专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

11. 发明申请

WO2012134869A3 CVT CONTROL USING STATE SPACE BASED GAIN SCHEDULING 审中-公开
标题翻译：使用基于状态空间的增益调度的CVT控制
公开(公告)号：WO2012134869A3
公开(公告)日：2012-12-27
申请号：PCT/US2012029725
申请日：2012-03-20
申请人： CATERPILLAR INC , LI WEI , HOFF BRIAN
发明人： LI WEI , HOFF BRIAN
IPC分类号： F16H59/36 , F16H59/44 , F16H61/66
CPC分类号： F16H61/465 , B60W10/06 , B60W10/103 , B60W30/1884 , B60W2710/1005 , B60W2710/1061 , F16H61/431 , F16H2059/366 , F16H2059/6853
摘要： An engine powered wheeled machine having improved engine over speed and under speed protection includes a parallel path transmission having a gear train with first and second transmission inputs and a transmission output, and including a hydraulic variator having a variator output driving the first transmission input, the hydraulic variator having a variator pump and a variator motor, the displacement of the variator pump being controlled by a variator actuator. The machine further includes an engine having an engine output driving the second transmission input and driving the variator pump and a controller for receiving one or more values indicative of one or more ranges of permissible engine speed, a value indicative of an actual engine speed, and a value indicative of the position of the variator actuator, with the controller being configured to control the position of the variator actuator based on state space gain mapping to maintain the engine speed within the one or more ranges of permissible engine speed.
摘要翻译：具有改进的发动机超速和低速保护的发动机动力轮式发动机包括具有带有第一和第二变速器输入和变速器输出的齿轮系的并行路径变速器，并且包括具有驱动第一变速器输入的变速器输出的液压变速器，具有变速泵和变速马达的液压变速器，变速泵的位移由变速器致动器控制。该机器还包括具有驱动第二变速器输入并驱动变速泵的发动机输出的发动机和用于接收表示允许的发动机转速的一个或多个范围，表示实际发动机转速的值的一个或多个值的控制器，以及指示变速器致动器的位置的值，其中控制器被配置为基于状态空间增益映射来控制变换器致动器的位置，以将发动机速度维持在允许的发动机转速的一个或多个范围内。

12. 发明申请

WO2008002329A3 ISOLATION AND EXPANSION OF ANIMAL CELLS IN CELL CULTURES 审中-公开
标题翻译：细胞培养中动物细胞的分离和扩增
公开(公告)号：WO2008002329A3
公开(公告)日：2008-07-17
申请号：PCT/US2006049500
申请日：2006-12-28
申请人： TISSUETECH INC , TSENG SCHEFFER , HE HUA , LI WEI , CHEN YING-TING , HAYASHIDA YASUTAKA
发明人： TSENG SCHEFFER , HE HUA , LI WEI , CHEN YING-TING , HAYASHIDA YASUTAKA
IPC分类号： C12N5/02 , C12N5/071 , C12N5/074
CPC分类号： C12N5/0621 , C12N5/0605 , C12N2500/90
摘要： Described are methods for isolating/purifying and expanding animal stem cells and stem-celHike cells. Isolation methods include conditions comprising preferentially digesting non-stem cells and non-stem-cell-like cells in a population and preferentially adhering stem cells and stem-cell-like cells in a population. Expansion methods include culturing such cells under conditions comprising modulation of TGF-ß signaling, inhibition of cell signaling mediated by p38 MAP kinase using small molecular weight inhibitors, expansion of the cells on human amniotic epithelial cells as feeder layers, control of cell seeding density, control of levels Of Ca2+ in the culture media, rapid adhesion on a substrate or by a combination of such conditions. More particularly, what is disclosed relates to methods and systems for expanding animal cells in ex vivo cell cultures, while preventing cellular differentiation, and selectively enriching stem cells. The embodiments also disclose a culture system for ex vivo expansion of limbal epithelial cells or mesenchymal cells, as well as surgical grafts made there from.
摘要翻译：描述了分离/纯化和扩增动物干细胞和干细胞样细胞的方法。分离方法包括包含优先消化群体中的非干细胞和非干细胞样细胞并且优先将干细胞和干细胞样细胞粘附于群体中的条件。扩增方法包括在包含TGF-β信号传导的调节，使用小分子量抑制剂抑制由p38MAP激酶介导的细胞信号传导的条件下培养此类细胞，作为饲养层的细胞在人羊膜上皮细胞上的扩增，细胞接种密度的控制，控制培养基中Ca 2+的水平，在基质上的快速粘附或通过这些条件的组合。更具体地，公开的内容涉及用于在体外细胞培养物中扩增动物细胞，同时防止细胞分化和选择性富集干细胞的方法和系统。这些实施方案还公开了用于离体扩展角膜缘上皮细胞或间充质细胞的培养系统，以及由其制造的手术移植物。

