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21. 发明申请

WO2002072237A1 AIR LAID/WET LAID GAS FILTRATION MEDIA 审中-公开
标题翻译：空气/湿气气体过滤介质
公开(公告)号：WO2002072237A1
公开(公告)日：2002-09-19
申请号：PCT/US2001/043088
申请日：2001-11-13
申请人： LYDALL, INC.
发明人： DOHERTY, Joseph, P.
IPC分类号： B01D46/52
CPC分类号： B01D46/10 , B01D39/1615 , B01D39/163 , B01D39/201 , B01D39/2013 , B01D46/0032 , B01D46/0035 , B01D46/521 , B01D2275/00 , B03C3/155 , B03C3/28 , Y10S55/05 , Y10S55/39
摘要： A pleatable high efficiency non-woven, gas filtration media is provided. The media has an electrically charged air laid fibrous layer with a thickness between about 2 and 35 mils, and a wet laid fibrous layer having a thickness of between about 5 and about 35 mils. The combined layers have, (a) a thickness of between about 10 and about 50 mils, (b) a stiffness of between about 200 and about 3500 mgs, (c) a Fraizer of between about 10 and about 400 CFM, and (d) an α of at least 15.
摘要翻译：提供了一种可打褶的高效无纺布气体过滤介质。介质具有厚度在约2和35密耳之间的带电空气铺设的纤维层，以及厚度在约5至约35密耳之间的湿法成网纤维层。组合层具有（a）约10至约50密耳之间的厚度，（b）约200至约3500mg之间的刚度，（c）约10至约400CFM的Fraizer和（d ）至少为15的α。

22. 发明申请

WO2002009845A3 UNITARY MULTI-COMPONENT FILTER MEDIA 审中-公开
公开(公告)号：WO2002009845A3
公开(公告)日：2002-02-07
申请号：PCT/US2001/023627
申请日：2001-07-27
申请人： LYDALL, INC.
发明人： POSA, James, M. , MCCARTHY, Michael, P.
IPC分类号： B01D39/16
摘要： A high efficiency particulate air (HEPA) filter made from a layer of electrostatically-charged thermoplastic fiber scrim that is point-bonded to a layer of glass fiber batting to form a composite layer defining an area, wherein the point-bonding is distributed over substantially all of the area of the composite layer and the bond points constitute approximately 1 % to approximately 6 % of the total surface area of the welded filter material, and wherein the composite layer is substantially uncompressed. Also, a process for forming the filter by providing an ultrasonic rotary drum having a large number of projections from the surface of the drum, passing a layer of electrostatically-charged thermoplastic fiber scrim resting on top of a layer of glass fiber batting over said drum in such a manner that said projections do not substantially penetrate into the subassembly, and passing the subassembly resting on top of the projections under an ultrasonic horn emitting high frequency sound waves into the subassembly to form point-bonds in the vicinity of the projections.

23. 发明申请

WO2022245361A1 MAGNETIC SUSPENSION DEVICE 审中-公开
公开(公告)号：WO2022245361A1
公开(公告)日：2022-11-24
申请号：PCT/US2021/033455
申请日：2021-05-20
申请人： SRI LLC
发明人： JENG, Phong-Ning , HSIEH, Edward Kuan Hsiung , YANG, Chun-Hsien
IPC分类号： H02N15/00 , G09B27/02 , G09B27/08 , A47G1/17
摘要： A magnetic suspension device is provided, including: a base, including at least two first magnetic action units arranged in interval and corresponding to each other; and a suspension member, including at least two second magnetic action units, the at least two second magnetic action units magnetically interact with the at least two first magnetic action units so that the suspension member is suspended between the at least two first magnetic units.

24. 发明申请

WO2021158216A1 MULTI-TUBE ADAPTER 审中-公开
公开(公告)号：WO2021158216A1
公开(公告)日：2021-08-12
申请号：PCT/US2020/016830
申请日：2020-02-05
申请人： LIU, Yi-Ching , TSAI, Hsin-Hua , CHANG, Chia-Fang
发明人： LIU, Yi-Ching , TSAI, Hsin-Hua
IPC分类号： A61M16/04 , A61J15/00 , A61M25/00 , A61M39/00
摘要： The invention discloses a multi-tube body adapter which is connected to a plurality of outer tubes for application to a digestive system and a respiratory system of a human body. The multi-tube body adapter includes a housing to form an accommodating space of the multi-chamber. The plurality of chambers is not in communication with each other. One end of the plurality of chambers respectively provides a connection port and the other end of the plurality of chambers is commonly connected to an extension having a plurality of openings. By connecting with the chamber, the connection port and the opening, a supply path for separately providing the supply path of the respiratory system and the digestive system can be formed.

