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    • 13. 发明申请
    • BODY ASSOCIATED DEVICE AND METHOD OF MAKING SAME
    • 身体相关装置及其制造方法
    • WO2012149466A2
    • 2012-11-01
    • PCT/US2012035650
    • 2012-04-27
    • PROTEUS BIOMEDICAL INCARNE LAWRENCEHUTCHISON JAMES
    • ARNE LAWRENCEHUTCHISON JAMES
    • A61B5/0402A61B5/0408A61B5/0424
    • A61B5/6833A61B5/04087A61B5/04284A61B5/681A61B5/6831A61B2560/0443A61B2562/0214A61B2562/125A61B2562/164
    • Methods of manufacturing a body associated device are disclosed. The methods include providing an inlay substrate comprising a first side, a second side, and at least one conductive trace and providing an interposer substrate comprising a first side, a second side, and at least one conductive trace. An electrically conductive layer is applied to the first side of the inlay substrate. The at least one conductive trace is electrically coupled to the conductive layer. The first side of the interposer substrate is coupled to the first side of the inlay substrate to form a subassembly. The at least one conductive trace on the interposer substrate is electrically coupled to the at least one conductive trace on the inlay substrate through the electrically conductive layer. A body associated device with a wet electrode manufactured in accordance with a first process is disclosed. A body associated device with a dry electrode manufactured in accordance with a second process is disclosed.
    • 公开了制造身体相关装置的方法。 所述方法包括提供包含第一侧,第二侧和至少一个导电迹线的镶嵌衬底,并提供包括第一侧,第二侧和至少一个导电迹线的插入物衬底。 将导电层施加到嵌体衬底的第一侧。 所述至少一个导电迹线电耦合到所述导电层。 插入器衬底的第一侧耦合到嵌入衬底的第一侧以形成子组件。 插入器衬底上的至少一个导电迹线通过导电层电耦合到嵌入衬底上的至少一个导电迹线。 公开了一种根据第一种方法制造的具有湿电极的本体关联装置。 公开了一种具有根据第二工艺制造的干电极的本体关联装置。
    • 18. 发明申请
    • MULTIPLE ELECTRODE VECTORS FOR IMPLANTABLE CARDIAC TREATMENT DEVICES
    • 用于植入式心脏治疗设备的多电极向量
    • WO2005011809A3
    • 2005-05-06
    • PCT/US2004024426
    • 2004-07-28
    • CAMERON HEALTH INCWARREN JAY ABARDY GUST H
    • WARREN JAY ABARDY GUST H
    • A61B5/024A61B5/0402A61B5/042A61B5/0424A61B5/0428A61B5/07A61N1/362A61N1/368A61N1/39
    • A61B5/0424A61B5/0402A61B5/042A61B5/04288A61B5/076A61B5/7207A61N1/3622A61N1/3925
    • The implantable cardiac treatment system of the present invention is capable of choosing the most appropriate electrode vector to sense within a particular patient. In certain embodiments, the implantable cardiac treatment system determines the most appropriate electrode vector for continuous sensing based on which electrode vector results in the greatest signal amplitude, or some other useful metric such as signal-to-noise ratio (SNR). The electrode vector possessing the highest quality as measured using the metric is then set as the default electrode vector for sensing. Additionally, in certain embodiments of the present invention, a next alternative electrode vector is selected based on being generally orthogonal to the default electrode vector. In yet other embodiments of the present invention, the next alternative electrode vector is selected based on possessing the next highest quality metric after the default electrode vector. In some embodiments, if analysis of the default vector is ambiguous, the next alternative electrode vector is analyzed to reduce ambiguity.
    • 本发明的可植入心脏处置系统能够选择最合适的电极矢量以在特定患者内感测。 在某些实施例中,植入式心脏处理系统基于哪个电极矢量导致最大的信号幅度或某个其他有用的度量(例如信噪比(SNR))来确定用于连续感测的最合适的电极矢量。 然后将使用度量测量的具有最高质量的电极矢量设置为用于感测的默认电极矢量。 另外,在本发明的某些实施例中,基于通常与默认电极矢量正交来选择下一替代电极矢量。 在本发明的其他实施例中,基于拥有在默认电极矢量之后的下一个最高质量度量来选择下一个替代电极矢量。 在一些实施例中,如果默认向量的分析不明确,则分析下一替代电极向量以减少模糊性。
    • 19. 发明申请
    • METHOD AND APPARATUS FOR IDENTIFYING LEAD-RELATED CONDITIONS USING LEAD IMPEDANCE MEASUREMENTS
    • 使用铅阻抗测量来识别铅相关条件的方法和设备
    • WO2004028617A3
    • 2004-05-21
    • PCT/US0331043
    • 2003-09-30
    • MEDTRONIC INC
    • GUNDERSON BRUCE DBONDS CHAD APATEL AMISHA SDUFFIN EDWIN G
    • A61B5/0424A61N1/08A61N1/39A61N1/37
    • A61N1/3925A61B5/0424A61N2001/083
    • A method and apparatus for automatically detecting and diagnosing lead-related conditions is provided. Specifically, relatively short-term and relatively long-term impedance parameters are determined for detecting an impedance trend indicative of a lead-related condition such as an open circuit, which may be due to a conductor fracture or poor connection to an associated implantable medical device, or a short circuit due to an insulation breach. Monitoring of multiple lead impedance parameters is performed to diagnose a lead-related condition based on a number of diagnostic criteria. Supplementary analysis of multiple lead impedance parameter trends may be performed to identify lead-specific conditions, such as metal ion oxidation induced insulation degradation. A lead-related condition diagnosis and supporting data are stored in memory for uplinking to an external device for review by a clinician. A recommended corrective action and/or a patient notification signal for a lead-related condition may optionally be provided.
    • 提供了用于自动检测和诊断引线相关状况的方法和设备。 具体而言,确定相对短期和相对长期的阻抗参数,以用于检测指示与引线相关的状况(例如开路)的阻抗趋势,这可能是由于导体断裂或与相关联的可植入医疗设备 ,或由于绝缘破坏而导致的短路。 执行多个导联阻抗参数的监测以基于多个诊断标准诊断导联相关状况。 可以执行对多个铅阻抗参数趋势的补充分析以识别铅特定条件,例如金属离子氧化引起的绝缘劣化。 引导相关的状况诊断和支持数据被存储在存储器中用于上传到外部设备以供临床医生审查。 可以可选地提供用于铅相关病症的推荐校正动作和/或患者通知信号。