13. 发明申请

WO2008064577A1 A METHOD AND AN APPARATUS FOR ADJUSTING QUANTIZATION QUALITY IN ENCODER AND DECODER 审中-公开
标题翻译：一种用于调节编码器和解码器中量化质量的方法和装置
公开(公告)号：WO2008064577A1
公开(公告)日：2008-06-05
申请号：PCT/CN2007003799
申请日：2007-12-26
申请人： HUAWEI TECH CO LTD , LI WEI , XU LIJING , ZHANG QING , XU JIANFENG , SANG SHENGHU , DU ZHENGZHONG , ZOU YAOBANG , LIU PEILIN
发明人： LI WEI , XU LIJING , ZHANG QING , XU JIANFENG , SANG SHENGHU , DU ZHENGZHONG , ZOU YAOBANG , LIU PEILIN
IPC分类号： G10L19/00 , G10L19/02 , G10L19/032
CPC分类号： G10L19/032
摘要： A method for adjusting quantization quality in encoder. It comprises adjusting the first sample values to be encoded using two or more scale factors, and quantizing the first sample values adjusted to acquire quantized sample values. Then, getting rid of the influence of scale factors for the quantized sample values to get the second sample values, and based on the first sample values and the second sample values to get the global gain. Subsequently, encoding the quantized sample values, the two or more scale factors and the global gain into bit stream. Furthermore, the method for adjusting quantization quality in decoder and the apparatus for adjusting quantization quality in encoder and decoder can reduce the practical complication sharply, and adjust better quantization quality of important section, and acquire better encoding effect.
摘要翻译：一种调整编码器量化质量的方法。它包括使用两个或更多比例因子调整要编码的第一样本值，并量化调整以获取量化样本值的第一样本值。然后，消除量化因子对量化样本值的影响，得到第二个样本值，并根据第一个样本值和第二个样本值得到全局增益。随后，将量化的样本值，两个或更多比例因子和全局增益编码为比特流。此外，用于调整解码器中的量化质量的方法和用于调整编码器和解码器中的量化质量的装置可以大大降低实际的复杂度，并且调整较好的重要部分的量化质量，并获得更好的编码效果。

14. 发明申请

WO2007092435A3 11-BETA HSD1 INHIBITORS 审中-公开
标题翻译： 11-BETA HSD1抑制剂
公开(公告)号：WO2007092435A3
公开(公告)日：2007-12-27
申请号：PCT/US2007003134
申请日：2007-02-07
申请人： WYETH CORP , XIANG JASON SHAOYUN , SAIAH EDDINE , TAM STEVE Y , MCKEW JOHN C , CHEN LIHREN , IPEK MANUS , LEE KATHERINE , LI HUAN-QUI , LI JIANCHANG , LI WEI , MANSOUR TAREK SUHAYL , SURI VIPIN , VARGAS RICHARD , WU YUCHUAN , WAN ZHAO-KUI , LEE JINBO , BINNUN EVA , WILSON DOUGLAS P
发明人： XIANG JASON SHAOYUN , SAIAH EDDINE , TAM STEVE Y , MCKEW JOHN C , CHEN LIHREN , IPEK MANUS , LEE KATHERINE , LI HUAN-QUI , LI JIANCHANG , LI WEI , MANSOUR TAREK SUHAYL , SURI VIPIN , VARGAS RICHARD , WU YUCHUAN , WAN ZHAO-KUI , LEE JINBO , BINNUN EVA , WILSON DOUGLAS P
IPC分类号： C07D211/96 , A61K31/44 , A61K31/495 , C07D295/22 , C07D401/04
CPC分类号： C07D211/96 , C07D295/26 , C07D401/04 , C07D403/02 , C07D409/02 , C07D413/02
摘要： This invention relates to inhibiting 11ßHSD1.
摘要翻译：本发明涉及抑制11βHSD1。

