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11. 发明申请

WO2009056998A2 PERSONAL CARE ARTICLE WITH SUBSTRATE SURFACE TOPOGRAPHY FOR EVOKING A NEUROSENSORY SKIN RESPONSE 审中-公开
标题翻译：具有基底表面形貌的个人护理用品，用于感知神经灵敏性皮肤应答
公开(公告)号：WO2009056998A2
公开(公告)日：2009-05-07
申请号：PCT/IB2008053939
申请日：2008-09-26
申请人： KIMBERLY CLARK CO , COHEN JASON C , KOENIG DAVID W
发明人： COHEN JASON C , KOENIG DAVID W
IPC分类号： A61F13/15
CPC分类号： A61F13/51104
摘要： In a personal care article for contact with human skin, a non-woven substrate of the article has a longitudinal direction, a transverse direction and at least one skin-contact surface. A plurality of surface features is disposed on the at least one skin-contact surface in a sinusoidal wave-form along at least one of the longitudinal direction and the transverse direction of the substrate. The surface features have a height that generally defines an amplitude of the sinusoidal wave- form, and are spaced from each other a spatial distance. This spatial distance is at least in part a function of a movement speed at which the article is to be moved relative to the skin while in contact therewith. In one method of making such a substrate, the movement speed and a temporal frequency are selected and used to determine the spacing between surface features on the skin-contact surface of the substrate.
摘要翻译：在与人体皮肤接触的个人护理用品中，制品的无纺基材具有纵向，横向和至少一个皮肤接触表面。多个表面特征沿着衬底的纵向方向和横向方向中的至少一个以正弦波形式布置在所述至少一个皮肤接触表面上。表面特征具有通常限定正弦波形的幅度的高度，并且彼此间隔开空间距离。该空间距离至少部分地是制品在与其接触时相对于皮肤移动的移动速度的函数。在制造这种衬底的一种方法中，移动速度和时间频率被选择并用于确定衬底的皮肤接触表面上的表面特征之间的间隔。

12. 发明申请

WO2007070184A3 ANTIMICROBIAL SUBSTRATES WITH PEROXIDE TREATMENT 审中-公开
标题翻译：具有过氧化物处理的抗微生物基质
公开(公告)号：WO2007070184A3
公开(公告)日：2008-07-31
申请号：PCT/US2006043031
申请日：2006-11-03
申请人： KIMBERLY CLARK CO , KOENIG DAVID W , YAHIAOUI ALI , BAGWELL ALISON S
发明人： KOENIG DAVID W , YAHIAOUI ALI , BAGWELL ALISON S
IPC分类号： A01N25/34 , A01N25/18 , A01N59/00 , A01P1/00
CPC分类号： A61K33/40 , A01N25/34 , A61L2/23 , A61L2/232 , A01N59/00 , A01N33/12 , A01N25/22 , A01N25/10
摘要： An oxidizing antimicrobial treatment and products containing such treatment are described. The treatment involve, in part, preparing a substrate to accept an attachment of charged moieties, and a number of stabilized peroxide compounds on at least part of a surface of said substrate. When microbes, such as bacteria, having a net charge opposite to that of the charged moieties come in close proximity to the treated substrate surface, peroxide molecules from the substrate are activated and released to kill the microbes.
摘要翻译：描述了氧化性抗微生物处理和含有这种处理的产品。该处理部分地涉及制备底物以接受带电部分的附着物，以及在所述基材的至少部分表面上的多种稳定的过氧化物化合物。当具有与带电部分的净电荷相反的净电荷的微生物与处理的底物表面紧密接近时，来自底物的过氧化物分子被活化并释放以杀死微生物。

