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11. 发明申请

WO1997000669A1 COMPOSITIONS AND METHODS FOR STABILIZING POLYMERS 审中-公开
标题翻译：用于稳定聚合物的组合物和方法
公开(公告)号：WO1997000669A1
公开(公告)日：1997-01-09
申请号：PCT/EP1996002539
申请日：1996-06-12
申请人： CIBA-GEIGY AG , TSAO, Fu-Pao
发明人： CIBA-GEIGY AG
IPC分类号： A61K09/00
CPC分类号： A61K9/0048 , C08K5/5317 , Y10S514/912 , Y10S514/913 , Y10S514/914 , Y10S514/915 , C08L33/02
摘要： Compositions and methods for reducing the decomposition rate of polymeric bioadhesives and viscosity enhancers, such as poly(acrylic acids). The compositions include at least one strong, stable chelating agent, preferably an organophosphorous compound such as diethylene triamine penta(methylene phosphonic acid). These biocompatible compositions are especially useful in the ophthalmic field.
摘要翻译：用于降低聚合物生物粘合剂和粘度增强剂（例如聚（丙烯酸））的分解速率的组合物和方法。组合物包括至少一种强稳定的螯合剂，优选有机亚磷化合物，例如二亚乙基三胺五（亚甲基膦酸）。这些生物相容性组合物特别适用于眼科领域。

12. 发明申请

WO1996030392A1 PROCESS FOR THE PRODUCTION OF COMBINATORIAL COMPOUND LIBRARIES 审中-公开
标题翻译：生产组合复合图书馆的过程
公开(公告)号：WO1996030392A1
公开(公告)日：1996-10-03
申请号：PCT/EP1996001154
申请日：1996-03-18
申请人： CIBA-GEIGY AG , RINK, Hans , VETTER, Dirk , GERCKEN, Bertold , FELDER, Eduard
发明人： CIBA-GEIGY AG
IPC分类号： C07K01/04
CPC分类号： C07K1/047 , A61K38/00 , B01J2219/005 , B01J2219/00572 , B01J2219/00596 , B01J2219/00725 , C40B40/10 , C40B70/00
摘要： Described is a process for the production of a library from a plurality of different units consisting of a solid or semisolid carrier (bead), a synthetic ligand and a binary information structure (tag), by means of which the building blocks of the ligand are coded, and the use of that library for searching for novel classes of active ingredient and individual active ingredients. Also described are compounds found using that process. The process is characterized by the use of element atoms or ions as binary tags which are bound non covalently to the beads. Their unique combination which can be measured by e.g. mass spectrometry codes for the specific ligand.
摘要翻译：描述了从由固体或半固体载体（珠粒），合成配体和二元信息结构（标签）组成的多个不同单元生产文库的方法，通过该文库，配体的结构单元编码，以及使用该库搜索新类别的活性成分和各种活性成分。还描述了使用该方法发现的化合物。该方法的特征在于使用元素原子或离子作为与珠不共价结合的二进制标记。它们独特的组合可以通过例如用于特定配体的质谱法编码。

13. 发明申请

WO1996029870A1 HERBICIDAL COMPOSITIONS 审中-公开
标题翻译：除草剂组合物
公开(公告)号：WO1996029870A1
公开(公告)日：1996-10-03
申请号：PCT/EP1996001086
申请日：1996-03-14
申请人： CIBA-GEIGY AG , GLOCK, Jutta , HUDETZ, Manfred , KERBER, Elmar
发明人： CIBA-GEIGY AG
IPC分类号： A01N43/54
CPC分类号： A01N43/54 , A01N43/66 , A01N25/32 , A01N2300/00
摘要： A selective herbicidal composition comprising, in addition to conventional formulation assistants, a mixture of a) a herbicidally effective amount of a herbicide of formula (I), or a salt or a stereoisomer of the compounds of formula (I), and b) to antagonise the herbicide, an antidotally effective amount of a safener of formula (IIa) of a compound of formula (IIb1), of a compound of formula (IIb2), of a compound of formula (IIc), of a compound of formula (IId), of a compound of formula (IIe), of a compound of formula (IIf), of a compound of formula (IIg), or of a compound of formula (IIh), wherein the substituents have the meanings claimed in claim 1.
摘要翻译：一种选择性除草组合物，除了常规制剂助剂外还包含a）除草有效量的式（I）除草剂或式（I）化合物的盐或立体异构体的混合物，和b）至拮抗除草剂，式（IIb1）化合物，式（IIb2）化合物，式（IIc）化合物，式（IId）化合物的式（IIa）化合物的安定剂）式（IIe）化合物，式（IIf）化合物，式（IIg）化合物或式（IIh）化合物，其中取代基具有权利要求1所述的含义。

