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11. 发明申请

WO2013027138A1 FREQUENCY DEPENDENT COMBINATION OF X-RAY IMAGES OF DIFFERENT MODALITIES 审中-公开
标题翻译：不同模式的X射线图像的频率相关组合
公开(公告)号：WO2013027138A1
公开(公告)日：2013-02-28
申请号：PCT/IB2012/053854
申请日：2012-07-27
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , MAACK, Hanns-Ingo , RÖSSL, Ewald , KOEHLER, Thomas , PROKSA, Roland
发明人： MAACK, Hanns-Ingo , RÖSSL, Ewald , KOEHLER, Thomas , PROKSA, Roland
IPC分类号： G06T5/50
CPC分类号： G06T11/60 , A61B6/484 , G06T5/50 , G06T2207/10116 , G06T2207/20056 , G06T2207/20221 , G06T2207/30004
摘要： The present invention relates to X-ray imaging technology. In phase-contrast imaging, different types of image information, e.g. absorption image information and differential phase-contrast image information, may be obtained by a single image acquisition process. Individual types of image information comprise different image properties. The present invention relates to a frequency dependent combination of different types of image information to obtain a combined image having improved properties over the individual image information and their respective image information type. Accordingly, an apparatus (56) as well as a method (100) for image processing in X-ray imaging of an object is provided comprising receiving (102) first image information of the object of a first image information type, receiving (104) second image information of the object of a second image information type,wherein the second image information type is different from the first image information type. Subsequently the first image information and the second image information is combined(106)to obtain combined image information of the object, wherein the combination of the first image information and the second image information is a frequency-dependent combination, depending on the spatial frequency of the first image information and the second image information.
摘要翻译：本发明涉及X射线成像技术。在相位对比成像中，不同类型的图像信息，例如，吸收图像信息和差分相位差图像信息可以通过单个图像获取处理获得。各种类型的图像信息包括不同的图像属性。本发明涉及不同类型的图像信息的频率相关组合，以获得具有相对于各个图像信息及其各自的图像信息类型具有改进的特性的组合图像。因此，提供了一种装置（56）以及用于对象的X射线成像中的图像处理的方法（100），包括接收（102）第一图像信息类型的对象的第一图像信息，接收（104）第二图像信息类型的对象的第二图像信息，其中第二图像信息类型与第一图像信息类型不同。随后，将第一图像信息和第二图像信息组合（106）以获得对象的组合图像信息，其中第一图像信息和第二图像信息的组合是频率相关组合，其取决于第一图像信息和第二图像信息。

12. 发明申请

WO2013014554A1 IMAGE GENERATION APPARATUS 审中-公开
标题翻译：图像生成装置
公开(公告)号：WO2013014554A1
公开(公告)日：2013-01-31
申请号：PCT/IB2012/053346
申请日：2012-07-02
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GmbH , KOEHLER, Thomas
发明人： KOEHLER, Thomas
IPC分类号： A61B6/03 , G06T5/50 , G06T11/00
CPC分类号： G06T11/008 , A61B6/032 , A61B6/037 , A61B6/463 , A61B6/465 , A61B6/5205 , A61B6/5235 , A61B6/5258 , G06T5/002 , G06T5/50 , G06T2207/10081 , G06T2207/30004
摘要： The invention relates to an image generation apparatus for generating an image of an object. An image providing unit (11, 16) provides a first image of the object and a second image of the object, wherein the first image has a smaller noise level than the second image. A display window providing unit (12) provides a display window being indicative of the range of image values shown on a display (14), and a combining unit (13) generates a combination image by combining the first image and the second image depending on the window width of the provided display window. This allows considering the influence of the display window on the noise appearance. Thus, by taking into account the first image and the second image having different noise levels and the provided display window, a combined image can be generated, which has an improved noise appearance.
摘要翻译：本发明涉及一种用于生成对象的图像的图像生成装置。图像提供单元（11,16）提供对象的第一图像和对象的第二图像，其中第一图像具有比第二图像更小的噪声水平。显示窗口提供单元（12）提供指示显示器（14）上显示的图像值的范围的显示窗口，并且组合单元（13）通过组合第一图像和第二图像来生成组合图像，这取决于提供的显示窗口的窗口宽度。这允许考虑显示窗对噪声外观的影响。因此，通过考虑具有不同噪声水平的第一图像和第二图像以及所提供的显示窗口，可以生成具有改善的噪声外观的组合图像。

