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21. 发明申请

WO2009007970A1 SYSTEMS AND METHODS FOR GLYCEMIC CONTROL DURING PUMP DISCONNECTION 审中-公开
标题翻译：泵排放期间糖化控制的系统和方法
公开(公告)号：WO2009007970A1
公开(公告)日：2009-01-15
申请号：PCT/IL2008/000950
申请日：2008-07-10
申请人： MEDINGO LTD. , YODFAT, Ofer , SHAPIRA, Gali
发明人： YODFAT, Ofer , SHAPIRA, Gali
IPC分类号： A61M5/142 , A61M5/172
CPC分类号： A61M5/1723 , A61M5/14244 , A61M2005/14208 , A61M2230/201
摘要： Techniques and devices are described for allowing a diabetes patient to safely disconnect an insulin infusion system device for a time period. In one aspect, the techniques and devices can be implemented by receiving a maximum blood glucose amount, a minimum blood glucose amount, and a contemplated disconnection time; receiving a current blood glucose amount of the user; determining an expected increase in blood glucose of the user based on the contemplated disconnection time, an insulin sensitivity of the user and a contemplated basal insulin dose; validating the contemplated disconnection time based on at least one of the expected increase in blood glucose, the maximum blood glucose amount, and the minimum blood glucose amount; and, administering a therapeutic action to the user based on the validation of the contemplated disconnection time.
摘要翻译：描述了允许糖尿病患者在一段时间内安全地断开胰岛素输注系统装置的技术和装置。在一个方面，可以通过接收最大血糖值，最小血糖值和预期的断开时间来实现技术和装置; 接收用户的当前血糖值; 基于预期的断开时间，用户的胰岛素敏感性和预期的基础胰岛素剂量来确定用户的血糖预期增加; 基于预期的血糖升高，最大血糖值和最小血糖值中的至少一个来验证预期的断开时间; 以及基于所述预期的断开时间的验证来向所述用户施加治疗动作。

22. 发明申请

WO2009001349A1 TAILORED BASAL INSULIN DELIVERY SYSTEM 审中-公开
标题翻译：定制的基本胰岛素输送系统
公开(公告)号：WO2009001349A1
公开(公告)日：2008-12-31
申请号：PCT/IL2008/000863
申请日：2008-06-25
申请人： MEDINGO LTD. , YODFAT, Ofer , SHAPIRA, Gali , GESCHEIT, Iddo, M.
发明人： YODFAT, Ofer , SHAPIRA, Gali , GESCHEIT, Iddo, M.
IPC分类号： A61M5/172 , G06F19/00 , A61M5/142
CPC分类号： A61M5/14248 , A61M5/1723 , A61M2005/14208 , A61M2005/14268 , A61M2005/14296 , A61M2005/1726 , A61M2205/3569 , A61M2205/52 , A61M2230/201 , G06F19/00 , G06F19/3468
摘要： Dislosed is a system to deliver insulin to a user's body. The system include a dispensing unit to deliver the insulin to the body, and a control mechanism to control delivery of basal insulin according to a predetermined basal infusion pattern, the basal infusion pattern selected from a plurality of predetermined basal infusion patterns (102). In some embodiments, selection o the basal infusion pattern may be based on one or more personal characteristics of the user.
摘要翻译：灭绝是将胰岛素输送给用户身体的系统。该系统包括用于将胰岛素输送到身体的分配单元和控制机构，用于根据预定的基础灌注模式控制基础胰岛素的输送，所述基础灌注模式选自多个预定的基础灌注模式（102）。在一些实施例中，基础输注模式的选择可以基于用户的一个或多个个人特征。

