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21. 发明申请

WO1994006788A1 A FUNGICIDAL COMPOUND 审中-公开
标题翻译：杀真菌剂
公开(公告)号：WO1994006788A1
公开(公告)日：1994-03-31
申请号：PCT/DK1993000293
申请日：1993-09-14
申请人： NOVO NORDISK A/S , BREINHOLT, Jens , NIELSEN, Ruby, Ione
发明人： NOVO NORDISK A/S
IPC分类号： C07D323/00
CPC分类号： C12P17/08 , A01N43/90 , A23K30/00 , A23L3/3499 , A23L3/3544 , B27K3/343 , B27K3/38 , C07D323/00 , C12R1/80
摘要： Compounds having general formula (I) or general formula (II). Compounds of formulae (I) or (II) have interesting antifungal activities and may, accordingly, be used as active ingredients in fungicidal compositions.
摘要翻译：具有通式（I）或通式（II）的化合物。式（I）或（II）的化合物具有有趣的抗真菌活性，因此可用作杀真菌组合物中的活性成分。

22. 发明申请

WO1994000443A1 FUNGICIDALLY ACTIVE COMPOUNDS 审中-公开
标题翻译：杀真菌活性化合物
公开(公告)号：WO1994000443A1
公开(公告)日：1994-01-06
申请号：PCT/DK1993000190
申请日：1993-06-02
申请人： NOVO NORDISK A/S , BREINHOLT, Jens , LANGE, Lene
发明人： NOVO NORDISK A/S
IPC分类号： C07D307/46
CPC分类号： C07D307/34 , A01N43/08 , A01N63/04 , C12P17/04 , C12R1/645 , Y10S435/911
摘要： Compounds having formula (3), wherein R is hydrogen, straight or branched alkyl with 1-10 carbon atoms, straight or branched alkenyl with 2-10 carbon atoms, straight or branched alkynyl with 2-10 carbon atoms, benzyl or aryl, optionally mono- or plurisubstituted with straight or branched alkyl with 1-10 carbon atoms, hydroxy, alkoxy, halogen, an amino or a nitro group; and when R is H salts thereof, or R is acyl (R = -COR ) wherein R is straight or branched alkyl with 1-10 carbon atoms, alkenyl with 2-10 carbon atoms, alkynyl with 2-10 carbon atoms, or aryl, optionally mono- or plurisubstituted with alkyl with 1-10 carbon atoms, hydroxy, alkoxy, halogen, an amino or a nitro group. Compounds of formula (3) have interesting antifungal activities and may, accordingly, be used as active ingredients in fungicidal compositions.
摘要翻译：具有式（3）的化合物，其中R 1是氢，具有1-10个碳原子的直链或支链烷基，具有2-10个碳原子的直链或支链烯基，具有2-10个碳原子的直链或支链炔基，苄基或芳基，任选被具有1-10个碳原子的直链或支链烷基，羟基，烷氧基，卤素，氨基或硝基单取代或多取代; 当R 1为其H盐时，或R 1为酰基（R 1 = -COR 2），其中R 2为具有1-10个碳原子的直链或支链烷基，具有2个 -10个碳原子的炔基，或具有1-10个碳原子的烷基，羟基，烷氧基，卤素，氨基或硝基单取代或多取代的芳基。式（3）的化合物具有有趣的抗真菌活性，因此可用作杀真菌组合物中的活性成分。

23. 发明申请

WO1993022444A1 FUNGICIDALLY ACTIVE COMPOUNDS 审中-公开
标题翻译：杀真菌活性化合物
公开(公告)号：WO1993022444A1
公开(公告)日：1993-11-11
申请号：PCT/DK1993000145
申请日：1993-04-30
申请人： NOVO NORDISK A/S , BREINHOLT, Jens , ROSENDAHL, Connie, Ninna , DEMUTH, Helle
发明人： NOVO NORDISK A/S
IPC分类号： C12P17/02
CPC分类号： C12R1/645 , A01N49/00 , A01N63/04 , C07D309/38 , C12P17/162
摘要： Compounds of formula (I), wherein R is hydrogen, straight or branched alkyl with 1 to 6 carbon atoms, such as methyl, straight or branched hydroxyalkyl with 1 to 6 carbon atoms, such as CH2OH, straight or branched alkylethers with 1 to 6 carbon atoms or optionally substituted aromatic ethers; each R independently are hydrogen, straight or branched alkyl with 1 to 6 carbon atoms, such as methyl, straight or branched hydroxyalkyl with 1 to 6 carbon atoms, such as CH2OH, straight or branched alkylethers with 1 to 6 carbon atoms, or optionally substituted aromatic ethers; and each R independently are hydrogen, hydroxy, methoxy, acetoxy, straight or branched alkylethers with 1 to 6 carbon atoms, or optionally substituted aromatic ethers; and wherein the chiral centres a, b, c, d, e, f, and g each independently may have the R or S configuration; except for the compound, wherein R is -CH2-OH, all of R are -CH3, and all of R are -OH (formula Ib); or agronomically acceptable salts or esters thereof have been found to have fungicidal activity. Furthermore processes for producing such compounds by cultivation of a species belonging to the genus Fusarium on suitable nutrient media are given. The invention also relates to fungicidal compositions comprising these compounds, either alone or in combination with known biocides or growth regulators, and the use of the compounds or compositions of the invention for controlling fungi.
摘要翻译：式（I）的化合物，其中R 1是氢，具有1至6个碳原子的直链或支链烷基，例如具有1至6个碳原子的甲基，直链或支链羟烷基，例如CH 2 OH，直链或支链烷基醚， 1至6个碳原子或任选取代的芳族醚; 每个R 2独立地是氢，具有1至6个碳原子的直链或支链烷基，例如甲基，具有1至6个碳原子的直链或支链羟烷基，例如CH 2 OH，具有1至6个碳原子的直链或支链烷基醚，或任选取代的芳族醚; 并且每个R 3独立地是氢，羟基，甲氧基，乙酰氧基，具有1至6个碳原子的直链或支链烷基醚或任选取代的芳族醚; 并且其中手性中心a，b，c，d，e，f和g各自独立地可以具有R或S构型; 除了其中R 1是-CH 2 -OH的化合物外，所有R 2都是-CH 3，并且所有的R 3都是-OH（式Ib）; 或其农艺学上可接受的盐或酯已被发现具有杀真菌活性。此外，给出了通过在合适的营养培养基上种植属于镰刀菌属的物种来生产这种化合物的方法。本发明还涉及包含这些化合物的杀真菌组合物，其单独或与已知的杀生物剂或生长调节剂组合，以及本发明化合物或组合物用于防治真菌的用途。

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