13. 发明申请

WO2012080900A1 METHOD AND DEVICE FOR ANALYSING A REGION OF INTEREST IN AN OBJECT USING X-RAYS 审中-公开
标题翻译：用于分析使用X-RAYS的对象中的兴趣区域的方法和装置
公开(公告)号：WO2012080900A1
公开(公告)日：2012-06-21
申请号：PCT/IB2011/055463
申请日：2011-12-05
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , CARLSEN, Ingwer-Curt , KOEHLER, Thomas , MARTENS, Gerhard , RÖSSL, Ewald , WIEMKER, Rafael
发明人： CARLSEN, Ingwer-Curt , KOEHLER, Thomas , MARTENS, Gerhard , RÖSSL, Ewald , WIEMKER, Rafael
IPC分类号： G01N23/04 , G01N23/20
CPC分类号： G06T7/0012 , G01N23/046 , G01N2223/419
摘要： A method and a device for analyzing a region of interest in an object is proposed. The method comprises: (a) providing measurement data by a differential phase contrast X-ray imaging system, and (b) analyzing characteristics of the object in the region of interest. Therein, the measurement data comprise a 2-dimensional or 3 -dimensional set of pixels wherein for each pixel the measurement data comprises three types of image data spatially aligned with each other, including (i) absorption representing image data A, (ii) differential phase contrast representing image data D, and (iii) coherence representing image data C. The analyzing step is based, for each pixel, on a combination of at least two of information comprised in the absorption representing image data A and information comprised in the differential phase contrast representing image data D and information comprised in the coherence representing image data C.
摘要翻译：提出了一种用于分析对象中的感兴趣区域的方法和装置。该方法包括：（a）通过差分相位X射线成像系统提供测量数据，以及（b）分析感兴趣区域中物体的特征。其中，测量数据包括2维或3维像素集合，其中对于每个像素，测量数据包括彼此空间对准的三种类型的图像数据，包括（i）表示图像数据A的吸收，（ii）差分表示图像数据D的相位对比度和（iii）表示图像数据C的相干性。分析步骤基于每个像素，包括在表示图像数据A的吸收中包括的信息中的至少两个信息和差分中包含的信息表示图像数据D的相位对比度和表示图像数据C的相干性中包含的信息。

14. 发明申请

WO2011070521A1 CALIBRATION OF DIFFERENTIAL PHASE-CONTRAST IMAGING SYSTEMS 审中-公开
标题翻译：差分相位成像系统的校准
公开(公告)号：WO2011070521A1
公开(公告)日：2011-06-16
申请号：PCT/IB2010/055664
申请日：2010-12-08
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , VOGTMEIER, Gereon , ENGEL, Klaus Jürgen , GELLER, Dieter , KOEHLER, Thomas , ROESSL, Ewald
发明人： VOGTMEIER, Gereon , ENGEL, Klaus Jürgen , GELLER, Dieter , KOEHLER, Thomas , ROESSL, Ewald
IPC分类号： A61B1/00
CPC分类号： A61B6/4291 , A61B6/4092 , A61B6/484 , A61B6/583 , G21K2207/005
摘要： The present invention relates to an X-ray imaging system and a method for differential phase - contrast imaging of an object. To improve calibration of differential phase - contrast imaging systems and the alignment of the gratings an X-ray imaging system is provided that comprises an X-ray emitting arrangement providing at least partially coherent X-ray radiation and an X-ray detection arrangement comprising a phase- shift diffraction grating, a phase analyzer grating, and an X-ray image detector, all arranged along an optical axis. For stepping, the gratings and/or the X-ray emitting arrangement are provided with at least two actuators arranged opposite to each other with reference to the optical axis. For calibration, calibration projections are acquired without an object, wherein, the emitted X-ray radiation or one of the gratings is stepwise displaced with a calibration displacement value. For examination, measurement projections are acquired with an object, wherein the emitted X-ray radiation or one of the gratings is stepwise displaced with a measurement, a calibration projection is associated to each of the measurement projections by registering the latter with the calibration projections.
摘要翻译：本发明涉及一种用于对象的差分相位对比成像的X射线成像系统和方法。为了改进差分相位对比成像系统的校准和光栅的对准，提供了一种X射线成像系统，其包括提供至少部分相干X射线辐射的X射线发射装置和包括相移衍射光栅，相位分析仪光栅和X射线图像检测器，均沿光轴排列。对于步进，光栅和/或X射线发射装置设置有相对于光轴彼此相对布置的至少两个致动器。对于校准，在没有物体的情况下获取校准投影，其中，所发射的X射线辐射或其中一个光栅以校准位移值逐步位移。为了进行检查，用物体获取测量投影，其中所发射的X射线辐射或其中一个光栅通过测量而逐步移位，通过将校准投影与校准投影相对应地将校准投影与每个测量投影相关联。

