, Sara Juana , EBRO, Martin
发明人： RADMER, Bo , GLEJBØL, Kristian , TORRY-SMITH, Jonas , MARKUSSEN, Tom Hede , BOM, Lars Morten , ENGGAARD, Christian Peter , NIEMANN, Sara Juana , EBRO, Martin
IPC分类号： A61M5/315 , A61M5/32
CPC分类号： A61M5/315 , A61M5/2033 , A61M5/24 , A61M5/3129 , A61M5/31541 , A61M5/31548 , A61M5/31571 , A61M5/31593 , A61M2005/202 , A61M2005/2073 , A61M2005/2407 , A61M2205/581 , A61M2205/583
摘要： A mechanical injection device (1) for injecting apportioned doses of liquid drug. The injection device (1) comprises a dose setting means, an injection means, a removable cap (15) and a cap receiving part (9) adapted to abut or engage with the cap (15) when the cap (15) is mounted on the injection device (1). The dose setting means is operatively coupled to the cap receiving part (9) in such a manner that mounting and/or dismounting of the cap (15) on/from the injection device (1) causes the dose setting means to set a dose. Thereby a correct dose of drug is automatically set during a cap on/cap off cycle. Since such a cycle is normally performed between two subsequent injections, the number of steps required to be performed by the user is reduced.
摘要翻译：一种用于注射分配剂量的液体药物的机械注射装置（1）。注射装置（1）包括剂量设定装置，注射装置，可拆卸盖（15）和盖接纳部分（9），当帽（15）安装在其上时适于与帽（15）抵接或接合注射装置（1）。剂量设定装置可操作地联接到帽接收部分（9），使得帽子（15）在注射装置（1）上的安装和/或拆卸使剂量设定装置设定剂量。因此，在上限/关闭周期期间，自动设置正确剂量的药物。由于这样的循环通常在两次后续喷射之间进行，因此减少了由用户执行的步骤数。

26. 发明申请

WO2009024562A1 MEDICAL DEVICE WITH VALUE SENSOR 审中-公开
标题翻译：具有数值传感器的医疗设备
公开(公告)号：WO2009024562A1
公开(公告)日：2009-02-26
申请号：PCT/EP2008/060813
申请日：2008-08-18
申请人： NOVO NORDISK A/S , JENSEN, Peter, Lundholm , GLEJBØL, Kristian , KLITMOSE, Lars, Peter , BOUAIDAT, Salim
发明人： JENSEN, Peter, Lundholm , GLEJBØL, Kristian , KLITMOSE, Lars, Peter , BOUAIDAT, Salim
IPC分类号： A61M5/31 , A61M5/48
CPC分类号： A61M5/486 , A61M5/1452 , A61M5/16854 , A61M5/24 , A61M5/31511 , A61M5/365 , A61M2005/16863 , A61M2005/3125 , A61M2205/15 , A61M2205/332 , A61M2205/3324 , A61M2205/3331 , A61M2205/3368 , A61M2205/35 , A61M2205/3569 , A61M2205/3592 , A61M2205/6054 , A61M2205/8243 , G06F19/00 , G06F19/3468
摘要： A RFID comprising a value sensor such as a pressure sensor is integrated with a liquid drug container to enable wireless pressure or other drug relevant parameter value monitoring and code-matching of drug container to a medical delivery device.
摘要翻译：包括诸如压力传感器的值传感器的RFID与液体药物容器集成，以使药物容器的无线压力或其他药物相关参数值监测和代码匹配到医疗输送装置。

