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21. 发明申请

WO2013106617A2 GENES CONFERRING TOLERANCE TO ETHANOL AND HIGH TEMPERATURES FOR YEASTS 审中-公开
标题翻译：基于对乙烯和乙烯的高温的承认
公开(公告)号：WO2013106617A2
公开(公告)日：2013-07-18
申请号：PCT/US2013021100
申请日：2013-01-11
申请人： ARCHER DANIELS MIDLAND CO
发明人： ABBAS CHARLES , SIBIRNY ANDRIY A , VORONOVSKY ANDRIY Y , ISHCHUK OLENA P
IPC分类号： C12P7/06
CPC分类号： C12P7/06 , C07K14/39 , C07K14/395 , C12N15/81 , C12N15/815 , C12Q1/6811 , Y02E50/17
摘要： Methods of identifying genes conferring ethanol tolerance in yeasts, genes that confer ethanol tolerance, and mutant strains used to identify such genes are described. A gene herein designated HpETT1 was isolated from the yeast Hansenula polymorpha. Expression of HpETT1 in an ethanol sensitive mutant H. polymorpha strain designated 7E complimented ethanol sensitivity of the mutant. When multiple copies of the HpETT1 were integrated into the genome and overexpressed, the transformed strain demonstrated approximately 10-fold greater resistance to ethanol and resistance to the protein misfolding agent AZC. Expression of HpETT1 also increased ethanol tolerance in Saccharomyces cerevisiae. HpEtt1 has 39% sequence identity to a previously identified protein from S. cerevisiae denoted MPE1, however, the MPE1 gene does not confer ethanol resistance to the 7E mutant. Another gene from the yeast Pichia stipites was identified that encodes an orthologue protein having 37% identity to HpETT1 herein designated PsETT1 and also confers ethanol resistance to the 7E mutant.
摘要翻译：描述赋予酵母中乙醇耐受性的基因，赋予乙醇耐性的基因和用于鉴定这些基因的突变菌株的方法。本文命名为HpETT1的基因从酵母多形汉逊酵母中分离。 HpETT1在乙醇敏感突变体多形汉逊酵母菌株中的表达命名为7E，突变体的乙醇敏感性。当HpETT1的多个拷贝整合到基因组中并过表达时，转化的菌株表现出对乙醇的抗性大约为10倍，并且对蛋白质错误折叠剂AZC具有抗性。 HpETT1的表达也增加了酿酒酵母中的乙醇耐受性。 HpEtt1与来自酿酒酵母的先前鉴定的蛋白质具有39％的序列同一性，表示MPE1，然而，MPE1基因不赋予7E突变体的乙醇抗性。鉴定了来自酵母毕赤酵母属的另一个基因，其编码与本文命名为PsETT1的HpETT1具有37％同一性的直向同源物蛋白，并且还赋予7E突变体的乙醇抗性。

22. 发明申请

WO2012068105A2 COMPOSITIONS AND USES THEREOF IN CONVERTING CONTAMINANTS 审中-公开
标题翻译：组合物及其在转化污染物中的用途
公开(公告)号：WO2012068105A2
公开(公告)日：2012-05-24
申请号：PCT/US2011060785
申请日：2011-11-15
申请人： ARCHER DANIELS MIDLAND CO , JRW BIOREMEDIATION LLC , BASEETH SHIREEN , SEBREE BRUCE , SMITH DONOVAN , ISENHOUR GWYN
发明人： BASEETH SHIREEN , SEBREE BRUCE , SMITH DONOVAN , ISENHOUR GWYN
IPC分类号： A62D3/34 , A62D101/22
CPC分类号： C02F1/70 , B09C1/002 , B09C1/08 , C02F1/444 , C02F1/705 , C02F3/28 , C02F3/348 , C02F2101/36 , C02F2103/06 , C02F2209/06 , C02F2305/04 , C02F2305/08 , Y02E50/343 , Y02W10/45
摘要： Compositions for converting contaminants or dispersing compounds are described. Systems and methods of using the compositions are also disclosed.
摘要翻译：描述了用于转化污染物或分散化合物的组合物。还公开了使用组合物的系统和方法。