25. 发明申请

WO2019164658A1 TILE SPACER 审中-公开
公开(公告)号：WO2019164658A1
公开(公告)日：2019-08-29
申请号：PCT/US2019/016377
申请日：2019-02-01
申请人： BYER, Ronald Lee
发明人： BYER, Ronald Lee
IPC分类号： E04F21/22 , E04F21/18 , E04F13/14 , E01C5/00 , E04F21/00 , E04F13/08 , E04F13/02
摘要： A tile spacer includes a head and a base having a top surface and a beveled edge that bevels from the top surface. The head is provided on the base and projects in a projection direction perpendicular to the top surface of the base. The tile space may also include at least one opening formed on the top surface of the base. The opening of the base may partially or fully extend through the base in a direction parallel to the projection direction of the head.

26. 发明申请

WO2016109541A1 METHOD FOR TREATING INFLUENZA A VIRUS INFECTION 审中-公开
标题翻译：用于治疗流感病毒感染的方法
公开(公告)号：WO2016109541A1
公开(公告)日：2016-07-07
申请号：PCT/US2015/067870
申请日：2015-12-29
申请人： ACADEMIA SINICA , LIANG, Chi-Ming
发明人： HSIEH, Shie-Liang , CHANG, Yung-Chi , HUANG, Ming-Ting
IPC分类号： A61K38/00
CPC分类号： A61K38/177 , C07K14/70578 , C07K2319/30
摘要： Disclosed herein is a method of treating influenza A virus (IAV) infection by a fusion protein. According to some embodiments of the present disclosure, the fusion protein comprises a HBD peptide and a IgG1 Fc region. According to other embodiments of the present disclosure, the fusion protein comprises a DcR3 protein and a IgG1 Fc region. The present fusion protein is found to possess inhibitory effects on IAV-induced secretion of the inflammatory cytokine, and IAV-induced infiltration of inflammatory cell into the lung tissue. Accordingly, the fusion protein is useful for developing a medicament for the treatment or prophylaxis of IAV infection and/or ameliorating pulmonary injury caused by excessive inflammation associated with IAV infection in a subject.
摘要翻译：本文公开了一种通过融合蛋白治疗甲型流感病毒（IAV）感染的方法。根据本公开的一些实施方案，融合蛋白包含HBD肽和IgG1 Fc区。根据本公开的其它实施方案，融合蛋白包含DcR3蛋白和IgG1 Fc区。发现本发现的融合蛋白具有对IAV诱导的炎症细胞因子分泌的抑制作用，并且IAV诱导的炎性细胞浸润到肺组织中。因此，融合蛋白可用于开发用于治疗或预防IAV感染和/或改善由受试者中与IAV感染相关的过度炎症引起的肺损伤的药物。

27. 发明申请

WO2016093823A1 ANTIBODIES AND METHOD FOR DETERMINING DELETIONS IN HBV PRE-S2 REGION 审中-公开
标题翻译：用于确定HBV PRE-S2区域中的删除的抗体和方法
公开(公告)号：WO2016093823A1
公开(公告)日：2016-06-16
申请号：PCT/US2014/069551
申请日：2014-12-10
申请人： NATIONAL HEALTH RESEARCH INSTITUTES , WANG, Lu-Hai
发明人： HUANG, Wenya , SU, Ih-Jen , LEE, Yun-Ping
IPC分类号： A61K39/29
CPC分类号： C07K16/082 , G01N33/543 , G01N33/56983 , G01N2333/02
摘要： A HBS-specific antibody, a LHBS-specific antibody, a WT LHBS-specific antibody, an immunoassay kit comprising the antibodies, and a method of detecting pre-S2 deletion mutant LHBS using the immunoassay kit are disclosed herein. The method comprises incubating a biological sample with a first antibody to captured HBS proteins; detecting the LHBS and WT LHBS bound to the immobilized first antibody, respectively; and calculating the amount of the pre-S2 deletion mutant LHBS protein by subtracting the amount of the WT LHBS protein from that of the LHBS protein. Advantageously, by the method described herein, the amount of the pre-S2 deletion mutant LHBS, a potential high-risk marker for HCC incidence in chronic HBV carriers and recurrence in HCC patients after hepatectomy surgery, in a biological sample may be easily calculated without mutual influence between the WT and pre-S mutant LHBS while reducing the labor-intensive process for cloning each gene product before analysis.
摘要翻译：本文公开了HBS特异性抗体，LHBS特异性抗体，WT LHBS特异性抗体，包含抗体的免疫测定试剂盒和使用免疫测定试剂盒检测pre-S2缺失突变体LHBS的方法。该方法包括将生物样品与捕获的HBS蛋白质的第一抗体孵育; 分别检测与固定的第一抗体结合的LHBS和WT LHBS; 并通过从LHBS蛋白的那些减去WT LHBS蛋白质的量来计算前S2缺失突变体LHBS蛋白质的量。有利地，通过本文所述的方法，可以容易地计算生物样品中pre-S2缺失突变体LHBS的量，即慢性HBV携带者中HCC发生率的潜在高危标志物和肝切除手术后肝细胞癌患者的复发，而没有 WT和前S突变体LHBS之间的相互影响，同时减少分析前克隆每种基因产物的劳动密集型过程。

