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11. 发明申请

WO1998003212A1 BIOMECHANICAL HEART FOR EXTRA-AORTIC DIASTOLIC BALLOON PUMPING 审中-公开
标题翻译：生物医学心脏用于超声乳化双歧杆体气泡泵
公开(公告)号：WO1998003212A1
公开(公告)日：1998-01-29
申请号：PCT/FR1997001385
申请日：1997-07-24
申请人： IST CARDIOLOGY S.A. , GULDNER, Norbert , THUAUDET, Sylvain , HUTZENLAUB, Jens
发明人： IST CARDIOLOGY S.A.
IPC分类号： A61M01/10
CPC分类号： A61M1/1003 , A61M1/106 , A61M1/1062 , A61M1/107 , A61M1/1072 , A61M1/12 , A61M1/125 , A61M1/127
摘要： A biomechanical heart comprising extra-aortic diastolic balloon pumping means consisting of a pump housing (7) arranged between two ducts (5, 9) of an aortic shunt (6) actuated by a muscle (8) energised by electric pulses. A balloon (15) with a substantially ring-shaped cross-section is inserted between the inner walls of the pump housing (7) to define an axial channel (17) communicating with said ducts (5, 9) of the aortic shunt (6). Said channel is connected via a flexible tube (19) to means (20) for injecting a gas flow into said balloon (15) to inflate same and thus reduce the cross-sectional area of flow of the axial channel (17), then deflating said balloon to increase said cross-sectional area of flow of the axial channel (17).
摘要翻译：一种生物力学心脏，包括主动脉内舒张球囊泵送装置，该装置由布置在由电脉冲激发的肌肉（8）致动的主动脉分流器（6）的两个管道（5,9）之间的泵壳体（7）组成。具有大致环形横截面的球囊（15）插入在泵壳体（7）的内壁之间，以限定与主动脉分流器（6）的所述管道（5,9）连通的轴向通道（17））。所述通道经由柔性管（19）连接到用于将气流注入所述气囊（15）中以使其膨胀的装置（20），从而使轴向通道（17）的流动横截面积减小，然后放气所述气囊增加所述轴向通道（17）的所述流动横截面积。

12. 发明申请

WO1997044071A1 APPARATUS AND METHODS FOR REVASCULARIZATION AND PERFUSION 审中-公开
标题翻译：装置和方法用于重新放大和灌注
公开(公告)号：WO1997044071A1
公开(公告)日：1997-11-27
申请号：PCT/IL1997000162
申请日：1997-05-20
申请人： SUDAI, Amnon
IPC分类号： A61M01/10
CPC分类号： A61M1/1074 , A61B2017/00247 , A61B2018/00392 , A61M1/1008 , A61M1/106 , A61M1/107 , A61M1/1072 , A61M1/1081 , A61M1/12 , A61M1/125 , Y10S623/904
摘要： The invention is practiced by introducing a catheter (10) into the left ventricle of the heart. Deployment of an intraventricular pump assembly (12) from the end of catheter (10) is carried out by pushing holding device (24) in direction of the arrow (26). The tubes (20) of the intraventricular pump assembly (16) swing outward to protrude from hub (18). The first intraventricular pump (16) has a resilient bulb (30) attached to the hub (18). The tubes (20) are then self-anchored the myocardium such that they can act to inject blood into the myocardial wall from the ventricle.
摘要翻译：通过将导管（10）引入心脏的左心室来实施本发明。通过沿着箭头（26）的方向推动保持装置（24），从导管（10）的端部部署心室内泵组件（12）。心室内泵组件（16）的管（20）向外摆动以从轮毂（18）突出。第一脑室内泵（16）具有附接到轮毂（18）的弹性灯泡（30）。管（20）然后自我锚定心肌，使得它们可以起作用以将血液从心室注入心肌壁。