23. 发明申请

WO2008114254A1 USER INTERFACE FOR SELECTING BOLUS DOSES IN A DRUG DELIVERY DEVICE 审中-公开
标题翻译：用于在药物递送装置中选择螺旋剂的用户界面
公开(公告)号：WO2008114254A1
公开(公告)日：2008-09-25
申请号：PCT/IL2008/000380
申请日：2008-03-19
申请人： MEDINGO LTD. , YODFAT, Ofer , SHAPIRA, Gali , GESCHEIT, Iddo M.
发明人： YODFAT, Ofer , SHAPIRA, Gali , GESCHEIT, Iddo M.
IPC分类号： A61M5/172 , G06F19/00 , A61M5/14 , A61M5/142
CPC分类号： A61M5/14248 , A61M5/1413 , A61M5/1723 , A61M2005/14208 , A61M2005/14268 , A61M2205/3569 , A61M2205/3592 , A61M2205/505 , A61M2205/52 , G06F19/00 , G06Q50/22
摘要： An apparatus and system for selecting a bolus dose of a drug in a drug delivery device is disclosed. A bolus dose is selected from a pre-determined schedule of bolus doses, wherein each dose corresponds to a range of a body analyte levels.
摘要翻译：公开了一种用于在药物递送装置中选择药物的推注剂量的装置和系统。推注剂量选自预先确定的推注剂量时间表，其中每个剂量对应于身体分析物水平的范围。

24. 发明申请

WO2008078319A1 FLUID DELIVERY WITH IN VIVO ELECTROCHEMICAL ANALYTE SENSING 审中-公开
标题翻译：流体电化学分析仪中的流体传感器
公开(公告)号：WO2008078319A1
公开(公告)日：2008-07-03
申请号：PCT/IL2007/001579
申请日：2007-12-20
申请人： MEDINGO LTD. , YODFAT, Ofer , IDDAN, Gavriel J. , KAIDAR, Ruthy , SHAPIRA, Gali
发明人： YODFAT, Ofer , IDDAN, Gavriel J. , KAIDAR, Ruthy , SHAPIRA, Gali
IPC分类号： A61B5/00
CPC分类号： A61B5/14532 , A61B5/14865 , A61B5/1495 , A61M5/14248 , A61M5/1723 , A61M2005/14268 , A61M2205/50 , A61M2230/201
摘要： One or more therapeutic fluids, such as for example insulin can be delivered to a body. In addition or alternatively, the concentrations of one or more analytes can be measured in vivo. A feedback process can be used to regulate levels of the one or more analytes based on the measurements via delivery of the one or more therapeutic fluids. Related systems, apparatus, methods, and/or articles are also described.
摘要翻译：一种或多种治疗性流体，例如胰岛素可被递送至身体。另外或替代地，可以在体内测量一种或多种分析物的浓度。基于通过递送一种或多种治疗性流体的测量，可以使用反馈过程来调节一种或多种分析物的水平。还描述了相关系统，装置，方法和/或制品。

25. 发明申请

WO2008038274A1 FLUID DELIVERY SYSTEM WITH ELECTROCHEMICAL SENSING OF ANALYTE CONCENTRATION LEVELS 审中-公开
标题翻译：具有分析浓度水平的电化学感测的流体输送系统
公开(公告)号：WO2008038274A1
公开(公告)日：2008-04-03
申请号：PCT/IL2007/001177
申请日：2007-09-25
申请人： MEDINGO LTD. , YODFAT, Ofer , IDDAN, Gavriel, J. , KAIDAR, Ruthy , SHAPIRA, Gali
发明人： YODFAT, Ofer , IDDAN, Gavriel, J. , KAIDAR, Ruthy , SHAPIRA, Gali
IPC分类号： A61B5/00
CPC分类号： A61M5/14248 , A61B5/14525 , A61B5/1468 , A61B5/1486 , A61B5/4839 , A61B5/6848 , A61M5/1723 , A61M2005/1726 , A61M2230/201
摘要： A system and a method for delivering fluid to and sensing analyte levels in the body of the patient are disclosed. The system includes a dispensing apparatus configured to infuse fluid into the body of the patient and a sensing apparatus configured to be in communication with the dispensing apparatus and further configured to detect a level of analyte concentration in the body of the patient upon diffusion of the analyte into the fluid to be dispensed by the dispensing apparatus.
摘要翻译：公开了一种用于将流体输送到患者体内并感测患者体内的分析物水平的系统和方法。该系统包括配置成将流体注入到患者体内的分配装置和被配置成与分配装置连通的感测装置，并且还被配置成在分析物扩散时检测患者体内的分析物浓度水平进入待由分配装置分配的流体。