14. 发明申请

WO1996029461A1 PROCESS FOR INCREASING THE SUN PROTECTION FACTOR OF CELLULOSIC FIBRE MATERIALS 审中-公开
标题翻译：增加纤维素纤维材料的保护因子的方法
公开(公告)号：WO1996029461A1
公开(公告)日：1996-09-26
申请号：PCT/EP1996000896
申请日：1996-03-04
申请人： CIBA-GEIGY AG , REINERT, Gerhard , FUSO, Francesco , HILFIKER, Rolf
发明人： CIBA-GEIGY AG
IPC分类号： D06P03/62
CPC分类号： D06P1/6536 , D06P1/628 , D06P1/6426 , D06P1/6495 , D06P1/65112 , D06P1/65118 , D06P1/65125 , D06P3/62
摘要： Process for increasing the sun protection factor of cellulosic fibre materials by treating the cellulosic fibre materials with at least one direct dye and at least one UV absorber.
摘要翻译：通过用至少一种直接染料和至少一种UV吸收剂处理纤维素纤维材料来增加纤维素纤维材料的防晒因子的方法。

15. 发明申请

WO1996027486A1 A CASTING DEVICE AND AN ADAPTER FOR A CASTING DEVICE 审中-公开
标题翻译：铸造装置和铸造装置的适配器
公开(公告)号：WO1996027486A1
公开(公告)日：1996-09-12
申请号：PCT/EP1996000772
申请日：1996-02-24
申请人： CIBA-GEIGY AG , SANER, Niklaus , WOMBWELL, Paul, Terrence
发明人： CIBA-GEIGY AG
IPC分类号： B29C33/00
CPC分类号： B29C33/0077 , B29C39/24
摘要： A casting device with which, by introducing a thermocurable plastics into a heatable casting mould (1), the plastics is thermally cured in that casting mould at least to such a degree that a casting moulded in that manner can be released from the mould, comprises a reservoir for the thermocurable plastics and a feed means for feeding plastics from the reservoir into the casting mould (1), which mould has an inlet opening that extends at least along a substantial portion of the length of the casting to be moulded, wherein the casting device comprises a separate adapter (2) in which the feed means (20, 221, 23) for the plastics is arranged and which can be connected to the casting mould (1) in such a manner that, when the adapter (2) has been connected, an outlet opening (23) provided in the adapter (2) is arranged sealed to and substantially congruent with the inlet opening of the casting mould (1).
摘要翻译：一种铸造装置，其中通过将可热固化的塑料引入可加热铸模（1）中，塑料在该铸模中热固化至少使得以这种方式模制的铸件可以从模具中释放的程度包括用于热固性塑料的储存器和用于将塑料从储存器输送到铸模（1）中的进料装置，该模具具有至少沿着待模制的铸件的长度的大部分延伸的入口，其中，浇铸装置包括单独的适配器（2），其中布置用于塑料的进料装置（20,221,23），并且可以以这样的方式连接到铸模（1），使得当适配器（2）设置在适配器（2）中的出口开口（23）被设置成与铸模（1）的入口密封并基本上一致。