13. 发明申请

WO1997022373A1 DRIVE UNIT FOR MEDICAL EQUIPMENT 审中-公开
标题翻译：医疗设备驱动单元
公开(公告)号：WO1997022373A1
公开(公告)日：1997-06-26
申请号：PCT/JP1996003605
申请日：1996-12-10
申请人： NIPPON ZEON CO., LTD. , MIYATA, Shinichi , ITO, Kiyotaka
发明人： NIPPON ZEON CO., LTD.
IPC分类号： A61M01/10
CPC分类号： A61M1/106 , A61M1/107 , A61M1/1072 , A61M1/1086 , A61M1/125
摘要： A drive unit for medical equipment in which, when a pressure detected by a conduit pressure sensor (15) becomes lower than a predetermined value, a first solenoid valve (63) is closed and a second solenoid valve (68) is opened, so that a conduit (18) is replenished with a gas from a secondary gas tank (64), and the amount of gas to be supplied is calculated based upon a change in the pressure detected by a tank pressure sensor (65). In using the equipment, the leakage of gas under normal condition can be easily distinguished from the leakage of gas under abnormal condition. Desirably, the drive unit has a gas supply device (60) which detects the pressure in the conduit (18) at a timing of changing a balloon (22) from the contracted state over to the inflated state and replenishes the conduit (18) with the gas so that the detected pressure will reach a predetermined value, and further has a control unit (10b) for changing the desired value. Preferably, when the interval between inflation and contraction of the balloon (22) is short, the inflation drive is stopped for one pulse, the pressure in the balloon is stabilized and is then detected, and the gas is replenished based upon this pressure. Preferably, the drive unit has a pressure transmission device having vent grooves (52, 54) to permit the residual fluid existing in the intimate contact between a diaphragm (46) and a first inner surface (49) or a second inner surface (51) to escape to an input port (48) or to an output port (50).
摘要翻译：一种用于医疗设备的驱动单元，其中当由管道压力传感器（15）检测到的压力变得低于预定值时，关闭第一电磁阀（63）并打开第二电磁阀（68），使得补充来自二次气体罐（64）的气体的管道（18），并且基于由罐式压力传感器（65）检测到的压力变化来计算要供给的气体量。在使用设备时，气体在正常状态下的泄漏可以很容易地与异常情况下的气体泄漏区分开来。理想地，驱动单元具有气体供给装置（60），其在将气囊（22）从收缩状态改变到膨胀状态的时刻检测导管（18）中的压力，并且用使得检测到的压力将达到预定值，并且还具有用于改变期望值的控制单元（10b）。优选地，当气球（22）的充气和收缩之间的间隔短时，一个脉冲的充气驱动停止，气囊中的压力被稳定并被检测，并且基于该压力补充气体。优选地，驱动单元具有压力传递装置，其具有排气槽（52,54），以允许存在于隔膜（46）和第一内表面（49）或第二内表面（51）之间紧密接触的残留流体，逃逸到输入端口（48）或输出端口（50）。

14. 发明申请

WO1995023000A2 RECIPROCATING PUMP ARRANGEMENT 审中-公开
标题翻译：再生泵装置
公开(公告)号：WO1995023000A2
公开(公告)日：1995-08-31
申请号：PCT/US1995002416
申请日：1995-02-24
申请人： GENERAL DYNAMICS CORPORATION , PASQUE, Michael, K.
发明人： GENERAL DYNAMICS CORPORATION , LARSON, Carl, O., Jr. , SMITH, James, S. , CHAPMAN, John, H. , SLIMON, Scot, A. , TRAHAN, John, D. , BROZEK, Robert, J. , FRANCO, Alberto , McGARVEY, John, J. , ROSEN, Marvin, E.
IPC分类号： A61M01/10
CPC分类号： A61M1/101 , A61M1/1005 , A61M1/1008 , A61M1/1055 , A61M1/1081 , A61M1/1086 , A61M1/1096 , A61M1/12 , A61M1/122 , A61M1/127 , A61M2205/8243 , H02K7/14 , H02K41/031
摘要： In one embodiment described in the specification, a surgically implantable reciprocating pump employs a check valve as the piston, which is driven by a permanent magnet linear electric motor to assist either side of the natural heart. The pump is implanted in the aorta or pulmonary artery using vascular attachment cuffs such as flexible cuffs for suturing at each end with the pump output directly in line with the artery. The pump is powered by surgically implanted rechargeable batteries. In another embodiment, pairs of pumps are provided to replace or assist the natural heart or to provide temporary blood flow throughout the body, for example, during operations to correct problems with the natural heart.
摘要翻译：在说明书中描述的一个实施例中，手术可植入的往复泵采用止回阀作为活塞，其由永磁线性电动机驱动以辅助自然心脏的任一侧。使用血管附着袖口（例如柔性袖口）将泵植入主动脉或肺动脉，用于在每端用于缝合直接与动脉一致的泵输出。该泵由手术植入的可充电电池供电。在另一个实施例中，提供成对的泵以替代或辅助天然心脏或者在整个身体中提供临时血液流动，例如在纠正自然心脏问题的操作期间。