15. 发明申请

WO2013142072A3 LUGGAGE VISUALIZATION AND VIRTUAL UNPACKING 审中-公开
标题翻译：行货可视化和虚拟解包
公开(公告)号：WO2013142072A3
公开(公告)日：2014-11-20
申请号：PCT/US2013029494
申请日：2013-03-07
申请人： SIEMENS CORP , LI WEI , PALADINI GIANLUCA
发明人： LI WEI , PALADINI GIANLUCA
IPC分类号： G06T19/00
CPC分类号： G06T15/08 , G01N23/046 , G01N2223/419 , G01N2223/42 , G01N2223/639 , G01N2223/643 , G06T19/00 , G06T2207/10072 , G06T2207/30112
摘要： Methods and systems for luggage visualization perform virtual unpacking by visually moving an object image away from its original pose. A scanned 3D volume is segmented guided by a confidence measure to create a label volume whose voxels specify the detected object IDs. The luggage dataset and the label volume are visualized by volume rendering. Using an automatic coloring algorithm, any pair of objects whose projections are adjacent in an image are assigned distinct hues. A layered framework efficiently renders a scene mixed with packed luggage, animated unpacking objects, and already unpacked objects put aside for further inspection. A GPU is used to automatically select objects that are not blocked by others and can be unpacked.
摘要翻译：用于行李可视化的方法和系统通过视觉上将物体图像远离其原始姿态进行虚拟拆包。扫描的3D体积由置信度量度引导，以创建体素，其体素指定检测到的对象ID。行李数据集和标签卷可通过体积渲染来显示。使用自动着色算法，其投影在图像中相邻的任何一对对象被分配不同的色调。分层框架有效地将场景与包装的行李，动画的拆包对象以及已经打包的对象放在一起进行进一步检查。 GPU用于自动选择未被其他人阻止的对象，并可以解压缩。

16. 发明申请

WO2013088210A1 AUTOMATIC NETWORKING APPARATUS AND SYSTEM FOR VEHICLES 审中-公开
标题翻译：车辆自动联网装置和系统
公开(公告)号：WO2013088210A1
公开(公告)日：2013-06-20
申请号：PCT/IB2012000684
申请日：2012-04-04
申请人： SHANGAI BAOLONG AUTOMOTIVE CORP , HU JUNFENG , SHI WEIHUA , LI WEI
发明人： HU JUNFENG , SHI WEIHUA , LI WEI
IPC分类号： B60R16/023 , B60D1/62 , B60K35/00 , B60P9/00 , H04L12/28
CPC分类号： B60D1/62 , H04L67/12
摘要： A vehicle automatic networking apparatus with a first component and a second replaceable component includes a first identity recognition module on the first component and a second identity recognition module on the second component. The second module in a networking mode transmits a low frequency wake up signal through a low frequency signal transmission circuit to wake up the first module. A first identity recognition module low frequency sensor circuit senses the low frequency wake up signal, and responds by transmitting an identity code of the first component through a low frequency signal transmission circuit. A second module low frequency signal receiving circuit receives and stores the first component identity code. In a following data transmission, the second module sends data with the identity code, and a first component receiving apparatus identifies it. The first and second modules are both located rearward of a second component connection hitch.
摘要翻译：具有第一组件和第二可替换组件的车辆自动联网设备包括在第一组件上的第一身份识别模块和在第二组件上的第二身份识别模块。处于联网模式的第二模块通过低频信号传输电路传输低频唤醒信号以唤醒第一模块。第一身份识别模块低频传感器电路感测低频唤醒信号，并且通过经由低频信号传输电路传输第一组件的识别码来响应。第二模块低频信号接收电路接收并存储第一组件识别码。在接下来的数据传输中，第二模块发送带有身份代码的数据，第一组件接收设备识别它。第一和第二模块都位于第二组件连接挂钩的后方。