23. 发明申请

WO2011159418A2 PROCESSES FOR DEODORIZING RENEWABLE-SOURCED GLYCOLS 审中-公开
标题翻译：用于清除可再生来源的甘油的方法
公开(公告)号：WO2011159418A2
公开(公告)日：2011-12-22
申请号：PCT/US2011036719
申请日：2011-05-17
申请人： ARCHER DANIELS MIDLAND CO , BLOOM PAUL D , MA CHICHENG
发明人： BLOOM PAUL D , MA CHICHENG
IPC分类号： C07C29/86 , C07B63/00 , C07C29/76 , C07C31/20
CPC分类号： C07B63/02 , C07C29/09 , C07C29/76 , C07C29/80 , C07C29/88 , C07C31/225
摘要： Processes are described for deodorizing a renewable source-based glycol product prepared from five and six-carbon sugars and sugar alcohols from biomass, including a distilled or otherwise purified glycol product meeting pharmaceutical grade purity requirements. In one embodiment, more acidic, higher odor profile materials are reacted with a weak base to form salts with a lower odor profile. In an alternate approach, odor-causing materials present in the renewable source-based glycol product are removed by liquid-liquid extraction.
摘要翻译：描述了将来自生物质的五种和六种碳糖和糖醇制备的可再生源的二醇产物除臭的方法，包括满足药物级纯度要求的蒸馏或其它纯化的二醇产物。在一个实施方案中，较酸性较高的气味分布材料与弱碱反应形成具有较低气味分布的盐。在替代方法中，通过液 - 液萃取除去存在于可再生源基二醇产物中的引起异味的物质。

24. 发明申请

WO2009137574A3 DEVELOPMENT OF STRAINS OF THE THERMOTOLERANT YEAST HANSENULA POLYMORPHA CAPABLE OF ALCOHOLIC FERMENTATION OF STARCH AND XYLAN BY EXPRESSION OF STARCH AND XYLAN DEGRADING ENZYMES 审中-公开
标题翻译：通过淀粉和XYLAN降解酶的表达可以发现热稳定性YEAST HANSENULA多糖的菌株能够发酵淀粉和XYLAN的醇溶性发酵
公开(公告)号：WO2009137574A3
公开(公告)日：2010-04-15
申请号：PCT/US2009042975
申请日：2009-05-06
申请人： ARCHER DANIELS MIDLAND CO , ABBAS CHARLES , SIBIRNY ANDRIY , VORONOVSKY ANDRIY Y
发明人： ABBAS CHARLES , SIBIRNY ANDRIY , VORONOVSKY ANDRIY Y
IPC分类号： C12N1/19 , C12N15/56 , C12P7/06 , C12R1/01
CPC分类号： C12N9/2428 , C12N9/2414 , C12N9/242 , C12P7/06 , C12Y302/01001 , C12Y302/01003 , C12Y302/01008 , C12Y302/01037 , C12Y401/01001 , Y02E50/17 , Y02P20/52
摘要： Genes SWA2 and GAMl from the yeast, Schwanniomyces occidentalis, encoding a- amylase and glucoamylase, respectively, were cloned and expressed in H. polymorpha. The expression was achieved by integration of the SWA2 and GAMl genes into the chromosome of H. polymorpha under operably linked to a strong constitutive promoter of the H. polymorpha - glyceraldehyde-3 -phosphate dehydrogenase gene (HpGAP. Resulting transformants acquired the ability to grow on a minimal medium containing soluble starch as a sole carbon source and can produce Ethanol at high-temperature fermentation from starch up to 10 g/L. A XYN2 gene encoding endoxylanase was obtained from the fungus Trichoderma resee, and a xlnD gene coding for ß-xylosidase was obtained from the fungus Aspergillus niger. Co-expression of these genes was also achieved by integration into the H. polymorpha chromosome under control of the HpGAP promoter. The resulting transformants were capable of growth on a minimal medium supplemented with birchwood xylan as a sole carbon source. Successful expression of xylanolytic enzymes resulted in a recipient strain capable of fermentation of birchwood xylan to ethanol at 48° C. Further with co expression of the forgoing genes in a H. polymorpha strain that overexpresses a pyruvate decarboxylase gene further improved ethanol production.
摘要翻译：来自酵母的基因SWA2和GAM1分别编码α-淀粉酶和葡糖淀粉酶，分别在多形汉逊酵母中表达。通过与多形汉逊酵母 - 甘油醛-3-磷酸脱氢酶基因（HpGAP）的强组成型启动子可操作地连接，将SWA2和GAM1基因整合到多形汉逊酵母的染色体中来实现该表达。所得到的转化体获得了生长能力在含有可溶性淀粉作为唯一碳源的基本培养基上，可以从淀粉高温发酵至10g / L生产乙醇，从真菌木霉菌获得编码内切木聚糖酶的XYN2基因，编码ß的xlnD基因这些基因的共表达也通过在HpGAP启动子控制下融合到多形汉逊酵母染色体中而得到，所得转化体能够在补充有桦木木聚糖的基本培养基上生长单独的碳源成功表达木聚糖酶导致能够发酵桦木木聚糖的受体菌株到48℃的乙醇。此外，在多克隆多因子菌株中共表达过去基因，其过表达丙酮酸脱羧酶基因进一步改善了乙醇生产。