15. 发明申请

WO1995004558A1 BUBBLE REMOVING METHOD FOR CENTRIFUGAL PUMPS 审中-公开
标题翻译：用于离心泵的泡沫去除方法
公开(公告)号：WO1995004558A1
公开(公告)日：1995-02-16
申请号：PCT/JP1994001298
申请日：1994-08-05
申请人： SENKO MEDICAL INSTRUMENT MFG. CO., LTD. , NIKKISO CO., LTD. , KUWANA, Katsuyuki , ISHII, Shuichi , AIZAWA, Takeshi , ITO, Kazuyuki , MATSUURA, Motonori
发明人： SENKO MEDICAL INSTRUMENT MFG. CO., LTD. , NIKKISO CO., LTD.
IPC分类号： A61M01/10
CPC分类号： A61M1/3629 , A61M1/1006 , A61M1/101 , A61M1/1036
摘要： A blood delivery port (18) is inclined upward so that a perpendicular line (X) passing the center (O &cir& _) of a centrifugal pump body (12) is positioned between two straight lines ( alpha , beta ) which connect together two circumferential joint points (A, B) in a joint portion between the blood delivery port (18) and a centrifugal chamber (15) and the centre (O &cir& _), and the centrifugal pump body (12) is supported on a driving unit (13) with a blood take-in port (17) inclined upward at an angle larger than that between an inner circumferential surface of the centrifugal chamber (15) and the axis thereof. After the centrifugal chamber has been filled with a liquid, the driving of a rotary body is done in a low-speed mode, a stopping mode and a high-speed mode in the mentioned order. According to the present invention, the stagnation of bubbles in the centrifugal chamber (15) in the centrifugal pump body (12) at the time of starting the circulation of blood to a circuit such as a pump-oxygenator can be prevented reliably.
摘要翻译：血液输送口（18）向上倾斜，使得通过离心泵体（12）的中心（O＆Cir）的垂直线（X）位于两条直线（α，β）之间，两条直线（α，β）在血液输送口（18）和离心室（15）与中心（O＆Cir）之间的接合部分和离心泵体（12）中的接合点（A，B）被支撑在驱动单元 13），其具有以比离心室（15）的内周表面和其轴线之间大的角度向上倾斜的血液入口（17）。在离心室已经充满液体之后，旋转体的驱动以上述顺序的低速模式，停止模式和高速模式进行。根据本发明，可以可靠地防止在开始血液循环到诸如泵 - 氧合器之类的电路时离心泵体（12）中的离心室（15）中的气泡停滞。

16. 发明申请

WO1995000186A1 BLOOD PUMP 审中-公开
标题翻译：血液泵
公开(公告)号：WO1995000186A1
公开(公告)日：1995-01-05
申请号：PCT/US1994007305
申请日：1994-06-28
申请人： BAXTER INTERNATIONAL INC.
发明人： BAXTER INTERNATIONAL INC. , RAIBLE, Donald, A.
IPC分类号： A61M01/10
CPC分类号： F04D29/2277 , A61M1/10 , A61M1/101 , A61M1/1012 , A61M1/1013 , A61M1/1029 , A61M1/1034 , A61M1/1036 , F05B2260/604 , Y10S415/90
摘要： A dynamic blood pump (10) includes a rotating core member (70) and rotating ring portion (76) effective to pre-spin blood before the blood enters helical pumping channels (96) of the pump. The blood is pumped and further rotated as it moves axially along the helical channels (96) toward a centrifugal section of the pump (40). At the centrifugal pumping section circumferential velocity differentials are also controlled to diminish damage to the blood. Outwardly of the centrifugal pumping section, a forced-vortex pumping section communicates the pumped blood to an exit port.
摘要翻译：动态血液泵（10）包括旋转的芯构件（70）和旋转环部分（76），其有效地在血液进入泵的螺旋泵送通道（96）之前预先旋转血液。当血液被泵送并进一步沿着螺旋通道（96）朝向泵（40）的离心部分轴向移动时旋转。在离心泵送部分，圆周速度差也被控制以减少对血液的损伤。在离心泵送部分的外部，强迫涡流泵送部分将泵送的血液连通到出口。