16. 发明申请

WO1996026183A1 1-ARYL-2-ACYLAMINO-ETHANE COMPOUNDS AND THEIR USE AS NEUROKININ ESPECIALLY NEUROKININ 1 ANTAGONISTS 审中-公开
标题翻译： 1-ARYL-2-ACYLAMINO-ETHANE化合物及其作为神经元素特异性神经营养因子1拮抗剂
公开(公告)号：WO1996026183A1
公开(公告)日：1996-08-29
申请号：PCT/EP1996000555
申请日：1996-02-09
申请人： CIBA-GEIGY AG , GERSPACHER, Marc , VON SPRECHER, Andreas , ROGGO, Silvio , MAH, Robert , OFNER, Silvio , VEENSTRA, Siem, Jacob , BETSCHART, Claudia , AUBERSON, Yves , SCHILLING, Walter
发明人： CIBA-GEIGY AG
IPC分类号： C07C237/22
CPC分类号： C07D213/40 , C07C237/22 , C07C255/29 , C07C311/51 , C07C2601/02 , C07C2601/04 , C07C2601/08 , C07C2601/14 , C07C2601/18 , C07D209/08 , C07D209/12 , C07D209/20 , C07D211/22 , C07D211/44 , C07D211/48 , C07D211/58 , C07D213/70 , C07D215/46 , C07D223/12 , C07D231/12 , C07D231/38 , C07D233/56 , C07D235/16 , C07D235/28 , C07D239/42 , C07D241/20 , C07D249/08 , C07D295/13 , C07D295/135 , C07D295/185 , C07D401/12 , C07D403/12 , C07D417/12 , C07D471/10
摘要： 1-Aryl-2-acylamino-ethane compounds of formula (I), wherein R1 is aryl or heteroaryl; R2 is hydrogen, lower alkyl or aryl-lower alkyl; R3 is hydrogen, lower alkyl, aryl or heteroaryl; R4 is aryl or heteroaryl; X is C1-C7alkylene, C2-C7 alkenyline or C4-C7 alkanedienylene, and Am is an unsubstituted or mono- or di-substituted amino group, a disubstituted amino group being understood as including also an amino group in which the amino nitrogen is bonded into a ring, or a salt thereof, have valuable pharmaceutical properties and are especially effective as NK1 antagonists. They are prepared in a manner known per se.
摘要翻译：式（I）的1-芳基-2-酰基氨基 - 乙烷化合物，其中R 1是芳基或杂芳基; R2是氢，低级烷基或芳基 - 低级烷基; R3是氢，低级烷基，芳基或杂芳基; R4是芳基或杂芳基; X是C 1 -C 7亚烷基，C 2 -C 7链烯基或C 4 -C 7链烷二烯基，并且Am是未取代或单取代或二取代的氨基，二取代的氨基也被理解为也包括其中氨基氮键合的氨基成环或其盐具有有价值的药物性质，并且作为NK1拮抗剂是特别有效的。它们是以本身已知的方式准备的。

17. 发明申请

WO1996025549A1 PROCESS FOR INCREASING THE SUN PROTECTION FACTOR OF CELLULOSIC FIBRE MATERIALS 审中-公开
标题翻译：增加纤维素纤维材料的保护因子的方法
公开(公告)号：WO1996025549A1
公开(公告)日：1996-08-22
申请号：PCT/EP1996000399
申请日：1996-01-31
申请人： CIBA-GEIGY AG , REINERT, Gerhard , FUSO, Francesco , HILFIKER, Rolf
发明人： CIBA-GEIGY AG
IPC分类号： D06P01/642
CPC分类号： D06P1/38 , D06P1/628 , D06P1/6426 , D06P1/6495 , D06P1/65112 , D06P1/65118 , D06P1/65125 , D06P1/6536 , D06P3/66 , Y10S8/918
摘要： The present invention relates to a process for increasing the sun protection factor of cellulosic fibre materials, which comprises treating the cellulosic fibre materials with at least one reactive dye and at least one reactive UV absorber.
摘要翻译：本发明涉及增加纤维素纤维材料的防晒因子的方法，其包括用至少一种活性染料和至少一种反应性紫外线吸收剂处理纤维素纤维材料。

18. 发明申请

WO1996025390A1 PRODUCTION OF ENANTIOMERICALLY ENRICHED ORTHO-SUBSTITUTED 'alpha','alpha'-DIAROMATIC METHANOLS 审中-公开
标题翻译：生产高效液相色谱法制备的α，α-二甲基甲醇
公开(公告)号：WO1996025390A1
公开(公告)日：1996-08-22
申请号：PCT/EP1996000479
申请日：1996-02-06
申请人： CIBA-GEIGY AG
发明人： CIBA-GEIGY AG , SHIEH, Wen-Chung , CANTRELL, William, Rhodes , CARLSON, John, Alan
IPC分类号： C07C233/56
CPC分类号： C07C231/18 , C07B2200/07 , C07C37/002 , C07C213/08 , C07C233/56 , C07C39/12
摘要： A method of producing compounds of formula (I), wherein one of R1 and R2 is selected from -OH, -SH, and -NHR7; and the other of R1 and R2 is selected from H, -OH, -SH, -NHR7 and R8; R3 and R4 are each independently selected from R8; n and m are each independently 3; and each R5 and each R6 is independently selected from -OH, -SH, -NHR7, and R8; and R8 is as detailed in the specification; in enantiomerically enriched form, comprising reducing a compound of formula (II), wherein R1-R6 are defined as in formula (I), in the presence of B-haloisopinocampheylborane.
摘要翻译：制备式（I）化合物的方法，其中R 1和R 2中的一个选自-OH，-SH和-NHR 7; R 1和R 2中的另一个选自H，-OH，-SH，-NHR 7和R 8; R3和R4各自独立地选自R8; n和m各自独立地为3; 并且每个R 5和R 6各自独立地选自-OH，-SH，-NHR 7和R 8; R8如说明书所述; （II）的化合物，其中R 1 -R 6在式（I）中定义，在B-卤代异蒎烷樟脑硼烷的存在下。

