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    • 15. 发明申请
    • STYRENE DERIVATIVE AND SALTS THEREOF
    • 苯乙烯衍生物及其盐
    • WO1994010157A1
    • 1994-05-11
    • PCT/JP1993001572
    • 1993-10-29
    • TAIHO PHARMACEUTICAL CO., LTD.SUZUKI, MasahiroNOZAKI, KenziHOSOYA, ToshiyukiSUZUKI, TakashiBASAKI, YuziKOZIMA, MitiyoMATSUURA, Naosuke
    • TAIHO PHARMACEUTICAL CO., LTD.
    • C07D261/08
    • C07D413/12C07D261/08Y02P20/55
    • A styrene derivative represented by general formula (1), a salt thereof, a process for producing the same, lipoxygenase and cyclo-oxygenase inhibitors each containing an effective dose of the derivative and a pharmaceutical carrier, and a method of inhibiting lipoxygenase and cyclo-oxygenase by administering the derivative R1 and R2 may be the same or different from each other and each represents hydrogen, lower alkoxy, halogen or lower alkyl; R3s may be the same or different from each other and each represents hydroxy, lower alkoxy, lower alkyl, lower alkoxycarbonyloxy, lower acyloxy, a di(lower alkyl) phosphate residue or an optionally protected amino acid residue; 1 represents an integer of 0 to 5; m represents an integer of 0 to 5; X represents a single bond or a group represented by the general formula -N(Z)CO- wherein Z represents (CH2)nA wherein A represents hydrogen, carboxy, di- or mono(lower alkyl) carbamoyl, carbamoyl, lower alkoxycarbonyl, cyano, lower alkoxy, N-acylamino, optionally substituted phenyl, pyridyl or thienyl, and n represents an integer of 0 to 5; and Y represents -C(Z')=CH-, -CH=CH- C(Z')=CH- or -C(Z')=CH-H=CH- wherein Z' is the same as Z, provided the case where both of Z and Z' are hydrogen when n is 0 is excluded.
    • 由通式(1)表示的苯乙烯衍生物,其盐,其制备方法,脂氧合酶和环加氧酶抑制剂,各自含有有效剂量的衍生物和药物载体,以及抑制脂氧合酶和环加氧酶的方法, 通过施用衍生物R1和R2可以相互或不同,并且各自代表氢,低级烷氧基,卤素或低级烷基; R 3可以彼此相同或不同,并且各自表示羟基,低级烷氧基,低级烷基,低级烷氧基羰基氧基,低级酰氧基,二(低级烷基)磷酸酯残基或任选保护的氨基酸残基; 1表示0〜5的整数, m表示0〜5的整数, X表示单键或由通式-N(Z)CO-表示的基团,其中Z表示(CH 2)n A,其中A表示氢,羧基,二或单(低级烷基)氨基甲酰基,氨基甲酰基,低级烷氧基羰基,氰基 ,低级烷氧基,N-酰基氨基,任选取代的苯基,吡啶基或噻吩基,n表示0至5的整数; 并且Y表示-C(Z')= CH-,-CH = CH-C(Z')= CH-或-C(Z')= CH-H = CH-,其中Z'与Z相同, 当n为0时Z和Z'都为氢的情况被排除。
    • 17. 发明申请
    • METHOD OF AND DEVICE FOR MEASURING EXTREMELY SMALL QUANTITY OF OXYGEN IN GAS
    • 用于测量气体中极少数量的氧气的方法和装置
    • WO1991003731A1
    • 1991-03-21
    • PCT/JP1990001083
    • 1990-08-27
    • NIPPON SANSO KABUSHIKI KAISHASUZUKI, TakashiITOH, KenkichiSASAKI, Hajime
    • NIPPON SANSO KABUSHIKI KAISHA
    • G01N21/76
    • G01N21/766Y10T436/207497Y10T436/209163Y10T436/25625
    • This invention relates to a method of and device for measuring an extremely small quantity of oxygen in gas depending on the intensity of light generated when yellow phosphor vapor is reacted with oxygen in the sample gas. Together with the sample gas, a fixed quantity of oxygen is continously fed to the reaction chamber and reacted with yellow phosphor vapor so that the intensity of light generated by said reaction is measured. Density of oxygen in gas is found from the difference between a value of measured intensity of light and that of the intensity of light generated on reaction of yellow phosphor vapor with added oxygen, or from the difference between oxygen density obtained from the measured value and that of added oxygen. Addition of a fixed quantity of oxygen is performed in such process that pre-conditioned oxygen-containing gas is fed together with a fixed quantity of sample gas, or oxygen in the atmosphere is adapted to permeate an oxygen permeable film provided in the sample gas feeding system or in the yellow phosphor vapor feeding system. An extremely small quantity of oxygen under several ppb in the sample gas can continously be measured at high precision.
    • 本发明涉及一种用于测量气体中极少量的氧气的方法和装置,这取决于当黄色磷光体蒸气与样品气体中的氧气反应时产生的光的强度。 与样品气体一起,将固定量的氧连续地供给到反应室中,并与黄色磷光体蒸气反应,从而测量由所述反应产生的光的强度。 气体中的氧气密度是根据测得的光强值与黄色磷光体蒸汽与添加氧反应产生的光强度之差,或者从测量值得到的氧浓度差与 的添加氧气。 在预定的含氧气体与固定量的样品气体一起进料的过程中进行固定量的氧的添加,或者大气中的氧气适于透过设置在样品气体供给中的氧气可渗透膜 系统或在黄色磷光体蒸气供给系统中。 可以连续地高精度地测量样品气体中几ppb下的极少量的氧气。