17. 发明申请

WO1994026326A1 METHOD OF TRAINING A SKELETAL MUSCLE FOR A BIOMECHANICAL HEART AND BIOMECHANICAL HEART USING SAID MUSCLE 审中-公开
标题翻译：使用合理肌肉训练生物医学心脏和生物医学心脏的骨骼肌肉的方法
公开(公告)号：WO1994026326A1
公开(公告)日：1994-11-24
申请号：PCT/FR1994000571
申请日：1994-05-13
申请人： GULDNER, Norbert , THUAUDET, Sylvain
IPC分类号： A61M01/10
CPC分类号： A61M1/1053 , A61M1/1003 , A61M1/106 , A61M1/107 , A61M1/12 , A61M1/127
摘要： A method for dynamically training a skeletal muscle (1) to be used for a biomechanical heart involves wrapping the skeletal muscle around a deformable training device (2) which can contract, resistance to contraction being provided, and recover its initial form. The skeletal muscle is stimulated by periodic electrical impulses. In a first stage, the skeletal muscle (1) is stimulated by electrical impulses at a frequency increasing with time, and in a second stage the contraction resistance of the deformable training device (2) is increased progressively, the first and second stages possibly overlapping slightly. A biomechanical heart operated by a skeletal muscle having undergone said dynamic training is also disclosed.
摘要翻译：用于动态训练用于生物力学心脏的骨骼肌（1）的方法包括将骨骼肌包围在可收缩的抗变性训练装置（2）周围，并且恢复其初始形式。骨骼肌被周期性电脉冲刺激。在第一阶段，骨骼肌（1）以随时间增加的频率被电脉冲刺激，并且在第二阶段中，可变形训练装置（2）的收缩阻力逐渐增加，第一和第二阶段可能重叠略。还公开了经过所述动态训练的由骨骼肌操作的生物力学心脏。

18. 发明申请

WO1991008003A1 ELECTROHYDRAULIC DRIVE FOR PUMPS E.G. ARTIFICIAL HEARTS 审中-公开
标题翻译：用于泵浦的电动驱动器人为听力
公开(公告)号：WO1991008003A1
公开(公告)日：1991-06-13
申请号：PCT/CA1990000417
申请日：1990-11-26
申请人： TANNEY, Dorothy, A. +lf , NATIONAL RESEARCH COUNCIL OF CANADA , TANNEY, Dorothy, A. , HAYES, William, F.
发明人： TANNEY, Dorothy, A. +lf , NATIONAL RESEARCH COUNCIL OF CANADA , TANNEY, Dorothy, A. , TANNEY, John, W. +di
IPC分类号： A61M01/10
CPC分类号： A61M1/1065 , A61M1/1037 , A61M1/106 , A61M1/1062 , A61M1/1096 , A61M1/12 , A61M1/122
摘要： A primary fluid actuated, secondary fluid propelling system, suitable for use, for example, as an implantable, artificial heart device, comprises a unidirectional pump for pumping electrorheological fluid, two return loops connected to the pump, and for each return loop, two electrorheological valves therein in series flow, and a primary fluid actuated, secondary fluid propelling device connected to that loop at a position between the two electrorheological valves therein. The primary fluid actuated, secondary fluid propelling devices may comprise a casing having the interior thereof divided by a pressure transmitting flexible diaphragm into a first cavity for receiving electrorheological fluid from that return loop, and a second cavity for propelling the secondary fluid. The electrorheological valves are actuated to pressurize one first cavity while emptying the other and vice versa. In heart assist pump embodiments of the present invention, the primary fluid actuated, secondary fluid propelling device is replaced by, for example, a flexible container for placement in the body cavity for in operation, transmitting fluid pressure within the cavity.