28. 发明申请

WO2014127232A2 METHODS FOR MAINTAINING POPULATION OF THERAPEUTIC CELLS IN TREATMENT SITE OF SUBJECT IN NEED OF CELL THERAPY 审中-公开
标题翻译：维持治疗细胞治疗细胞人群在细胞治疗需要中的应用方法
公开(公告)号：WO2014127232A2
公开(公告)日：2014-08-21
申请号：PCT/US2014/016477
申请日：2014-02-14
申请人： DCB-USA LLC , NATIONAL CHENG KUNG UNIVERSITY
发明人： HSIEH, Patrick Ching-Ho , LAI, Chia-Yun
IPC分类号： A61K35/12
CPC分类号： A61K35/545 , A61K31/728 , A61K35/12 , A61K35/28 , A61K35/32 , A61K35/34 , A61K35/35 , A61K35/36 , A61K35/50 , A61K35/51 , A61K2300/00
摘要： Disclosed herein are methods for maintaining a population of therapeutic cells administered to a treatment site in a subject in need of cell therapy for a period of time. The methods include administering a therapeutically-effective amount of therapeutic cells and an effective amount of a biodegradable material to the treatment site. The biodegradable material includes a hyaluronan compound and has an in vivo degradation profile similar to that of a hyaluronic acid having a molecular weight of 20 kDa to 2,000 kDa.
摘要翻译：本文公开了用于维持在需要细胞治疗的受试者中施用于治疗部位一段时间的治疗细胞群的方法。所述方法包括向治疗部位施用治疗有效量的治疗细胞和有效量的生物可降解材料。可生物降解材料包括透明质酸化合物，并具有类似于分子量为20kDa至2,000kDa的透明质酸的体内降解特征。

29. 发明申请

WO2005009160A2 SHOE WITH DRAWER 审中-公开
标题翻译：带抽屉的鞋子
公开(公告)号：WO2005009160A2
公开(公告)日：2005-02-03
申请号：PCT/US2004/023080
申请日：2004-07-19
申请人： KIDSATIONAL, INC. , RUFF, Stephen, M.
发明人： RUFF, Stephen, M.
IPC分类号： A43B
CPC分类号： A43B13/14 , A43B3/0031
摘要： An article of footwear includes a sole portion; a second portion above the sole portion, the second portion including a compartment therein; and a drawer which is receivable within the compartment of the second portion and elastically attached to the article of footwear. The second portion is preferably a heel portion of the article of footwear, and the drawer is preferably engaged with the article of footwear by an elastic thread. The drawer may have an interior portion which is divided into a plurality of compartments.
摘要翻译：鞋类物品包括鞋底部分; 所述鞋底部分上方的第二部分，所述第二部分中包括隔室; 以及可容纳在第二部分的隔室内并弹性地附接到鞋类物品的抽屉。第二部分优选为鞋类物品的鞋跟部分，并且抽屉优选通过弹性线与鞋类物品接合。抽屉可具有被分成多个隔间的内部部分。

30. 发明申请

WO2003013278A1 IMPROVEMENTS IN PASTEURIZED EGGS 审中-公开
标题翻译：化妆品中的改良剂
公开(公告)号：WO2003013278A1
公开(公告)日：2003-02-20
申请号：PCT/US2002/005771
申请日：2002-02-28
申请人： DAVIDSON, L. John , WAGNER, Myron A.
发明人： DAVIDSON, L. John , WAGNER, Myron A.
IPC分类号： A23L1/32
CPC分类号： A23B5/12 , A23B5/0052 , A23B5/10 , A23B5/14 , A23B5/18 , A23L15/00 , A23L15/30
摘要： There is provided a process for pasteurizing in shell chicken eggs (2) carried in stacks (1) by placing the eggs in a heated fluid bath (4) having a temperature of between about 128 to 145 degrees F., allowing the eggs to dwell in the heated fluid bath until there is a log reduction of at least 4.6 of any Salmonella bacteria within the eggs, removing the eggs from the heated liquid bath and into a gaseous atmosphere (26), and contacting the eggs with an antibacterial fluid (28) containing an antibacterial agent. Preferably, the eggs are thereafter contacted with a sealant such as wax. In the gaseous atmosphere the eggs further pasteurize to at least a 5 logs reduction of the bacteria by way of residual heat in the eggs. During cooling in the gaseous atmosphere, the eggs suck the antibacterial fluid into the eggs between the inside of the shells and the membranes and provide antibacterial barriers in the eggs.
摘要翻译：提供了一种通过将蛋放置在温度在约128至145华氏度的加热流体浴（4）中的层叠（1）中携带的壳鸡蛋（2）中进行巴氏消毒的方法，允许蛋停留在加热的液体浴中，直到鸡蛋内任何沙门氏菌细菌至少有4.6的对数减少，将鸡蛋从加热的液体浴中移出并进入气态气氛（26），并使蛋与抗菌液接触（28 ）含有抗菌剂。优选地，蛋之后与诸如蜡的密封剂接触。在气态气氛中，蛋通过鸡蛋中的残余热量进一步巴氏杀菌至少5天的细菌减少。在气体气氛冷却期间，鸡蛋将抗菌流体吸收到壳内部和蛋壳之间的蛋中，并在鸡蛋中提供抗菌屏障。

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