13. 发明申请

WO0128512A9 SELECTIVE REMOVAL OF CONTAMINANTS FROM A SURFACE USING ARTICLES HAVING MAGNETS 审中-公开
标题翻译：使用具有磁铁的文章从表面选择性去除污染物
公开(公告)号：WO0128512A9
公开(公告)日：2002-08-08
申请号：PCT/US0041054
申请日：2000-10-03
申请人： KIMBERLY CLARK CO
发明人： KOENIG DAVID W , NELSON BRENDA M , LANGE BETH ANNE
IPC分类号： A61K8/19 , A61Q19/10 , G01N33/536 , G01N33/553 , A61K7/48 , A61K7/50
CPC分类号： A61Q19/10 , A61K8/19 , A61K2800/47 , Y10S436/806
摘要： A system and method for removing contaminants from a surface. The system is designed to use particles having means thereon which are capable of selectively binding to a contaminant or contaminants of interest. The particles are applied to the surface whereupon the contaminants bind to the particle. When the particle is removed, the desired contaminants are also removed. Preferably, the present invention utilizes magnetic particles having iron therein. The particles may then be readily removed using magnets. The means for binding the contaminant to the particle preferably comprise a ligand or a charge specifically designed to remove the contaminant of interest. The particles may be included in a carrier to facilitate their application to the surface. The invention is especially useful for the removal of contaminants from skin.
摘要翻译：用于从表面去除污染物的系统和方法。该系统设计为使用能够选择性地结合污染物或感兴趣的污染物的具有其上的装置的颗粒。颗粒被施加到表面，因此污染物与颗粒结合。当除去颗粒时，也去除所需的污染物。优选地，本发明使用其中具有铁的磁性颗粒。然后可以使用磁体容易地除去颗粒。用于将污染物与颗粒结合的方法优选包含特异性设计用于去除感兴趣污染物的配体或电荷。颗粒可以包含在载体中以便于它们施加到表面。本发明特别可用于从皮肤去除污染物。

14. 发明申请

WO0144500A8 METHOD AND DEVICE FOR FLUID QUALITY MEASUREMENT 审中-公开
标题翻译：用于流体质量测量的方法和装置
公开(公告)号：WO0144500A8
公开(公告)日：2001-10-25
申请号：PCT/US0042822
申请日：2000-12-13
申请人： KIMBERLY CLARK CO
发明人： BRUNNER MICHAEL S , WEI NING , KOENIG DAVID W
IPC分类号： B03C1/01 , G01N33/18 , C12Q1/00
CPC分类号： B03C1/01 , C12Q1/22
摘要： The present invention is directed to a method and device for measuring water quality. The present invention utilizes displaceable particles located upon a substrate for measuring the water quality. The device allows the particles to be displaced by attaching bacteria to the substrate. The presence or the amount of bacteria in water is detected over a relatively short time period so as to provide a device or method for near instantaneous indication or measurement of water quality.
摘要翻译：本发明涉及一种用于测量水质的方法和装置。本发明利用位于基底上的可移位颗粒来测量水质。该装置允许通过将细菌附着到基底来移位颗粒。在相对较短的时间内检测水中细菌的存在或数量，以提供用于近似瞬时指示或测量水质的装置或方法。

15. 发明申请

WO0144500A2 METHOD AND DEVICE FOR FLUID QUALITY MEASUREMENT 审中-公开
标题翻译：用于流体质量测量的方法和装置
公开(公告)号：WO0144500A2
公开(公告)日：2001-06-21
申请号：PCT/US0042822
申请日：2000-12-13
申请人： KIMBERLY CLARK CO
发明人： BRUNNER MICHAEL S , WEI NING , KOENIG DAVID W
IPC分类号： B03C1/01 , G01N33/18 , C12Q1/00
CPC分类号： B03C1/01 , C12Q1/22
摘要： The present invention is directed to a method and device for measuring water quality. The present invention utilizes displaceable particles located upon a substrate for measuring the water quality. The device allows the particles to be displaced by attaching bacteria to the substrate. The presence or the amount of bacteria in water is detected over a relatively short time period so as to provide a device or method for near instantaneous indication or measurement of water quality.
摘要翻译：本发明涉及一种测量水质的方法和装置。本发明利用位于基板上的位移性粒子来测量水质。该装置允许通过将细菌附着到基底来移动颗粒。在相对较短的时间内检测水中的细菌的存在或数量，以便提供近似即时指示或测量水质的装置或方法。