19. 发明申请

WO1990001347A1 CHRONIC VENTRICULAR ASSIST SYSTEM 审中-公开
标题翻译： CHRONIC VENTRICULAR ASSIST系统
公开(公告)号：WO1990001347A1
公开(公告)日：1990-02-22
申请号：PCT/US1989003385
申请日：1989-08-07
申请人： NIMBUS MEDICAL, INC.
发明人： NIMBUS MEDICAL, INC. , MOISE, John, C. , WAMPLER, Richard, C. , BUTLER, Kenneth, C.
IPC分类号： A61M01/10
CPC分类号： A61M1/1031 , A61M1/101 , A61M1/1017 , A61M1/102 , A61M1/12 , A61M1/122 , A61M1/127 , Y10S415/90
摘要： An implantable ventricular assist system uses a small high-speed axial flow blood pump (16) which may be grafted into the patient's circulatory system. The pump includes a blood tube (12) in which the pump rotor (18) and stator (20) are coaxially contained, and a motor stator (14) surrounding the blood duct. A permanent magnet motor rotor (19) is integral with the pump rotor (18). Purge fluid for the hydrodynamic bearings (28, 30) of the device and power for the motor are preferably percutaneously introduced from extracorporeal sources worn by the patient. The purge fluid is introduced into the pump stator blades (22). This construction avoids the creation of discontinuities in the blood path wall due to the routing of drive power and/or fluid supply elements through the blood path wall. The described construction greatly reduces the size of the implant needed for a given blood flow rate and enhances its physiological compatibility with the body.

20. 发明申请

WO1999002204A1 TRANSPORT PUMP AND ORGAN STABILIZATION APPARATUS INCLUDING RELATED METHODS 审中-公开
标题翻译：运输泵和有机体稳定装置，包括相关方法
公开(公告)号：WO1999002204A1
公开(公告)日：1999-01-21
申请号：PCT/US1997018674
申请日：1997-10-14
申请人： A-MED SYSTEMS, INC. , ABOUL-HOSN, Walid
发明人： A-MED SYSTEMS, INC.
IPC分类号： A61M01/10
CPC分类号： A61M1/3653 , A61M1/1008 , A61M1/101 , A61M1/1012 , A61M1/1029 , A61M1/1086 , A61M1/122 , A61M1/125 , A61M1/3659 , A61M2205/32 , A61M2205/3334 , Y10S415/90
摘要： A surgical pump suitable for bodily fluids, normally blood, usable in the course of surgical interventions as an alternative to the traditional CPB (cardio pulmonary bypass) making use of external blood pumps. It consists of an intake cannula (20) which is inserted with its first (distal) end in a first vessel, an outflow cannula (30) coaxial for some length with, and larger than the first cannula, which is inserted with its first (distal) end in a second vessel, both second ends of the coaxial cannulas being connected with a pump housing (52) having an inlet (62) for the inner cannula and outflow windows (64) for the outer cannula, a rotor impeller (70) housed in the housing and connected with an electric motor (80) rotating coaxially below the pump housing, the housing having inner (56) and outer (59) passageways which allow inflow, change of flow direction (reversal) and outflow of the fluid, thus producing two coaxial counter flowing flows in the coaxial cannulas. The pump can be used making use of a single portal. Inflatable balloons can be used to stabilize the cannulas in situ and to stabilize the walls of the organs or vessels where the cannulas are inserted.
摘要翻译：一种适用于体液（通常为血液）的外科手术泵，可在外科手术过程中使用，作为使用外部血液泵的传统CPB（心脏肺动脉旁路）的替代方法。它包括入口插管（20），其插入其第一（远端）的第一容器中，与第一插管一同长度并与其大于第一插管同轴的流出插管（30）远端）端部在第二容器中，同轴插管的两个第二端与泵壳体（52）连接，泵壳体具有用于内套管的入口（62）和用于外套管的流出窗口（64），转子叶轮（70 ）容纳在壳体中并且与同轴地在泵壳体下方旋转的电动机（80）连接，壳体具有内部（56）和外部（59）通道，其允许流体流动方向（反转）和流出的改变，从而在同轴插管中产生两个同轴对流流动。该泵可以使用单个门户使用。可以使用充气气球来原位稳定插管，并稳定插入插管的器官或血管的壁。

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