25. 发明申请

WO2009076627A3 CONVERSION OF CARBOHYDRATES TO HYDROXY-METHYLFURFURAL (HMF) AND DERIVATIVES 审中-公开
标题翻译：碳氢化合物转化成羟基甲基纤维素（HMF）和衍生物
公开(公告)号：WO2009076627A3
公开(公告)日：2009-10-15
申请号：PCT/US2008086659
申请日：2008-12-12
申请人： ARCHER DANIELS MIDLAND CO , SANBORN ALEXANDRA , HOWARD STEPHEN
发明人： SANBORN ALEXANDRA , HOWARD STEPHEN
IPC分类号： C07D307/50 , C07D307/54
CPC分类号： C07D307/50 , C07D307/44 , C07D307/48 , C07D307/54 , C07D307/68
摘要： A method of producing substantially pure HMF, HMF esters and other derivatives from a carbohydrate source by contacting the carbohydrate source with a solid phase catalyst. A carbohydrate starting material is heated in a solvent in a column and continuously flowed through a solid phase catalyst in the presence of an organic acid, or heated with the organic acid and a solid catalyst in solution to form a HMF ester. Heating without organic acid forms HMF. The resulting product is purified by filtration to remove the unreacted starting materials and catalyst. The HMF ester or a mixture of HMF and HMF ester may then be oxidized to 2,5- furandicarboxylic acid (FDCA) by combining the HMF ester with an organic acid, cobalt acetate, manganese acetate and sodium bromide under pressure. Alternatively, the HMF ester may be reduced to form a furan or tetrahydrofuran diol.
摘要翻译：通过使碳水化合物源与固相催化剂接触，从碳水化合物源生产基本上纯的HMF，HMF酯和其它衍生物的方法。将碳水化合物原料在柱中的溶剂中加热，并在有机酸存在下连续流过固相催化剂，或者用有机酸和固体催化剂在溶液中加热形成HMF酯。无有机酸加热形成HMF。所得产物通过过滤纯化以除去未反应的起始原料和催化剂。然后通过在压力下将HMF酯与有机酸，乙酸钴，乙酸锰和溴化钠混合，将HMF酯或HMF和HMF酯的混合物氧化成2,5-呋喃二羧酸（FDCA）。或者，HMF酯可以还原形成呋喃或四氢呋喃二醇。

26. 发明申请

WO2008137123A2 COMPOSITIONS AND USES THEREOF IN BIOREMEDIATION 审中-公开
标题翻译：组合物及其在生物多样性中的应用
公开(公告)号：WO2008137123A2
公开(公告)日：2008-11-13
申请号：PCT/US2008005753
申请日：2008-05-05
申请人： ARCHER DANIELS MIDLAND CO , BASEETH SHIREEN , BLOOM PAUL , SEBREE BRUCE , SMITH DONOVAN
发明人： BASEETH SHIREEN , BLOOM PAUL , SEBREE BRUCE , SMITH DONOVAN
CPC分类号： B09C1/00 , B09B3/00 , B09C1/002 , B09C1/08 , B09C1/10 , C02F3/34 , C02F2101/36 , C02F2101/363 , C02F2103/001 , C02F2103/06 , C02F2305/06 , Y02W10/45
摘要： Compositions for bioremediation are described. Systems and methods of using the compositions are also disclosed.
摘要翻译：描述了用于生物修复的组合物。还公开了使用组合物的系统和方法。

27. 发明申请

WO2008098210A2 FOOD PRODUCTS CONTAINING TUBER AND LEGUME PRODUCTS AND PROCESSES FOR PRODUCING THE SAME 审中-公开
标题翻译：含有管和产品的食品及其制造方法
公开(公告)号：WO2008098210A2
公开(公告)日：2008-08-14
申请号：PCT/US2008053486
申请日：2008-02-08
申请人： ARCHER DANIELS MIDLAND CO , WERSTAK CHALES E , LEDBETTER KAETI R , BINDER THOMAS P
发明人： WERSTAK CHALES E , LEDBETTER KAETI R , BINDER THOMAS P
CPC分类号： A23L33/16 , A23L11/01 , A23L11/05 , A23L19/12 , A23L19/13 , A23L19/15 , A23L19/19 , A23L33/15 , A23V2002/00 , A23V2300/04
摘要： Edible compositions comprising legume products and tuber products are disclosed. In certain examples, the compositions can comprise bean powder combined with instant mashed potatoes. Such compositions can have excellent taste and improved nutrition. Methods of manufacture and preparation of the legume and tuber products are also disclosed.
摘要翻译：公开了包含豆类产品和块茎产品的食用组合物。在某些实例中，组合物可以包含与即时土豆泥组合的豆粉。这样的组合物可以具有优异的味道和改善的营养。还公开了豆类和块茎产品的制造和制备方法。