17. 发明申请

WO2012051207A3 FRAGMENT OF SECRETED HEAT SHOCK PROTEIN-90ALPHA (Hsp90ALPHA) AS VACCINES OR EPITOPE FOR MONOCLONAL ANTIBODY DRUGS OR TARGET FOR SMALL MOLECULE DRUGS AGAINST A RANGE OF SOLID HUMAN TUMORS 审中-公开
标题翻译：分散的热休克蛋白-90ALPHA（Hsp90ALPHA）作为疫苗或抗生素用于单克隆抗体药物或靶向小分子药物对抗人类肿瘤范围的片段
公开(公告)号：WO2012051207A3
公开(公告)日：2012-12-06
申请号：PCT/US2011055822
申请日：2011-10-11
申请人： UNIV SOUTHERN CALIFORNIA , LI WEI , WOODLEY DAVID T , CHEN MEI
发明人： LI WEI , WOODLEY DAVID T , CHEN MEI
IPC分类号： A61K38/16 , A61K48/00
CPC分类号： C07K14/435 , A61K31/713 , A61K39/0005 , C07K14/47 , C07K16/18 , C07K2317/76 , G01N33/57484 , G01N33/92 , G01N2333/70596 , G01N2500/10
摘要： The invention provides methods for treating HIF-1a-overexpressing human tumors, inhibiting HIF-1a-overexpressing tumor invasion and preventing tumor metastasis, and/or promoting tumor prophylaxis, using various types of inhibitors against the Hsp90a from the tumors.
摘要翻译：本发明提供了使用各种类型的针对肿瘤Hsp90a的抑制剂治疗HIF-1a过表达人类肿瘤，抑制HIF-1a过表达肿瘤浸润和预防肿瘤转移和/或促进肿瘤预防的方法。

18. 发明申请

WO2012139244A1 COSMETIC COMPOSITION 审中-公开
标题翻译：化妆品组合物
公开(公告)号：WO2012139244A1
公开(公告)日：2012-10-18
申请号：PCT/CN2011000623
申请日：2011-04-11
申请人： PROCTER & GAMBLE COMMPANY , LI WEI , XIE YI , HA ROBERT BAO KIM
发明人： LI WEI , XIE YI , HA ROBERT BAO KIM
IPC分类号： A61K8/29 , A61K8/25 , A61K8/27 , A61K8/28 , A61K8/34 , A61K8/37 , A61K8/42 , A61K8/891 , A61Q1/02 , A61Q5/00 , A61Q19/00
CPC分类号： A61K8/0254 , A61K8/27 , A61K8/28 , A61K8/29 , A61K8/31 , A61K8/585 , A61K8/891 , A61K2800/412 , A61K2800/436 , A61Q1/00 , A61Q5/02 , A61Q5/12 , A61Q9/02 , A61Q19/00 , A61Q19/10
摘要： A cosmetic composition comprising: from about 0.1% to about 5% of an colored interference pigment; from about 0.1 % to about 10% of a non-interference pigment concentrate; from about 10 % to about 90% of a cosmetically acceptable vehicle; wherein the cosmetic composition has a contrast ratio of 10 or less and has a viscosity of no less than about 40,000 cps. A method of presenting a color transformation of a cosmetic composition during its application, comprising a step of applying the cosmetic composition onto skin.
摘要翻译：一种化妆品组合物，其包含：约0.1％至约5％的有色干涉颜料; 约0.1％至约10％的非干涉颜料浓缩物; 约10％至约90％的化妆品可接受的载体; 其中所述化妆品组合物具有10以下的对比度，并且具有不低于约40,000cps的粘度。一种在其应用期间呈现化妆品组合物的颜色变换的方法，包括将化妆品组合物施用到皮肤上的步骤。

19. 发明申请

WO2012027481A1 COMPOUNDS FOR TREATMENT OF CANCER 审中-公开
标题翻译：用于治疗癌症的化合物
公开(公告)号：WO2012027481A1
公开(公告)日：2012-03-01
申请号：PCT/US2011048980
申请日：2011-08-24
申请人： GTX INC , UNIV TENNESSEE REASEARCH FOUNDATION , DALTON JAMES T , MILLER DUANE D , LI CHIEN-MING , AHN SUNJOO , LU YAN , WANG ZHAO , CHEN JIANJUN , LI WEI , DUKE CHARLES
发明人： DALTON JAMES T , MILLER DUANE D , LI CHIEN-MING , AHN SUNJOO , LU YAN , WANG ZHAO , CHEN JIANJUN , LI WEI , DUKE CHARLES
IPC分类号： A01N43/50 , A61K31/415
CPC分类号： A61K31/415 , C07D233/60 , C07D263/32 , C07D277/24 , C07D277/42 , C07D403/04 , C07D403/12 , C07D417/04 , C07D417/12 , C07D417/14
摘要： The present invention relates to novel compounds having anti-cancer activity, methods of making these compounds, and their use for treating cancer and drug-resistant tumors, e.g. melanoma, metastatic melanoma, drug resistant melanoma, prostate cancer and drug resistant prostate cancer.
摘要翻译：本发明涉及具有抗癌活性的新化合物，制备这些化合物的方法及其用于治疗癌症和药物抗性肿瘤的用途，例如，黑素瘤，转移性黑素瘤，耐药性黑素瘤，前列腺癌和耐药前列腺癌。