26. 发明申请

WO2012019746A1 METHOD AND SYSTEM FOR IMPROVING GLYCEMIC CONTROL 审中-公开
标题翻译：改善糖化控制的方法和系统
公开(公告)号：WO2012019746A1
公开(公告)日：2012-02-16
申请号：PCT/EP2011/003962
申请日：2011-08-08
申请人： ROCHE DIAGNOSTICS GMBH , F. HOFFMANN-LA ROCHE AG , YODFAT, Ofer , SHAPIRA, Gali
发明人： YODFAT, Ofer , SHAPIRA, Gali
IPC分类号： A61B5/00 , A61B5/145 , G06F19/00
CPC分类号： G06F19/3456 , A61B5/0002 , A61B5/14532 , A61B5/4839 , A61B5/4848 , A61B5/486 , G06F19/00 , G06F19/3468 , G06F19/3475
摘要： There are disclosed systems and methods of estimating a nutritional parameter of a food intake, comprising the steps of obtaining input values indicative of a measured postprandial blood parameter value and a blood parameter value associated with a medication dose value; determining from at least said obtained input values an estimate of the nutritional parameter of the food, and generating an output indicative of the determined estimate. The output can be an image, an audio signal or a vibration signal. One or more images associated with the food intake can be displayed. The history of past determined estimates and a nutrition recommendation can be displayed. Contents of the images can be analyzed. The postpandrial blood parameter value can be measured by a continuous monitoring device, at different delays. The nutritional parameter can be a carbohydrates load value, or a glycemic index value or a fat load value for example.
摘要翻译：公开了一种估计食物摄取量的营养参数的系统和方法，包括以下步骤：获得指示测量的餐后血液参数值和与药物剂量值相关联的血液参数值的输入值; 从至少所述获得的输入值确定食物的营养参数的估计，以及生成指示所确定的估计的输出。输出可以是图像，音频信号或振动信号。可以显示与食物摄入相关联的一个或多个图像。可以显示过去确定的估计和营养建议的历史。可以分析图像的内容。可以通过连续监测装置测量不同延迟时间后的血浆参数值。营养参数可以是碳水化合物负荷值，或例如血糖指数值或脂肪负荷值。

27. 发明申请

WO2009002455A1 METHOD AND DEVICE FOR PREVENTING HYPOGLYCEMIA 审中-公开
标题翻译：用于预防高血压的方法和装置
公开(公告)号：WO2009002455A1
公开(公告)日：2008-12-31
申请号：PCT/US2008/007733
申请日：2008-06-20
申请人： MEDINGO HEADQUARTERS , YODFAT, Ofer , RAMCHANDANI, Neesha , SHAPIRA, Gali
发明人： YODFAT, Ofer , RAMCHANDANI, Neesha , SHAPIRA, Gali
IPC分类号： G06F19/00
CPC分类号： A61M5/1723 , A61M5/14248 , A61M2005/14208 , A61M2005/14268 , A61M2005/1726 , A61M2205/3569 , A61M2205/52 , A61M2230/201 , G06F19/00 , G06F19/3456 , G16H50/50
摘要： A device and a method are provided that can be used for prevention of hypoglycemia. The method for prevention of hypoglycemia comprises receiving a target blood glucose (TBG) level corresponding to a desired level of glucose in a patient's body during a fasting time period; receiving a bedtime blood glucose (BBG) level corresponding to the level of glucose in the patient's body substantially at the beginning of the fasting time period; receiving a first set of parameters corresponding to a medical state of the patient; providing the levels of the TBG, BBG and the medical state of the patent to a therapeutic "course of action determining means,- and, providing means for administering the therapeutic course of action to the patient.
摘要翻译：提供了可用于预防低血糖的装置和方法。用于预防低血糖症的方法包括在空腹时间段期间接收对应于患者体内所需水平的葡萄糖的目标血糖（TBG）水平; 在空腹时间段开始时接收与患者体内葡萄糖水平相对应的睡前血糖（BBG）水平; 接收对应于患者的医疗状态的第一组参数; 将TBG，BBG和专利的医疗状态的水平提供给治疗“行动决定手段”，并且提供用于向患者施用治疗疗程的方法。

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