28. 发明申请

WO2008057220A3 APPLICATIONS OF BIOBASED GLYCOL COMPOSITIONS 审中-公开
标题翻译：生物活性甘醇组合物的应用
公开(公告)号：WO2008057220A3
公开(公告)日：2008-08-14
申请号：PCT/US2007022531
申请日：2007-10-24
申请人： ARCHER DANIELS MIDLAND CO , BINDER THOMAS PAUL , BLOOM PAUL D , POPPE GEORGE B
发明人： BINDER THOMAS PAUL , BLOOM PAUL D , POPPE GEORGE B
IPC分类号： C07C29/60 , C07C31/20 , C09K3/18 , C09K5/06
CPC分类号： C09K5/10 , C07C29/60 , C07C67/08 , C09D5/024 , C09K3/18 , C12C11/02 , C07C31/202 , C07C31/207 , C07C31/04 , C07C31/225 , C07C31/205 , C07C31/10 , C07C69/716 , C07C69/68 , C07C69/704
摘要： A biobased replacement for propylene glycol and ethylene glycol derived from petrochemical sources is presented. The product mixture from the hydrogenolysis of certain polyols from biobased renewable resources may replace propylene glycol and ethylene glycol products from petrochemical sources. Applications and methods of the biobased hydrogenolysis product mixture are disclosed. The compositions and methods provide a feedstock for industrial use which has a 13 C/ 12 C isotope ratio characteristic of bioderived material.
摘要翻译：介绍了从石化来源获得的丙二醇和乙二醇的生物基替代品。来自生物基可再生资源的某些多元醇的氢解的产物混合物可以取代来自石化来源的丙二醇和乙二醇产物。公开了生物基氢解产物混合物的应用和方法。该组合物和方法提供了一种工业用原料，其具有生物衍生材料的特征。

29. 发明申请

WO2008063485A3 PROCESS FOR HYDROGEN GAS PRODUCTION FROM CARBOHYDRATE FEEDSTOCKS 审中-公开
标题翻译：从碳氢化合物原料生产氢气的方法
公开(公告)号：WO2008063485A3
公开(公告)日：2008-08-07
申请号：PCT/US2007023798
申请日：2007-11-15
申请人： ARCHER DANIELS MIDLAND CO , ABBAS CHARLES A , BINDER THOMAS P , SOLHEIM LEIF P , MATLOCK MARK
发明人： ABBAS CHARLES A , BINDER THOMAS P , SOLHEIM LEIF P , MATLOCK MARK
IPC分类号： C10L5/00
CPC分类号： C01B3/323 , C01B2203/0233 , C01B2203/1052 , C01B2203/1211 , C10J3/78 , C10J2300/0916 , C10J2300/0979 , C10L3/08 , Y02P20/145
摘要： A method for producing hydrogen from a plant source is disclosed. The method includes contacting a crude carbohydrate material obtained from the plant source with water and a catalyst at a temperature and pressure sufficient to decompose at least a portion of the crude carbohydrate material to form a vapor mixture of gases including hydrogen, and separating hydrogen from other gases present in the vapor mixture.
摘要翻译：公开了一种从植物来源产生氢的方法。该方法包括将得自植物来源的粗制碳水化合物材料与水和催化剂接触，温度和压力足以分解至少一部分粗碳水化合物材料以形成包括氢气在内的气体的蒸汽混合物，并将氢气与其他物质分离存在于蒸汽混合物中的气体。

30. 发明申请

WO2007126594A3 LIGHT-COLOR PLANT OILS AND RELATED METHODS 审中-公开
标题翻译：浅色植物油及相关方法
公开(公告)号：WO2007126594A3
公开(公告)日：2008-05-08
申请号：PCT/US2007006503
申请日：2007-03-14
申请人： ARCHER DANIELS MIDLAND CO , LEE INMOK , PFALZGRAF LISA MARIE
发明人： LEE INMOK , PFALZGRAF LISA MARIE
IPC分类号： A23D9/04 , C11B3/00 , C11B3/04
CPC分类号： C11B3/10 , A23D9/00 , C11B3/006 , C11B3/06
摘要： Methods of producing light-color, color stable plant oils are presented. Cationic ion exchange resins have been found to be effective in removing color bodies from plant oils to produce a light-color, color stable plant oil. The methods may be applied to plant oils, including corn oil. Color stable corn oils having a light color are also presented. A composition comprising a corn oil having a colour value of less than 1.0 red on the lovibond scale is claimed.
摘要翻译：提出了生产浅色，颜色稳定的植物油的方法。已经发现阳离子离子交换树脂有效地从植物油中除去着色体以产生浅色，稳定的植物油。该方法可以应用于植物油，包括玉米油。还提供了具有浅色的颜色稳定的玉米油。要求保护含有颜色值小于1.0红色的玉米油的组合物。

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