20. 发明申请

WO2010115046A2 VACCINE COMPOSITIONS AND METHODS OF USE THEREOF 审中-公开
标题翻译：疫苗组合物及其使用方法
公开(公告)号：WO2010115046A2
公开(公告)日：2010-10-07
申请号：PCT/US2010029694
申请日：2010-04-01
申请人： UNIV MIAMI , DAFTARIAN PIROUZ MOHAMMAD , SERAFINI PAOLO , LEMMON VANCE PAUL , LI WEI , KAIFER ANGEL , BLOMBERG BONNIE BETH , PEREZ VICTOR L
发明人： DAFTARIAN PIROUZ MOHAMMAD , SERAFINI PAOLO , LEMMON VANCE PAUL , LI WEI , KAIFER ANGEL , BLOMBERG BONNIE BETH , PEREZ VICTOR L
IPC分类号： A61K39/145
CPC分类号： A61K39/0011 , A61K39/12 , A61K39/145 , A61K2039/53 , A61K2039/55516 , A61K2039/55555 , A61K2039/645 , C08G83/006 , C12N2760/16022 , C12N2760/16034 , G01N2333/70539
摘要： Nanoparticle -based vaccines, compositions, kits and methods are used for the effective delivery of one or more antigens in vivo for vaccination and antibody (e.g., monoclonal antibody) production, and for the effective delivery of peptides, proteins, siRNA, RNA or DNA to PAPCs or MHC class II positive cells (e.g. tumor cells). Antigens may be, for example, DNA that results in expression of the gene of interest and induction of a robust and specific immune response to the expressed protein in a subject (e.g., mammal). Antigens may also be immunogenic peptides or polypeptides that are processed and presented. In one embodiment, a nanoparticle -based method to deliver antigens in vivo as described herein includes injection of a vaccine composed of a DNA encoding at least one antigen, or at least one antigenic peptide or polypeptide conjugated to a charged dendrimer (e.g., PADRE-derivatized dendrimer) that is also conjugated to a T helper epitope (e.g., PADRE). Negatively-charged plasmids bind naturally to a positively-charged PADRE-dendrimer, while peptide or polypeptide antigens can be chemically linked to the PADRE-dendrimer if they are not negatively-charged. Alternatively, negatively-charged dendrimers may be used. The compositions, kits, vaccines and methods described herein have both prophylactic and treatment applications, i.e., can be used as a prophylactic to prevent onset of a disease or condition in a subject, as well as to treat a subject having a disease or condition. A vaccine as described herein can be used to mount an immune response against any infectious pathogen or cancer.
摘要翻译：基于纳米颗粒的疫苗，组合物，试剂盒和方法用于体内有效递送一种或多种抗原用于疫苗接种和抗体（例如单克隆抗体）生产以及有效递送肽，蛋白质，siRNA，RNA或DNA 到PAPC或MHC II类阳性细胞（例如肿瘤细胞）。例如，抗原可以是导致感兴趣基因表达并诱导受试者（例如哺乳动物）中所表达的蛋白质的强烈和特异性免疫应答的DNA。抗原也可以是经过处理和呈递的免疫原性肽或多肽。在一个实施方案中，如本文所述的体内递送抗原的基于纳米粒子的方法包括注射由编码至少一种抗原的DNA组成的疫苗或缀合至带电荷的树状聚体的至少一种抗原性肽或多肽（例如PADRE- 衍生的树枝状聚合物），其也与T辅助表位（例如，PADRE）缀合。带负电荷的质粒自然结合带正电荷的PADRE-树状聚体，而肽或多肽抗原可以化学连接至PADRE-树状聚合物（如果它们不带负电荷的话）。或者，可以使用带负电的树枝状聚合物。本文所述的组合物，试剂盒，疫苗和方法具有预防和治疗应用，即可用作预防以预防对象中疾病或病症的发作，以及治疗患有疾病或病症的对象。如本文所述的疫苗可用于产生针对任何感染性病原体或癌症的免疫应答。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式