16. 发明申请

WO2014033574A3 PROTEIN STABILIZED PROBIOTICS AND PERSONAL CARE PRODUCTS 审中-公开
标题翻译：蛋白质稳定的生物和个人护理产品
公开(公告)号：WO2014033574A3
公开(公告)日：2014-04-24
申请号：PCT/IB2013056532
申请日：2013-08-09
申请人： KIMBERLY CLARK CO
发明人： KOENIG DAVID W , SCHOLL NEIL T , TOPOLKARAEV VASILY A , VANDEN HEUVEL AMY L
IPC分类号： A23L1/30 , A61K8/64 , C12N1/20
CPC分类号： A61K35/744 , A61K9/0034 , A61K35/742 , A61K35/745 , A61K35/747 , A61K36/064 , A61K36/48 , A61K36/899 , A61K38/48 , A61K2300/00
摘要： The present invention relates to a personal care product comprising a protein matrix wherein said protein matrix comprises at least one protein, at least one probiotic and a carrier fluid. The present invention also relates to the personal care product being a feminine care product particularly aimed at female urogenital health to treat or prevent vaginal infections. Oral and sinus infections, however, may also be benefited by the composition.
摘要翻译：本发明涉及包含蛋白质基质的个人护理产品，其中所述蛋白质基质包含至少一种蛋白质，至少一种益生菌和载体流体。本发明还涉及作为女性护理产品的个人护理产品，特别是针对女性泌尿生殖健康来治疗或预防阴道感染。然而，口服和鼻窦感染也可能受益于组合物。

17. 发明申请

WO02080668A3 ANTIMICROBIAL FORMULATIONS 审中-公开
标题翻译：抗生素配方
公开(公告)号：WO02080668A3
公开(公告)日：2003-02-20
申请号：PCT/US0204380
申请日：2002-02-12
申请人： KIMBERLY CLARK CO
发明人： KOENIG DAVID W , KROLL LISA M , OTTS DAVID R , COLE DOUGLAS B , STAHL KATHERINE D
IPC分类号： A61K9/70 , A01N25/30 , A01N25/34 , A01N37/02 , A01N37/10 , A01N57/12 , A01P1/00 , A01P3/00 , A61K31/19 , A61K31/661 , A61K31/765 , A61P31/02 , D06M13/188 , D06M13/192 , D06M13/207 , D06M13/295 , D06M13/328 , A01N37/04 , A01N37/06 , A01N37/36
CPC分类号： A01N57/12 , A01N25/30 , A01N25/34
摘要： Antimicrobial formulations, which may be essentially free of an antimicrobial active, comprising one or more proton donating agents and an alkyl phosphate anionic surfactant comprising a mono alkyl phosphate having the chemical structure: (I),wherein is a saturated or unsaturated straight chain or branched alkyl group having from about 8 to about 22 carbon atoms, x is a number from 0 to about 20, and and are independently selected from hydrogen, an alkali metal, or an alkanol amine, are provided and described herein. The formulations may be incorporated into wet wipes or various other personal care items such as facial tissue, bathroom tissue or feminine care products, or may be incorporated into lotions or soaps which may be applied directly to the skin. The antimicrobial formulations of the present invention have been found to have surprisingly high activity against numerous bacteria and other micoorganisms.
摘要翻译：可以基本上不含抗微生物活性物质的抗微生物制剂包含一种或多种质子供体剂和包含具有以下化学结构的单磷酸烷基酯的磷酸烷基酯阴离子表面活性剂：（I），其中R1是饱和或不饱和的直链具有约8至约22个碳原子的直链或支链烷基，x为0至约20的数，并且R 2和R 3独立地选自氢，碱金属或链烷醇胺并在此描述。制剂可以并入湿巾或各种其他个人护理用品，例如面巾纸，卫生纸巾或女性护理产品中，或者可以并入可直接施用于皮肤的洗剂或皂中。已经发现本发明的抗微生物制剂对许多细菌和其他微生物具有惊人的高活性。