15. 发明申请

WO2010134012A1 GRATING FOR PHASE-CONTRAST IMAGING 审中-公开
标题翻译：用于相位对比成像的图像
公开(公告)号：WO2010134012A1
公开(公告)日：2010-11-25
申请号：PCT/IB2010/052168
申请日：2010-05-17
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , KOEHLER, Thomas , ROESSL, Ewald
发明人： KOEHLER, Thomas , ROESSL, Ewald
IPC分类号： G21K1/06
CPC分类号： G21K1/06 , G21K2207/005
摘要： The invention relates to gratings for X-ray differential phase-contrast imaging, a focus detector arrangement and X-ray system for generating phase-contrast images of an object and a method of phase-contrast imaging for examining an object of interest. In order to provide gratings with a high aspect ratio but low costs, a grating for X-ray differential phase- contrast imaging is proposed, comprising a first sub-grating (112), and at least a second sub- grating (114; 116; 118), wherein the sub-gratings each comprise a body structure (120) with bars (122) and gaps (124) being arranged periodically with a pitch (a), wherein the sub- gratings (112; 114; 116; 118) are arranged consecutively in the direction of the X-ray beam, and wherein the sub-gratings (112; 114; 116; 118) are positioned displaced to each other perpendicularly to the X-ray beam.
摘要翻译：本发明涉及用于X射线差分相位对比成像的光栅，用于产生对象的相位对比图像的焦点检测器布置和X射线系统以及用于检查感兴趣对象的相位对比成像方法。为了提供具有高纵横比但成本较低的光栅，提出了一种用于X射线差分相位对比成像的光栅，包括第一子光栅（112）和至少第二子光栅（114; 116 ; 118），其中所述子光栅各自包括具有杆（122）和间隙（124）的主体结构（120），所述杆具有间距（a）周期性地布置，其中所述子光栅（112; 114; 116; 118 ）沿X射线束的方向连续布置，并且其中子光栅（112; 114; 116; 118）被定位成垂直于X射线束彼此位移。

16. 发明申请

WO2009138933A1 METHOD AND SYSTEM FOR GENERATING AN X-RAY BEAN 审中-公开
标题翻译：用于生成X射线光束的方法和系统
公开(公告)号：WO2009138933A1
公开(公告)日：2009-11-19
申请号：PCT/IB2009/051906
申请日：2009-05-08
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , THRAN, Axel , FORTHMANN, Peter , PROKSA, Roland , KOEHLER, Thomas
发明人： THRAN, Axel , FORTHMANN, Peter , PROKSA, Roland , KOEHLER, Thomas
IPC分类号： H01J35/10 , H01J35/30 , H05G1/52 , H05G1/58 , A61B6/00
CPC分类号： H01J35/10 , H01J35/30 , H01J2235/086 , H05G1/52 , H05G1/58
摘要： To scan an object with differently shaped cone beams (112, 122), the present invention provides a CT scanner with a moveable X-ray tube (the meaning of "move the x-ray tube among a plurality of predefined positions" also covers the situation that the anode disk is moved among a plurality of corresponding positions, while the shell of the x-ray tube does not move). The X-ray tube is not only moveable along the axial direction, but also along the radial direction of the CT scanner gantry. The scanner comprises an X-ray tube, which X-ray tube further comprises: an anode disk (100), comprising a plurality of focal tracks (110, 120) each focal track being cone-shaped with an anode angle (114, 124) different from the anode angle(s) of the other focal track(s); and a first cathode (210), configured to emanate an electron beam targeting at least one of the plurality of focal tracks. When different focal tracks are bombarded by electron beams, different X-ray beams (112, 122) with differently shaped cone beams are generated.
摘要翻译：为了扫描具有不同形状的锥形束（112,122）的物体，本发明提供具有可移动X射线管的CT扫描器（“在多个预定位置中移动x射线管”的含义也覆盖使得阳极盘在多个对应位置之间移动，而X射线管的外壳不移动的情况）。 X射线管不仅可以沿轴向移动，而且可沿CT扫描仪台架的径向方向移动。所述扫描器包括X射线管，所述X射线管还包括：阳极盘（100），包括多个焦点轨道（110,120），每个焦点轨道呈圆锥形，具有阳极角（114,124 ）不同于另一个焦点轨道的阳极角度; 以及第一阴极（210），被配置为发射靶向所述多个焦点轨道中的至少一个的电子束。当不同的焦点轨道被电子束轰击时，产生具有不同形状的锥形束的不同的X射线束（112,122）。