27. 发明申请

WO2006032652A1 REMOTE COMMANDER TO BE USED WITH A DRUG DELIVERY DEVICE 审中-公开
标题翻译：使用药物递送设备的远程命令
公开(公告)号：WO2006032652A1
公开(公告)日：2006-03-30
申请号：PCT/EP2005/054676
申请日：2005-09-20
申请人： NOVO NORDISK A/S , DAMGAARD-SØRENSEN, Camilla , GLEJBØL, Kristian
发明人： DAMGAARD-SØRENSEN, Camilla , GLEJBØL, Kristian
IPC分类号： G06F19/00
CPC分类号： G06F19/3456 , G06F19/00 , G06F19/3418 , G16H40/63
摘要： The invention relates to a remote commander adapted to be used in combination with a drug delivery device comprising drug expelling means and a delivery receiver. The remote commander comprises user input means allowing a user to input data, and a transmitter adapted for wirelessly transmitting data to the delivery receiver for controlling the expelling means. The user input means comprises a dose setting member which is moveable in a first direction to a selected set position representing a set dose of drug to be delivered, as well as moveable in a second direction to selectively adjust the set position and thereby the set dose of drug. The user input means further comprises an actuation member providing that data representing the set dose can be transmitted to the delivery device to thereby expel the set dose of drug.
摘要翻译：本发明涉及一种适于与包括药物排出装置和递送接收器的药物递送装置组合使用的遥控器。遥控器包括允许用户输入数据的用户输入装置，以及适于将数据无线传送到传送接收器以控制排出装置的发射机。用户输入装置包括剂量设定构件，其可以在第一方向上移动到所选择的设定位置，所述设定位置表示要传递的药物的设定剂量，并且可在第二方向上移动，以选择性地调整设定位置，从而设定剂量的药物。用户输入装置还包括致动构件，其提供表示设定剂量的数据可以传送到递送装置，从而排出药物的设定剂量。

28. 发明申请

WO2006018425A2 MULTIPHASE BIOCOMPATIBLE SEMI-PERMEABLE MEMBRANE FOR BIOSENSORS 审中-公开
标题翻译：用于生物传感器的多相生物相容性半透膜
公开(公告)号：WO2006018425A2
公开(公告)日：2006-02-23
申请号：PCT/EP2005/054000
申请日：2005-08-15
申请人： NOVO NORDISK A/S , ROSSMEISL, Charlotte C. , SABRA, Mads Christian , GERSTENBERG, Michael , GLEJBØL, Kristian , BUCH-RASMUSSEN, Thomas
发明人： ROSSMEISL, Charlotte C. , SABRA, Mads Christian , GERSTENBERG, Michael , GLEJBØL, Kristian , BUCH-RASMUSSEN, Thomas
IPC分类号： B01D69/14 , B01D71/54 , A61B5/00 , C12Q1/00
CPC分类号： C12Q1/002 , A61B5/1486 , A61B5/411 , B01D69/141 , B01D71/54 , B01D71/70
摘要： This invention relates to a novel two phase biocompatible semi-permeable mem- brane for biosensors and more particularly to a homogenous membrane for us- age in in-vivo sensing of glucose by an enzyme. The membrane comprises of a continuous hydrophilic phase of water swellable polyurethane having discrete particles of polydimethyl siloxane dispersed therein. Furthermore, a membrane having good properties for use as the outer membrane in a biosensor continuous determination of the blood glucose level in vivo, can be prepared by spraying of a polymer solution in a big number of spraying steps, for example, more than 20 steps.
摘要翻译：本发明涉及一种用于生物传感器的新型两相生物相容性半渗透膜，更具体地涉及用于利用酶在体内感测葡萄糖的均质膜。该膜包含水分散性聚氨酯的连续亲水相，其中分散有聚二甲基硅氧烷分散颗粒。此外，在生物传感器中用作外膜的良好特性的膜可以通过在大量喷雾步骤中喷雾聚合物溶液来进行连续测定，例如超过20个步骤