18. 发明申请

WO0128511A9 SELECTIVE REMOVAL OF CONTAMINANTS FROM A SURFACE USING MAGNETS 审中-公开
标题翻译：使用磁铁从表面选择性去除污染物
公开(公告)号：WO0128511A9
公开(公告)日：2002-11-21
申请号：PCT/US0027105
申请日：2000-10-02
申请人： KIMBERLY CLARK CO
发明人： KOENIG DAVID W
IPC分类号： A61K8/02 , A61K9/50 , A61Q19/10 , C07K1/14 , A61K7/48
CPC分类号： C07K1/14 , A61K8/02 , A61K2800/47 , A61Q19/10
摘要： A system and method for removing contaminants from a surface. The system is designed to use particles having means thereon which are capable of selectively binding to a contaminant or contaminants of interest. The particles are applied to the surface whereupon the contaminants bind to the particle. When the particle is removed, the desired contaminants are also removed. Preferably, the present invention utilizes magnetic particles having iron therein. The particles may then be readily removed using magnets. The means for binding the contaminant to the particle preferably comprise a ligand or a charge specifically designed to remove the contaminant of interest. The particles may be included in a carrier to facilitate their application to the surface. The invention is especially useful for the removal of contaminants from skin.
摘要翻译：用于从表面去除污染物的系统和方法。该系统设计为使用能够选择性地结合污染物或感兴趣的污染物的具有其上的装置的颗粒。颗粒被施加到表面，因此污染物与颗粒结合。当除去颗粒时，也去除所需的污染物。优选地，本发明使用其中具有铁的磁性颗粒。然后可以使用磁体容易地除去颗粒。用于将污染物与颗粒结合的方法优选包含特异性设计用于去除感兴趣污染物的配体或电荷。颗粒可以包含在载体中以便于它们施加到表面。本发明特别可用于从皮肤去除污染物。

19. 发明申请

WO0128511A2 SELECTIVE REMOVAL OF CONTAMINANTS FROM A SURFACE USING MAGNETS 审中-公开
标题翻译：用磁铁从表面选择性除去污染物
公开(公告)号：WO0128511A2
公开(公告)日：2001-04-26
申请号：PCT/US0027105
申请日：2000-10-02
申请人： KIMBERLY CLARK CO
发明人： KOENIG DAVID W
IPC分类号： A61K8/02 , A61K9/50 , A61Q19/10 , C07K1/14 , A61K7/48
CPC分类号： C07K1/14 , A61K8/02 , A61K2800/47 , A61Q19/10
摘要： A system and method for removing contaminants from a surface. The system is designed to use particles having means thereon which are capable of selectively binding to a contaminant or contaminants of interest. The particles are applied to the surface whereupon the contaminants bind to the particle. When the particle is removed, the desired contaminants are also removed. Preferably, the present invention utilizes magnetic particles having iron therein. The particles may then be readily removed using magnets. The means for binding the contaminant to the particle preferably comprise a ligand or a charge specifically designed to remove the contaminant of interest. The particles may be included in a carrier to facilitate their application to the surface. The invention is especially useful for the removal of contaminants from skin.
摘要翻译：一种从表面去除污染物的系统和方法。该系统被设计成使用其上具有能够选择性地结合感兴趣的污染物或污染物的装置的颗粒。将颗粒施加到污染物与颗粒结合的表面上。当颗粒被去除时，所需的污染物也被去除。优选地，本发明利用其中具有铁的磁性粒子。然后可以使用磁体容易地去除颗粒。用于将污染物结合到颗粒上的装置优选包含专门设计用于除去感兴趣污染物的配体或电荷。颗粒可以被包含在载体中以促进它们施加到表面。本发明对于从皮肤去除污染物特别有用。

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