17. 发明申请

WO2013030698A1 DIFFERENTIAL PHASE CONTRAST IMAGING WITH ENERGY SENSITIVE DETECTION 审中-公开
标题翻译：具有能量敏感检测的差分相位对比成像
公开(公告)号：WO2013030698A1
公开(公告)日：2013-03-07
申请号：PCT/IB2012/054032
申请日：2012-08-08
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GmbH , KOEHLER, Thomas , SCHLOMKA, Jens-Peter
发明人： KOEHLER, Thomas , SCHLOMKA, Jens-Peter
IPC分类号： G06T5/50 , G06T11/00
CPC分类号： G06T7/0014 , G01N23/046 , G06T5/50 , G06T11/005 , G06T2211/408
摘要： For correcting differential phase image data 52, differential phase image data 52 acquired with radiation at different energy levels is received, wherein the differential phase image data 52 comprises pixels 60, each pixel 60 having a phase gradient value 62a, 62b, 62c for each energy level. After that an energy dependent behavior of phase gradient values 62a, 62b, 62c of a pixel 60 is determined and a corrected phase gradient value 68 for the pixel 60 is determined from the phase gradient values 62a, 62b, 62c of the pixel 60 and a model for the energy dependence of the phase gradient values 62a, 62b, 62c.
摘要翻译：为了校正微分相位图像数据52，接收以不同能量级别的辐射获取的差分相位图像数据52，其中差分相位图像数据52包括像素60，每个像素60具有每个能量的相位梯度值62a，62b，62c 水平。之后，确定像素60的相位梯度值62a，62b，62c的与能量相关的行为，并且根据像素60的相位梯度值62a，62b，62c确定像素60的校正相位梯度值68和模型，用于相位梯度值62a，62b，62c的能量依赖性。

18. 发明申请

WO2012093361A2 IMAGING SYSTEM FOR IMAGING AN OBJECT 审中-公开
标题翻译：成像对象成像系统
公开(公告)号：WO2012093361A2
公开(公告)日：2012-07-12
申请号：PCT/IB2012/050037
申请日：2012-01-04
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , FORTHMANN, Peter , KOEHLER, Thomas
发明人： FORTHMANN, Peter , KOEHLER, Thomas
CPC分类号： G06T11/006 , G06T2211/416 , G06T2211/424
摘要： The invention relates to an imaging system for imaging an object. Projection data of the object are acquired by using a radiation source emitting primary radiation (14) from a primary focal spot (15) and unwanted secondary radiation (16) from secondary focal spots (17). A first image of the object is reconstructed from the acquired projection data, a forward projection of the secondary radiation through the first image is simulated for generating secondary projection data, and a second image is generated based on the acquired projection data and the secondary projection data. Since the secondary projection data, which can generally cause image artifacts, are determined, the reconstruction unit can consider these unwanted secondary projection data while reconstructing the second image, in order to reduce the influence of the secondary projection data on the reconstructed second image, thereby improving the image quality.
摘要翻译：本发明涉及一种用于对物体成像的成像系统。通过使用发射来自主焦点（15）的初级辐射（14）和来自次级焦点（17）的不想要的次级辐射（16）的辐射源获取物体的投影数据。根据所采集的投影数据重建物体的第一图像，模拟通过第一图像的二次辐射的正向投影以生成二次投影数据，并且基于所采集的投影数据和二次投影数据生成第二图像。由于确定了通常会导致图像伪影的次级投影数据，所以重建单元可以在重建第二图像时考虑这些不想要的次级投影数据，以便减少次级投影数据对重建的第二图像的影响，由此改善图像质量。