29. 发明申请

WO2004022139A1 MOUNTING PLATFORM FOR SKIN PIERCING MEDICAL DEVICES 审中-公开
标题翻译：皮肤刺激医疗器械的安装平台
公开(公告)号：WO2004022139A1
公开(公告)日：2004-03-18
申请号：PCT/DK2003/000558
申请日：2003-08-26
申请人： NOVO NORDISK A/S
发明人： GLEJBØL, Kristian
IPC分类号： A61M5/32
CPC分类号： A61M5/3287 , A61B5/150022 , A61B5/150389 , A61B5/150503 , A61B5/15074 , A61B5/15142
摘要： This invention relates to mounting platform for skin piercing medical devices comprising a flexible patch having a first and a second side, where the first side carries an adhesive by which the patch is adhered to the skin, and where the second side of the patch is provided with a rigid construction defining a trans-dermal zone and carrying needle insertion guides and interfaces for connection of inserted catheters and probes to external equipment, where some or all the surface facing the skin is prepared with one or more bio-chemically active agents. Herby, the mounting platform ensures that trans-dermal devices are inserted within a pre defined area of the skin and that the insertions are made to the optimal depth and under the optimal angles.
摘要翻译：本发明涉及用于皮肤穿刺医疗装置的安装平台，其包括具有第一和第二侧面的柔性贴片，其中第一侧承载粘合剂，通过该粘合剂将贴片粘附到皮肤上，并且其中提供贴片的第二面其具有限定透皮区域的刚性结构，并且携带用于将插入的导管和探针连接到外部设备的针插入引导件和界面，其中使用一种或多种生物化学活性剂制备面向皮肤的一些或全部表面。 Herby，安装平台确保透皮装置插入皮肤预定义的区域内，并将插入物制成最佳深度和最佳角度。

30. 发明申请

WO2012092931A1 AN UNBONDED FLEXIBLE PIPE 审中-公开
标题翻译：不粘弹性管
公开(公告)号：WO2012092931A1
公开(公告)日：2012-07-12
申请号：PCT/DK2012/050002
申请日：2012-01-03
申请人： NATIONAL OILWELL VARCO DENMARK I/S , KASSOW, Kristian , GLEJBØL, Kristian
发明人： KASSOW, Kristian , GLEJBØL, Kristian
IPC分类号： F16L11/08
CPC分类号： F16L11/20 , F16L11/083 , F16L11/12 , F16L11/22 , F16L33/01
摘要： The invention relates to an unbonded flexible pipe for sub sea transportation of fluids. The pipe has a length and comprises a tubular inner sealing sheath (2) defining a bore and an axis (8) of the pipe. In a pipe length section it comprises a second sealing sheath (9) surrounding the inner sealing sheath (2) and forming an annulus between the inner sealing sheath and the second sealing sheath. The annulus provides a primary maintaining passage along the length of the pipe length section with a first and a second end. The pipe comprises at least one secondary maintaining passage (5) along the length of the pipe with a first and a second end. The secondary maintaining passage is arranged with an axial distance which is larger than the axial distance of the inner sealing sheath (2). The first end of one of the primary and the secondary maintaining passages is arranged as an input end for a maintaining fluid and the first end of the other of the primary and the secondary maintaining passages is arranged as an outflow end for the maintaining fluid, and the primary and the secondary maintaining passages are in fluidic connection with each other at their second ends to provide a pathway for the maintaining fluid. The pathway for a maintaining fluid makes it possible in a simple and effective manner to keep the corrosion of elements - such as armouring elements in the annulus - relativly low, and accordingly the duration of the unbonded flexible pipe can thereby be increased.
摘要翻译：本发明涉及用于海底输送流体的无粘合柔性管。管道具有长度并且包括限定孔的管状内部密封护套（2）和管道的轴线（8）。在管道长度部分中，其包括围绕内部密封护套（2）的第二密封护套（9），并且在内部密封护套和第二密封护套之间形成环形空间。环形空间沿着管长度段的长度提供具有第一和第二端的初级保持通道。该管道包括沿管道长度的第一和第二端部的至少一个次级保持通道（5）。副保持通道的轴向距离大于内密封护套（2）的轴向距离。第一和第二维持通道中的一个的第一端被布置为用于维持流体的输入端，并且另一个主维护通道和辅助保持通道的第一端被布置为用于维持流体的流出端，以及初级和次级保持通道在其第二端处彼此流体连接以提供维持流体的通路。用于维持流体的路径使得以简单有效的方式保持元件的腐蚀（例如环形空间中的铠装元件）相对较低，从而可以增加未粘合的柔性管的持续时间。

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