19. 发明申请

WO1996024683A1 PROCESS FOR THE COMPLETE REMOVAL OF PROTECTIVE GROUPS ON NUCLEOSIDE DIPHOSPHATE AND TRIPHOSPHATE SUGARS 审中-公开
标题翻译：完全去除核苷酸二磷酸和三磷酸糖的保护基团的方法
公开(公告)号：WO1996024683A1
公开(公告)日：1996-08-15
申请号：PCT/EP1996000422
申请日：1996-02-01
申请人： CIBA-GEIGY AG , OEHRLEIN, Reinhold , BAISCH, Gabriele
发明人： CIBA-GEIGY AG
IPC分类号： C12P19/28
CPC分类号： C12P19/30 , C12P19/28
摘要： A process for the preparation of nucleoside diphosphate and triphosphate sugars wherein hydroxyl protective groups are removed enzymatically, and a process for the preparation of these sugars, which comprises coupling a nucleotide with a sugar-1-phosphate activated with a carbonyl bisazole and then removing the hydroxyl protective groups enzymatically.
摘要翻译：制备其中羟基保护基被酶促去除的二磷酸核苷和三磷酸糖的方法，以及制备这些糖的方法，其包括将核苷酸与用羰基双唑活化的糖-1-磷酸酯偶联，然后除去羟基保护基酶。

20. 发明申请

WO1996024076A1 CROSSLINKED TINTED POLYMERS 审中-公开
标题翻译：交联聚酯
公开(公告)号：WO1996024076A1
公开(公告)日：1996-08-08
申请号：PCT/EP1996000252
申请日：1996-01-23
申请人： CIBA-GEIGY AG , MÜLLER, Achim , PÖHLMANN, Thomas , SEIFERLING, Bernhard
发明人： CIBA-GEIGY AG
IPC分类号： G02B01/04
CPC分类号： G02B1/043 , C08F8/00 , C08F8/12 , C08F8/30 , C08F226/10 , C08F2800/20 , C08F2810/20 , C08F2810/30 , C08F2810/50 , C08L29/00 , C08F16/06 , C08F218/08
摘要： The invention relates to a novel process for the production of tinted mouldings, in particular tinted contact lenses, in which a crosslinkable tinted polymer comprising units containing a crosslinkable group and units containing a reactive dye radical is crosslinked in solution, and to tinted mouldings, in particular tinted contact lenses, obtainable by this process. The present invention likewise relates to novel crosslinkable tinted polymers comprising units containing a crosslinkable group and units containing a reactive dye radical which can be employed in the novel process, in particular derivatives of a polyvinyl alcohol having a molecular weight of at least about 2000, to crosslinked tinted polymers, either homopolymers or copolymers, made from these novel crosslinkable tinted polymers containing a reactive dye radical, a process for the preparation of the novel crosslinkable tinted polymers comprising units containing a crosslinkable group and units containing a reactive dye radical and the homopolymers and copolymers obtainable therefrom, to tinted mouldings made from said homopolymers or copolymers, in particular tinted contact lenses made from these homopolymers or copolymers, and to a process for the production of tinted contact lenses using said homopolymers or copolymers.
摘要翻译：本发明涉及一种用于生产着色模制品，特别是着色隐形眼镜的新方法，其中包含含有可交联基团的单元的交联着色聚合物和含有活性染料基团的单元在溶液中交联，并且在着色模制品中特定有色隐形眼镜，可通过该方法获得。本发明同样涉及包含可交联基团的单元和含有活性染料基团的单元的新型可交联着色聚合物，其可用于新方法，特别是分子量至少为约2000的聚乙烯醇衍生物，至交联着色聚合物，均聚物或共聚物，由含有活性染料基团的这些新型交联着色聚合物制成，制备包含可交联基团的单元的新交联着色聚合物的方法和含有活性染料基团的单元和均聚物，可从其获得的共聚物到由所述均聚物或共聚物制成的着色模制品，特别是由这些均聚物或共聚物制成的着色隐形眼镜，以及使用所述均聚物或共聚物生产着色隐形眼镜的方法。

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