19. 发明申请

WO2011073863A1 COMPUTED TOMOGRAPHY APPARATUS 审中-公开
标题翻译：计算机图像设备
公开(公告)号：WO2011073863A1
公开(公告)日：2011-06-23
申请号：PCT/IB2010/055712
申请日：2010-12-10
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , KOEHLER, Thomas , PROKSA, Roland , ROESSL, Ewald
发明人： KOEHLER, Thomas , PROKSA, Roland , ROESSL, Ewald
IPC分类号： A61B6/03 , G01N23/04 , G06T11/00
CPC分类号： A61B6/032 , A61B6/469 , A61B6/542 , G01N23/046 , G01N2223/419 , G06T11/005 , Y10S378/901
摘要： The invention relates to a computed tomography apparatus for imaging an object. The computed tomography apparatus comprises a radiation source (2) for generating modulated radiation (4) traversing the object and a detector (6) for generating detection values depending on the radiation (4) after having traversed the object, while the radiation source (2) and the object are moved relative to each other. A weight providing unit (14) provides modulation weights for weighting the detection values depending on the modulation of the radiation (4) and a reconstruction unit (15) reconstructs an image of the object, wherein the detection values are weighted based on the provided modulation weights and an image of the object is reconstructed from the weighted detection values. This can allow to optimize the dose application to the object by modulating the radiation accordingly, wherein the reconstructed images still have a high quality.
摘要翻译：本发明涉及一种用于对物体成像的计算机断层摄影装置。计算机断层摄影装置包括用于产生经过物体的调制辐射（4）的辐射源（2）和用于在穿过物体之后产生取决于辐射（4）的检测值的检测器（6），而辐射源）并且对象相对于彼此移动。权重提供单元（14）提供调制权重，用于根据辐射（4）的调制对检测值进行加权，重建单元（15）重建对象的图像，其中基于所提供的调制对检测值进行加权从加权检测值重建对象的权重和图像。这可以通过相应地调节辐射来优化对物体的剂量应用，其中重建的图像仍然具有高质量。

20. 发明申请

WO2011070488A1 PHASE CONTRAST IMAGING 审中-公开
标题翻译：相位对比成像
公开(公告)号：WO2011070488A1
公开(公告)日：2011-06-16
申请号：PCT/IB2010/055561
申请日：2010-12-03
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , GELLER, Diester , ENGEL, Klaus, J. , VOGTMEIER, Gereon , KOEHLER, Thomas , ROESSL, Ewald
发明人： GELLER, Diester , ENGEL, Klaus, J. , VOGTMEIER, Gereon , KOEHLER, Thomas , ROESSL, Ewald
IPC分类号： A61B6/00 , G01N23/04
CPC分类号： A61B6/00 , A61B6/4291 , A61B6/4441 , A61B6/484
摘要： X-raydevices for Phase Contrast Imaging (PCI) are often built up with the help ofgratings. For large field-of-views (FOV), production cost and complexity of these gratings could increase significantly as they need to have a focused geometry. Instead of a pure PCI with a large FOV, this invention suggests to combine a traditional absorption X-rayimaging system with large-FOV with an insertable low-cost PCI systemwith small-FOV, The invention supports the user to direct the PCI systemwith reduced FOV to a region that he regards as most interesting for performing a PCI scan thus eliminating X-raydose exposure for scanning regions not interesting fora radiologist. The PCI scan may be generated on the basis of local tomography.
摘要翻译：用于相位对比成像（PCI）的X射线装置通常在格栅的帮助下建立。对于大视野（FOV）来说，这些光栅的生产成本和复杂性可能会因为需要聚焦几何而显着增加。本发明不是采用具有大FOV的纯PCI，而是将传统的吸收式X射线成像系统与大型FOV结合，并具有小FOV的可插入式低成本PCI系统。本发明支持用户将具有降低的FOV的PCI系统他认为最有意思的是进行PCI扫描，从而消除了对放射科医生不感兴趣的扫描区域的X射线摄影。可以基于局部断层摄影产生PCI扫描。

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